Prognosis of skin melanoma with regional node metastases (stage II).

Abstract:

:566 stage-II melanoma patients treated at the National Cancer Institute of Milan, Italy, were analyzed to evaluate the prognosis. Among the criteria considered, four were significantly associated with survival when considered as single factors: growth pattern, levels of invasion, the number of involved lymph nodes, and the extent of metastatic growth. As regards growth pattern, the observed 5-year survival rates were 41.9% for superficial spreading melanoma and 20.5% for nodular melanoma (P = 10(-3)). As regards levels, the 5-year survival rates were as follows: level II, 20.9%; level III, 33.1%; level IV, 43.2%; level V, 10.2% (P = 10(-3)). Patients with a partial node metastasis had 64.5% 10-year survival, while those with extension beyond the capsule had 32.6% 10-year survival (P = 10(-9). Patients with one metastatic node had 43.4% 10-year survival, and patients with three or more positive nodes had 26.0% 10-year survival (P = 10(-9)). Multifactorial analysis shows that growth pattern and extent of node metastases significantly affect survival (P = 10(-2) and P = 10(-4), respectively) while the number of involved nodes turns to borderline P-value (0.051) and the levels are no longer significant (P = 0.4).

journal_name

J Surg Oncol

authors

Cascinelli N,Vaglini M,Nava M,Santinami M,Marolda R,Rovini D,Clemente C,Bufalino R,Morabito A

doi

10.1002/jso.2930250404

subject

Has Abstract

pub_date

1984-04-01 00:00:00

pages

240-7

issue

4

eissn

0022-4790

issn

1096-9098

journal_volume

25

pub_type

杂志文章
  • Is there a role for second-look laparotomy in the management of malignant germ cell tumors of the ovary? Experience at Institut Gustave Roussy.

    abstract::The last two decades have seen great improvements in the management of patients with germ-cell tumors of the ovary. The initial treatment approach includes conservative surgery and cisplatin-based chemotherapy in most cases. At completion of chemotherapy, the role of second-look surgery remains questionable. We retros...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199605)62:1<40::AID-JSO9>3

    authors: Culine S,Lhomme C,Michel G,Leclere J,Duvillard P,Droz JP

    更新日期:1996-05-01 00:00:00

  • Experience of a large series of mastoscopic axillary lymph node dissection.

    abstract:BACKGROUND:Minimally invasive and functional therapy represents an inevitable trend in breast surgery. Improved visualization during mastoscopic axillary lymph node dissection (MALND) realizes a clear exposure of axillary anatomy, but it differs from a general laparoscopic operation. There are some challenges in techni...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21080

    authors: Chengyu L,Jian Z,Xiaoxin J,Hua L,Qi Y,Chen G

    更新日期:2008-08-01 00:00:00

  • Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker.

    abstract:BACKGROUND AND OBJECTIVES:The median of pO2 values in tumor measured by Eppendorf "Histograph" with a needle-type electrode has been used as a prognostic indicator in cancer patients. However, it is not established that a pretreatment measured pO2 value can be used as a universal predictor of local control probability,...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9098(199709)66:1<30::aid-jso7>3

    authors: Nozue M,Lee I,Yuan F,Teicher BA,Brizel DM,Dewhirst MW,Milross CG,Milas L,Song CW,Thomas CD,Guichard M,Evans SM,Koch CJ,Lord EM,Jain RK,Suit HD

    更新日期:1997-09-01 00:00:00

  • Brain, the last fortress of sarcoma: similar dismal outcome but discrepancy of timing of brain metastasis in bone and soft tissue sarcoma.

    abstract:BACKGROUND AND OBJECTIVE:Brain metastasis is a rare but dismal event in sarcomas. However, the pattern of occurrence and the prognostic factors associated with post-brain metastasis survival (PBMS) are not yet well-characterized. METHODS:Sarcoma patients treated at one institute within 10-year period were retrospectiv...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.22011

    authors: Chou YS,Liu CY,Chen WM,Chen TH,Chen PC,Wu HT,Shiau CY,Wu YC,Liu CL,Chao TC,Tzeng CH,Wong TT,Yen CC

    更新日期:2011-12-01 00:00:00

  • Liver resection and ablation for metastatic melanoma: A single center experience.

    abstract:BACKGROUND:The median survival for patients with stage IV metastatic melanoma is usually limited to approximately 1 year. In the case of liver metastasis, resection and ablation can achieve long-term survival. This study aimed to describe the outcomes after liver resection or ablation for metastatic melanoma to the liv...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23929

    authors: Doussot A,Nardin C,Takaki H,Litchman TD,D'Angelica MI,Jarnagin WR,Postow MA,Erinjeri JP,Kingham TP

