Sevelamer is cost effective versus calcium carbonate for the first-line treatment of hyperphosphatemia in new patients to hemodialysis: a patient-level economic evaluation of the INDEPENDENT-HD study.

abstract：BACKGROUND:Congenital nephrotic syndrome is an uncommon disorder that may be caused by several diseases. These may be inherited, sporadic, acquired or part of a general malformation syndrome. METHODS:We reviewed the clinical characteristics, pathologic findings, and results of medical management in 30 infants who pres...

journal_title：Journal of nephrology

authors： Hamed RM,Shomaf M

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Malnutrition is common and associated with poor outcomes in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Recently, the geriatric nutritional risk index (GNRI) was reported as a novel tool for evaluating nutritional status. However, the association between GNRI and renal outc...

journal_title：Journal of nephrology

authors： Xiong J,Wang M,Wang J,Yang K,Shi Y,Zhang J,Zhang B,Zhang L,Zhao J,Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE).

更新日期：2020-08-01 00:00:00

abstract：:Thales was born into a noble family of Phoenician origin at the time of the 25th Olympiad (floruit 585 bc; he was 40 in the year of the solar eclipse. He had no teachers but had occasion to learn from Egyptian priests. He developed into a scholar and politician very much appreciated by Heraclitus, Herodotus and Democr...

journal_title：Journal of nephrology

authors： De Santo NG,Bisaccia C,Bilancio G,Romano M,Cirillo M

更新日期：2009-11-01 00:00:00

abstract：:There is little doubt that molecular biological intervention therapy has come of age and its potential is arousing tremendous excitement. A gene transfer technique, the HVJ-liposome method, is now applicable as a tool for the dissection of molecular aspects in the pathophysiology of renal diseases, and for gene therap...

journal_title：Journal of nephrology

authors： Imai E,Isaka Y,Akagi Y,Kaneda Y,Hori M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Recently, some studies have emphasized the role of plasma 25-(OH)vitamin D (25OHD) levels in mineral metabolism dysregulation in chronic kidney diseases (CKDs). However, to date little attention has been paid to 25OHD metabolism abnormalities after renal transplantation (Tx). This cross-sectional study aimed...

journal_title：Journal of nephrology

authors： Lomonte C,Antonelli M,Vernaglione L,Cazzato F,Casucci F,Chimienti D,Bruno A,Cocola S,Verrelli EA,Basile C

更新日期：2005-01-01 00:00:00

abstract：:The hallmark of IgA nephropathy (IgAN) is macroscopic hematuria coinciding with, or immediately following, a mucosal infection, usually of the upper respiratory airways. The role of mucosal pathogens has been proven in different experimental models. Mucosal (or innate) immunity acts through the recognition of pathogen...

journal_title：Journal of nephrology

authors： Coppo R,Amore A,Peruzzi L,Vergano L,Camilla R

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Serum adiponectin is inversely linked to obesity, impaired glucose homeostasis, dyslipidemia and hypertension and has been suggested as a possible marker of cardiovascular (CV) disease in the general population. However, its role in chronic kidney disease and following renal transplantation is not well estab...

journal_title：Journal of nephrology

authors： Chitalia N,Raja RB,Bhandara T,Agrawal P,Kaski JC,Jha V,Banerjee D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Arterial stiffness is a risk factor for chronic kidney disease progression (CKD). Pulse pressure is a surrogate marker of arterial stiffness. It is unclear if pulse pressure predicts CKD progression in type 2 diabetes mellitus. METHODS:This was prospective study involving 1494 patients with estimat...

journal_title：Journal of nephrology

authors： Low S,Moh A,Ang SF,Lim CL,Liu YL,Wang J,Ang K,Tang WE,Kwan PY,Lim Z,Subramaniam T,Sum CF,Lim SC

更新日期：2021-01-25 00:00:00

abstract：:Diabetic kidney disease (DKD) affects approximately one-third of patients with diabetes and taking into consideration the high cardiovascular risk burden associated to this condition a multifactorial therapeutic approach is traditionally recommended, in which glucose and blood pressure control play a central role. The...

journal_title：Journal of nephrology

authors： Leoncini G,Viazzi F,De Cosmo S,Russo G,Fioretto P,Pontremoli R

更新日期：2020-10-01 00:00:00

abstract：:Organ transplantation has proven to be an effective therapeutic for a wide variety of disease states, but the chronic immunosuppression required for allograft survival increases the risk for infection and neoplasia. In the past 50 years, a wealth of experimental data has been accumulated relating to strategies to pres...

