[Possibilities of eradicating the persistent HBsAg carrier state].

Abstract:

:Five HBsAg carriers were examined by clinical, biochemical, radionuclide, immunologic and histomorphologic methods. Different variants of structural and functional relations were established. Attempts were made to eradicate the persistent virus carrierstate with the aid of the antiviral drug virasol, the immunomodulating drug levamisole, nonspecific (BCG vaccine) and specific (original corpuscular vaccine against hepatitis B) immunostimulants. No positive therapeutic effect was obtained. The difficulties and possibilities of a further study into the title problem with due regard for integration mechanisms of infection and prospects of the effective prophylaxis of virus transmission from the mother to the child at birth are discussed.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Farber NA,Ambrozaĭtis AK,Kelli EI,Vygodskiĭ VS,Savitskiĭ GI

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

99-103

issue

11

eissn

0040-3660

issn

2309-5342

journal_volume

56

pub_type

杂志文章
  • [Pulmonary function of patients with bird-breeders' exogenous allergic alveolitis].

    abstract::A total of 59 bird fanciers suffering from alveolitis were examined, of them 23 with alveolitis of bronchitis type, 24 with alveolitis of pneumonic type and 11 alveolitis of fibrosing type. In all 3 variants of a course of alveolitis the obstructive syndrome was the main sign of functional disturbances. Intrapulmonary...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nefedov VB,Shergina EA

    更新日期:1987-01-01 00:00:00

  • [Antinuclear antibodies in Sjögren's disease and syndrome].

    abstract::A study was made of the presence of antinuclear antibodies to Ro, La, nDNA, RNP and Sm in 18 patients with Sjögren's disease (SD) and in 13 patients with Sjögren's syndrome (SS). Anti-Ro and/or anti-La were revealed in 12 SD patients (67%) and in 3 SS patients (23%, P less than 0.05) only. Anti-nDNA and anti-RNP were ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kirtava ZZ,Guseva NG,Vasil'ev VI,Poverennyĭ AM,Ivanova SM

    更新日期:1986-01-01 00:00:00

  • [The clinical prognosis of the complication of peptic ulcer by acute hemorrhage].

    abstract::Clinical parameters have been studied in 45 peptic ulcer patients without and 47 ones with acute hemorrhage. Factors of acute hemorrhage risk in ulcer patients have been specified (old age, long history of the disease, previous hemorrhages, duodenal ulcer localization at the back and upper walls and gastric ulcer loca...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Abrashkina ED

    更新日期:1993-01-01 00:00:00

  • [A mass study of hepatobiliary system function in workers and collective farmers in southern Tadzhikistan].

    abstract::A total of 4085 persons living in the Parkhar District of Kulyab Province of the Tadzhik SSR underwent examination for the cholelithiasis incidence among 3 large groups (Koreans, Tadzhiks and Uzbeks) populating that territory. It has been established that as compared with Tadzhiks and Uzbeks, cholelithiasis turned out...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Mansurov KhKh,Mansurova FKh,Mishunina NA,Asimova DM,Gafarova MA,Belanovskaia LK,Ramazanova ZD

    更新日期:1990-01-01 00:00:00

  • [The state of the great arteries in type 2 diabetes mellitus patients with obstructive sleep apnea syndrome].

    abstract:AIM:To evaluate the impact of hyperglycemia concurrent with obstructive sleep apnea syndrome (OSAS) on endothelial function (EF) and vessel remodeling in patients with Grade 1-2 hypertension. MATERIAL AND METHODS:A total of 101 patients with Grade 1-2 hypertension were examined. A study group (SG) consisted of 74 hype...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh2015871026-30

    authors: Oleynikov VE,Sergatskaya NV,Gusakovskaya LI,Khromova AA

    更新日期:2015-01-01 00:00:00

  • [Rare forms of paraproteinemic hemoblastosis].

    abstract::The paper is concerned with 10 cases of multiple myeloma with myeloid (myeloma-myeloid) splenomegaly and myelemia; 4 cases of chronic subleukemic (or aleukemic) lymphocyte plasma cell leukemia with paraproteinemia G which do not differ in the clinical or morphological picture from Waldenström's macroglobulinemia ("Wal...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Andreeva NE

