Modulation of the adrenergic system in the treatment of postoperative bowel atonia.

Abstract:

:Sympathetic hyperactivity is considered to be the most important factor in the development of postoperative bowel atonia. In a double-blind study we evaluated the gut motor effects of dihydroergotamine, which predominantly acts as a sympatholytic agent in the gastrointestinal tract. Forty-six patients undergoing cholecystectomy received either 0.5 mg dihydroergotamine + 5000 U heparin or 5000 U heparin alone (controls) twice daily in a randomized order starting on the morning of the operation. The first postoperative bowel movement occurred 57 +/- 4 h (means +/- SEM) after operation in the patients receiving dihydroergotamine, compared with 102 +/- 4 h in the control patients (p less than 0.001). Electromyography performed in the stomach and upper small bowel on the 3rd postoperative day showed an increase in the number of activity fronts of the interdigestive migrating motor complex and in the duration of spike activity under the influence of dihydroergotamine compared with the controls (p less than 0.001). It is concluded that dihydroergotamine stimulates depressed gut motility after abdominal surgery and that sympatholysis is the likely mechanism of action.

journal_name

Scand J Gastroenterol

authors

Altaparmakov I,Erckenbrecht JF,Wienbeck M

subject

Has Abstract

pub_date

1984-11-01 00:00:00

pages

1104-6

issue

8

eissn

0036-5521

issn

1502-7708

journal_volume

19

pub_type

临床试验,杂志文章,随机对照试验
  • Differences in metabolic variables between adult coeliac patients at diagnosis and patients on a gluten-free diet.

    abstract:BACKGROUND:Coeliac patients often have nutrient malabsorption with nutritional status impairment, but no report on their energy requirements is available. In this study body composition, dietary habits, basal energy expenditure, and substrate oxidation were investigated in patients with the classic form of coeliac dise...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529709028151

    authors: Capristo E,Mingrone G,Addolorato G,Greco AV,Corazza GR,Gasbarrini G

    更新日期:1997-12-01 00:00:00

  • The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease.

    abstract:BACKGROUND:Successful treatment of gastro-oesophageal reflux disease (GORD) has traditionally been assessed as healing of reflux oesophagitis, which may not be relevant in patients with moderate disease. In these patients symptom relief and patient satisfaction with therapy are of fundamental importance. Cisapride has ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.3109/00365529709002988

    authors: Hatlebakk JG,Johnsson F,Vilien M,Carling L,Wetterhus S,Thøgersen T

    更新日期:1997-11-01 00:00:00

  • The fate of intravenously injected trypsinogens in dogs.

    abstract::After intravenous injection of autologous purified and radiolabeled anionic and cationic trypsinogens in the dog, there is a multiexponential elimination from serum of the trypsinogens without activation to active trypsins. The results are in agreement with an elimination of the trypsinogens iva glomerular filtration,...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528109181969

    authors: Borgström A

    更新日期:1981-01-01 00:00:00

  • The safety and efficacy of adalimumab in patients with Crohn's disease: the experience of a single Canadian tertiary care centre.

    abstract::BACKGROUND. Adalimumab (ADA), an antitumor necrosis factor (anti-TNF) monoclonal antibody, is effective in treating moderate-to-severely active Crohn's disease (CD). ADA has been associated with a variety of adverse events (AE). The purpose of this study is to determine the safety and efficacy of ADA in CD patients in...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2013.865785

    authors: Teriaky A,Gregor J,Yan B,Ponich T,Chande N,Mosli M

    更新日期:2014-03-01 00:00:00

  • Analysis of direct medical care costs of peptic ulcer disease in a Korean tertiary medical center.

    abstract:OBJECTIVES:There have been no reported data on the medical care cost of idiopathic peptic ulcer disease (PUD) compared with H. pylori (+) and/or NSAID (+) cases although H. pylori-negative idiopathic ulcers are increasing. The aim of this study was to investigate the direct medical care costs of PUD based on whether it...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2011.639083

    authors: Kang JM,Seo PJ,Kim N,Lee BH,Kwon J,Lee DH,Jung HC

    更新日期:2012-01-01 00:00:00

  • The small-intestinal mucosa in patients with Crohn's disease assessed by scanning electron and light microscopy.

    abstract::Small-intestinal mucosal biopsy specimens obtained by a Watson capsule were assessed by light (LM) and scanning electron (SEM) microscopy in 18 patients with various sites of Crohn's disease and in 6 healthy controls. By means of LM, partial villous atrophy of the upper small-intestinal mucosa was assessed in six pati...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Nyhlin H,Stenling R

    更新日期:1984-05-01 00:00:00

  • Role of gender upon basal and postprandial systemic and splanchnic haemodynamics in humans.

