Abstract:
:Vascular prostheses with the inner diameter smaller than 1 mm were implanted to the common carotid artery of rats, and their patency was examined. Four types of tubes were prepared for this purpose in Experiment 1: polyethylene (PE), poly-(acrylic acid)-grafted polyethylene (PE-AA), polyacrylamide-grafted polyethylene (PE-AAm), and poly(vinyl alcohol) (PVA) tubes. Comparative studies made using nonsuture anastomosis revealed that the PE-AAm and PVA tubes were antithrombotic, although disconnection was noted at the anastomotic sites within 1 week and 1 month, respectively. Thereafter in Experiment 2, the PVA tubes were implanted to the common carotid artery of 20 rats using conventional anastomosis. Neither anticoagulants nor fibrinolytic agents were used in both series of experiments. Patency of the PVA tubes was 80% after 1 week and 70% after 1 month. In patent cases after 1 month, the luminal surfaces of the prostheses and the host arteries were examined using scanning electron microscopy. The lumen of the arteries and anastomotic sites was covered with endothelial cells, while the lumen of the PVA tubes was free from thrombi and there was no neointima formation. So far, there has been reported no manmade material that has completely antithrombotic property in vivo. However, our studies disclosed that PVA is antithrombotic and one of the most promising materials for the inner surface of small vascular prostheses.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Miyake H,Handa H,Yonekawa Y,Taki W,Naruo Y,Yamagata S,Ikada Y,Iwata H,Suzuki Mdoi
10.1002/micr.1920050310subject
Has Abstractpub_date
1984-01-01 00:00:00pages
144-50issue
3eissn
0738-1085issn
1098-2752journal_volume
5pub_type
杂志文章相关文献
MICROSURGERY文献大全abstract::We present herein a case of massive arterial thrombosis of a free rectus abdominal musculocutaneous flap used for reconstructive surgery of gingival carcinoma that could not be rescued. A 54-year-old woman underwent the operation. She had experienced two miscarriages in her 20s, but medical history was otherwise uneve...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20734
更新日期:2010-01-01 00:00:00
abstract::Single flap for complex hypopharyngoesophageal and anterior neck skin defect reconstruction is still a challenge for reconstructive surgeons. Herein, we present five patients, with advanced hypopharyngeal cancer and anterior neck skin invasion, which received a single anterolateral thigh (ALT) fasciocutaneous flap for...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20906
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Free tissue transfer is commonly used in the reconstruction of post-ablative defects of the mandible. Due to lack of statistical power, comparing the survival of various free flaps, even in large studies, is challenging. The purpose of this study was to perform a meta-analysis comparing the survival of the m...
journal_title:Microsurgery
pub_type: 杂志文章,meta分析,评审
doi:10.1002/micr.22471
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Groin dissection is the procedure with the highest risk of lower limb lymphedema.As lymph stasis causes irreversible alterations to the limb over time,therapies should be administered in early stages,or better yet, lymphatic drainage impairment should be prevented.We developed a new preventive approach to lym...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30142
更新日期:2017-09-01 00:00:00
abstract::It is generally known that low-intensity pulsed ultrasound (LIPUS) accelerates peripheral nerve tissue regeneration. However, the precise cellular mechanism involved is still unclear. The purpose of this study was to determine how the Schwann cells respond directly to LIPUS stimuli. Thus, we investigated the effect of...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20644
更新日期:2009-01-01 00:00:00
abstract::Bile reflux may play a key role for esophageal carcinogenesis in reflux disease. In search for bile-specific effects, the animal model of esophageal cancer was applied in a mutagenesis assay. Big Blue transgenic mice were operated with microsurgical techniques. Seven had total gastrectomy with esophagojejunostomy crea...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20424
更新日期:2007-01-01 00:00:00
abstract::The aim of the experimental model to develop a spleen transplant model in mice to study the role of spleen in autoimmune and transplant rejection. After a midline incision, splenectomy was performed. Four tiny segments were cut from the removed spleen and were rinsed at room temperature in physiological salt solution....