    更新日期:2015-06-01 00:00:00

  • Spindle cell mucoepidermoid carcinoma of submandibular gland.

    abstract::A malignant tumor of the submandibular gland was found to consist predominately of spindle cell elements that initially suggested a primary sarcoma. Further examination revealed that the spindled malignant cells were derived from a high-grade mucoepidermoid carcinoma. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930310116

    authors: Love GL,Sarma DP

    更新日期:1986-01-01 00:00:00

  • Comparison of clinical outcomes for patients with clinical N0 and pathologic N2 non-small cell lung cancer after thoracoscopic lobectomy and open lobectomy: a retrospective analysis of 76 patients.

    abstract:OBJECTIVE:To compare outcomes between thoracoscopic and thoracotomy lobectomy for patients with cN0-pN2 NSCLC. METHODS:One hundred eighty-two cN0 patients (including 29 pN2) underwent VATS lobectomy between September 2006 and December 2009, and 204 cN0 patients (including 47 pN2) underwent thoracotomy lobectomy betwee...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23104

    authors: Li Y,Wang J

    更新日期:2012-09-15 00:00:00

  • Verrucous carcinoma of the foot.

    abstract::A 50-year-old man presented with verrucous carcinoma on the sole of the foot. This unusual tumor, also called an epithelioma cuniculatum plantare, was successfully treated employing wide surgical excision. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930140407

    authors: Schwartz RA,Burgess GH

    更新日期:1980-01-01 00:00:00

  • Changes in high endothelial venules in lymph nodes after vascularized and nonvascularized lymph node transfer in a murine autograft model.

    abstract:BACKGROUND AND OBJECTIVES:Vascularized lymph node transfer (LNT) is gaining popularity in the treatment of lymphedema. However, it is unclear whether the vascularization of transferred lymph nodes (LNs) contributes to functional improvement. High endothelial venules (HEVs) are specialized vessels that allow lymphocytes...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25365

    authors: Ishikawa K,Funayama E,Maeda T,Hayashi T,Murao N,Osawa M,Ito R,Furukawa H,Oyama A,Yamamoto Y

    更新日期:2019-05-01 00:00:00

  • Current surgical management of in situ cancer of the female breast.

    abstract::Surgical procedures for breast cancer were compared in 468 cases with in-situ and 4,967 cases with invasive lesions. The cases were obtained from the Michigan Cancer Foundation Registry, a Surveillance, Epidemiology, and End Results (SEER) participant, and were incident-resident cases diagnosed from 1973-1978. For sin...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930200207

    authors: Albert S,Belle S,Eckert D,Swanson GM

    更新日期:1982-06-01 00:00:00

  • DNA ploidy and PCNA index in pancreatic lesions producing hyperinsulinemic hypoglycemia.

    abstract::DNA nuclear content and PCNA index (proportion of PCNA reactive cells) have been studied by flow cytometry in eight pancreatic lesions producing hyperinsulinemic hypoglycemia to assess DNA ploidy and tumoral growth fraction. Adult nesidioblastosis had a diploid DNA index, two adenomas were near diploid, and four of th...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930590105

    authors: Losada J,Sarria R,Fernandez Val JF,Lopez Ariztegui MA

    更新日期:1995-05-01 00:00:00

  • Retroperitoneoscopic adrenalectomy: lateral versus dorsal approach.

    abstract:BACKGROUND:For tumours of the adrenal gland different surgical retroperitoneal approaches have been established, including the lateral and the dorsal approach. It is still unclear if the lateral or the dorsal approach should be preferred. PATIENTS AND METHODS:A retrospective comparison between 21 patients who underwen...

    journal_title:Journal of surgical oncology

    pub_type: 信件

    doi:10.1002/jso.20793

    authors: Agha A,von Breitenbuch P,Gahli N,Piso P,Schlitt HJ

    更新日期:2008-01-01 00:00:00

  • Treatment of liver colorectal metastases: role of laparoscopy, radiofrequency ablation, and microwave coagulation.

    abstract::Up to 50% of patients with colorectal cancer will develop metastatic disease in the liver. While surgical extirpation remains the best option for long-term survival, several complementary modalities such as laparoscopy, radiofrequency ablation, and microwave coagulation have gained wide acceptance as primary and adjun...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21720

    authors: Rocha FG,D'Angelica M

    更新日期:2010-12-15 00:00:00

  • The prognostic value of grade of regression and oncocytic change in rectal adenocarcinoma treated with neo-adjuvant chemoradiotherapy.