    更新日期:1984-01-01 00:00:00

  • [The use of the results of current instrumental methods of cardiological examination in the sociomedical expert assessment of patients with rheumatic heart defects].

    abstract::Altogether 103 patients with rheumatic heart disease were examined within different times after prosthetics of heart valves (mitral or aortal). The purpose was to elaborate the principles of applying the data of instrumental methods of cardiological examination to the improvement of disability criteria. The examinatio...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kuz'mishin LE,Komarova LE,Gromova GV

    更新日期:1994-01-01 00:00:00

  • [Reverse diffusion of hydrogen ions and its correlation with acid secretion and proliferative activity of gastric mucosal epithelium in patients with variants of chronic gastritis and peptic ulcer].

    abstract::Eighty-one patients with chronic gastritis and 124 patients with peptic ulcer were examined. It was discovered that in chronic gastritis, the concomitant gastritis included, in patients with peptic ulcer, the degree of enhancement of reverse diffusion of hydrogen ions depended on the intensity of atrophy of the fundal...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Geller LI,Alekseenko SA

    更新日期:1984-01-01 00:00:00

  • [Molecular markers as risk factors for thyroid cancer].

    abstract::Thyroid cancer is the most common malignant tumor of the endocrine system. An increase in the incidence of thyroid cancer has been noted over the past decade, mainly due to papillary cancer. The influence of environmental factors, increased availability of medical care, including sensitive diagnostic tests, such as ul...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/00403660.2019.10.000357

    authors: Rogova MO,Novosad SV,Martirosian NS,Trukhina LV,Petunina NA

    更新日期:2019-10-15 00:00:00

  • [Diagnostic value of clinical electrocardiography indices for recognizing myocardial infarct of the right and left ventricles].

    abstract::The sensitivity, specificity, predictive value and informative value of clinical and electrocardiographic indices were assessed in patients with verified diagnoses of concomitant (17) and isolated left ventricular (23) myocardial infarction. The most informative and specific signs in terms of involvement in the right ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Denidenko BA

    更新日期:1985-01-01 00:00:00

  • [Selective involvement of the gastrointestinal tract in amyloidosis in a female patient with periodic disease and intact kidneys].

    abstract::The authors describe a rare case of amyloidosis in a female patient suffering from periodic disease (PD) for 18 years without any clinico-laboratory signs of renal impairment but with marked clinical, (malabsorption, cachexia), endoscopic, x-ray and other manifestations of gastrointestinal amyloidosis. This case is of...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Arutiunian VM,Eganian GA,Khachatrian VA

    更新日期:1991-01-01 00:00:00

  • Combination therapy is a new standard for treatment of pulmonary arterial hypertension.

    abstract::At present, compelling evidence has been obtained that combined therapy of pulmonary arterial hypertension (PAH) with specific drugs can significantly slow progression of PAH. Therefore, in current guidelines combination therapy is already considered as standard treatment for a significant proportion of patients with ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.26442/terarkh201890372-80

    authors: Avdeev SN,TsarEva NA,Gaisin IR

    更新日期:2018-04-19 00:00:00

  • [The therapeutic potentials of Ditec in bronchial asthma patients].

    abstract::Ditec effects on clinicofunctional status were investigated in 15 patients with mild and moderate atopic bronchial asthma (ABA) aged 20-50 (5 males and 10 females). A single ditec dose had a broncholytic effect along the entire bronchial tree and reduced sensitivity to acetylcholine. Magnesium sulfate (a single dose 3...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Fedoseev GB,Emel'ianov AV,Sinitsina TM,Goncharova VA

    更新日期:1995-01-01 00:00:00

  • [Antihypertensive therapy optimization and endothelial function in patients with gout and chronic urate tubulointerstitial nephritis].

    abstract:AIM:to characterize the markers of endothelial dysfunction and the effect of antihypertensive drugs on them in patients with chronic urate tubulointestinal nephritis (UTIN) and articular gout. SUBJECTS AND METHODS:The study enrolled 81 patients aged 39 to 59 years with gout and urate nephropathy. All the patients were...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Lebedeva MV,Stakhova TIu,Zaĭtseva LI,Selivanova OIu,Severova MM

    更新日期:2010-01-01 00:00:00

  • [Characteristics of erythropoiesis regulation in population living at high altitude].

