Tienilic acid: pharmacokinetics, salicylate interaction and creatinine secretion studies.

abstract：:Participant modelling, a behaviourally-orientated treatment technique, is an effect method of treating phobias associated with minor medical procedures or apparatus such as needles or intravenous catheters. The steps in this technique are described and two cases of severe needle phobias successfully treated with parti...

journal_title：Postgraduate medical journal

authors： Taylor CB,Ferguson JM,Wermuth BM

更新日期：1977-01-01 00:00:00

abstract：:A patient with long-standing ischaemic heart disease and severe low output congestive cardiac failure received numerous diuretics, which gradually became ineffective. Resistant oedema was treated by adding demeclocycline to the current diuretic regime of frusemide and metolazone. Diuresis resulted, oedema disappeared ...

journal_title：Postgraduate medical journal

authors： Bonser RS,Ghose RR

更新日期：1980-02-01 00:00:00

abstract：:We report the case of a 66 year old woman with clinical manifestations of giant-cell arteritis, positive temporal artery biopsy and excellent response to prednisone, who developed massive cerebral infarcts after 5 days of treatment. Computed tomographic and magnetic resonance imaging scans revealed multiple infarcts i...

journal_title：Postgraduate medical journal

authors： Collazos J,García-Moncó C,Martín A,Rodriguez J,Gómez MA

更新日期：1994-03-01 00:00:00

abstract：:A 19-year-old girl developed generalised anhidrosis following typhoid fever. Elaborate investigations disclosed nothing abnormal. A skin biopsy revealed the presence of atrophic as well as normal eccrine glands. This appears to be the third case of its kind in the English literature. It is postulated that typhoid feve...

journal_title：Postgraduate medical journal

authors： Raveenthiran V

更新日期：1995-07-01 00:00:00

abstract：:The occurrence of ketoacidosis in out-patient diabetics treated with continuous subcutaneous insulin infusion (CSII) has received little attention. We report two such cases of ketosis, each precipitated by infection and occurring in patients previously well controlled on CSII. This report illustrates that the risk of ...

journal_title：Postgraduate medical journal

authors： Boulton AJ,Knight G,Drury J,Ward JD

更新日期：1983-07-01 00:00:00

abstract：:Prolonged coma resulting from hypoxic brain injury is usually associated with a dismal chance of return to independent existence. In this report a case is described of a 60 year old man who recovered and returned to work as a university professor after being in a vegetative state at least 8 weeks after a prolonged cer...

journal_title：Postgraduate medical journal

authors： Falk RH

更新日期：1990-05-01 00:00:00

abstract：:Although recognized since the 1930s, slow infections have only recently received considerable attention. There are three types, group A (related to the type C RNA viruses), group B (bizarre agents such as scrapie and kuru) and group C (viruses such as measles which normally produce acute infections but which are behav...

journal_title：Postgraduate medical journal

authors： Sutton RN

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Repetitive laboratory testing in stable patients is low-value care. Electronic health record (EHR)-based interventions are easy to disseminate but can be restrictive. OBJECTIVE:To evaluate the effect of a minimally restrictive EHR-based intervention on utilisation. SETTING:One year before and after interve...

journal_title：Postgraduate medical journal

authors： Chin KK,Krishnamurthy A,Zubair T,Ramaswamy T,Hom J,Maggio P,Shieh L

更新日期：2021-02-01 00:00:00

abstract：:Focused assessment with sonography in trauma (FAST) is a limited ultrasound scan performed in the emergency department to assess patients admitted with blunt abdominal trauma (BAT). It is normally undertaken by emergency physicians in order to identify the presence of free fluid, which may represent haemoperitoneum. T...

journal_title：Postgraduate medical journal

authors： Smith J

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Previous research has shown that sicker patients are less satisfied with their healthcare, but specific effects of adverse health outcomes have not been investigated. The present study aimed to assess whether patients who experience adverse outcomes, in hospital or after discharge, differ in their evaluation...

