[Characteristics of viral hepatitis in addicts with consideration of lymphocyte membrane condition].

Abstract:

AIM:To study changes in the condition of lymphocyte membranes of patients with acute viral hepatitis B (AVHB) in narcotic addicts. MATERIALS AND METHODS:136 patients with AVHB have been examined for endogenic intoxication (plasma levels of middle-size molecular peptides, urine levels of red cells). 74% of the examinees had practiced parenteral injections of opium substitutes. Measurements were made of lymphocyte levels of malonic dialdehyde and superoxide dismutase activity characterizing free radical lipid peroxidation, enzymes of the main metabolic cycles. RESULTS:AVHB addicts often display antibodies to hepatitis C virus, high indices of endogenic intoxication. CONCLUSION:Viral hepatitis was associated with enhanced intensity of lymphocyte membrane lipid peroxidation correlating with the disease severity and duration irrespective of concomitant drug addiction. Early convalescence in drug addicts ran with persisting metabolic disturbances in the immunocompetent cells. This is a pathogenetic sign of the disease transformation to the chronic form.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Antonova TV,Nikolaenko SL,Bol'shakova AI

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

21-4

issue

11

eissn

0040-3660

issn

2309-5342

journal_volume

70

pub_type

杂志文章
  • [Trans isomers of unsaturated fatty acids increase the risk of atherosclerosis-related circulatory system diseases].

    abstract::The paper provides a review of the literature on a relevant non-drug prevention problem, namely the negative effect of trans isomers of unsaturated fatty acids (trans-UFA) on the risk of circulatory system diseases (CSD) and other chronic noncommunicable diseases. It gives data on the specific features of the structur...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Perova NV,Metel'skaia VA,Boĭtsov SA

    更新日期:2013-01-01 00:00:00

  • [Prevalence of bronchial asthma and allergic rhinitis in the adult population of St. Petersburg].

    abstract:AIM:To evaluate prevalence of bronchial asthma (BA) and allergic rhinitis (AR) among adult population of St-Petersburg. MATERIAL AND METHODS:Responders to ECRHS and B. Sibbald & E. Rink questionnaires who gave at least one positive answer were examined clinically, functionally and allergologically. A total of 3634 res...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Fedoseev GB,Emel'ianov AV,Sergeeva GR,Ivanova NI,Zibrina TM,Maksimenko IN,Tsukanova IV

    更新日期:2003-01-01 00:00:00

  • [The effectiveness of target therapy in patients with severe allergic asthma].

    abstract::The purpose of study was to analyze own clinical experience and assess the effectiveness in treatment of severe very poorly controlled allergic asthma patients with omalizumab. The effectiveness of biologic treatment with omalizumab was analyzed in 10 patients with severe very poorly controlled allergic asthma. It has...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/00403660.2019.12.000451

    authors: Skorokhodkina OV,Valeeva AR,Luntsov AV,Pozdnyak VA

    更新日期:2019-12-15 00:00:00

  • [Mechanism of action of endotoxins in chronic renal failure].

    abstract::Altogether 76 patients with terminal chronic renal failure (CRF) were examined for the intensity of endogenous intoxication and its action mechanism in blood serum. To determine the degree of intoxication, use was made of neuromuscular preparations of Rana temporaria. In order to study the action mechanism of the toxi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Aklaev RN,Usmanov PB,Kim VF,Kalikulov D,Kazakov I

    更新日期:1989-01-01 00:00:00

  • [Clinical function of the myocardium and cardio- and hemodynamics in patients with pectus carinatum deformity].

    abstract::Seventy patients with pectus carinatum were examined. All the patients demonstrated the minimal signs of connective tissue deficiency. The ECG readings showed incomplete blockade of the bundle of His, ventricular extrasystole, WPW and CLC syndromes, and metabolic alterations in the myocardium. Mitral valve prolapse wa...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Iakovlev VM,Nechaeva GI,Viktorova IA

    更新日期:1990-01-01 00:00:00

  • [New findings in the pathogenesis of chronic glomerulonephritis].

    abstract::30 untreated patients with membranoproliferative glomerulonephritis (MPGN) with isolated urinary syndrome were examined for cellular and humoral immunity. There was a significant (p < 0.05) reduction of the number of T-helpers/inductors (T4/4B4) and early undifferentiated lymphoid precursors with the marker enzyme. T-...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Riabov SI,Rakitianskaia IA,Nikitina NA,Travkina ES