    abstract:AIM:To study characteristics of iron deficiency anemia (IDA) in native population of high altitude territories. MATERIAL AND METHODS:1300 women living in Tien-Shan areas were examined for serum and erythrocytic ferritins (SF and EF), general iron-binding capacity of the serum, transferrin saturation with iron, transfe...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Makeshova AB,Levina AA,Mamukova IuI,Raimzhanov AR

    更新日期:2004-01-01 00:00:00

  • [Disorders in the hypophysis-adrenal and hypophysis-thyroid systems of patients with acute pneumonia and the ways for their therapeutic correction].

    abstract::Using RIA, 188 patients with acute pneumonia were examined over time for the blood ACTH, cortisol, TTH, T3 and T4 content as well as for T4/T3, TTH/T3 and TTH/T4 correlations. Under discussion are causes, approaches to the prevention and correction of the hormonal disorders revealed in the pituitary-adrenal system in ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Panfilov IuA,Sharonov VG

    更新日期:1990-01-01 00:00:00

  • [Bacterial toxins: old functions, a new use].

    abstract::The paper provides current views on the structure and functional activity of bacterial toxins, clinical use of bacterial lipopolysaccharides and their derivatives as immunostimulators, review investigations on the introduction of the botulinic toxin A in ophthalmological and neurological practice, on production of imm...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Malov VA,Pak SG

    更新日期:1994-01-01 00:00:00

  • [The optimization of instrumental hemofiltration].

    abstract::47 hemofiltration procedures were performed in 10 patients. A self-made balancer based on the volumic hydrodynamics dependent on substitute from filtrate was used. An APD-02 peritoneal dialysis machine served the source of the substitute. It provided change of the concentration and was used for prophylaxis of osmodist...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Sagatovich VA

    更新日期:1997-01-01 00:00:00

  • [The aspects of the problem of systemic vasculitis open to discussion].

    abstract::Some controversial problems in the diagnosis of systemic vasculitis are discussed. The importance of the morphological studies is assessed. The data are provided on the interrelations between skin and systemic vasculitis, on the existence of the local forms of vasculitis, the presence of the crisscross, mixed and comb...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Shilkina NP

    更新日期:1989-01-01 00:00:00

  • [Significance of surfactant proteins in the diagnosis of therapeutic diseases].

    abstract::The lung provides not only respiration, but also the functioning of innate immunity mechanisms. The hydrophilic proteins SP-A and SP-D are responsible for the regulation of the latter. In the literature, there is evidence for elevated serum SP-A and SP-D levels in respiratory diseases accompanied by enhanced mucosal i...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.17116/terarkh2015871115-119

    authors: Kovalkova NA,Ragino YI,Logvinenko NI,Merekina ES,Voevoda MI

    更新日期:2015-01-01 00:00:00

  • [Characterization of the genotypes of patients with Gaucher disease type 1 in the Russian Federation].

    abstract:AIM:To characterize the genotype and genotype-phenotype correlations in patients with Gaucher disease (GD) in the Russian Federation. MATERIALS AND METHODS:One hundred adult patients with GD type 1 were examined. Their clinical study encompassed the evaluation of the severity of osteoarticular lesions from instrumenta...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Lukina KA,Fevraleva IS,Sysoeva EP,Mamonov BE,Sudarikov AB,Lukina EA

    更新日期:2013-01-01 00:00:00

  • [The chemotactic characteristics of the leukocytes and fibroblasts in amyloidosis].

    abstract::Altogether 44 patients with amyloidosis (7 with primary, 24 with secondary and 13 with hereditary associated with periodic disease) and different stages of renal impairment and 32 patients with chronic glomerulonephritis (CGN) (14 with the latent and 18 with the nephrotic form) were examined for chemotactic properties...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Karryeva BCh,Kozlovskiĭ LO,Liashko VN,Samoĭlov DV

    更新日期:1990-01-01 00:00:00

  • [Analysis of factors affecting circulation in the territory of internal carotid artery in arterial hypertension].

    abstract:AIM:To assess carotid blood flow in healthy subjects and hypertensive patients, to specify prognostic significance of factors affecting carotid circulation with use of a multivariate analysis. MATERIAL AND METHODS:Clinical examination, ultrasonic dopplerography of the internal carotid arteries (ICA), echocardiography,...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Rabinovich RM