    abstract:BACKGROUND:Food intake, accompanied by systemic and splanchnic haemodynamic changes, has only been studied in males. The extent to which splanchnic postprandial hyperaemia shows gender differences is unknown. METHODS:We tested 1) the splanchnic hyperaemic response to food in females and 2) whether postprandial haemody...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201750153458

    authors: Szinnai C,Mottet C,Gutzwiller JP,Drewe J,Beglinger C,Sieber CC

    更新日期:2001-05-01 00:00:00

  • Glasgow Blatchford, pre-endoscopic Rockall and AIMS65 scores show no difference in predicting rebleeding rate and mortality in variceal bleeding.

    abstract:OBJECTIVE:To compare the performance of the Glasgow Blatchford score (GBS), pre-endoscopic Rockall score (PRS) and AIMS65 score in predicting specific clinical endpoints following variceal upper gastrointestinal hemorrhage (UGIH). MATERIAL AND METHODS:Between January 2008 and December 2013, we retrospectively analyzed...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2016.1200138

    authors: Budimir I,Gradišer M,Nikolić M,Baršić N,Ljubičić N,Kralj D,Budimir I Jr

    更新日期:2016-11-01 00:00:00

  • Simultaneous measurement of gastric acid and bicarbonate secretion in man.

    abstract::Experiments were performed to validate the computerized pH/PCO2 technique for measurement of HCO3 secretion at a physiologic pH in the human stomach. In bench-side experiments the system detected 103 +/- 2% (mean +/- SE, n = 66) of boluses or infusions of NaHCO3. The standard curve was linear in the physiologic concen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528909090782

    authors: Sjövall H,Forssell H,Olbe L

    更新日期:1989-12-01 00:00:00

  • Does heparin coating reduce encrustation of biliary plastic endoprostheses? A prospective randomized trial.

    abstract:OBJECTIVE:Common bile duct stenting is widely performed for bridging benign and malignant obstructions. A major limitation is early stent occlusion making regular stent exchange necessary. Covalent binding of glycosaminoglycanes to polyethylene stents proved to reduce encrustation in urological implants. Since developm...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/00365521.2012.711849

    authors: Farnbacher MJ,Lederer R,Blana A,Schneider HT

    更新日期:2012-10-01 00:00:00

  • Interactions of cholecystokinin (CCK-PZ) and gastrin on motor activity of isolated guinea-pig antrum and fundus.

    abstract::Pressure responses to cholecystokinin (CCK-PZ, approximately 500 U/mg) and gastrin (human synthetic gastrin) were investigated in isolated guinea-pig antral and fundal pouches. Both drugs stimulated motor activity, in the antrum mainly by increasing amplitudes and rhythmic activity, in the fundus by increasing basal t...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527809182192

    authors: Gerner T,Haffner JF

    更新日期:1978-01-01 00:00:00

  • Nephrotic syndrome in ulcerative colitis.

    abstract::Complicating disorders in various organs outside the intestinal tract are common in ulcerative colitis. This report deals with the occurrence of nephrotic syndrome in two patients with long-standing ulcerative colitis. In the patient studied in most detail, 2 episodes have taken place, the first developing into uremia...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Stokke KT,Teisberg PA,Myhre E,Hovig T,Flatmark A,Gjone E

    更新日期:1976-01-01 00:00:00

  • Prevalence of gastrointestinal complaints in runners competing in a long-distance run: an internet-based observational study in 1281 subjects.

    abstract:OBJECTIVE:To assess the prevalence, risk factors and timing of gastrointestinal (GI) complaints in a large group of runners competing in a long-distance run. GI symptoms indicating GI ischaemia were of specific interest. MATERIAL AND METHODS:A questionnaire was sent by e-mail to 2076 athletes who had competed in a rec...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802321170

    authors: ter Steege RW,Van der Palen J,Kolkman JJ

    更新日期:2008-01-01 00:00:00

  • Complicated endoscopic pediatric procedures using deep sedation and general anesthesia are safe in the endoscopy suite.

    abstract:BACKGROUND:Complicated upper and lower endoscopic procedures of the gastrointestinal tract are performed in children for a variety of diagnostic and therapeutic reasons. Unlike adult patients, who receive conscious sedation, children usually require deep sedation (DS) or general anesthesia (GA). The aim of this study i...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310008467

    authors: Wengrower D,Gozal D,Gozal Y,Meiri Ch,Golan I,Granot E,Goldin E

    更新日期:2004-03-01 00:00:00

  • Secondary C-kit mutation is a cause of acquired resistance to imatinib in gastrointestinal stromal tumor.

