Quantification of the peripheral blood colony forming unit-culture rise following chemotherapy. Could leukocytaphereses replace bone marrow for autologous transplantation?

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Vitamin K is reported to begin reversing warfarin within 6 to 12 hours, but this may occur sooner. We sought to determine the rate of international normalized ratio (INR) reversal following vitamin K and relationships with dose, route, and baseline INR. METHODS:We evaluated adult patients receiving vitamin ...

journal_title：Transfusion

authors： Polito NB,Kanouse E,Jones CMC,McCann M,Refaai MA,Acquisto NM

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The platelet (PLT) Pan Genera Detection test (PGD) is a rapid bacterial detection system used to screen PLTs for bacterial contamination. We report a single center 46-month experience with secondary screening of apheresis PLTs by PGD testing. STUDY DESIGN AND METHODS:Existing testing records of apheresis PL...

journal_title：Transfusion

authors： Dunbar NM,Kreuter JD,Marx-Wood CR,Dumont LJ,Szczepiorkowski ZM

更新日期：2013-10-01 00:00:00

abstract：:This study was designed to test the viability of two multiple request techniques of behavioral influence for recruiting blood donors by telephone. The first technique utilizes a small antecedent request to encourage behavioral involvement and favorable disposition toward the target activity of the critical request to ...

journal_title：Transfusion

authors： Hayes TJ,Dwyer FR,Greenwalt TJ,Coe NA

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Mathematical models predict that, in Spain, a significant number of blood units will be obtained during the window period of the hepatitis B virus (HBV) infection. Routine nucleic acid testing (NAT) on individual blood units may provide experimental data to evaluate such a theoretical risk. STUDY DESIGN AND...

journal_title：Transfusion

authors： González R,Echevarria JM,Avellón A,Barea L,Castro E

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Transfusion of plasma is a basic treatment for complex coagulopathies as well as in major blood loss. Early transfusion of plasma after trauma with major hemorrhage has been recommended by retrospective studies. However, the use of plasma is often hampered by the need to maintain a cold chain and the time ne...

journal_title：Transfusion

authors： Bux J,Dickhörner D,Scheel E

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Transfusion-induced serum sickness reactions are rarely reported in the literature. The Type III hypersensitivity reaction to heterologous proteins involves deposition of complement and immune complexes in small vessel walls resulting in a leukocytoclastic vasculitis. A case of a multiply transfused patient ...

journal_title：Transfusion

authors： Saegeman V,Wynendaele W,Kerre S,Dedeurwaerdere F,Van den Driessche M,Moerman J

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

journal_title：Transfusion

authors： Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:In this study the applicability of a 16S rRNA real-time reverse transcriptase polymerase chain reaction (RT-PCR) and a Staphylococcus genus-specific PCR for screening of bacterial contamination in platelet concentrates (PCs) was determined. STUDY DESIGN AND METHODS:A total of 336 sample bags, from PCs that ...

journal_title：Transfusion

authors： Rood IG,Pettersson A,Savelkoul PH,de Korte D

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Exposure to blood products during pregnancy carries a potential risk of transfusion transmission of infectious agents. Blood agencies have historically sought optimal deferral and testing strategies to protect blood supplies in part to ensure the protection of pregnant women and their unborn infants. The Zik...

journal_title：Transfusion

authors： Murphy MS,Shehata N,Colas JA,Chassé M,Fergusson DA,O'Brien SF,Goldman M,Tinmouth A,Forster AJ,Wilson K

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Antibodies produced against the D antigen make use of IGHV genes restricted to the IGHV3 superfamily. These findings are based on the IGHV gene analysis in anti-D-producing B cells from hyperimmunized donors, however, and therefore the restriction might be due to the hyperimmunization. In this study the IGHV...

journal_title：Transfusion

authors： Dohmen SE,Verhagen OJ,Muit J,Ligthart PC,van der Schoot CE

更新日期：2006-12-01 00:00:00

abstract：:Alanine aminotransferase (ALT) phenotype and serum activities were determined in 200 random volunteer blood donors. Serum enzyme activities were not significantly affected by the ALT phenotype (p greater than 0.1). Studies on 500 random volunteer blood donors showed significant differences in serum ALT levels between ...

journal_title：Transfusion

authors： Savage B,Sayers MH,Giblett ER

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that can be transmitted by transfusion. The diagnosis of chronic T. cruzi infection is generally made by detecting specific antibodies that bind to parasite antigens. The aim of this study was to assess the sensitivity and specificity of a n...

journal_title：Transfusion

authors： Chang CD,Cheng KY,Jiang LX,Salbilla VA,Haller AS,Yem AW,Bryant JD,Kirchhoff LV,Leiby DA,Schochetman G,Shah DO

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:A single injection of pegfilgrastim has been shown to be equivalent to daily filgrastim in enhancing neutrophil recovery after chemotherapy, whereas the experiences with pegfilgrastim in mobilization of peripheral blood progenitor cells (PBPCs) are limited. STUDY DESIGN AND METHODS:Forty unselected patients...

journal_title：Transfusion

authors： Kroschinsky F,Hölig K,Platzbecker U,Poppe-Thiede K,Ordemann R,Blechschmidt M,Oelschlaegel U,Schaich M,Hänel M,Bornhäuser M,Ehninger G

更新日期：2006-08-01 00:00:00

abstract：:The use of the direct manual hexadimethrine bromide (Polybrene) test (DPT) in the investigation of patients for autoimmune hemolytic anemia (AIHA) was evaluated. Seventy-nine blood samples from 68 patients were tested. A direct antiglobulin test (DAT) using monospecific reagents and the DPT were performed, and a conce...

