Indomethacin-induced lesion modifies contractile activity in rat small intestines.

abstract：:We investigated the electrogenic transport of glucose in the upper part of the duodenum in 11 healthy subjects by means of simultaneous intestinal perfusion of test solutions and measurement of the corresponding potential differences between blood and the duodenal lumen. The technique entailed continuous perfusion and...

journal_title：Scandinavian journal of gastroenterology

authors： Sparsø BH,Luke M,Wium E

更新日期：1984-06-01 00:00:00

abstract：:Background and aim: Acute-on-chronic liver failure (ACLF) is characterized by the presence of acute decompensation (AD) of cirrhosis, organ failures, and high short-term mortality rates. In present study, we explored whether Pro-adrenomedullin (Pro-ADM), a biomarker of sepsis, is a potential marker of outcome in patie...

journal_title：Scandinavian journal of gastroenterology

authors： Yan H,Jin S,Liang L,Du J,Aithal GP,Li L

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Gastrointestinal involvement is frequent in patients with scleroderma. Erythromycin, a macrolide antibiotic, has been shown to accelerate gastric emptying in normal subjects and diabetic patients. The present study investigated the effects of acute erythromycin administration on gastric and gallbladder motil...

journal_title：Scandinavian journal of gastroenterology

authors： Fiorucci S,Distrutti E,Bassotti G,Gerli R,Chiucchiù S,Betti C,Santucci L,Morelli A

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Interdigestive small-intestinal motility is suppressed by hyperglycemia and also by hyperinsulinemia per se. Since hyperinsulinemia may increase sympathetic activity, the present study was undertaken to ascertain to what extent insulin affects phase III of the migrating motor complex (MMC) and MMC-related du...

journal_title：Scandinavian journal of gastroenterology

authors： Björnsson ES,Urbanavicius V,Eliasson B,Attvall S,Smith U,Abrahamsson H

更新日期：1995-03-01 00:00:00

abstract：:The effect of platelet-derived growth factor-BB (PDGF-BB) was evaluated in rats with indomethacin-induced gastric lesions. Animals were treated with either saline solution or several doses of PDGF-BB given orally. Rats treated with 0.1 nmol/kg PDGF-BB showed a statistically significant reduction of gastric damage. Hig...

journal_title：Scandinavian journal of gastroenterology

authors： Guglietta A,Hervada T,Nardi RV,Lesch CA

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:The peptoid CI-988 has previously been shown to have high affinity for the cholecystokinin (CCK)-B/gastrin receptor and has been reported to be a powerful CCK antagonist in many systems, although it has agonist activity on histidine decarboxylase in the rat. METHODS:In the present study the effect of CI-988...

journal_title：Scandinavian journal of gastroenterology

authors： Marvik R,Sandvik AK,Waldum HL

更新日期：1997-06-01 00:00:00

abstract：:Intragastric pH was measured during physiological conditions over 24-h periods in patients with peptic ulcer disease. After single oral doses of 20, 40, and 80 mg omeprazole we found a dose-dependent reduction in mean intragastric acidity ranging from 38% to 99%. After treatment for 1 week with omeprazole, 40 mg daily...

journal_title：Scandinavian journal of gastroenterology

authors： Naesdal J,Bodemar G,Walan A

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Topical treatment is effective in patients with distal ulcerative colitis. This trial compares the efficacy, safety, and practicality of 4 weeks' treatment with 500 mg mesalazine suppositories with those of 178 mg hydrocortisone foam, both given twice daily. METHODS:Seventy-nine patients with distal ulcerat...

journal_title：Scandinavian journal of gastroenterology

authors： Farup PG,Hovde O,Halvorsen FA,Raknerud N,Brodin U

更新日期：1995-02-01 00:00:00

abstract：:Single doses of 10 mg or 20 mg intravenously or 25 mg or 40 mg orally of a new histamine H2-receptor antagonist, SK&F 93479, have been administered to 31 patients with peptic ulcer disease. BAO and MAO were measured before and repeated during a 26-h period after drug administration. In a separate group of 17 patients ...

journal_title：Scandinavian journal of gastroenterology

authors： Jönsson KA,Bodemar G,Norlander B,Walan A

更新日期：1984-03-01 00:00:00

abstract：:In the present study the influence of duodenal exclusion and vagotomy on basal release of gastrin from extra-antral stores has been investigated in addition to the consequences of these procedures on the gastrin response to gastrin-releasing peptide (GRP) infusion. Basal gastrin concentrations and the response to GRP ...

journal_title：Scandinavian journal of gastroenterology

authors： Sjövall M,Lundell L,Rehfeld JF,Olbe L

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:Pancreatic cystic lesions (PCLs) are diagnostically challenging and there are currently several different guidelines. The aim of this study was to compare diagnostic performance of the most widely utilized International Association of Pancreatology (IAP) guidelines and the recent evidence-based European guide...

