Presumed antepartum amniotic fluid embolism.

Abstract:

BACKGROUND:Amniotic fluid embolism is seldom recognized in nonperipartum patients. The pathophysiology is uncertain and diagnosis imprecise, making management after stabilization difficult. CASE:A 37-year-old woman at 28 weeks' gestation presented with signs and symptoms consistent with amniotic fluid embolism including disseminated intravascular coagulopathy. A ventilation-perfusion scan demonstrated unmatched perfusion defects, but other radiographic studies were negative; the patient was treated with heparin. Four days after presentation she had spontaneous rupture of membranes followed by hypoxemia, necessitating cesarean delivery. A pulmonary arteriogram after the operation showed multiple filling defects; the patient was discharged on warfarin. CONCLUSION:Amniotic fluid embolism is a difficult diagnosis to make, at best. Anticoagulation may be a therapeutic option.

journal_name

Obstet Gynecol

authors

Kent KJ,Cooper BC,Thomas KW,Zlatnik FJ

doi

10.1016/s0029-7844(03)00630-6

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

493-5

issue

3

eissn

0029-7844

issn

1873-233X

pii

S0029784403006306

journal_volume

102

pub_type

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