journal_title：Journal of nephrology

authors： Casiraghi F,Aiello S,Remuzzi G

更新日期：2010-05-01 00:00:00

abstract：:Aortic intimal sarcoma is a rare tumor with poor prognosis. The most common manifestations are thromboembolic phenomena and vascular obstruction. We present a case of aortic intimal sarcoma causing bilateral renal artery stenosis which manifested as resistant hypertension and acute kidney inury. Multiple attempts to s...

journal_title：Journal of nephrology

authors： Sethi S,Pothineni NK,Syal G,Ali SM,Krause MW

更新日期：2013-09-01 00:00:00

abstract：:IgA nephropathy (IgAN) is characterised by the mesangial deposition of polymeric IgA1 (pIgA1). pIgA1 production is reduced in the mucosal immune system in IgAN and increased in the marrow; this switch may be secondary to a defect in gammadeltaT cell control of IgA production. However this does not explain the mechanis...

journal_title：Journal of nephrology

authors： Feehally J,Allen AC

更新日期：1999-03-01 00:00:00

abstract：:The kidney does not usually present specific lesions in cystic fibrosis (CF), although in recent years renal involvement has been reported, particularly amyloidosis and immune complex glomerulonephritis. IgA nephropathy is rare. We report four cases of IgA nephropathy out of five renal biopsies performed in the last t...

journal_title：Journal of nephrology

authors： Stirati G,Antonelli M,Fofi C,Fierimonte S,Pecci G

更新日期：1999-01-01 00:00:00

abstract：:Clinical immunology laboratories play an essential role in diagnosis and monitoring of systemic lupus erythematosus (SLE). To obtain the best results in terms of diagnostic performance and clinical usefulness, the following recommendations should be fulfilled: Indirect immunofluorescence on Hep-2 cells remains the met...

journal_title：Journal of nephrology

authors： Sinico RA,Bollini B,Sabadini E,Di Toma L,Radice A

更新日期：2002-11-01 00:00:00

abstract：:The role of the kidney in controlling and maintaining plasma potassium levels in the normal range requires the presence and activity of renal potassium channels, and their importance has been highlighted in patients with Bartter syndrome harboring mutations in the ROMK (Kir1.1, KCJN1) channel and hyperkalemia. However...

journal_title：Journal of nephrology

authors： Wagner CA

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Accurate assessment of kidney function level is the key to the identification and management of chronic kidney disease (CKD). Glomerular filtration rate (GFR) is the best measure of overall kidney function in health and disease. There is no consensus about the method to be used routinely to measure and/or es...

journal_title：Journal of nephrology

authors： Nóbrega AM,Gomes CP,Lemos CC,Bregman R

更新日期：2006-03-01 00:00:00

abstract：:Chronic renal failure (CRF) is associated with a 20-fold increased risk of cardiovascular death, two principal mechanisms being: sudden, arrhythmic death associated with left ventricular hypertrophy, and ischaemic heart disease, associated with accelerated atherosclerosis. In recent years, the vascular endothelium has...

journal_title：Journal of nephrology

authors： Morris ST,Jardine AG

更新日期：2000-03-01 00:00:00

abstract：:On September 11, 1945, Maria Schafstaat was the first patient who successfully underwent a dialysis treatment for acute kidney injury (AKI). The ingenious design of the first dialysis machine, made of cellophane tubing wrapped around a cylinder that rotated in a bath of fluid, together with the brave determination to ...

journal_title：Journal of nephrology

authors： Kielstein JT,Schiffer M,Hafer C

更新日期：2010-09-01 00:00:00

abstract：:Primary renal non-Hodgkin's lymphoma is very rare in childhood. A six-year-old boy presented with bilateral non-obstructive multinodular nephromegaly and renal failure. Percutaneous needle biopsy showed large-cell lymphoma. The patient was started on chemotherapy. A right nephrectomy was done when systemic hypertensio...

journal_title：Journal of nephrology

authors： Karadeniz C,Oguz A,Ataoglu O,Citak C,Buyan N,Pinarli G,Ozkaya O,Kapucu O

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Adiponectin, a novel adipocytokine with antiinflammatory and antiatherosclerosis properties, has been found to be an inverse predictor of cardiovascular outcomes among uremic patients on hemodialysis. However, its role in uremic patients on continuous ambulatory peritoneal dialysis (CAPD) remains unclear. Th...