journal_title：Scandinavian journal of gastroenterology

authors： Kovacevic B,Hansen MC,Kristensen TS,Karstensen JG,Klausen P,Storkholm J,Hansen CP,Vilmann P

更新日期：2020-12-01 00:00:00

abstract：:Aprotinin was found to inhibit the amplitude of electrically stimulated contractions of the isolated guinea pig ileum with an ID50 of 6.75 X 10(-6) M. Aprotinin inhibited pentagastrin-stimulated gastric acid secretion in the rat, cat, and pig after oral or intraventricular administration. No inhibition of gastric acid...

journal_title：Scandinavian journal of gastroenterology

authors： Jørgensen KD,Diamant B

更新日期：1984-11-01 00:00:00

abstract：:Omeprazole has an anti-ulcerogenic effect and protects rat gastric mucosa against drug-induced damage in vivo. We have evaluated omeprazole protection against damage induced by sodium taurocholate to gastric epithelial cell monolayers, an experimental model that completely excludes the influence of systemic factors. F...

journal_title：Scandinavian journal of gastroenterology

authors： Romano M,Razandi M,Ivey KJ

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:We wanted to investigate the influence of viral genotype on the severity of liver injury and response to interferon and whether the level of viremia differs in accordance with genotype, severity of liver disease, and response to interferon in patients with hepatitis C virus (HCV) infection. METHODS:We studi...

journal_title：Scandinavian journal of gastroenterology

authors： Fernández I,Castellano G,Domingo MJ,Fuertes A,Colina F,Canga F,de la Cruz FJ,de la Cámara AG,Solís JA

更新日期：1997-01-01 00:00:00

abstract：:Fasting plasma levels of immunoreactive gastrin, somatostatin, and pancreatic polypeptide (PP) were determined in 67 patients with an endoscopically proven duodenal, pyloric, or prepyloric ulcer. Pretreatment gastrin (45.6 +/- 53.6 pmol/l, mean +/- S.D.) and somatostatin (54.5 +/- 27.5 pg/ml) did not differ significan...

journal_title：Scandinavian journal of gastroenterology

authors： Gustavsson S,Adami HO,Björklund O,Enander LK,Lundqvist G,Lööf L,Nordahl A

更新日期：1982-01-01 00:00:00

abstract：:The aim of the present study was to evaluate interdigestive gastrointestinal motility and its coordination with plasma concentrations of motilin and pancreatic polypeptide (PP) in 14 patients with severe obesity and in 10 control subjects with normal body weight. Motor activity of the stomach, duodenum, and proximal j...

journal_title：Scandinavian journal of gastroenterology

authors： Pieramico O,Malfertheiner P,Nelson DK,Glasbrenner B,Ditschuneit H

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:Gastric cancer confined to the muscularis propria (mp) has a favorable prognosis, but still belongs to the advanced category. Many oncologists have difficulties in selecting treatment modalities owing to the confused situation of mp cancer. To clarify the therapeutic strategy, the clinicopathological characte...

journal_title：Scandinavian journal of gastroenterology

authors： Park SS,Kim CS,Mok YJ,Kim SJ,Kim HI

更新日期：2005-04-01 00:00:00

abstract：:Experiments were performed on 4 non-anaesthetized dogs with chronic gastric fistulae. Gastric tonus was studied by volume and inflow rate recording at low pressure heads. Gastric tonus was not affected by propranolol or phentolamine. It was markedly reduced by atropine, presumably by blocking excitatory cholinergic ne...

journal_title：Scandinavian journal of gastroenterology

authors： Jahnberg T,Abrahamsson H,Jansson G,Martinson J

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Since the recognition of tissue transglutaminase (tTG) as the target antigen of anti-endomysium antibodies, several ELISA assays using either guinea pig or human recombinant tTG have been developed. The aim of the study was to compare the behaviour of anti-tTG and anti-endomysium antibodies assays in coeliac...

journal_title：Scandinavian journal of gastroenterology

authors： Vecchi MD,Folli C,Donato MF,Formenti S,Arosio E,Franchis R

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the role of 8-OHdG (8-hydroxy-2'-deoxyguanosine) detecting oxidative stress response following cholecystectomy in a randomised multicentre study of patients with minilaparotomy cholecystectomy (MC) versus laparoscopic cholecystectomy (LC). METHODS:Initially, 106 patients ...

journal_title：Scandinavian journal of gastroenterology

authors： Aspinen S,Harju J,Juvonen P,Selander T,Kokki H,Pulkki K,Eskelinen MJ

更新日期：2016-12-01 00:00:00

abstract：:Biopsy specimens from the antral and body part of the stomach were studied for a range of marker enzymes in 11 patients with superficial gastritis, 9 patients with atrophic gastritis, and 31 Billroth-II-resected patients and compared with activities found in controls with normal gastric mucosa. In the antral part of t...

