Familial amyloidosis with polyneuropathy. Aspects of the relationship between gastrointestinal symptoms, EMG findings, and malabsorption studies.

Abstract:

:Fifty-two patients with a confirmed diagnosis of familial amyloidosis with polyneuropathy living in northern Sweden were investigated. Gastrointestinal symptoms, mainly in the form of changed bowel habits, were found in 47 patients. Symptoms of polyneuropathy of the peripheral nerves usually preceded the gastrointestinal symptoms, but in 12 patients gastrointestinal dysfunction started either before or simultaneously with the neurological symptoms. Steatorrhea was found in 30 patients (58%) and an impaired D-xylose absorption in 52%. Diarrhea, anal incontinence, and a high degree of peripheral denervation indicating a severer disease were related to the presence of steatorrhea. The results of oral lactose and glucose tolerance tests were essentially normal. The results suggest that the main reason for the gastrointestinal dysfunction is a disruption of the gut autonomic nervous system rather than a barrier to the absorption of nutrients across the intestinal wall.

journal_name

Scand J Gastroenterol

authors

Steen LE,Ek BO

subject

Has Abstract

pub_date

1984-06-01 00:00:00

pages

480-6

issue

4

eissn

0036-5521

issn

1502-7708

journal_volume

19

pub_type

杂志文章
  • Diet restriction increases ubiquinone contents and inhibits progression of hepatocellular carcinoma in the rat.

    abstract:BACKGROUND:The aim of the present study was to evaluate the effect of a moderate diet restriction on the progression of preneoplastic foci into hepatocellular carcinomas (HCCs) and whether such an effect was related to altered cell proliferation, apoptosis, and/or tumour contents of lipid-soluble antioxidants. METHODS...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655200750024588

    authors: Wang GS,Olsson JM,Eriksson LC,Stål P

    更新日期:2000-01-01 00:00:00

  • Pancreatic polypeptide secretion before and after gastric bypass surgery for morbid obesity.

    abstract::Basal, meal-stimulated, and insulin-stimulated secretion of pancreatic polypeptide (PP) has been measured before and 3 and 12 months after gastric bypass surgery in 10 obese patients. The basal serum concentration of PP was significantly reduced after the operation. After a meal there was a significant increase in PP ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528109181020

    authors: Schrumpf E,Linnestad P,Nygaard K,Giercksky KE,Fausa O

    更新日期:1981-01-01 00:00:00

  • Hyperplastic manifestations of enterochromaffin-like cells in the stomach of rats with congenital moderate hypergastrinemia.

    abstract::The effect of moderate congenital hypergastrinemia on the enterochromaffin-like (ECL) cells was investigated in Zucker rats 4 and 18 months of age by combining autoradiography after tritiated thymidine injection and selective immunocytochemistry. In both age groups the serum gastrin concentration was 200% higher in ob...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529409090467

    authors: Tielemans Y,Håkanson R,Willems G

    更新日期:1994-03-01 00:00:00

  • Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapies.

    abstract::Primary sclerosing cholangitis (PSC) is a chronic, fibroinflammatory, cholestatic liver disease of unknown etiopathogenesis. PSC generally progresses to liver cirrhosis, is a major risk factor for hepatobiliary and colonic neoplasia, and confers a median survival to death or liver transplantation of only 12 years. Alt...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3109/00365521.2014.913189

    authors: Tabibian JH,O'Hara SP,Lindor KD

    更新日期:2014-08-01 00:00:00

  • Campylobacter pylori in peptic ulcer disease. III. Symptoms and paraclinical and epidemiologic findings.

    abstract::Only a few publications have dealt with the subjective symptoms, the paraclinical findings, or the epidemiology in relation to cultivation of C. pylori. Seventy-two patients answered a questionnaire containing questions about symptoms, dietary habits, smoking, and animal contact. C. pylori was cultivated from the biop...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809093877

    authors: Andersen LP,Elsborg L,Justesen T

    更新日期:1988-04-01 00:00:00

  • Modulation of arachidonic acid metabolism by olsalazine and other aminosalicylates in leukocytes.

    abstract::We investigated the action of the new aminosalicylate olsalazine (disodium azodisalicylate) on arachidonic acid metabolism in comparison with 5-aminosalicylic acid (5-ASA) and sulphasalazine (SASP) by in vitro incubation of cellular homogenates from human polymorphonuclear (PMNL) and mononuclear (MNL) leukocytes with ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529109037024

    authors: Horn H,Preclik G,Stange EF,Ditschuneit H

    更新日期:1991-08-01 00:00:00

  • 1- and 4-week cimetidine treatment for duodenal ulcer.