    abstract:BACKGROUND:Pathological staging and regression grading may affect the clinical outcome in rectal carcinoma patients treated with neoadjuvant chemoradiation (NACRT). Oncocytic change (OC) has also been described in the residual tumor. This study assesses the correlation of degree of pathological response and OC with cli...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.22073

    authors: Roy P,Serra S,Kennedy E,Chetty R

    更新日期:2012-02-01 00:00:00

  • Management and outcomes among patients with mixed hepatocholangiocellular carcinoma: A population-based analysis.

    abstract:BACKGROUND:We sought to define the management of mixed hepatocellular carcinoma-intrahepatic cholangiocarcinoma (HCC-ICC) as well as characterize short- and long-term outcomes of patients with mixed HCC-ICC. METHODS:Patients diagnosed with HCC-ICC, HCC, or ICC between 2004 and 2015 were identified from the National Ca...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25331

    authors: Spolverato G,Bagante F,Tsilimigras D,Ejaz A,Cloyd J,Pawlik TM

    更新日期:2019-03-01 00:00:00

  • Malignant pheochromocytoma and paraganglioma: a population level analysis of long-term survival over two decades.

    abstract:BACKGROUND AND OBJECTIVES:Pheochromocytoma (PHEO) and paraganglioma (PGL) are rare tumors. Aims of this study were to describe and to compare demographic, clinical, pathologic, and survival characteristics of malignant PHEO and PGL. METHODS:Patients were identified in SEER, 1988-2009. Analyses included chi-square, ANO...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23297

    authors: Goffredo P,Sosa JA,Roman SA

    更新日期:2013-05-01 00:00:00

  • Patient generated health data and electronic health record integration in oncologic surgery: A call for artificial intelligence and machine learning.

    abstract::In this review, we aim to assess the current state of science in relation to the integration of patient-generated health data (PGHD) and patient-reported outcomes (PROs) into routine clinical care with a focus on surgical oncology populations. We will also describe the critical role of artificial intelligence and mach...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.26232

    authors: Melstrom LG,Rodin AS,Rossi LA,Fu P Jr,Fong Y,Sun V

    更新日期:2021-01-01 00:00:00

  • Carcinoma of the larynx.

    abstract::Six hundred sixty-eight patients with tumours of the larynx were treated by radiotherapy. The patients had stage T1 N0 M0 to T4 N3 M0 disease. Patients with T1 N0 M0 disease (273) had an excellent long-term survival (90%) as did those with T2 N0 M0 disease (142), whose 5-year survival was 70%. Patients with more advan...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930350402

    authors: Robertson AG,Boyle P,Deuchars F,Robertson C

    更新日期:1987-08-01 00:00:00

  • Pharmacokinetics of cis-diamminedichloroplatinum (II) given as low-dose and high-dose infusions.

    abstract::A pharmacokinetic analysis of cis-diamminedichloroplatinum (II) (DDP) was conducted comparing low-dose daily bolus infusions, and high-dose drip infusions. Eight patients with gastric cancer were treated with low-dose daily bolus infusions of DDP to a total daily dose of 75 mg/m2 bid for 5 days. Four patients with eso...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199606)62:2<135::AID-JSO10

    authors: Kurihara N,Kubota T,Hoshiya Y,Otani Y,Ando N,Kumai K,Kitajima M

    更新日期:1996-06-01 00:00:00

  • Macrophage migration inhibitory factor contributes angiogenesis by up-regulating IL-8 and correlates with poor prognosis of patients with primary nasopharyngeal carcinoma.

    abstract:BACKGROUND AND OBJECTIVES:We aim at the association of macrophage migration inhibitory factor (MIF) with neovascularization and survival of nasopharyngeal carcinoma (NPC), and determine whether MIF is a valuable prognostic predictor for NPC patients. METHODS:One hundred and forty one cases of NPC and 25 normal tissues...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21728

    authors: Liao B,Zhong BL,Li Z,Tian XY,Li Y,Li B

    更新日期:2010-12-01 00:00:00

  • Growth index, assessed with Ki-67 and ssDNA labeling; a significant prognosticator for patients undergoing curative resection for hepatocellular carcinoma.

    abstract:BACKGROUND AND OBJECTIVES:The aggressiveness and greater malignant potential of cancers are characterized by several biological phenomena such as accelerated growth invasiveness, and the ability to form distant metastasis. Thus, knowledge of such biological difference may be a more accurate prognosticator for cancer pa...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20309

    authors: Morinaga S,Ishiwa N,Noguchi Y,Yamamoto Y,Rino Y,Imada T,Takanashi Y,Akaike M,Sugimasa Y,Takemiya S

    更新日期:2005-12-15 00:00:00

  • Biological significance of the maximum standardized uptake values on positron emission tomography in non-small cell lung cancer.