    更新日期:1994-01-01 00:00:00

  • [Anti-C1q antibodies in patients with systemic lupus erythematosus treated by rituximab].

    abstract:AIM:To determine the time course of changes in the blood levels of antibodies (Ab) to complement component C1q (a-C1q) in patients with systemic lupus erythematosus (SLE) during rituximab (RTM) therapy and the association with organ injuries in SLE. SUBJECTS AND METHODS:The study involved 41 patients (3 men and 38 wom...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tsanyan ME,Torgashina AV,Aleksandrova EN,Soloviev SK,Nasonov EL

    更新日期:2013-01-01 00:00:00

  • [Characteristics of the periodic motor activity of the upper gastrointestinal tract in peptic ulcer and chronic pancreatitis].

    abstract::A study was made of the periodical motor activity (PMA) of the antral part of the stomach (APS) and duodenum (D) using a manometric system of 4 continuously perfused catheters in 96 patients with peptic ulcer, 20 patients with ulcer of the body of the stomach, 26--with chronic pancreatitis, and in 16 healthy controls....

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Fisher AA,Karuna IuV

    更新日期:1988-01-01 00:00:00

  • [Changes in the functional status of the adrenal glands in patients with chronic renal failure during the treatment by programmed hemodialysis].

    abstract::A study was made of adrenal function in 2 groups of patients with chronic renal insufficiency on programmed hemodialytic therapy. Insufficiency of gluco- and mineralo-corticoid function of the adrenal glands and hyperfunction of their medulla developed in patients with normal BP and controlled hypertension. In patient...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Neĭmark MI

    更新日期:1988-01-01 00:00:00

  • [Increased arterial stiffness is a significant but not obligatory factor of arterial hypertension in persons over 60 years of age].

    abstract:AIM:To ascertain whether high arterial rigidity is obligatory in arterial hypertension (AH) and the presence of AH is obligatory in patients with rigid arteries. MATERIAL AND METHODS:Volume sphygmography (VS) was made in 153 patients aged 60-86 years: 96 patients with untreated AH of degree 1-3 (40 males aged 71.0 +/-...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Boĭtsov SA,Rogoza AN,Kanishcheva E,Luk'ianov MM

    更新日期:2011-01-01 00:00:00

  • [Effect of nifedipine in chronic left ventricular insufficiency in patients with post-infarction heart aneurysm].

    abstract::A study was made of a vasodilating effect of nifedipine on the hemodynamics of 30 patients with chronic postinfarction left ventricular aneurysm, with chronic cardiovascular insufficiency of the II-III degree according to NYHA. A mean value of the acontractile segment on ventriculograms was 32.5 +/- 1.7%. The main par...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Soopyl'd IuKh,Laane EIa,Uuskiula MM,Altraia EM

    更新日期:1986-01-01 00:00:00

  • [Serum lipid spectrum in HBsAg carrying patients with alcoholism].

    abstract:AIM:To reveal the effect of HBsAg on the serum lipid spectrum in alcoholics. MATERIALS AND METHODS:The serum lipid spectrum was studied in 30 alcoholics who were HBsAg carries, 50 alcoholics without HBsAg and 40 healthy individuals. RESULTS:Unlike alcoholic patients without HBsAg, those who were HBsAg carriers had hi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Makarov VK

    更新日期:2002-01-01 00:00:00

  • [The role of the renin-angiotensin system in the pathogenesis of nephrotic syndrome].

    abstract::The state of the renin-angiotensin system (RAS) was studied in 102 patients with chronic glomerulonephritis with the nephrotic syndrome (NS) with relation to a phase of the edematous syndrome and sodium balance. Heterogeneity of patients with NS was shown with regard to RAS activity and the circulating blood volume in...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kutyrina IM,Klepikov PV,Tareeva IE

    更新日期:1988-01-01 00:00:00

  • [Regulators of fibrinolysis in chronic viral pathology of the liver].

    abstract:AIM:To investigate a clinicopathogenetic role of fibrinolysis regulators in chronic viral hepatitis (CVH) and viral cyrrhosis of the liver (CL). MATERIAL AND METHODS:Seventy patients entered the study: 10 patients with CVH B, 33--with CVH C, 6--with CVH D, 21--with viral CL (HCV-associated in 14 cases and HBV-associat...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Iagoda AV,Koroĭ PV

    更新日期:2009-01-01 00:00:00

  • [Aortocoronary shunting in unstable and early postinfarction angina pectoris due to lesion of a coronary artery].