    abstract::Forty-eight patients with symptomatic duodenal ulcer were randomized to 4 weeks' treatment with cimetidine, 1 g/day (C4), or 1 week of cimetidine treatment followed by 3 weeks of placebo (C1 + P). The study was performed double blind. The symptoms were recorded daily on a visual analogue scale. Endoscopy was performed...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528609011103

    authors: Johannessen T,Kristensen P,Fjøsne U,Hafstad PE,Kleveland PM,Løge I,Sandbakken P,Petersen H

    更新日期:1986-08-01 00:00:00

  • Reproducibility of ambulatory gastric pH recordings in the corpus and antrum. Effect of food, time, and electrode position.

    abstract::The reproducibility of simultaneous, long-term, ambulatory gastric pH recordings in the antrum and corpus was investigated in nine healthy subjects who underwent three separate, 27-h gastric double pH-metries. Intraindividual reproducibility for the entire 27-h recording period was good in the corpus (Kendall's concor...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529008997637

    authors: Cilluffo T,Armstrong D,Castiglione F,Emde C,Galeazzi R,Gonvers JJ,Blum AL

    更新日期:1990-10-01 00:00:00

  • Recombinant human transforming growth factor beta 3 accelerates gastric ulcer healing in rats.

    abstract:BACKGROUND:Gastric ulcer healing is mediated by various endogenous growth factors. In this experimental study effect of locally and systemically applied recombinant human transforming growth factor beta 3 (rhTGF-beta 3) on gastric ulcer healing was investigated in the rat. METHODS AND RESULTS:Gastric ulcers were induc...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529709011214

    authors: Coerper S,Sigloch E,Cox D,Starlinger M,Köveker G,Becker HD

    更新日期:1997-10-01 00:00:00

  • Indomethacin-induced lesion modifies contractile activity in rat small intestines.

    abstract:BACKGROUND:Indomethacin induces intestinal lesions. The change in contractility of segments with lesions was studied. METHODS:Motility was recorded in segments with lesions isolated from the rat small intestine 24 h after a subcutaneous injection of indomethacin (20 mg/kg). RESULTS:Concentration-contraction curves fo...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529509093305

    authors: Lu YF,Mizutani M,Neya T,Nakayama S

    更新日期:1995-05-01 00:00:00

  • The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma.

    abstract:OBJECTIVE:The lack of novel therapeutic targets poses the major challenge to prolong survival and improve the quality of life for esophageal squamous cell carcinoma (ESCC). Methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) plays critical roles in folate cycle maintenance. However, little information is available...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1407440

    authors: Yang YS,Yuan Y,Hu WP,Shang QX,Chen LQ

    更新日期:2018-05-01 00:00:00

  • The role of "watch and wait" in intestinal follicular lymphoma in rituximab era.

    abstract:OBJECTIVE:There is no consensus regarding the best treatment for intestinal follicular lymphoma (FL). We used "watch and wait" for patients with intestinal FL with low-tumor-burden (LTB) criteria and without mass formation causing bowel obstruction. We investigated the overall survival (OS) and time to treatment requir...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2015.1087589

    authors: Tari A,Asaoku H,Takata K,Fujimori S,Tanaka S,Fujihara M,Koga T,Yoshino T

    更新日期:2016-03-01 00:00:00

  • Differences in the intrinsic capacity of peripheral blood mononuclear cells to produce tumor necrosis factor alpha and beta in patients with inflammatory bowel disease and healthy controls.

    abstract:BACKGROUND:Tumor necrosis factor alpha (TNF alpha) and beta (TNF beta) appear to play an important role in the regulation of the inflammatory response. The aim of the present study was to investigate the intrinsic capacity of peripheral blood mononuclear cells (PBMC) to produce these cytokines. METHODS:PBMC from 41 pa...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529509101613

    authors: Bouma G,Oudkerk Pool M,Scharenberg JG,Kolkman JJ,von Blomberg BM,Scheper RJ,Meuwissen SG,Peña AS

    更新日期:1995-11-01 00:00:00

  • The PNPLA3 rs738409 C > G polymorphism is associated with the risk of progression to cirrhosis in NAFLD patients.

    abstract:BACKGROUND AND AIMS:The patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 C > G single nucleotide polymorphism (SNP) has been associated with steatosis and fibrosis in previous NAFLD populations in which cirrhotic patients were very poorly represented. Since not all NAFLD with fibrosis evolve to cirrhosi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2016.1161066

    authors: Vespasiani-Gentilucci U,Gallo P,Porcari A,Carotti S,Galati G,Piccioni L,De Vincentis A,Dell'Unto C,Vorini F,Morini S,Riva E,Picardi A

    更新日期:2016-08-01 00:00:00

  • Selective vitamin B12 malabsorption in adult coeliac disease. Report on three cases with associated autoimmune diseases.

