Abstract：
:Development of resistance to chloroquine in rodent malaria is inhibited by giving this compound together with a potentiating mixture of pyrimethamine and sulfadoxine but this does not prevent the development of resistance to the last two compounds. The use of drug mixtures should be explored as a means of "protecting" chloroquine or new blood schizontocides intended for mass chemotherapy against human malaria. However, no general rule can be laid down without testing specific drug mixtures in long-term experiments in a suitable model such as rodent malaria.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Peters Wsubject
Has Abstractpub_date
1974-01-01 00:00:00pages
379-83issue
4eissn
0042-9686issn
1564-0604journal_volume
51pub_type
杂志文章abstract：:An influenzavirus of swine origin (swine/Taiwan/7310/70) antigenically closely related to the human A/Hong Kong/68 virus readily infected human volunteers. Those infected developed antihaemagglutinin and antineuraminidase antibodies to the human A/Hong Kong/68 virus as well as to the swine/Taiwan virus. The clinical r...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:There is a need to reassess the role of the trypanosomiases, both human and animal, in African ecology and economy. Withdrawal of control services from the Congo basin was followed by a resurgence of infection from ancient foci, many of them thought to have been extinguished. Successful elimination of Glossina in sava...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1969-01-01 00:00:00
abstract：:Poxvirus antisera adsorbed with "homologous" and "heterologous" poxvirus-infected chorioallantoic membranes (CAM) were differentiated by solid-phase radioimmunoassay (RIA). Mixtures of the antiserum dilutions and infected CAM were added directly (without centrifugation) to poxvirus-infected CAM antigens affixed to wel...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Concentration of infected erythrocytes was achieved in cell suspensions derived from long-term culture of Plasmodium falciparum growing asynchronously in human erythrocytes. This new procedure involves the slow centrifugation (at 33 g) of erythrocyte suspensions through 5% Ficoll solutions. Mature asexual erythrocytic...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:The development of several DDT-resistant strains of Anopheles atroparvus is described. They were selected by larval treatment only (RL), selection of larval and adult females (RLAF), and selection of adult females and males (RAFM). Their rate of DDT-resistance was measured in the larval and adult states (mainly in the...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1959-01-01 00:00:00
abstract：:A follow-up study of coronary heart disease (CHD) was carried out among adults in Delhi 3 years after an initial community-based epidemiological survey of the same population. A total of 575 of the 814 cases of CHD detected clinically and by electrocardiogram (ECG) in the initial survey took part. On re-examination of...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The distribution and epidemiology of parasitic diseases in both urban and periurban areas of endemic countries have been changing as development progresses. The following different scenarios involving Chagas disease, lymphatic filariasis, leishmaniasis and schistosomiasis are discussed: (1) infected persons entering n...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Rabbits have commonly been used for testing the blood-level duration limit of penicillin, but have proved not to be entirely suitable. Experiments reported in this paper on the use of sheep suggest that these animals can be successfully used for the testing of procaine benzylpenicillin with aluminium monostearate (PAM...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：:The recommended procedures and criteria for T-cell receptor (TCR) designations are described. The officially adopted designations are for the TCR A, B, D and G loci and for V, D, J and C segments. ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:This paper is a report on the first (serological) phase of a study organized by WHO in collaboration with the WHO International Reference Centre for Respiratory Virus Diseases other than Influenza in Bethesda, Md., USA, to define the viral etiology of severe respiratory infections in children, particularly in tropical...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1967-01-01 00:00:00
abstract：OBJECTIVE:To develop a tool for evaluating the risk that an outbreak of meningitis will occur in a particular district of the Niger after outbreaks have been reported in other, specified districts of the country. METHODS:A Bayesian network was represented by a graph composed of 38 nodes (one for each district in the N...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.11.086009
更新日期：2012-06-01 00:00:00
abstract：:Two regimens of fluid and electrolyte therapy were studied in children with severe cholera and noncholera diarrhoea. In one, lactated Ringer's solution was the sole intravenous fluid, additional water, glucose, and potassium being given by mouth. In the other, three different intravenous solutions were employed to mee...