    abstract::C-kit gene gain of function mutations are important in the pathogenesis of gastrointestinal stromal tumors (GISTs). Imatinib is a selective tyrosine kinase inhibitor of KIT and achieves a partial response or stable disease in most patients with metastatic GIST, but there is increasing evidence of acquired resistance. ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802647459

    authors: Zheng S,Pan YL,Tao DY,Wang JL,Huang KE

    更新日期:2009-01-01 00:00:00

  • Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents.

    abstract:OBJECTIVE:Clostridium difficile is a major cause of diarrhea in hospitalized patients. Although pseudomembranes are crucial evidence for diagnosis of C. difficile-associated diarrhea (CDAD), some cases do not show any pseudomembranes. The aim of this study was to verify the hypothesis that pseudomembranes are not gener...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802321238

    authors: Nomura K,Fujimoto Y,Yamashita M,Morimoto Y,Ohshiro M,Sato K,Oyake T,Kowata S,Konishi H,Yoshikawa T,Ishida Y,Taniwaki M,Japan Hematology\/Oncology Study (J-HOST) Group Kyoto.

    更新日期:2009-01-01 00:00:00

  • Carcinoma of the pancreas and papilla of Vater: presenting symptoms, signs, and diagnosis related to stage and tumour site. A prospective multicentre trial in 472 patients. Norwegian Pancreatic Cancer Trial.

    abstract::During the period 1984-87, 472 patients with histologically or cytologically verified carcinoma of the pancreas (n = 442) or the papilla of Vater (n = 30) were accrued. Diagnostic investigations were performed in accordance with the ordinary routines of 38 Norwegian hospitals. Jaundice at presentation, found in 47% of...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3109/00365529209000081

    authors: Bakkevold KE,Arnesjø B,Kambestad B

    更新日期:1992-04-01 00:00:00

  • Electrogenic transport of glucose in the normal upper duodenum. I. Technique and apparent transport constants.

    abstract::We investigated the electrogenic transport of glucose in the upper part of the duodenum in 11 healthy subjects by means of simultaneous intestinal perfusion of test solutions and measurement of the corresponding potential differences between blood and the duodenal lumen. The technique entailed continuous perfusion and...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Sparsø BH,Luke M,Wium E

    更新日期:1984-06-01 00:00:00

  • The effect of proteolytic enzymes on the vitamin B12-binding proteins of human gastric juice and saliva.

    abstract::Pepsin had no effect on the vitamin B12 binder in human saliva (R-binder), while trypsin was found to reduce the apparent molecular weight of the R-binder and to release vitamin B12 from the R-B12complex of human saliva and human gastric juice (HGJ). Trypsin had no effect on the molecular weight and biological activit...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527909181412

    authors: Andersen KJ,von der Lippe G

    更新日期:1979-01-01 00:00:00

  • Endoscopic ablation of dysplastic Barrett's oesophagus comparing argon plasma coagulation and photodynamic therapy: a randomized prospective trial assessing efficacy and cost-effectiveness.

    abstract:OBJECTIVE:Endoscopic mucosal ablation is a promising technique that is used to treat dysplastic Barrett's oesophagus. The purpose of this study was to investigate the efficacy and cost-effectiveness of two promising techniques, argon plasma coagulation (APC) and photodynamic therapy (PDT), in the ablation of dysplastic...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/00365520510015737

    authors: Ragunath K,Krasner N,Raman VS,Haqqani MT,Phillips CJ,Cheung I

    更新日期:2005-07-01 00:00:00

  • Gastrointestinal bleeding due to peptic ulcers and erosions - a prospective observational study (BLUE study).

    abstract:OBJECTIVES:Acute upper gastrointestinal bleeding is a well-recognized complication of peptic ulcers and erosions. The aim of this study was to assess the incidence rate and identify risk factors for this complication in southeastern Norway. MATERIALS AND METHODS:Between March 2015 and December 2017, a prospective obse...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1819405

    authors: Romstad KK,Detlie TE,Søberg T,Ricanek P,Jahnsen ME,Lerang F,Jahnsen J

    更新日期:2020-10-01 00:00:00

  • Endoluminal gastroplication for treatment of patients with classic gastroesophageal reflux symptoms and borderline 24-h pH studies.

    abstract:BACKGROUND:Patients with classic gastroesophageal reflux disease (GERD) symptoms and borderline 24-h pH studies are not considered to be good candidates for surgical fundoplication. Endoluminal gastroplication (ELGP) is a new endoscopic treatment for patients with GERD. The aim of this study was to evaluate the efficac...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1080/00365520410005063

    authors: Liu JJ,Carr-Locke DL,Lee LS,Brooks DC,Saltzman JR

    更新日期:2004-07-01 00:00:00

  • Dynamics and localization of activin A expression in rat gastric ulcers.