    abstract::Aortocoronary shunting was performed in 15 patients with unstable and early postinfarction angina pectoris. Coronarography revealed an isolated lesion of a coronary artery in all the patients. Two years after the operation the patients had no angina pectoris; no myocardial infarctions occurred. ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Solov'ev GM,Mikheev AA,Petrovskiĭ PF,Klembovskiĭ AA,Simonov VI,Travin NO,Alishin II,Pisareva NS

    更新日期:1990-01-01 00:00:00

  • [The role of inflammation factors in development of acute coronary syndrome in patients with type 2 diabetes mellitus and impaired glucose tolerance].

    abstract:AIM:To study the levels of inflammatory markers in acute coronary syndrome (ACS) and 6 months after its regression in patients with diabetes mellitus (DM) type 2; to evaluate effects of anxiodepressive disorders on inflammatory markers. MATERIAL AND METHODS:The levels of high-sensitive C-reactive protein (hsCRP), inte...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Chazova TE,Masenko VP,Zykov KA,Golitsyna TIu

    更新日期:2007-01-01 00:00:00

  • [Pathospermia in patients with glomerulonephritis and rheumatoid arthritis treated by immunodepressants: the possibilities of its correction with zinc and parlodel].

    abstract::Two groups of patients aged 16.5-31 years with pathospermia given immunodepressants (IDS) for glomerulonephritis (group I) or rheumatoid arthritis (group II) before and/or at the moment of examination were examined. Five out of 6 patients of group I and all the patients of group II showed azoospermia. As a result of t...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kukhtevich AV,Ermolenko VM,Bunatian AF,Gitel' EP,Smirnov GA,Nosova AA,Obydena EA

    更新日期:1991-01-01 00:00:00

  • [The characteristics of cardiac diastolic function in myocardiodystrophy in persons subjected to aromatic hydrocarbon exposure].

    abstract::Left and right ventricular diastolic function was investigated at doppler echocardiography in patients with myocardiodystrophy exposed to organic aromatic solvents (30 female house painters). The control group consisted of healthy females and females with autonomic-dyshormonal myocardiodystrophy. The study group exhib...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tret'iakov SV,Loseva MI,Shpagina LA

    更新日期:1997-01-01 00:00:00

  • [State of the microcirculation and its relation to gastric function and structural changes in the gastroduodenal zone in recurrent peptic ulcer].

    abstract::A total of 108 patients with peptic ulcer were entered into the study. Examination of the microcirculation in the eye conjunctiva and microvessels of biopsy specimens of the mucous membrane taken from ulcerous areas revealed that disease relapses were marked by pronounced disorders of the end blood flow. The extent of...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Chernin VV,Mishin VI,Pavlova NI,Zotov LA

    更新日期:1986-01-01 00:00:00

  • [Biliary calculosis, cholesterosis of the gallbladder, xanthogranulematous cholecystitis: clinical-morphological parallels].

    abstract:AIM:The retrospective analysis of prevalence, peculiarities of duration of biliary calculosis without gall bladder cholesterosis, biliary calculosis with gall-bladder cholesterosis and xanthogranulematous cholecystitis among persons who underwent cholecystectomy using clinical, instrumental and morphological data. MATE...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shcherbinina MB,Zakrevskaia EV

    更新日期:2008-01-01 00:00:00

  • [Clinical course, internal picture of the disease and pathogenic reactions in patients with bronchial asthma].

    abstract:AIM:To study clinical features of bronchial asthma (BA) associated with internal picture and nosogenic reactions. MATERIAL AND METHODS:Clinical features of BA were studied in 108 patients (38 males and 70 females, mean age 44.7 +/- 1.4 years, mean BA duration 6.6 +/- 0.76 years) treated in the clinic of the I. M. Sech...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ovcharenko SI,Smulevich AB,Drobizhev MIu,Ishchenko EN,Bevz IA

    更新日期:2001-01-01 00:00:00

  • [Comparative efficacy of different therapeutic schemes in gastropathies induced by nonsteroid anti-inflammatory drugs].

    abstract:AIM:To study efficacy of colloid bismuth subcitrate (de-nol, Yamanuchi) in therapy of gastropathies provoked by nonsteroidal anti-inflammatory drugs (NSAID). MATERIAL AND METHODS:63 patients (38 women and 25 men, mean age 54.2 +/- 12.8 years) with rheumatoid arthritis (n = 14), osteoarthrosis (n = 47), gouty arthritis...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Maev IV,V'iuchnova ES,Staseva IV