journal_title：Postgraduate medical journal

authors： Marang-van de Mheen PJ,van Duijn-Bakker N,Kievit J

更新日期：2008-02-01 00:00:00

abstract：:The Chancellor of the Exchequer's recent announcements to devolve decision making power from Whitehall to 30 English regions provide a challenge to use devolution to deliver more favourable health outcomes. However evaluation of devolved health models internationally is scarce, because it is rarely considered. Evidenc...

journal_title：Postgraduate medical journal

authors： Doyle Y,Johnstone P

更新日期：2016-05-01 00:00:00

abstract：:The aortic root links the left ventricle and ascending aorta and functions as a support structure for the aortic valve. It can be affected by a variety of congenital and acquired conditions, some of which are potentially life threatening. Echocardiography and cardiac magnetic resonance imaging are established non-inva...

journal_title：Postgraduate medical journal

authors： Vargas HA,Hoey ET,Gopalan D,Agrawal SK,Screaton NJ,Gulati GS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Postgraduate medical education bodies and national patient safety institutes recommend that trainees develop patient safety competencies such as those for Morbidity and Mortality (M&M) rounds, yet there exists no model for their educational delivery. OBJECTIVE:We studied the effect of a single educational i...

journal_title：Postgraduate medical journal

authors： Mondoux SE,Frank JR,Kwok ESH,Cwinn AA,Lee AC,Calder LA

更新日期：2016-11-01 00:00:00

abstract：:Pneumoconiosis is still a health problem in Turkey and has a relatively high incidence. Retired underground miners were investigated to document alveolitis, and to observe the difference in the cellular profiles of bronchoalveolar lavage (BAL) fluid with or without pneumoconiosis. Twenty nine retired male miners and 1...

journal_title：Postgraduate medical journal

authors： Kayacan O,Beder S,Karnak D

更新日期：2003-09-01 00:00:00

abstract：:A 72 year old man developed acute myeloblastic leukaemia two years after he had been treated with local curative therapy and chemotherapy for a solitary plasma cytoma of the ilium. ...

journal_title：Postgraduate medical journal

authors： Maharaj D,Dolan G

更新日期：1986-12-01 00:00:00

abstract：CONTEXT:In Sweden, patient malpractice claims are handled administratively and compensated if an independent physician review confirms patient injury resulting from medical error. Full access to all malpractice claims and hospital discharge data for the country provided a unique opportunity to assess the validity of pa...

journal_title：Postgraduate medical journal

authors： Pukk-Härenstam K,Ask J,Brommels M,Thor J,Penaloza RV,Gaffney FA

更新日期：2009-02-01 00:00:00

abstract：:A case of post-thyroidectomy hypothyroidism is reported. The patient became euthyroid in three consecutive pregnancies, reverting to hypothyroid within three months of delivery on each occasion. The alteration in thyroid status is attributed to pregnancy related changes in antibody titres, though the laboratory data t...

journal_title：Postgraduate medical journal

authors： Shankar P,Kilvert A,Fox C

更新日期：2001-09-01 00:00:00

abstract：:This review considers some of the more common problems in the interpretation of the results of biochemical tests and, where possible, highlights ways in which errors can be identified or avoided. ...

journal_title：Postgraduate medical journal

authors： Ayling RM

更新日期：2000-03-01 00:00:00

abstract：:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

journal_title：Postgraduate medical journal

authors： Chan NN,Isaacs AJ

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To identify the consultation activities of clinical ethics committees (CECs) in the UK and the views of CEC chairpersons regarding such activities. METHODS:An anonymous, password-protected online questionnaire was sent by e-mail to 70 CEC chairpersons. The questionnaire contained 14 items. RESULTS:Of the 70...

