Abstract:
BACKGROUND:Vascularised composite allo-transplantation (VCA) is emerging as a tailored approach for complex tissue reconstruction. This study focuses on the quadriceps VCA as a potential solution for tissue repair, following trauma, necrotising fasciitis/myositis, or tumor ablation. METHODS:Dissections were undertaken in 10 adult cadaveric lower limbs to characterize the blood supply to the quadriceps femoris for en bloc muscle allo-transplantation. A mock cadaveric transplantation was performed to (a) define the best neurovascular VCA design and (b) test the feasibility of the procedure. A review of 54 archival radiograph studies from the institution was also performed to further evaluate the muscle vasculature. RESULTS:In two lower limbs, the quadriceps VCA was harvested designed on the common and superficial femoral vessels and nerve, which revealed a lengthy and bloody dissection, especially of the veins, which could increase clinically with the inability to use a tourniquet for most of the dissection. However, review of our previous archival studies showed that all four quadriceps muscles are supplied within the lateral circumflex femoral angiosome. In a further eight lower limbs, the quadriceps femoris muscle group consistently received its blood supply from the lateral circumflex femoral angiosome, verified by selective lead oxide injections of this artery. The vastus medialis appeared to have a more tenous blood supply distally based on this angiosome. A successful mock cadaveric transplant was performed based on this data. CONCLUSIONS:We suggest that the best neuromuscular quadriceps VCA should be (a) designed on the lateral circumflex femoral pedicle, (b) should be raised from distal to proximal, and (c) should include the descending genicular vessels as a potential supplemental supply to vastus medialis, should all four muscles be required.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Sparks DS,Taylor GI,Gascoigne A,Corlett RJ,Ashton MWdoi
10.1002/micr.30479subject
Has Abstractpub_date
2020-02-01 00:00:00pages
189-199issue
2eissn
0738-1085issn
1098-2752journal_volume
40pub_type
杂志文章相关文献
MICROSURGERY文献大全abstract::The single-anastomosis heart-lung transplantation method in the rat developed by Lee and associates has been examined and has proven to be simple and reproducible. Technical procedures are discussed emphasizing those procedures that require special caution to ensure successful graft function. The donor and recipient r...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920080411
更新日期:1987-01-01 00:00:00
abstract::We examined the results after implantation of ovarian follicles by various modes in a total of 82 cases. One or five ovarian follicles were implanted into spleens in castrated female rats. In 20 cases among these, each five follicles were implanted into native and transplanted spleens after spleen transplantation (dou...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10186
更新日期:2003-01-01 00:00:00
abstract::It is clear that the late clinical symptomatology and the patency of forearm arterial repairs have been contradictory. This study, during which the relationship between the symptomatology and patency has been studied, explores the influence of the local hemodynamic changes and the effect of microsurgical technique on ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1006
更新日期:2001-01-01 00:00:00
abstract::Significant evolution has been made concerning resuscitation and emergency management of severely burned patients, and nowadays most patients will survive and deal with burns sequelae. They constitute a reconstructive challenge, mainly because options and donor areas are frequently compromised, results are often limit...
journal_title:Microsurgery
pub_type:
doi:10.1002/micr.30646
更新日期:2020-10-01 00:00:00
abstract::Transplants of the cranial portion of the dog sartorius muscle were able to generate 70% of control force after 3 months if the artery, vein, and nerve were reanastomosed. Our histological and histochemical findings correlate with the functional findings. In a separate group of animals that had their muscles denervate...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920070302
更新日期:1986-01-01 00:00:00
abstract::The iliac crest is reevaluated with respect to the rapid evolution of vascularized mandibular reconstruction. With more flaps to choose from, indications for the crest have become more specific-playing to the strengths of this particular transfer. Ideally, defects should exclude soft tissue and occupy lateral segments...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920150406
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:In this study, the surgical outcomes of 32 patients with ulnar nerve injuries in the Guyon canal are presented. Outcomes were analyzed in relation to various factors such as age, surgical timing, zone of injury, and type of nerve reconstruction. METHODS:Between 1990 and 2007, 32 patients with injury in Guyon c...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.21951
更新日期:2012-05-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of wrapping bioabsorbable nerve conduit around primary suture repair on motor nerve regeneration in a rat model. Forty rats were randomly divided into two experimental groups according to the type of repair of the rat sciatic nerve: group I had primary suture repair...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22274
更新日期:2014-10-01 00:00:00
abstract::We have previously shown that the epigastric flap in Dark Agouty rats, measuring approximately 6 x 4 cm with borders related to well-defined anatomical structures, does not exhibit an all-or-none survival pattern. This study was designed to investigate the survival pattern of non-revascularized epigastric flaps in thr...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920140907
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The medial thigh is a well-hidden area. The two most common flaps from this area are the transverse upper gracilis (TUG) and profunda artery perforator (PAP) flaps. Herein, we explored the applications of combined TUGPAP flap to reconstruct large and complex defects in different regions. METHODS:Between Nov...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30413
更新日期:2019-05-01 00:00:00
abstract::In order to raise an abundant and accessible reservoir for Schwann cells (SCs), which are used as seed cells for constructing tissue-engineered nerve grafts, we investigated the feasibilty of in vivo differentiation of bone marrow stromal cells (MSCs) into SC-like cells. In this study, MSCs were harvested from adult r...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20184
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:We describe a new dual neurorrhaphy method for a free abdominal-based flap and compare sensory recovery with this novel technique to that with conventional neurorrhaphy technique for breast reconstruction. METHODS:70 breast cancer patients underwent muscle sparing innervated transversal rectus abdominis myo...
