Bromocriptine and norethisterone in the treatment of premenstrual syndrome.

Abstract:

:Thirty-six women suffering from premenstrual syndrome were treated with bromocriptine or norethisterone in a randomized placebo-controlled double-blind study. Bromocriptine decreased breast engorgement and irritability (P less than .01) and also decreased the total score of all symptoms (P less than .05). Weight gain during the luteal phase was smaller (P less than .05) during bromocriptine than during placebo treatment. Norethisterone treatment alleviated (P less than .05) breast tenderness. Changes in hormonal parameters and liver function tests during bromocriptine treatment were minimal, whereas norethisterone decreased serum levels of luteinizing hormone (P less than .01), follicle-stimulating hormone (P less than .001), and progesterone (P less than .05), while increasing the serum level of prolactin (P less than .01) and gamma-glutamyltranspeptidase activity (P less than .05). Serum levels of cholic acid and chenodeoxycholic acid remained unchanged during both therapies. Bromocriptine treatment brought about side effects in 6 and norethisterone in 3 women. At the doses used, bromocriptine appears more efficient than norethisterone with regard to premenstrual symptoms, although norethisterone is better tolerated.

journal_name

Obstet Gynecol

authors

Ylöstalo P,Kauppila A,Puolakka J,Rönnberg L,Jänne O

subject

Has Abstract

pub_date

1982-03-01 00:00:00

pages

292-8

issue

3

eissn

0029-7844

issn

1873-233X

journal_volume

59

pub_type

临床试验,杂志文章,随机对照试验
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    authors: Mark SP,Croughan-Minihane MS,Kilpatrick SJ

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  • Occult Uterine Sarcoma and Leiomyosarcoma: Incidence of and Survival Associated With Morcellation.

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    更新日期:2016-01-01 00:00:00

  • Maximal exercise testing in late gestation: fetal responses.

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    authors: MacPhail A,Davies GA,Victory R,Wolfe LA

    更新日期:2000-10-01 00:00:00

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    journal_title:Obstetrics and gynecology

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    doi:

    authors: Dorfman SG,Dillaplain RP,Gambrell RD Jr

    更新日期:1979-03-01 00:00:00

  • Assessing fetal lung maturation by the foam stability index test.

    abstract::An assay has been developed and evaluated that quantifies the surface tension lowering ability of amniotic fluid surfactant. The formation of stable foam following vigorous shaking of amniotic fluid was evaluated by the addition of various amounts of dipalmitoyl lecithin in a solution of ethanol and saline and by fine...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Sher G,Statland BE,Freer DE,Kraybill EN

    更新日期:1978-12-01 00:00:00

  • Cephalothoracopagus (Janiceps) twinning.

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    pub_type: 杂志文章

    doi:

    authors: Wedberg R,Kaplan C,Leopold G,Porreco R,Resnik R,Benirschke K

    更新日期:1979-09-01 00:00:00

  • Thrombocytopenia in two patients treated with low-dose heparin.

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    doi:

    authors: Galle PC,Muss HB,McGrath KM,Stuart JJ,Homesley HD

    更新日期:1978-07-01 00:00:00

  • Amniotic fluid components as determinants of fetal maturity.

    abstract::In order to evaluate the most reliable means of determining fetal maturity, six amniotic fluid components were analyzed from 99 women who were 22 to 40 weeks pregnant. The six parameters investigated were: amylase activity the lecithin to sphingomyelin (L/S) ratio, percentage of fat cells, and the concentrations of pr...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-197507000-00014

    authors: Fernadez De Castro A,Usategui-Gomez M,Spellacy WN

    更新日期:1975-07-01 00:00:00

  • Early fetal movement: a real-time ultrasound study.

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    pub_type: 杂志文章

    doi:

    authors: Shawker TH,Schuette WH,Whitehouse W,Rifka SM

    更新日期:1980-02-01 00:00:00

  • Hypoglycemia in pregnancy secondary to a non-islet cell tumor of the pleura and ectopic insulin-like growth factor II hormone production.

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    doi:10.1016/0029-7844(94)00313-3

    authors: Schweichler M,Hennessey JV,Cole P,Perdue JF,Le Roith D

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    pub_type: 杂志文章

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    authors: Rosenberg AM,Bingham MC,Fong KC

    更新日期:1986-10-01 00:00:00

  • Perinatal and neonatal outcome and late pulmonary sequelae in infants born after preterm premature rupture of membranes.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

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    更新日期:1998-09-01 00:00:00

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Minkoff H,Schaffer RM,Delke I,Grunebaum AN

    更新日期:1985-03-01 00:00:00

  • Chronic Ureaplasma urealyticum amnionitis associated with abruptio placentae.

    abstract::Ureaplasma urealyticum is a common inhabitant of the lower genital tract of women. It is unclear whether or not the microorganism plays a role in provoking spontaneous abortion. Reported is a U urealyticum infection of placenta and amniotic fluid in an immunologically competent host resulting in abruptio placentae and...

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    doi:

    authors: Foulon W,Naessens A,Dewaele M,Lauwers S,Amy JJ

    更新日期:1986-08-01 00:00:00

  • Forecasting the prevalence of pelvic floor disorders in U.S. Women: 2010 to 2050.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

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    更新日期:2009-12-01 00:00:00

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    pub_type: 杂志文章,评审

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    更新日期:1981-11-01 00:00:00

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    authors: Dini MM,Jafari K,Faiferman I

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    更新日期:2007-06-01 00:00:00

  • Neonatal cranial osteomyelitis: a complication of fetal monitoring.

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    authors: Perry CP,Harris RE,DeLemos RA,Null DM Jr

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    doi:

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    更新日期:1991-08-01 00:00:00

  • Presumed antepartum amniotic fluid embolism.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

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    journal_title:Obstetrics and gynecology

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    doi:

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  • Let's get rid of the term "Braxton Hicks contractions".

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

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  • Elective Female Genital Cosmetic Surgery: ACOG Committee Opinion Summary, Number 795.

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    pub_type: 杂志文章,实务指引

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