    更新日期:2008-01-01 00:00:00

  • [Programmed hemodialysis in middle and old age].

    abstract::28 patients treated by programmed hemodialysis (PH) were followed up from 1985 to 1991. All the patients were over 60 years old. 16 patients died within month 1-60 since PH initiation. Overall PH duration for the whole group reached 24.6 +/- 3.58 months. Pretreatment urea and creatinine in plasma of senile patients we...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Mikhaĭlova NA,Ermolenko VM,Naumtseva Si,Tsukerman LI,Sura VV,Denisov AIu

    更新日期:1994-01-01 00:00:00

  • [Avelox efficacy in the treatment of acute purulent rhinosinusitis].

    abstract:AIM:To compare efficacy of avelox systemic antibiotic therapy with and without maxillary puncture in acute purulent rhinosinusitis (ARS). MATERIAL AND METHODS:A total of 40 ARS patients were divided into two groups: puncture was not made in 20 patients of the study group and was made in 20 patients of the control grou...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ivanchenko OA,Chuchueva NG,Lopatin AS

    更新日期:2007-01-01 00:00:00

  • European Registry on the management of Helicobacter pylori infection (Hp-EuReg): analysis of 2360 patients receiving first-line therapy in Russia.

    abstract:AIM:European Registry on the management of Helicobacter pylori infection («Hp-EuReg») - a multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group, conducted in 27 European countries in order to evaluate the real clinical practice of diagnosis and treatment of H. pyl...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,多中心研究

    doi:10.26442/terarkh201890235-42

    authors: Bordin DS,Embutnieks YV,Vologzhanina LG,Il'chishina TA,Voinovan IN,Sarsenbaeva AS,Alekseenko SA,Zaitsev OV,Abdulkhakov RA,Osipenko MF,Livzan MA,Tsukanov VV,Burkov SG,Bakulina NV,Dekhnich NN,Tarasova LV,Plotnikova EY,Mae

    更新日期:2018-02-15 00:00:00

  • Realities and prospects of remote blood pressure monitoring in hypertensive patients.

    abstract::Despite the success in increasing the effectiveness of treatment of arterial hypertension (AH), frequency of achieving target levels of blood pressure (BP) in hypertensive patients and the scope of their regular supervision in most countries of the world, including in the Russian Federation are insufficient. Modern te...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh20189014-8

    authors: Boytsov SA

    更新日期:2018-01-09 00:00:00

  • [Hepatitis C can be cured: will hepatitis B become next?]

    abstract::Chronic hepatitis B (CHB) and C (CHC) are one of the leading causes of cirrhosis and liver cancer with over a million of people dying annually from their consequences. In Russia CHB and CHC morbidity and related mortality show an upward trend. As a result of recent breakthroughs in antiviral therapeutics CHC became a ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.17116/terarkh201789114-13

    authors: Chulanov VP,Zueva AP,Kostyushev DS,Brezgin SA,Volchkova EV,Maleyev VV

    更新日期:2017-01-01 00:00:00

  • [Renal transplantation in recipients with moderate presensitization].

    abstract:AIM:to comparatively assess desensitization schemes with and without plasmapheresis in patients with low presensitization. SUBJECTS AND METHODS:The investigators studied the efficiency of the two desensitization schemes (cascade plasma filtration + intravenous immunoglobulin used in a dose of 100 mg/kg in 19 patients ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh201688867-72

    authors: Vatazin AV,Zulkarnaev AB

    更新日期:2016-01-01 00:00:00

  • [Evaluation of the efficacy of prucalopride (resolor) in the treatment of patients with chronic constipation].

    abstract:AIM:To evaluate the efficacy of the enterokinetic prucalopride (resolor) in patients with chronic constipation. SUBJECTS:The effect of treatment with prucalopride (resolor) in 109 patients with chronic constipation was analyzed. RESULTS:The effect was noted in 82% of the patients; 61 patients were fully satisfied wit...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Osipenko MF,Bikbulatova EA,Skalinskaia MA,Kulygina IuA,Pankova LIu

    更新日期:2013-01-01 00:00:00