journal_title：Scandinavian journal of gastroenterology

authors： Odegaard S,Børkje B,Skagen DW,Laerum OD,Schrumpf E

更新日期：1986-12-01 00:00:00

abstract：:The diagnostic value of barium meal and endoscopy for the diagnosis of gastric ulcer and cancer was studied in 173 unselected patients with upper abdominal dyspepsia. The predictive value of both positive and negative results was higher for endoscopy than for barium meal. This was also found in earlier studies compris...

journal_title：Scandinavian journal of gastroenterology

authors： Kiil J,Andersen D

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Stimulation of gastric motility has been supposed to accelerate the healing of gastric ulcer. The combination of the prokinetic drug cisapride and the H2 blocker ranitidine was tested in the treatment of uncomplicated gastric ulcer. METHODS:Cisapride, 20 mg twice daily (Cis), and ranitidine, 150 mg twice da...

journal_title：Scandinavian journal of gastroenterology

authors： Stubberöd A,Glise H,Hallerbäck B,Solhaug JH

更新日期：1995-02-01 00:00:00

abstract：:Two screenings with Hemoccult-II were performed in a randomized study, allocating 30,970 persons to screening and 30,968 as controls in a population of 140,000 between 45 and 74 years old on the island of Funen, Denmark. The test was completed in 20,672 initially and in 18,779 of these during rescreening 2 years later...

journal_title：Scandinavian journal of gastroenterology

authors： Kronborg O,Fenger C,Olsen J,Bech K,Søndergaard O

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Hepatic stimulator substance (HSS) is a known hepatic growth factor that appears to be organ-specific but species-nonspecific. In the present study we investigated the effect of HSS administration in a rat model of liver injury and regeneration induced by thioacetamide (TAA) injection. METHODS:TAA (300 mg/k...

journal_title：Scandinavian journal of gastroenterology

authors： Theocharis SE,Margeli AP,Agapitos EV,Mykoniatis MG,Kittas CN,Davaris PS

更新日期：1998-06-01 00:00:00

abstract：:During the period 1984-87, 472 patients with histologically or cytologically verified carcinoma of the pancreas (n = 442) or the papilla of Vater (n = 30) were accrued. Diagnostic investigations were performed in accordance with the ordinary routines of 38 Norwegian hospitals. Jaundice at presentation, found in 47% of...

journal_title：Scandinavian journal of gastroenterology

authors： Bakkevold KE,Arnesjø B,Kambestad B

更新日期：1992-04-01 00:00:00

abstract：:Forty-eight patients with symptomatic duodenal ulcer were randomized to 4 weeks' treatment with cimetidine, 1 g/day (C4), or 1 week of cimetidine treatment followed by 3 weeks of placebo (C1 + P). The study was performed double blind. The symptoms were recorded daily on a visual analogue scale. Endoscopy was performed...

journal_title：Scandinavian journal of gastroenterology

authors： Johannessen T,Kristensen P,Fjøsne U,Hafstad PE,Kleveland PM,Løge I,Sandbakken P,Petersen H

更新日期：1986-08-01 00:00:00

abstract：OBJECTIVES:To compare cumulative ionizing radiation in patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) for the years 2001-2011. To study how radiation exposure change over time in patients with newly diagnosed IBD and factors associated with radiation exposure. MATERIAL AND METHODS:Al...

journal_title：Scandinavian journal of gastroenterology

authors： Englund H,Lidén K K,Lind T,Sundström T,Karling P

更新日期：2017-03-01 00:00:00

abstract：:To ascertain whether any of the well-known effects of intravenous ethanol on pancreatic and gastric secretion could be due to its metabolite--acetaldehyde, a strong cytotoxic and sympathomimetic agent--acetaldehyde was given intravenously for 1 h (50, 100, and 200 mg/kg/h) in seven dogs. Acetaldehyde did not modify pa...

journal_title：Scandinavian journal of gastroenterology

authors： Andersen BN,Demol P,Treffot MJ,Sarles H

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Colonic permeability was studied in vitro in patients subjected to colectomy because of ulcerative colitis and in control patients undergoing colonic resections for cancer. METHODS:The mucosal layer from fresh colonic segments was stripped and mounted in Ussing diffusion chambers containing modified Krebs b...

journal_title：Scandinavian journal of gastroenterology

authors： Nejdfors P,Wang Q,Ekelund M,Weström BR,Jansson O,Lindström CL,Karlsson B,Jeppsson B

更新日期：1998-07-01 00:00:00