Iron absorption from human milk, simulated human milk, and proprietary formulas.

Abstract:

:Studies from our laboratory have shown that iron is better absorbed from human milk than from cow milk and that human milk can provide insufficient iron for infants during their first year. We compared iron availability from human milk with that from other formulas and determined the factors responsible for its superiority. Adults were fed 100 ml of human milk, simulated human milk, simulated human milk containing added lactoferrin, two commercial formulas containing iron, 12 mg/qt, and human milk that had been boiled. The simulated human milk resembled human milk in concentration of protein, fat, carbohydrate, iron, total minerals, calcium, and phosphorus. Iron 59 was added to each feeding and iron incorporation into RBCs was determined 14 days after each feeding. Percent iron absorption was highest from human milk and lowest from the commercial formulas. The simulated human milk supported a 9.0% absorption; addition of lactoferrin reduced this to 4.7%. Net iron absorption was 0.12 mg/liter from human milk and 0.40 and 0.37 mg/liter from the iron-enriched commercial formulas. Absorption of iron from boiled human milk was the same as from the unboiled milk. This study confirms the unique ability of human milk to promote iron absorption. Simple manipulation of the protein, fat, lactose, calcium, phosphorus, or lactoferrin content of proprietary milk did not reproduce the iron absorption demonstrated with human milk.

journal_name

Pediatrics

journal_title

Pediatrics

authors

McMillan JA,Oski FA,Lourie G,Tomarelli RM,Landaw SA

subject

Has Abstract

pub_date

1977-12-01 00:00:00

pages

896-900

issue

6

eissn

0031-4005

issn

1098-4275

journal_volume

60

pub_type

杂志文章
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    authors: Falk RE,Cederbaum SD,Blass JP,Gibson GE,Kark RA,Carrel RE

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    doi:

    authors: Tabin R,Guignard JP,Gautier E,Dubrit M,Jeannet M,Golaz J,Moretta L

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    authors: Dorney SF,Byrne WJ,Ament ME

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  • Erythema Marginatum as an Early Symptom of Hereditary Angioedema: Case Report of 2 Newborns.

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    更新日期:2016-02-01 00:00:00

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    pub_type: 杂志文章

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  • Early Intervention, Parent Talk, and Pragmatic Language in Children With Hearing Loss.

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    pub_type: 杂志文章

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    authors: Mickell JJ,Reigel DH,Cook DR,Binda RE,Safar P

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-0117

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    更新日期:2008-05-01 00:00:00

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    authors: Goodman E,Whitaker RC

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  • Pediatric generalized joint hypermobility with and without musculoskeletal complaints: a localized or systemic disorder?

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    authors: Engelbert RH,Bank RA,Sakkers RJ,Helders PJ,Beemer FA,Uiterwaal CS

    更新日期:2003-03-01 00:00:00

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1146

    authors: Khoshoo V,Edell D,Thompson A,Rubin M

    更新日期:2007-11-01 00:00:00

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    更新日期:1993-05-01 00:00:00

  • Identifying Child Abuse Fatalities During Infancy.

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