    abstract:BACKGROUND:Activin A, the homodimer of the activin/inhibin betaA subunit, has been shown to participate in cutaneous wound healing. In this study we intended to determine its part in gastric ulceration. METHODS:Activin A expression was studied by immunohistochemistry and in situ hybridization in acetic-acid-induced ch...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310000636a

    authors: Becker JC,Hertel M,Markmann A,Shahin M,Werner S,Domschke W,Pohle T

    更新日期:2003-03-01 00:00:00

  • Effects of omeprazole on gastric mucosal blood flow in the conscious rat.

    abstract::Regional blood flow in the gastrointestinal tract (forestomach, corpus, antrum, duodenum, jejunum, and colon) was determined in the conscious rat by means of the microsphere technique. The effects on blood flow were determined after omeprazole (orally and intravenously) and cimetidine (intravenously) during both basal...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991496

    authors: Mattsson H,Larsson H

    更新日期:1987-05-01 00:00:00

  • High-grade dysplastic adenoma-like mass lesions are not an indication for colectomy in patients with ulcerative colitis.

    abstract:OBJECTIVE:The management of high-grade dysplasia (HGD) in polypoid lesions in patients with ulcerative colitis (UC) is not well characterized. The purpose of this study was to characterize the clinical course of patients with HGD in adenoma-like dysplasia-associated lesion or masses (DALMs) in the absence of any synchr...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520801909686

    authors: Blonski W,Kundu R,Furth EF,Lewis J,Aberra F,Lichtenstein GR

    更新日期:2008-01-01 00:00:00

  • Evaluation of preoperative prognostic factors in patients with resectable pancreatic ductal adenocarcinoma.

    abstract::Objective: Upfront surgery is the standard treatment for resectable pancreatic ductal adenocarcinomas (R-PDACs); however, these tumors often recur. We investigated the factors governing recurrence and prognosis in patients with R-PDAC. Methods: We analyzed 359 patients who underwent upfront surgery for R-PDAC between ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1624816

    authors: Izumo W,Higuchi R,Furukawa T,Yazawa T,Uemura S,Shiihara M,Yamamoto M

    更新日期:2019-06-01 00:00:00

  • The renin-angiotensin system in Barrett's esophagus.

    abstract:OBJECTIVE:Barrett's esophagus (BE) is a risk factor for esophageal adenocarcinoma. In addition to its classical endocrine character known for hemodynamic regulation, the renin-angiotensin system (RAS) can be associated with inflammation, wound healing, and cancer. The aim of this study was to explore a potential expres...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2016.1174881

    authors: Bratlie SO,Edebo A,Casselbrant A,Helander HF,Fändriks L

    更新日期:2016-09-01 00:00:00

  • Radiofrequency ablation versus resection for the treatment of early stage hepatocellular carcinoma: a multicenter Australian study.

    abstract:OBJECTIVES:It remains unclear whether radiofrequency ablation (RFA) provides comparable outcomes to surgical resection (SR). We, therefore, compared survival outcomes of RFA to SR in patients with early stage and very early stage hepatocellular carcinoma (HCC). METHODS:A multicenter retrospective analysis was performe...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3109/00365521.2014.953572

    authors: Gory I,Fink M,Bell S,Gow P,Nicoll A,Knight V,Dev A,Rode A,Bailey M,Cheung W,Kemp W,Roberts SK,Melbourne Liver Group.

    更新日期:2015-05-01 00:00:00

  • Nomogram predicting cancer-specific survival in elderly patients with stages I-III colon cancer.

    abstract::Aim: This study aims to establish and validate an effective nomogram to predict cancer-specific survival (CSS) in elderly patients with stages I-III colon cancer.Methods: The data of elderly colon cancer patients with stages I-III were enrolled from the Surveillance, Epidemiology, and End Results database (SEER) betwe...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1720280

    authors: Zheng P,Lai C,Yang W,Guo J,Xiao S,Chen Z

    更新日期:2020-02-01 00:00:00

  • Prognostic value of clinical variables and liver histology for development of fibrosis and cirrhosis in autoimmune hepatitis.

    abstract:OBJECTIVE:In autoimmune hepatitis, data on the prognostic value of baseline liver biopsy and the sequential histology is controversial. Our aim was to evaluate the prognostic value of clinical variables and biopsy at the time of diagnosis and during the disease course. MATERIALS AND METHODS:All 98 patients in our hosp...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2016.1253768

    authors: Puustinen L,Boyd S,Mustonen H,Arkkila P,Arola J,Färkkilä M

    更新日期:2017-03-01 00:00:00