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1026
更新日期:2001-01-01 00:00:00
abstract::Recent supermicrosurgical techniques have developed the possibility for vascular anastomosis of smaller vessels and it is now safe and sound to perform precise anastomoses between lymphatics and venules. Reported here is the 2 years experience on supermicrosurgical lymphaticovenular anastomosis and/or lymphaticovenous...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20665
更新日期:2009-01-01 00:00:00
abstract::Heart and spleen twin grafts from LEW to ACI rats may survive permanently, whereas those grafted from ACI to LEW rats do not. This strain difference in graft acceptance was analyzed quantitatively by transplanting one to three ACI spleens into LEW rats in order to compensate for the relatively small size of ACI spleen...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920040407
更新日期:1983-01-01 00:00:00
abstract::This study aims to compare donor-site morbidity between the traditional fibula osteocutaneous and chimeric fibula flaps for mandibular reconstruction. Twenty-three patients with head and neck cancer were recruited. Fifteen patients underwent the traditional fibula osteocutaneous flap. Eight patients received a chimeri...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20955
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Vascularised composite allo-transplantation (VCA) is emerging as a tailored approach for complex tissue reconstruction. This study focuses on the quadriceps VCA as a potential solution for tissue repair, following trauma, necrotising fasciitis/myositis, or tumor ablation. METHODS:Dissections were undertaken...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30479
更新日期:2020-02-01 00:00:00
abstract::It is clear that the late clinical symptomatology and the patency of forearm arterial repairs have been contradictory. This study, during which the relationship between the symptomatology and patency has been studied, explores the influence of the local hemodynamic changes and the effect of microsurgical technique on ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1006
更新日期:2001-01-01 00:00:00
abstract::Neurorraphy, conventional nerve grafting technique, and artificial nerve conduits are not enough for repair in severe injuries of peripheral nerves, especially when there is separation of motor nerve from muscle tissue. In these nerve injuries, reinnervation is indicated for neurotization. The distal end of a peripher...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10044
更新日期:2002-01-01 00:00:00
abstract::The results of a 3-year study in which a series of 355 implantations of 1-cm-long fibrous polyurethane microvascular prostheses into the infrarenal aorta of the rat (group A) were evaluated with respect to patency and formation, structure, and fate of the neo-intima. Rats were sacrificed at various intervals from 1 da...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920060306
更新日期:1985-01-01 00:00:00
abstract::A 23-year-old male patient was operated for a soft tissue defect of the spine using a free musculocutaneous latissimus dorsi flap with two 21-cm long venous grafts connecting the flap to its vascular supply at the thoracodorsal vessels. This young patient suffered from Noonan's Syndrome that is a complex hereditary ma...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20625
更新日期:2009-01-01 00:00:00
abstract::The standard superficial epigastric artery flap has become a reliable model for flap research. The purpose of this study was to design a flap model in the rat, with the possibility of intraoral coverage of defects. A fat flap based only on the medial trunk of the superficial epigastric vessels was generated, raised to...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20539
更新日期:2008-01-01 00:00:00
abstract::Two hundred twenty patients with soft tissue defects in the hand and forearm were treated with 226 free and island flap transfers. Reconstructed sites involved the thumb in 74 cases, the fingers in 117, the hand in 30, and the forearm in 5. Seventy-nine patients received 82 free flaps, and 141 patients received 144 is...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2752(1996)17:3<150::AID-MICR10>
更新日期:1996-01-01 00:00:00
abstract::This paper reviews the history of attempts to study peripheral nerve regeneration, focusing upon pharmacologic agents that may prove to be useful clinically. In particular, forskolin is described as a model for such an agent, and its mechanism of action, as a stimulator of the cyclic AMP second messenger system, is de...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.1920100211
更新日期:1989-01-01 00:00:00