    abstract::Three cases of adult coeliac disease with severe vitamin B12 deficiency not accompanied by folate or iron depletion are presented. Two of the patients had the extremely rare combination of coeliac disease and lack of intrinsic factor and autoimmune thrombocytopenic purpura. A close association between coeliac disease ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809090176

    authors: Stene-Larsen G,Mosvold J,Ly B

    更新日期:1988-11-01 00:00:00

  • Does water-perfused catheter overdiagnose anismus compared to balloon probe?

    abstract:BACKGROUND:The purpose of this study was to compare the manometric assessment of straining effort as if to defecate and rectoanal inhibitory reflex obtained with a rectosphincteric balloon probe and with a water-perfused catheter in the same subject. METHODS:Twelve healthy volunteers underwent two manometric assessmen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/003655202762671288

    authors: Savoye G,Leroi AM,Bertot-Sassigneux P,Touchais JY,Devroede G,Denis P

    更新日期:2002-12-01 00:00:00

  • Carcinoma of the pancreas and papilla of Vater: presenting symptoms, signs, and diagnosis related to stage and tumour site. A prospective multicentre trial in 472 patients. Norwegian Pancreatic Cancer Trial.

    abstract::During the period 1984-87, 472 patients with histologically or cytologically verified carcinoma of the pancreas (n = 442) or the papilla of Vater (n = 30) were accrued. Diagnostic investigations were performed in accordance with the ordinary routines of 38 Norwegian hospitals. Jaundice at presentation, found in 47% of...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3109/00365529209000081

    authors: Bakkevold KE,Arnesjø B,Kambestad B

    更新日期:1992-04-01 00:00:00

  • Anal endosonography in asymptomatic subjects.

    abstract::The anal sphincter thickness was measured ultrasonographically in 30 asymptomatic subjects (13 male and 17 female: 23 young and 7 old). The internal anal sphincter (IAS) was measured at its thickest portion in the anal canal, its borders lying between the submucosa and the external and sphincter (EAS). The EAS was mea...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529309098265

    authors: Papachrysostomou M,Pye SD,Wild SR,Smith AN

    更新日期:1993-06-01 00:00:00

  • Relations between circulating gastrin and endocrine cell proliferation in the atrophic gastric fundic mucosa.

    abstract::It has been suggested that gastrin may be a causative factor in the proliferation of gastric fundic mucosal endocrine cells, as seen in the Zollinger-Ellison syndrome and in atrophic gastritis with hypergastrinemia of antral origin. In the present study, morphometrically determined densities of endocrine cells in fund...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609003087

    authors: Borch K,Renvall H,Liedberg G,Andersen BN

    更新日期:1986-04-01 00:00:00

  • Changes in inflammatory bowel disease subtype during follow-up and over time in 44,302 patients.

    abstract:AIM:To investigate inflammatory bowel disease (IBD) register-based subtype classifications over a patient's disease course and over time. METHODS:We examined International Classification of Diseases coding in patients with ≥2 IBD diagnostic listings in the National Patient Register 2002-2014 (n = 44,302). RESULTS:18%...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1564361

    authors: Everhov ÅH,Sachs MC,Malmborg P,Nordenvall C,Myrelid P,Khalili H,Elmberg M,Ekbom A,Askling J,Jakobsson G,Halfvarson J,Ludvigsson JF,Olén O

    更新日期:2019-01-01 00:00:00

  • Pancreatic dose-response curves to cholecystokinin determined by two techniques in dogs.

    abstract::Dose-response (DR) curves for pancreatic flow rate, bicarbonate and protein output to cholecystokinin (CCK) were determined by two techniques in six conscious dogs with gastric and duodenal Thomas fistulas. With the continuous DR technique G.I.H. CCK was given by intravenous infusion in doses from 0.75 to 24 Ivy dog u...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527809181377

    authors: Singer MV,Sarles H

    更新日期:1978-01-01 00:00:00

  • Helicobacter pylori infection inhibits antral mucosal nitric oxide production in humans.

    abstract:BACKGROUND:Inducible NO synthase expression is upregulated in H. pylori-infected gastric mucosa, suggesting increased NO synthesis as part of a host defense reaction. This study investigates actual NO production in the human antrum in situ. METHODS:Gastroscopy with antral biopsy sampling and intragastric tonometric NO...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655202317316024

    authors: von Bothmer C,Edebo A,Lönroth H,Olbe L,Pettersson A,Fändriks L

    更新日期:2002-04-01 00:00:00

  • Morphometric studies of human parietal cells before and 7 days after proximal gastric vagotomy.

