Abstract：
:Adaptively responding to acute stress has been of great importance for human and animal survival. However, for our species, stress-related disorders are putting an ever-increasing burden on healthcare systems. It is thus crucial to understand the basic processes and cognitive changes associated with acute stress. Here, we examined the effects of acute stress exposure on spatial (water maze) and memory (delayed match to sample and episodic-memory-like tasks) performance. We found striking performance deficits in stressed animals navigating in the water maze. We also found, in an episodic-like memory task, striking object-location deficits, but not in temporal-object association learning in stressed animals. Finally, no differences were apparent for any delay periods (up to 30s) in a delayed match to sample task. Taken together, these results show a strong differential effect of acute stress on differing memory processes.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Passecker J,Barlow S,O'Mara SMdoi
10.1016/j.bbr.2014.07.007subject
Has Abstractpub_date
2014-10-01 00:00:00pages
218-25eissn
0166-4328issn
1872-7549pii
S0166-4328(14)00447-1journal_volume
272pub_type
杂志文章abstract：:Unilateral lesions of the superior colliculus produce contralateral neglect. This study determined if bilateral lesions would impair head orientation in a way expected from the summation of two contralateral neglects. Rats were trained to make various head movements to get water at a 3 x 3 array of holes, each with a ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90039-3
更新日期：1988-02-01 00:00:00
abstract：:The behavioural responses to two commonly used 'predator odours' were assessed in male Wistar rats. Cat odour was presented to rats in the form of a piece of collar that had been worn by a domestic cat. Fox odour was presented in an equivalent piece of (unworn) collar that had been impregnated with 2,4,5 Trimethylthia...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(01)00324-2
更新日期：2002-02-01 00:00:00
abstract：:The effects of N-methyl-D-aspartate NMDA receptor antagonists on scopolamine-induced amnesia and on delay-interposed short-term memory performance were investigated using an 8-arm radial maze in rats. Scopolamine, a muscarinic antagonist, deteriorated the radial maze performance, while MK-801, an NMDA receptor channel...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)86075-5
更新日期：1997-02-01 00:00:00
abstract：BACKGROUND:As an atypical antipsychotic drug, quetiapine had been approved for bipolar disorder and for adjunctive therapy in major depressive disorder and schizophrenia. Recently quetiapine has been suggested to be a promising pharmacotherapy for alcohol dependence. This study was performed to determine the effects of...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2020.112561
更新日期：2020-05-15 00:00:00
abstract：:Early maternal deprivation (MD) is an animal model of neurodevelopmental stress associated with a variety of abnormalities during adulthood. The present study investigated specific behavioral, neurochemical and neurobiological parameters related to dopaminergic and serotonergic function in adult rats subjected to earl...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2013.01.040
更新日期：2013-05-01 00:00:00
abstract：:Latent inhibition (LI) is a behavioural procedure in which preexposure to a stimulus not followed by reinforcement retards subsequent conditioning to this stimulus when it is paired with reinforcement. Changes in LI thus reflect greater or lesser retardation of learning which essentially implies a potentiation or an a...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.06.018
更新日期：2005-02-10 00:00:00
abstract：:Reactive oxygen species (ROS) and pro-inflammatory cytokines (PIC) are upregulated in post-traumatic stress disorder (PTSD). Histone deacetylase inhibitors (HDACi) modify genetic transcription and can diminish ROS and PIC escalation. They can also modulate levels of neurotransmitters such as catecholamines and seroton...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.03.029
更新日期：2014-07-15 00:00:00
abstract：:The zebrafish (Danio rerio) is emerging as a promising model organism for experimental studies of stress and anxiety. Here we further validate zebrafish models of stress by analyzing how environmental and pharmacological manipulations affect their behavioral and physiological phenotypes. Experimental manipulations inc...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.06.022
更新日期：2009-12-14 00:00:00
abstract：:Systemic administration of apomorphine, angiotensin II, neurotensin and leucine-enkephalin induces emesis in dogs in a dose-dependent fashion. Receptors for Leu-enkephalin and angiotensin II but not apomorphine show receptor desensitization, such that a second systemic administration 5 min after the first is ineffecti...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(84)90220-1
更新日期：1984-03-01 00:00:00
abstract：:Neurotrimin (Ntm) belongs to the IgLON family of cell adhesion molecules with Lsamp, Obcam and kilon that regulate the outgrowth of neurites mostly by forming heterodimers. IgLONs have been associated with psychiatric disorders, intelligence, body weight, heart disease and tumours. This study provides an initial behav...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.09.064
更新日期：2017-01-15 00:00:00
abstract：:Serotonergic (5-HT) drugs are widely used in the clinical management of mood and anxiety disorders. However, it is reported that acute 5-HT treatment elicits anxiogenic-like behavior. Interestingly, the periaqueductal gray (PAG), a midbrain structure which regulates anxiety behavior - has robust 5-HT fibers and recipr...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.07.003
更新日期：2014-10-15 00:00:00
abstract：:Although the involvement of the mTOR (mammalian target of rapamycin) system in memory processes has been reported, information on the effect of rapamycin on spatial learning and memory is limited. It was therefore the aim of the study to show the effect of parenteral rapamycin administration to C57BL/6J mice on perfor...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.01.017
更新日期：2012-04-15 00:00:00
abstract：:The prefrontal cortex (PFC) is known to be involved in associative learning; however, its specific role in acquisition of cued classical conditioning has not yet been determined. Furthermore, the role of regional differences within the PFC in the acquisition of cued conditioning is not well described. These issues wer...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2003.09.014
更新日期：2003-11-30 00:00:00
abstract：:Environmental enrichment (EE) involves enhancing an animal's environment, with the goal of improving animal welfare. Though a well-established discipline, the consequences of EE on behavioural pharmacological tests have not been extensively examined. The purpose of this study was to examine the consequences of EE (or ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.06.015
