Abstract：
:A prospective, randomized, double-blind, endoscopic study is described in which the efficacy of cimetidine (13 patients) is compared to that of antacids (14 patients) in the prevention of stress ulceration following severe thermal injury. Each treatment modality was equally effective in the prevention of acute gastroduodenal disease and its associated complications. Both cimetidine and antacids produced a near elimination of duodenal disease and markedly reduced the severity of gastric disease when compared to that of untreated historical controls. Lack of major side effects and ease of administration make cimetidine an attractive alternative to antacid therapy in the prophylaxis of stress-induced gastroduodenal disease in the thermally injured patient.
journal_name
Surgeryjournal_title
Surgeryauthors
McElwee HP,Sirinek KR,Levine BAsubject
Has Abstractpub_date
1979-10-01 00:00:00pages
620-6issue
4eissn
0039-6060issn
1532-7361pii
0039-6060(79)90210-1journal_volume
86pub_type
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