journal_title：Journal of nephrology

authors： Tsao YT,Hsu YJ,Chu NF,Lai CH,Chiu JS,Lin SH

更新日期：2008-09-01 00:00:00

abstract：:Autosomal recessive and autosomal dominant polycystic kidney disease (ADPKD and ARPKD) are 2 major variants of inherited diseases leading to the cystic degeneration of the kidney and other organs. Primary cilia have moved into the focus of research as it is becoming increasingly clear that dysfunction of this special ...

journal_title：Journal of nephrology

authors： Wagner CA

更新日期：2008-01-01 00:00:00

abstract：:The analysis of the urinary proteome is a potential source of information regarding the kidney's physiopathology. A clear knowledge of the protein composition of normal urine is an essential prerequisite to looking at its pathology. Technological evolution in the field of proteomics (2-dimensional [2D] electrophoresis...

journal_title：Journal of nephrology

authors： Santucci L,Candiano G,Bruschi M,Bodria M,Murtas C,Petretto A,Ghiggeri GM

更新日期：2013-07-01 00:00:00

abstract：:Recently, two independent teams detected presumed hepatitis agents, which were designated HGV and hepatitis GB virus C; they represent a new genus in the family Flaviviridae. The most accurate way to assess the epidemiology of GBV-C/HGV infection remains the combination of RT-PCR and anti-GBV-C/HGV E2 techniques, to d...

journal_title：Journal of nephrology

authors： Fabrizi F,Martin P

更新日期：1999-05-01 00:00:00

abstract：:Hyperlipidaemia complicating the nephrotic syndrome is characterised by elevated levels of total and LDL cholesterol, often with hypertriglyceridaemia and low HDL cholesterol levels. The underlying mechanisms are complex but involve abnormalities of both lipoprotein synthesis and catabolism. Experience to date suggest...

journal_title：Journal of nephrology

authors： Wheeler DC

更新日期：2001-11-01 00:00:00

abstract：:To determine the clinical impact of conversion from C0 to C2 Neoral monitoring, we conducted a 6-month prospective study in 62 stable renal transplant recipients. Neoral was given alone (19%), with steroids (31%), combined with azathioprine (Aza) or mycophenolate mofetil (MMF) (50%). C0 and C2 target ranges were, resp...

journal_title：Journal of nephrology

authors： Sandrini S,Bossini N,Setti G,Mazzucchelli C,Maiorca P,Cancarini G

更新日期：2004-03-01 00:00:00

abstract：:Evidence-based medicine provides tools to evaluate dialysis outcomes by integrating knowledge obtained from interventional and observational studies. This is illustrated in relation to three important topics: dialysis membranes, dialysis dose and anemia. Clinical trials and observational evidence support each other in...

journal_title：Journal of nephrology

authors： Locatelli F,Andrulli S,D'Amico M

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The response of proximal convoluted tubules (PCTs) to angiotensin II is mediated by specific type 1 receptors found on both apical and basolateral surface membrane cells. After ligand association with type 1 receptors, different signaling pathways are triggered and determine changes in fluid absorption (Jv)....

journal_title：Journal of nephrology

authors： Bertels IM,Gontijo JA,Figueiredo JF

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Gut-derived uremic toxins have been associated with adverse outcomes in chronic kidney disease (CKD). Alterations in bowel habits, including constipation, seem to play an additional role in uremic toxicity. The aim of this study is to investigate the association of bowel habits with gut-derived uremic toxins...

journal_title：Journal of nephrology

authors： Pereira NBF,Ramos CI,de Andrade LS,Teixeira RR,Nakao LS,Rodrigues SD,de Lima JD,Dalboni MA,Cuppari L

更新日期：2020-10-01 00:00:00

abstract：:Patients with chronic kidney disease (CKD) have a greatly enhanced risk of cardiovascular morbidity and mortality. Over the past decade it has come clear that a disturbed calcium-phosphate metabolism, with Fibroblast Growth Factor-23 as a key hormone, is partly accountable for this enhanced risk. Numerous studies have...

journal_title：Journal of nephrology

authors： Bouma-de Krijger A,Vervloet MG

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Improved responsiveness to erythropoiesis stimulating agents (ESAs) in patients on on-line post-dilution hemodiafiltration (Post-HDF) compared with conventional hemodialysis (HD) was reported by some authors but challenged by others. This prospective, cross-over randomized study tested the hypothesis that an...

journal_title：Journal of nephrology

authors： Pedrini LA,Comelli M,Ruggiero P,Feliciani A,Manfrini V,Cozzi G,Castellano A,Pezzotta M,Gatti G,Arazzi M,Auriemma L,di Benedetto A,Stuard S

更新日期：2020-10-01 00:00:00