更新日期：2012-10-01 00:00:00
abstract：:Pigeon hippocampal neurons display two spatial response profiles: location fields frequently at goals, and path fields connecting goals. We recorded from 15 location and six path cells, with color cues positioned near four goal locations. Following color cue rotation, most location cells (12/15) shifted their response...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2007.09.031
更新日期：2008-03-05 00:00:00
abstract：:Growing evidence suggests that testosterone may play a role in the pathophysiology of schizophrenia given that testosterone has been linked to cognition and negative symptoms in schizophrenia. Here, we determine the extent to which serum testosterone levels are related to neural activity in affective processing circui...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.03.020
更新日期：2015-06-01 00:00:00
abstract：:Behavioral and neurobiological parallels between rabbits and humans in eyeblink classical conditioning (EBCC) make this paradigm potentially useful for preclinical and clinical trials. The known involvement of hippocampal pyramidal cells in EBCC in rabbits led us to evaluate the nootropic compound, nefiracetam. In Exp...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)86065-2
更新日期：1997-02-01 00:00:00
abstract：:Clinical research has identified developmental delay and physical malformations in children prenatally exposed to the antiepileptic drug (AED) valproic acid (VPA). However, the early signs of neurodevelopmental deficits, their evolution during postnatal development and growth, and the dose effects of VPA are not well ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.05.023
更新日期：2016-09-15 00:00:00
abstract：BACKGROUND:The predominant view of chronic cocaine use maintains that it causes a broad range of cognitive deficits. However, concerns about the possibly deleterious impact of cocaine on cognitive functioning have yet to be thoroughly vetted. This review addresses the impact of cocaine use on such cognitive domains as ...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2018.04.005
更新日期：2018-08-01 00:00:00
abstract：:Genetically altered mice are available on different background strains. While respective backcrosses are often performed for pragmatic reasons, e.g. references, comparability, or existing protocols, the interaction between the mutations per se and the background strain often remains a neglected factor. The heterozygou...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.07.037
更新日期：2017-09-29 00:00:00
abstract：:The cholinergic hypothesis of memory dysfunction originally proposed that dysfunction of cholinergic neurons in the basal forebrain cholinergic system (BFCS) may be responsible for the memory deficits associated with aging and Alzheimer's disease (AD). This hypothesis directed focus on the BFCS in experimental animal ...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(95)00143-3
更新日期：1996-02-01 00:00:00
abstract：:We review some of the evidence for structural changes in synapses in response to environmental stimulation. These include changes in synapse number, in distribution of presynaptic vesicles, in synaptic bouton size, and complex changes in the shape and size of synaptic contact zones. Increased numbers of postsynaptic p...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(94)00116-w
更新日期：1995-01-23 00:00:00
abstract：:Motor cortex stimulation oriented by functional cortical mapping is used mainly for treating otherwise intractable neurological disorders, however, its mechanism of action remains elusive. Herein, we present a new method for functional mapping of the rat motor cortex using non-invasive transdural electrical stimulatio...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.03.018
更新日期：2009-08-24 00:00:00
abstract：:This study addresses whether or not mild, forced treadmill exercise improves learning and increases neurotrophin levels in the basal forebrain (BF). Neurotrophin deficits in the BF have been implicated in Alzheimer's disease, and physical exercise increases neurotrophins. Aged rats exercised for 7 weeks found the hidd...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2005.11.008
更新日期：2006-04-03 00:00:00
abstract：:Synthetic cathinones share potent sympathomimetic properties with amphetamines due to their shared phenethylamine backbone. Despite recent work focused on understanding the behavioral effects of synthetic cathinones, a systematic comparison of neuropharmacology, behavior, and physiological effects with other stimulant...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112368
更新日期：2020-02-03 00:00:00
abstract：:Rabbits with substantial neocortical lesions were given trace conditioning of the nictitating membrane response over a range of interstimulus intervals (ISIs). Unlike hippocampal lesioned animals, which show deficits in such conditioning, the decorticates were not impaired and they gave greater numbers of conditioned ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(84)90010-x
更新日期：1984-01-01 00:00:00
abstract：:Sleep deprivation (SD) has been reported to induce transient cognitive impairment in functional domains commonly affected in dementia, including memory. Indeed, sleep disturbance has been proposed as an early marker for Alzheimer's disease (AD). SD emulates many aging-related modifications, including important memory ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112066
更新日期：2019-11-05 00:00:00
abstract：:Meditation improves executive functions such as attention and working memory processes. However, it remains unclear to what extent contextual effects contribute to these improvements, since the role of meditation-associated expectations has not been investigated so far. In a randomized, single-blind, deceptive, betwee...
journal_title：Behavioural brain research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bbr.2015.10.012
更新日期：2016-01-15 00:00:00
abstract：:In the USA, the stimulant drug methylphenidate (MPH) is used to treat a large number (2 million or more per year) of children with Attention Deficit Hyperactivity Disorder (ADHD). Although the US FDA approved MPH in the 1960s, the pharmacokinetic (PK) properties of serum concentrations of MPH in children with ADHD wer...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/s0166-4328(01)00433-8
更新日期：2002-03-10 00:00:00
abstract：:The effect of feeding behavior on other behaviors (swimming, crawling and shortening) was investigated in the leech, Hirudo medicinalis. The stimulus locations and intensities required to produce mechanically elicited behaviors were first determined in the non-feeding leech. Stimuli were delivered while the leech was ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)00072-7
更新日期：1998-01-01 00:00:00