    更新日期:2004-01-01 00:00:00

  • [Long-term efficacy and safety of chondroitin sulphate (structum, France) in patients with coxarthrosis].

    abstract:AIM:To evaluate long-term therapeutic effect and safety of structum in patients with manifest coxarthrosis. MATERIAL AND METHODS:Twenty patients with manifest coxarthrosis of degree I-III were given a 6 month structum course. Criteria of efficacy were Leken index, pain in the affected joints, nonsteroid anti-inflammat...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shmidt EI,Bilinskaia MA,Belozerova IV,Soldatov DG,Dmitrieva ME

    更新日期:2007-01-01 00:00:00

  • [The kallikrein-kinin system of the blood and protease-protease inhibitor balance in active sarcoidosis].

    abstract::The status of the blood kinin system, activity of serum inhibitors of proteinases (alpha 1-protease inhibitor and alpha 2-macroglobulin) as well as indices of activity of trypsin-like proteinases, elastolytic and fibrinolytic activity, free antitryptic activity and complete content of acid stable inhibitors were studi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kaminskaia GO,Balta NG,Zhukova NL,Stepanian IE,Lovacheva OV

    更新日期:1988-01-01 00:00:00

  • [Acute intestinal infections of virus etiology in adults].

    abstract:AIM:To describe clinical symptoms of sporadic cases of noro- and astroviral infection in adults; to compare a clinical picture and a course of rotaviral infection (R VI), noroviral infection (NVI) and astroviral infection (A VI). MATERIAL AND METHODS:Reverse transcription and polymerase chain reaction (RT-PCR) method ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Sagalova OI,Podkolzin AT,Abramycheva NIu,Pishchulova OA,Maleev VV

    更新日期:2006-01-01 00:00:00

  • [Causes of death in patients with rheumatic diseases in Moscow].

    abstract:AIM:To study causes of death of rheumatic patients in Moscow. MATERIAL AND METHODS:Autopsy protocols for 1999-2002 were analysed for two pathoanatomic departments of Moscow. RESULTS:Rheumatic diseases were detected in 165 cases (2.0% of overall number of autopsies in these departments). Rheumatic heart disease (RHD) ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Demina AB,Radenska-Lopovok SG,Folomeeva OM,Erdes Sh

    更新日期:2005-01-01 00:00:00

  • Treatment of gastroparesis with botulinum toxin in patient after allogenic bone marrow  transplantation.

    abstract::The case report of botulinum toxin treatment of gastroparesis in a patient following allogenic bone marrow transplantation is described. The causes of gastroparesis and methods of prevention and treatment are discussed. It was noted that pyloric injection of botulinum toxin can improve symptoms and gastric emptying. ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890160-64

    authors: Galstyan GM,Pashkova MV,Popova OY,Makarova PM,Dubnyak DS,Kuzmina LA,Parovichnikova EN

    更新日期:2018-02-14 00:00:00

  • [Chronic viral infection in patients with alcoholic liver involvement].

    abstract:AIM:Detection of viral hepatitides markers in patients with alcoholic damage to the liver. MATERIALS AND METHODS:Virological, immunological and histochemical tests were performed in 36 chronic alcoholics who had enlarged liver and/or abnormal hepatic characteristics. RESULTS:60% of the examinees carried chronic HBV, ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nikitin IG,Storozhakov GI,Volynkina VM,Uskov IuI,Kisliakov VA,Shilo VIu

    更新日期:1998-01-01 00:00:00

  • [Status of cellular immunity in diabetic microangiopathy detected by skin biopsy].

    abstract::As compared with normal persons, in 46 patients with diabetes mellitus there was a significant decrease in spontaneous leukocyte migration, a reduction in the absolute count of T-, B- and O-lymphocytes, and a rise in the relative count of D-lymphocytes. The disorders of cell-mediated immunity are formed during the fir...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ermakova NG,Saltykov BB,Velikov VK,Shubina OI,Frolova AI

    更新日期:1986-01-01 00:00:00

  • [Predictors of the efficacy of psychorelaxation therapy in hypertension].

    abstract::Results of clinical, psychological and psychophysiological examinations of 136 patients with mild essential hypertension indicate that psychorelaxation therapy is more effective in patients with a higher level of BP response to emotional stress and a shorter period of BP recovery after stress. Those patients had a mod...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Aĭvazian TA,Zaĭtsev VP

    更新日期:1991-01-01 00:00:00