    abstract::In nine patients, acid titration tests and gastric biopsy specimens were studied before proximal gastric vagotomy (PGV) and 1 week after the operation. When postoperative biopsy specimens were compared with the preoperative ones, no change was found in the thickness of the mucosa. The volume fraction of the mucosa mad...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Aase S,Roland M,Liavåg I,Dahl E

    更新日期:1984-07-01 00:00:00

  • Faecal calprotectin: a novel test for the diagnosis of colorectal cancer?

    abstract::Calprotectin, a prominent cytosol protein in neutrophil granulocytes, was present in increased concentrations in stools from 50 of 53 patients with colorectal cancer, 32 of 40 patients with colorectal polyps, and all of 18 patients with gastric cancer. After radical surgery, faecal calprotectin levels reverted to the ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529309098312

    authors: Røseth AG,Kristinsson J,Fagerhol MK,Schjønsby H,Aadland E,Nygaard K,Roald B

    更新日期:1993-12-01 00:00:00

  • Non-invasive detection of low-intestinal lactase activity in children by use of a combined 13CO2/H2 breath test.

    abstract:BACKGROUND:The aim of the study was to diagnose hypolactasia with a higher accuracy than with the traditional H2 breath test. METHODS:We used a combined 13C-lactose 13CO2/H2 breath test, which was performed in 33 patients in whom lactase activity was measured. RESULTS:Lactase activity was reduced in 13 cases. The sen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365529950172808

    authors: Koetse HA,Stellaard F,Bijleveld CM,Elzinga H,Boverhof R,van der Meer R,Vonk RJ,Sauer PJ

    更新日期:1999-01-01 00:00:00

  • p21/waf1/cip1 in gastric cancer: associations with histopathological subtypes, lymphonodal metastasis, prognosis and p53 status.

    abstract:BACKGROUND:Cyclins and cyclin-dependent kinases are determining factors of the cell cycle. In the present study, we investigated the role of p21 and p53 in the biology of gastric cancer, focusing on its influence on progression and prognosis (n = 195). METHODS:P21 and p53 immunoreactivity was analysed immunohistochemi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201750305512

    authors: Baldus SE,Schneider PM,Mönig SP,Zirbes TK,Fromm S,Meyer W,Glossmann J,Schüler S,Thiele J,Hölscher AH,Dienes HP

    更新日期:2001-09-01 00:00:00

  • Nosography of X-ray negative dyspepsia.

    abstract::The clinical pictures of 109 patients with X-ray negative dyspepsia (XND) are described, and a comparison is made with the clinical pictures of 39 gastric ulcer patients and 61 duodenal ulcer patients. In addition it has been attempted to subdivide XND into clinically relevant subgroups by means of a Venn diagram. The...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Möllmann KM,Bonnevie O,Gudmand-Höyer E,Wulff HR

    更新日期:1976-01-01 00:00:00

  • Update on ischemic colitis: from etiopathology to treatment including patients of intensive care unit.

    abstract::Ischemic colitis is the result of colonic hypoperfusion and is regarded as a relatively rare condition. It can be roughly classified as occlusive and non-occlusive. Pathogenesis includes a usually transient compromise in the colonic vasculature, with a parallel activation of an inflammatory cascade caused primarily by...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3109/00365521.2016.1162325

    authors: Doulberis M,Panagopoulos P,Scherz S,Dellaporta E,Kouklakis G

    更新日期:2016-08-01 00:00:00

  • Enteroendocrine, Musashi 1 and neurogenin 3 cells in the large intestine of Thai and Norwegian patients with irritable bowel syndrome.

    abstract:OBJECTIVES:The prevalence, gender distribution and clinical presentation of IBS differ between Asian and Western countries. This study aimed at studying and comparing enteroendocrine, Musashi 1 (Msi 1) and neurogenin 3 (neurog 3) cells in Thai and Norwegian IBS patients. MATERIAL AND METHODS:Thirty Thai and 61 Norwegi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1371793

    authors: El-Salhy M,Patcharatrakul T,Hatlebakk JG,Hausken T,Gilja OH,Gonlachanvit S

    更新日期:2017-12-01 00:00:00

  • Fasting levels of serum gastrin in different functional and morphologic states of the antrofundal mucosa. An analysis of 860 subjects.

    abstract::The relationship of fasting serum gastrin (FSG) levels to the histologic state of antral and body mucosa and to the stimulated acid output (PAO) was examined in 860 subjects. The FSG levels correlated with PAO and atrophy of the body mucosa: the FSG increased linearly with an increase in the grade of body atrophy and ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529009095523

    authors: Sipponen P,Valle J,Varis K,Kekki M,Ihamäki T,Siurala M

    更新日期:1990-05-01 00:00:00