abstract::Composite tissue allografts (CTAs) contain their own reservoir of vascularized bone marrow, offering novel aspects for the induction of donor-specific tolerance. Additionally, the manipulation of recipient dendritic cells, pulsed with donor allopeptide, has been shown to engender solid organ allograft survival. To exp...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20314
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Purpose of the article is to present the use of the scapular tip free flap (STFF) for the reconstruction of oromandibular defects. PATIENTS:Eleven patients who underwent oromandibular reconstruction with STFF were retrospectively evaluated with regards to form and function assessing mouth opening, dietary inta...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22285
更新日期:2015-02-01 00:00:00
abstract::There is evidence that nerve flaps are superior to nerve grafts for bridging long nerve defects. Moreover, arterialized neurovenous flaps (ANVFs) have multiple potential advantages over traditional nerve flaps in this context. This paper describes a case of reconstruction of a long defect of the ulnar artery and nerve...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.30265
更新日期:2018-02-01 00:00:00
abstract::The effects of tension at the site of coaptation on recovery of sciatic nerve function after neurorrhaphy were studied by evaluating walking-track measurements, nerve conduction velocity measurements, histomorphometry, and electron probe X-ray microanalysis. Forty adult male Lewis rats underwent right sciatic nerve (S...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1999)19:4<200::aid-micr7>3
更新日期:1999-01-01 00:00:00
abstract::Improved microsurgical techniques for kidney transplantation in the mouse are described. Left renal transplantation is performed with end-to-side anastomoses of the donor renal vein to the inferior vena cava and the donor aortic cuff to the aorta. Urinary tract reconstruction is accomplished by suturing the donor uret...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920160212
更新日期:1995-01-01 00:00:00
abstract::Despite increasing use of lateral lower leg perforator flaps, comprehensive anatomical data are still lacking. The aim of this article was to comprehensively document the pattern of usable lateral lower leg perforators. Systematic mapping of 16 cadaver leg perforators in a well-defined area was performed to elucidate ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22313
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Extensive full thickness abdominopelvic defects pose a difficult challenge to surgeons. Autologous tissues are versatile and can provide a satisfying reconstructive option for this type of defects. The tensor fascia latae (TFL) and superficial circumflex iliac perforator (SCIP) flaps provide a large area of ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30391
更新日期:2020-01-01 00:00:00
abstract::This study examines the effects of combination therapy with the nitric oxide (NO) donor S-nitroso-N-acetylcysteine (SNAC) and the iNOS inhibitor N-(3-(aminomethyl)benzyl) acetamidine (1400W) on contractile function in reperfused rat skeletal muscle. The right extensor digitorum longus (EDL) muscles of 104 rats were su...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20122
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:In the lower leg posttraumatic pathology, we are frequently confronted with tissue defects that are difficult to cover by local or distance means, because of either the poor tissue quality or the precarious local vessels. One of the still available methods for solving these cases remains the cross-leg flap. ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20375
更新日期:2007-01-01 00:00:00
abstract::Reconstruction of complex back defects is challenging for reconstructive surgeons, as it should preserve function, provide adequate coverage, and minimize morbidity. We present a case of multiple-step reconstruction after resection of a large squamous cell carcinoma recurrence in a 68-year-old man, with local perforat...
journal_title:Microsurgery
pub_type:
doi:10.1002/micr.30615
更新日期:2020-07-01 00:00:00
abstract::The secondary lymphedema of the upper limb (post-mastectomy lymphedema) has an incidence, in patients who underwent axillary lymphadenectomy for breast cancer, between 5 to 25%, up to 40% after radiotherapic treatment. We studied 50 patients treated for breast cancer. The patients were divided in two groups of 25 each...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20215
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Venous congestion is the most common vascular complication of the deep inferior epigastric artery perforator (DIEP) flaps. Adding a second venous drainage by anastomosing a flap vein and a recipient vein (super-drainage) is considered the solution of choice. Evidence to support this procedure, had not yet ...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.30682
更新日期:2020-11-10 00:00:00