Abstract:
OBJECTIVE:Determining the adherence to ACC/AHA/ESC 2006 guidelines and its influence on the survival of patients with atrial fibrillation. METHODS:Prospective observational study of patients discharged during 2007 from an Internal Medicine department with a main or secondary diagnose of atrial fibrillation. The stroke risk was estimated with the CHADS2 score. The follow-up was carried out in outpatient medical office or via telephone. RESULTS:We included 259 patients (mean age 80.9 years); 73% of them had a high risk of stroke. Oral anticoagulants were administered to 134 (51.7%), and antiplatelet drugs to 71 (27%) patients. A rate control strategy was chosen for 155 (59.8%) patients and a rhythm control one for 28 (10.8%). In 100 (38.6%) patients, treatment was adherent to the guidelines. Adherence to the guidelines was associated with age (0.95 95%CI 0.92-0.99; p=0.03), contraindication to the use of oral anticoagulants (0.38 95%CI 0.18-0.81; p=0.01) and mitral valve heart disease/valvular prosthesis (2.10 95%CI 1.04-4.25; p=0.04). The median follow-up was 727 days, and 191 patients died. Patients treated according to the guidelines had a higher rate of survival during the first three years (0.47 vs. 0.36; p=0.049). The use of oral anticoagulants was associated with a higher probability of survival over a 5 year period (0.34 vs 0.21; p=0.001) and the rate control strategy during the first year (0.69 vs 0.57; p=0.04). CONCLUSIONS:In the real world, the treatment of atrial fibrillation according to the guidelines is associated with improved survival for up to three years during follow-up.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Díez-Manglano J,Gomes-Martín J,Al-Cheikh-Felices P,Pérez SI,Díez-Angulo R,Clemente-Sarasa Cdoi
10.1016/j.ijcard.2014.07.098subject
Has Abstractpub_date
2014-09-20 00:00:00pages
430-6issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(14)01308-4journal_volume
176pub_type
杂志文章abstract:BACKGROUND:Heart failure (HF) imposes both direct costs to healthcare systems and indirect costs to society through morbidity, unpaid care costs, premature mortality and lost productivity. The global economic burden of HF is not known. METHODS:We estimated the overall cost of heart failure in 2012, in both direct and ...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,多中心研究
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journal_title:International journal of cardiology
pub_type: 信件
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析
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更新日期:2015-09-15 00:00:00
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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journal_title:International journal of cardiology
pub_type: 信件,评审
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更新日期:2009-07-24 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2008-01-24 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2015-03-15 00:00:00
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pub_type: 杂志文章
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