journal_title：Postgraduate medical journal

authors： Whitehead JM,Sokol DK,Bowman D,Sedgwick P

更新日期：2009-09-01 00:00:00

abstract：:Ultrasound guidance has been reported to facilitate the performance of lumbar punctures (LPs). However, the use of ultrasound guidance has not yet received consistent conclusions. We performed a systematic review and meta-analysis to determine the efficacy of ultrasound-guided LPs. PubMed, Embase and the Cochrane Libr...

journal_title：Postgraduate medical journal

authors： Shu L,Huang J,Liu JC

更新日期：2021-01-01 00:00:00

abstract：:Primary gastric lymphoma is a rare tumour. It is thought that low grade gastric mucosa associated lymphoid tissue lymphoma has not been previously reported to occur in a patient with gastrojejunostomy. This report describes such a case. The patient presented with bleeding from non-healing stomal ulcers. The ulcers hea...

journal_title：Postgraduate medical journal

authors： Misra SP,Misra V,Dwivedi M

更新日期：2005-02-01 00:00:00

abstract：:The development of clinical governance in New Zealand has been pivotal to the country's health policy since 2009. Some of the key findings from one component of a national assessment project, which involved interviews with health professionals and managers at 19 of the country's 20 district health boards, are reviewed...

journal_title：Postgraduate medical journal

authors： Gauld R

更新日期：2014-01-01 00:00:00

abstract：:Purtscher's retinopathy presents to the clinician as loss of vision in a patient with a history of a possible precipitating event such as recent major trauma, pancreatitis, childbirth or renal failure. The ophthalmological picture is one of ischaemia at the posterior pole with white patches of oedema and haemorrhages ...

journal_title：Postgraduate medical journal

authors： Buckley SA,James B

更新日期：1996-07-01 00:00:00

abstract：:A case of hypereosinophilic syndrome is reported. Investigation failed to reveal any precipitating cause or evidence of leukaemia. Death was due to intractable cardiac failure, and post-mortem examination showed infiltration of the myocardium with sheets of immature cells. The relevance of these cells is discussed and...

journal_title：Postgraduate medical journal

authors： Scott DG,Leatherdale BA

更新日期：1979-01-01 00:00:00

abstract：:A 46 year old Nigerian man presented with a four week history of progressive bilateral visual loss. He had been unwell, with weight loss, fever, and night sweats for six months. Dilated fundoscopy revealed macular haemorrhages and diffuse Roth's spots. The patient was found to be severely anaemic and a bone marrow asp...

journal_title：Postgraduate medical journal

authors： Vose MJ,Charles SJ

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of, and implement a diagnostic strategy for, imported helminth infection in the gastroenterology clinic. DESIGN:A retrospective study of eosinophil count and probable tropical exposure (phase I) followed by a prospective study of parasitological investigation (phase II). SETTING:G...

journal_title：Postgraduate medical journal

authors： Smith PJ,Theis B,McCartney S,Brown M

更新日期：2012-01-01 00:00:00

abstract：:The anti-hypertensive effect of 250 mg tienilic acid was comparable to that of 50 mg hydrochlorothiazide. Unlike hydrochlorothiazide, tienilic acid caused a statistically significant decrease in the serum uric acid values. Clinically non-significant rises in blood urea nitrogen and serum creatinine occurred with both ...

journal_title：Postgraduate medical journal

authors： McMahon FG,Ryan JR,Jain AK

更新日期：1979-01-01 00:00:00

abstract：:Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary d...

journal_title：Postgraduate medical journal

authors： Lozewicz S,Morris G,Garbett N,Browse N,Slavin B,Cole P

更新日期：1988-01-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is common and may progress to cirrhosis and its complications. The pathogenesis of steatosis and cellular injury is thought to be related mostly to insulin resistance and oxidative stress. Therefore, management entails identification and treatment of metabolic risk factors, im...

journal_title：Postgraduate medical journal

authors： Adams LA,Angulo P

更新日期：2006-05-01 00:00:00