Abstract:
:A double-blind crossover trial was conducted in 42 outpatients of either sex in order to obtain information on the properties of 7.5 mg of zopiclone in a general practice setting compared with 2 mg of flunitrazepam. Each patient went through two periods of treatment, each period lasting 10 days. A comparison of the effect of the drugs showed a significant difference with regard to effectiveness and sleep latency favoring flunitrazepam. When patient's preferences were analyzed there was a highly significant difference favoring flunitrazepam both for effectiveness and tolerance. The side effects from both drugs were generally mild.
journal_name
Pharmacologyjournal_title
Pharmacologyauthors
Wickstrøm E,Barbo SE,Dreyfus JF,Jerkø D,Kleiven R,Slåttbrekk R,Stray Tønnesen JNdoi
10.1159/000137923subject
Has Abstractpub_date
1983-01-01 00:00:00pages
165-72eissn
0031-7012issn
1423-0313journal_volume
27 Suppl 2pub_type
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