journal_title：Bulletin of the World Health Organization
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1972-01-01 00:00:00
abstract：:Current transportation policies in mega-cities worldwide lead to major threats to health through traffic injuries, air pollution, noise, reduction in physical activities, and adverse impact on urban quality of life. In addition, a large section of the population in cities in low-income countries has to live in informa...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Simultaneously with the development of vaccines against diphtheria, the authors and their colleagues have studied the biological properties of the causative agent, Corynebacterium diphtheriae, and its role in the development of epidemics. This study has been made possible by the development of a lysotyping scheme for ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:The International Consortium in Psychiatric Epidemiology (ICPE) was established in 1998 by WHO to carry out cross-national comparative studies of the prevalences and correlates of mental disorders. This article describes the findings of ICPE surveys in seven countries in North America (Canada and USA), Latin America (...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The use of BCG vaccine in the prevention of leprosy has been one of the most important subjects of investigation in the field of leprology in the last 25 years. The action of the vaccine was for many years investigated by determining its effect on the lepromin reaction. Field studies were later considered essential to...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:There is a need for additional data on the distribution of pneumococcal serotypes in developing countries. We report the use of a coagglutination (COA) and a latex agglutination (LA) test for serotyping Streptococcus pneumoniae which were evaluated using 114 clinical isolates in Vellore, India. In tests to serotype 30...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:This report from the Tuberculosis Chemotherapy Centre, Madras, summarizes the progress over a 5-year period of 193 patients with newly diagnosed, sputum-positive pulmonary tuberculosis who were admitted to a concurrent comparison of home and sanatorium treatment for one year with isoniazid plus PAS. Previous reports h...
journal_title：Bulletin of the World Health Organization
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1966-01-01 00:00:00
abstract：:In this review of published findings on human immunodeficiency virus (HIV) infection and risk factors among female sex workers, we summarize the results of seroprevalence studies in different countries and discuss the different patterns of transmission among such workers in various geographical regions. The highest ra...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:To determine if higher fertility and lower contraceptive use among the poorer segments of society should be considered an inequality, reflecting a higher desire for large families among the poor, or an inequity, a product of the poor being prevented from achieving their desired fertility to the same degree as...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.06.033829
更新日期：2007-02-01 00:00:00
abstract：:In vitro studies have shown that exogenously supplied amino acids are transferred into the malaria-infected cell, where they are incorporated into proteins. Most amino acids appear to enter the cell by facilitated or simple diffusion; however, the high distribution ratios seen in Plasmodium knowlesi-infected cells are...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1977-01-01 00:00:00
abstract：:This identification key has been prepared to enable field workers in eastern and centra Africa to identify the species and subspecies of snails acting as intermediate hosts of various flukes causing bilharziasis and related diseases in man and his domestic stock.The area covered by the key is eastern Africa from the S...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1962-01-01 00:00:00
abstract：:The lack of a simple and reliable test for sulfonamides has created a problem because of the increasing use of these drugs in the chemotherapy of malaria. This paper describes a modification of the Bratton-Marshall technique, for which the reagents are easily obtainable and which can be carried out in simply equipped ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:This paper synthesizes the rates, barriers, and outcomes of HIV serostatus disclosure among women in developing countries. We identified 17 studies from peer-reviewed journals and international conference abstracts--15 from sub-Saharan Africa and 2 from south-east Asia--that included information on either the rates, b...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
abstract：:The immunological characteristics of 26 strains of Japanese encephalitis virus (JEV) isolated in Japan and Malaya between 1935 and 1966 have been investigated mainly by the antibody-absorption variant of the haemagglutination-inhibition test, and to a certain extent also by conventional haemagglutination-inhibition an...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1968-01-01 00:00:00
abstract：:Immunity in meningococcal diseases has been inadequately studied and, until now, most attempts at serotherapy and immunization against meningococcal meningitis have been unsuccessful. To ascertain the status of immunity among children at greatest risk of contracting the disease, 267 serum specimens from healthy childr...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Egg-yolk lecithin prepared as described in the second edition of of the WHO monograph on cardiolipin antigens was known to be satisfactory, but documentation was incomplete. In this paper, the authors discuss results of comparisons between egg-yolk lecithin and lecithin of beef-heart origin, carried out in four separa...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1955-01-01 00:00:00
abstract：:At the request of the Ministry of Health of the USSR, a controlled field trial of a polyvaccine containing typhoid, paratyphoid and dysentery antigens and a purified tetanus toxoid was undertaken in 1958. The main object of this trial, which was carried out over a 10-month period simultaneously in four localities, was...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1962-01-01 00:00:00
abstract：:The One Health concept covers the interrelationship between human, animal and environmental health and requires multistakeholder collaboration across many cultural, disciplinary, institutional and sectoral boundaries. Yet, the implementation of the One Health approach appears hampered by shortcomings in the global fra...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.17.202705
更新日期：2018-03-01 00:00:00
abstract：:The results of comparative assays have revealed considerable variation in the potencies of tetanus toxoids produced in different laboratories. Some manufacturers are able consistently to produce toxoids high in potency; others are not able to do so. While further work is required in order to correlate the animal assay...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1955-01-01 00:00:00