    abstract:BACKGROUND:The 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) has recently become an important non-invasive tool for the diagnosis and staging in several cancers. The standardized uptake value (SUV) of primary tumor has been reported to relate to cancer progression and prognosis, however, biolo...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21386

    authors: Takenaka T,Yano T,Ito K,Morodomi Y,Miura N,Kawano D,Shoji F,Abe K,Honda H,Maehara Y

    更新日期:2009-12-15 00:00:00

  • Barriers to rehabilitation following surgery for primary breast cancer.

    abstract::Surgery is a mainstay of primary breast cancer therapy. Alterations in surgical technique have reduced normal tissue injury, yet pain and functional compromise continue to occur following treatment. A tenuous evidence base bolstered by considerable expert opinion suggests that early intervention with conventional reha...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.20782

    authors: Cheville AL,Tchou J

    更新日期:2007-04-01 00:00:00

  • Importance of margin width in breast-conserving treatment of early breast cancer.

    abstract:BACKGROUND AND METHOD:The association between margin width and ipsilateral breast tumour recurrence (IBTR, defined as invasive recurrence) was investigated in a population-based nationwide cohort of 11,900 patients undergoing breast-conserving therapy for invasive cancer. RESULTS:The median follow-up was 4.9 years. Th...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24224

    authors: Bodilsen A,Bjerre K,Offersen BV,Vahl P,Amby N,Dixon JM,Ejlertsen B,Overgaard J,Christiansen P

    更新日期:2016-05-01 00:00:00

  • Antibody to the AIDS virus in Kaposi's sarcoma in Nigeria.

    abstract::The present study has investigated whether Kaposi's sarcoma (KS) in Nigeria is associated with infection with the AIDS virus variously called human T-cell lymphotropic virus type III (HTLV-III), lymphadenopathy/AIDS virus (LAV), and AIDS-associated retrovirus (ARV). Serum samples from 40 KS patients, 30 patients with ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930370303

    authors: Otu AA

    更新日期:1988-03-01 00:00:00

  • Nutritional status in advanced upper gastrointestinal cancer.

    abstract::Fifty-four patients with advanced upper gastrointestinal cancer were assessed for their nutritional status prior to any form of therapy. Anthropometric parameters--weight loss, arm muscle circumference, skin-fold thickness--and biochemical parameters--serum albumin and delayed cutaneous hypersensitivity reactions to p...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930290417

    authors: Singh G,Khanna NN

    更新日期:1985-08-01 00:00:00

  • Breast-specific factors determine cosmetic outcome and patient satisfaction after breast-conserving therapy: Results from the randomized COBALT study.

    abstract:BACKGROUND AND OBJECTIVES:To identify breast-specific factors and the role of tumor, treatment, and patient-related items in influencing patient opinion on cosmesis and satisfaction after breast-conserving therapy (BCT). METHODS:Data from the randomized COBALT study was used. At 3, 12, and 36 months, 128 patients with...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jso.25012

    authors: Volders JH,Negenborn VL,Haloua MH,Krekel NMA,Jóźwiak K,Meijer S,van den Tol PM

    更新日期:2018-04-01 00:00:00

  • Adjuvant chemotherapy after neoadjuvant chemoradiation and curative resection for rectal cancer: is it necessary for all patients?

    abstract:BACKGROUND:The benefit of adjuvant chemotherapy for patients with locally advanced rectal cancer who have received neoadjuvant concurrent chemoradiation therapy (CCRT) and undergone curative resection remains unclear. METHODS:This study was a retrospective review of prospectively collected data. Patients with locally ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23835

    authors: Jung KU,Kim HC,Park JO,Park YS,Park HC,Choi DH,Cho YB,Yun SH,Lee WY,Chun HK

    更新日期:2015-03-15 00:00:00

  • Inguinal canal as an anatomic sanctuary site of relapse in peritoneal carcinomatosis previously treated with intraperitoneal chemotherapy.

    abstract::Early postoperative intraperitoneal chemotherapy (EPIC) and intraoperative peritoneal hypertermic chemotherapy (IPHC) are used in addition with cytoreductive surgery to treat with curative intent peritoneal carcinomatosis arising from colorectal adenocarcinomas. Three patients with such a disease were treated with per...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20267

    authors: Liberale G,Elias D,Sideris L,Lasser P,Malka D,Sabourin JC,Pocard M

    更新日期:2005-07-01 00:00:00

  • Safety of rectum anastomosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

    abstract:BACKGROUND AND OBJECTIVES:In highly selected patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) can be an aggressive but worthwhile treatment regimen. Resection of the rectosigmoid is frequently performed with CRS. The aim of the study wa...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25189

    authors: von Breitenbuch P,Piso P,Schlitt HJ

    更新日期:2018-09-01 00:00:00