journal_title:Microsurgery
pub_type: 临床试验,杂志文章
doi:10.1002/micr.30064
更新日期:2017-01-01 00:00:00
abstract::There is a lack of agreement regarding the potential for peripheral nerve cells with short axons to regenerate and innervate the terminal end organs of nerve cells with long axons. We designed a study to evaluate experimentally the possibility of neurons to reconstitute much longer axonal segments. Twenty Wistar rats ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920110203
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:The probability of spontaneous recovery of shoulder external rotation in neonatal brachial plexus injury (NBPI) is very low after the age of 18 months. We report the outcomes of double nerve transfers to restore active external rotation of the glenohumeral joint in children with NBPI after this age. PATIE...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30616
更新日期:2020-11-01 00:00:00
abstract::In this retrospective study, the survival rates of fingertip replantation with and without vein grafting were evaluated along with their postoperative functional and cosmetic results. One hundred twenty-one-fingertip amputations were performed in 103 patients between September 2002 and July 2007. Thirty-four amputated...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20614
更新日期:2009-01-01 00:00:00
abstract::A 4-year-old girl who sustained the hemiplegic cerebral palsy and subsequent spasticity in the left upper extremity underwent the C7 nerve root rhizotomy and the contralateral C7 nerve root transfer to the ipsilateral middle trunk of brachial plexus through an interpositional sural nerve graft. In a 2-year follow-up, ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20877
更新日期:2011-07-01 00:00:00
abstract::Both hypotension and hypertension aggravate the damage of reperfusion injury after reconstructive microsurgery. The purpose of this study is to establish a theoretical guide for postoperative blood pressure control in optimizing the cutaneous perfusion and flap survival. Systemic arterial pressure was altered by the i...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20627
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Reconstructing soft tissue defect on the trochanteric area is challenging. Due to the significant complications associated with regional flap, free tissue transfer is an appropriate option. However, this area has poor recipient vessels. Therefore, we present perforators as suitable recipient vessels to facil...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30424
更新日期:2020-01-01 00:00:00
abstract::An experimental model of a free, empty perineurial tube for use as a nerve graft is presented as an alternative to existing methods. The technique is described and the model compared with conventional nerve graft in the sciatic nerve of a rabbit. Results are evaluated with EMG studies, angiography, and histology. The ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920040207
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:Groin dissection is the procedure with the highest risk of lower limb lymphedema.As lymph stasis causes irreversible alterations to the limb over time,therapies should be administered in early stages,or better yet, lymphatic drainage impairment should be prevented.We developed a new preventive approach to lym...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30142
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:Mandibular reconstruction with a mandibular reconstruction plate (MRP) and free flap transfer can involve serious plate-related complications. The aim of our study is to present our new "no-touch-technique" which keeps an MRP not contaminated to saliva during the entire operation for the reduction of plate-re...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22403
更新日期:2016-02-01 00:00:00
abstract::A crush-avulsion anastomosis model was established on the rat femoral vein. Saline or heparin was used as a luminal topical agent and was allowed to contact the damaged endothelium for 10 min. Patency and coagulation parameters were investigated for 1 week. The heparin treated group had a patency rate of 93% at 1 hr v...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920160806
更新日期:1995-01-01 00:00:00
abstract::This study evaluated the results of repair of the radius defect with a vascularized tissue engineered bone graft composed by implanting mesenchymal stem cells (MSCs) and a vascular bundle into the xenogeneic deproteinized cancellous bone (XDCB) scaffold in a rabbit model. Sixty-four rabbits were used in the study. Amo...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20854
更新日期:2011-02-01 00:00:00
abstract:INTRODUCTION:Venous congestion is the most common vascular complication of the deep inferior epigastric artery perforator (DIEP) flaps. Adding a second venous drainage by anastomosing a flap vein and a recipient vein (super-drainage) is considered the solution of choice. Evidence to support this procedure, had not yet ...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.30682
更新日期:2020-11-10 00:00:00
abstract::We present our experience with reconstruction after resection of tumors around the knee, using free vascularized fibular grafting. The study included 23 patients. The lower femur was involved in 17 cases, the upper tibia in 6. The cases included giant cell tumor of the lower femur (2 patients), giant cell tumor of the...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/1098-2752(2000)20:5<233::aid-micr4>3.0.co;
更新日期:2000-01-01 00:00:00
abstract::In this report, we present a case of treatment of fibrous dysplasia (FD) of the proximal femur with the pedicled iliac crest bone graft. An 18-year-old patient presented with hip pain and polyostotic dysplasia with involvement of the proximal femur and a history of pathological fracture. The patient was operated on us...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20830
更新日期:2011-01-01 00:00:00
abstract::The aim of this study was to investigate the rate of disappearance of noradrenaline in arterial grafts after their transplanation. Arterial grafts were harvested from AO/Ks:OC strain rats. In each rat, a graft was harvested from the femoral artery and transplanted into the common carotid artery. A contralateral unoper...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20004
更新日期:2004-01-01 00:00:00
abstract::Femoral nerve lesions are uncommon, but very distressing at the functional level because of the absence of knee locking mechanism by the quadriceps muscle. We propose here a new neurotization procedure of obturator nerve motor branches to the motor portion of the femoral nerve in the thigh. This study was conducted on...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22012
更新日期:2012-09-01 00:00:00
abstract::Although the devices for large-caliber vessel (>2-mm diameter) anastomosis are available, there are no devices for performing anastomosis of small-caliber vessels. We designed a hooked device composed of a bioabsorbable polymer for sutureless anastomosis of small-caliber vessels. The efficacy of this device was evalua...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20764
更新日期:2010-09-01 00:00:00
abstract::We report a case of combined two toe transfer after distal ulnar artery fasciocutaneous flap in a 10-year-old boy who has four-digit amputation. Four years after the operation, satisfactory results were obtained both functionally and cosmetically. ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10101
更新日期:2003-01-01 00:00:00