journal_title：Transfusion

authors： Owen I,Hows J

更新日期：1990-11-01 00:00:00

abstract：:Leukapheresis by continuous flow centrifugation (CFC) or filtration (FL) were compared in untreated and corticosteroid-treated donors. The administration of prednisone 60 mg orally 10 to 12 hours before leukapheresis increased significantly both the donor's prepheresis WBC counts and the total granulocyte yields by CF...

journal_title：Transfusion

authors： MacPherson JL,Nusbacher J,Bennett JM

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:Critically bleeding trauma patients require coordinated and efficient decision-making processes to ensure optimal management of their massive transfusion (MT) requirements. Human factors (HFs) is a discipline that investigates factors influencing work processes from the organizational, group, and individual ...

journal_title：Transfusion

authors： Enticott JC,Jeffcott S,Ibrahim JE,Wood EM,Cole-Sinclair M,Fitzgerald M,Cameron PA,Phillips LE

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Extreme leukocytosis, generally defined as a white blood cell (WBC) count of more than 100 × 10(9) /L consisting largely of blast cells, especially when accompanied by clinical signs and symptoms of leukostasis or hyperviscosity, often predicts a poor clinical outcome in patients with acute leukemia. In this...

journal_title：Transfusion

authors： Kurnaz F,Sivgin S,Pala C,Yildirim R,Baldane S,Kaynar L,Solmaz M,Ozturk A,Eser B,Cetin M,Unal A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

journal_title：Transfusion

authors： Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

更新日期：2016-05-01 00:00:00

abstract：:As the number of successful marrow transplants has increased, the lack of HLA-identical sibling donors for 60 to 70 percent of transplant candidates has become a serious problem. Pilot studies established that marrow transplantation between phenotypically HLA-identical, unrelated individuals can be accomplished succes...

journal_title：Transfusion

authors： Stroncek D,Bartsch G,Perkins HA,Randall BL,Hansen JA,McCullough J

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Patients with thalassemia major require iron chelation therapy (ICT) to prevent complications from transfusional iron overload. Deferoxamine is effective, but requires administration as a slow continuous subcutaneous or intravenous infusion five to seven times per week. Deferiprone is a three-times-daily ora...

journal_title：Transfusion

authors： Delea TE,Edelsberg J,Sofrygin O,Thomas SK,Baladi JF,Phatak PD,Coates TD

更新日期：2007-10-01 00:00:00

abstract：:Mild-to-profound anemia, thrombocytopenia, and rarely neutropenia have been observed in patients with the acquired immune deficiency syndrome (AIDS). To investigate a possible immune mechanism, blood samples from 28 hospitalized AIDS patients, four asymptomatic homosexual men, four homosexual men with the AIDS-related...

journal_title：Transfusion

authors： McGinniss MH,Macher AM,Rook AH,Alter HJ

更新日期：1986-09-01 00:00:00

abstract：:A 27-year-old, gravida 3, para 2 woman experienced a delayed hemolytic transfusion reaction. She had anti-Dob in both serum and eluate 8 days after infusion of 6 units of Do(b+) red cells. No antibody had been detected prior to transfusion. By the 15th day after transfusion, there was no evidence of survival of red ce...

journal_title：Transfusion

authors： Moheng MC,McCarthy P,Pierce SR

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Allogeneic transfusion can result in alloimmunization, leading to platelet (PLT) refractoriness and rejection of solid organ transplants. Previously we demonstrated that pathogen reduction using UV light and riboflavin (UV + R) eliminates the immunogenicity of white blood cells (WBCs) in vitro, blocks alloim...

journal_title：Transfusion

authors： Muench MO,Heitman JW,Inglis H,Fomin ME,Marschner S,Goodrich RP,Norris PJ,Jackman RP

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Photodynamic virus inactivation of plasma with methylene blue significantly decreases the recovery of fibrinogen and coagulation factors V and VIII. Because an adequate supply of fibrinogen is essential for the therapeutic efficacy of transfused plasma in many clinical settings, it was plausible that transfu...

journal_title：Transfusion

authors： Atance R,Pereira A,Ramírez B

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Collections and transfusions of blood in the United States in 1994 were measured and compared with those in 1992. STUDY DESIGN AND METHODS:Completed survey questionnaires were returned by all 147 regional blood centers, 1340 American Association of Blood Banks (AABB) member hospitals, and 523 non-AABB hospi...

journal_title：Transfusion

authors： Wallace EL,Churchill WH,Surgenor DM,Cho GS,McGurk S

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Despite the clinical significance of red blood cell (RBC) alloantibodies, there are currently no laboratory tests available to predict which patients may be at risk of antibody formation after transfusion exposure. Given their phagocytic and inflammatory functions, we hypothesized that differences in circula...

journal_title：Transfusion

authors： Balbuena-Merle R,Curtis SA,Devine L,Gibb DR,Karafin MS,Luckey CJ,Tormey CA,Siddon AJ,Roberts JD,Hendrickson JE

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...

journal_title：Transfusion

authors： Bassler D,Greinacher A,Okascharoen C,Klenner A,Ditomasso J,Kiefel V,Chan A,Paes B

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Patients with acute myeloid leukemia (AML) with hyperleukocytosis of at least 100 x 10(9) per L are at high risk of early death due to pulmonary or cerebral leukostasis. Although the efficacy of leukapheresis in terms of prompt cytoreduction is generally accepted, published data regarding the clinical value ...

journal_title：Transfusion

authors： Bug G,Anargyrou K,Tonn T,Bialleck H,Seifried E,Hoelzer D,Ottmann OG

更新日期：2007-10-01 00:00:00