Abstract：
:We examined the release in vitro of tumor necrosis factor-alpha (TNF-alpha) by peritoneal macrophages and peripheral blood monocytes following incubation with toxic shock syndrome toxin-1 (TSST-1). We obtained peritoneal macrophages from 22 women at laparoscopy and peripheral blood monocytes from four healthy women during both the midfollicular and midluteal phases of the menstrual cycle. The samples were incubated for 24 hours at 37 C with 10(-2)-10(4) ng/mL of TSST-1 or 10(4) ng/mL of bacterial endotoxin. Tumor necrosis factor-alpha activity was determined with a bioassay using an actinomycin D-sensitized WEHI-164 murine fibrosarcoma cell line. Twenty-four-hour incubation with TSST-1 resulted in a dose-dependent release of TNF-alpha by both peritoneal macrophages (maximal response 554 +/- 97 U of activity) and peripheral blood monocytes (maximal response 478 +/- 81 U of activity). We observed enhanced TNF-alpha release by peritoneal macrophages from women with endometriosis, compared with those without endometriosis, at a concentration of 10(4) ng/mL of TSST-1 (704 +/- 134 versus 354 +/- 103 U of activity; P less than .05). These data support the theory that the metabolic and physiologic derangements of perimenstrual toxic shock syndrome may be partially mediated by TNF-alpha released by peritoneal macrophages as a result of exposure to TSST-1.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Buyalos RP,Rutanen EM,Tsui E,Halme Jsubject
Has Abstractpub_date
1991-08-01 00:00:00pages
182-6issue
2eissn
0029-7844issn
1873-233Xjournal_volume
78pub_type
杂志文章abstract：OBJECTIVE:To assess the risk of maternal parvovirus B19 infection from exposure to various sources and the fetal morbidity of those infections. METHODS:We obtained demographic and occupational information about pregnant women exposed to sources of B19 and about the nature and duration of the exposures. We performed se...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(97)00701-1
更新日期：1998-03-01 00:00:00
abstract：:Severe fetal hydrops was diagnosed at 34 weeks' gestation. Funipuncture revealed a normal 46,XX karyotype and a hematocrit of 20%. Cesarean delivery was performed. Neonatal blood testing showed blood type B positive, positive direct and indirect Coombs, and an anti-B antibody titer of 1:64. The maternal blood group wa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:Danazol is a synthetic steroid with antigonadotropic properties useful in treating endometriosis, especially in young infertile women. Prior to its availability for clinical use in September 1976, thyroid function studies other than thyroid-stimulating hormone (TSH), which was normal, had not been reported. Soon after...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198003000-00028
更新日期：1980-03-01 00:00:00
abstract：:Although there are numerous medical treatments for menorrhagia, in many instances neither the precise diagnosis nor the response to therapy have been assessed objectively. Menorrhagia (menstrual blood loss more than 80 mL per cycle) was diagnosed objectively in 32 (44%) of 72 women with a subjective complaint of heavy...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVE:To evaluate pregnancy outcome among women with isolated polyhydramnios at admission for labor at or beyond 34 weeks of gestation. METHODS:Retrospective cohort study at a tertiary medical center between 2007 and 2012. Isolated polyhydramnios was defined as amniotic fluid index (AFI) greater than 25 cm at admi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000740
更新日期：2015-04-01 00:00:00
abstract：:The dramatic reduction in perinatal morbidity and mortality over the last decade has not been accompanied by any diminution in the incidence of cerebral palsy. We investigated retrospectively the relationship of certain perinatal events to the subsequent development of cerebral palsy in 75 infants. Cerebral palsy occu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1988-06-01 00:00:00
abstract：:Dating of maturity of the endometrium by histologic examination was correlated with four methods of ovulation detection in 13 cycling parous women. Histologic dating was assessed independently by two pathologists and correlated with the postovulatory duration as determined by daily transvaginal ultrasound scanning, se...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Thirty-six women, treated with radical hysterectomy (Piver types III-IV) plus systematic para-aortic and pelvic lymphadenectomy for cervical carcinoma, underwent serial postoperative ultrasound examinations to determine the incidence of lymphocele and the therapeutic efficacy of percutaneous catheter drainage. Pelvic ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:To describe the relations between body mass index (BMI; kg/m(2)), weight gain, and incident urinary incontinence in middle-aged women. METHODS:This was a prospective study in the Nurses' Health Study II. Participants reported their weight at age 18 years, and current weight and height in 1989; weight was upd...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000270121.15510.57
更新日期：2007-08-01 00:00:00
abstract：:The management of polycystic ovarian disease in women not desiring pregnancy is controversial. To avoid the progressive androgenic effects on peripheral target organs, some advocate the use of oral contraceptives. This study reports the effects of a preparation with 50 micrograms ethinyl estradiol and 2 mg cyproterone...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：OBJECTIVE:To determine the opinions of obstetrics and gynecology residency program directors regarding the Residency Review Committee mandate, requires 6 months of primary care training in obstetrics and gynecology. METHODS:A ten-question survey was mailed to the 272 accredited obstetrics and gynecology programs in th...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(97)00600-5
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Bombay blood type is among the rarest in the world and is associated with anti-H antibodies. These antibodies cause severe hemolysis when exposed to any blood product except Bombay and have been reported to cause hemolytic disease of the newborn. CASE:A primigravid woman with Bombay blood type received eryt...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3181f738f3
更新日期：2011-02-01 00:00:00
abstract：:Levels of five antibiotics used in treating chorioamnionitis were measured in maternal and cord blood and placenta. Ampicillin provided the highest ratio of cord to maternal blood (0.71). Gentamicin was also relatively high in this respect and also had the highest placenta to maternal blood ratio (3.97). Based on thes...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：:A case of a primary retroperitoneal mucinous cystadenocarcinoma of ovarian type found at laparotomy in the presence of two normal ovaries is described. Careful examination of the tumor showed no evidence of ovarian tissue in the wall. The appearance of this tumor could be traced from areas of benign mucinous cystadeno...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：OBJECTIVE:To estimate receipt of recommended gynecologic care, including cancer screening and menstrual care, among women with Down syndrome in the United States. METHODS:We conducted a retrospective cohort study of women participating in DS-Connect, the National Institute of Health's registry of women with Down syndr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003997
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Cortical blindness is characterized by loss of vision in the presence of intact anterior visual pathways. Anton syndrome, a form of anosognosia, is a rare complication of cortical blindness involving compromise of the visual association centers, with resulting patient denial of blindness. Both syndromes have...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(97)00718-7
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:To compare sexual function in women with and without uterovaginal prolapse and urinary incontinence. METHODS:Eighty women with prolapse and with or without incontinence and 30 continent women without prolapse completed questionnaires assessing sexual function and underwent a physical examination. RESULTS:Wo...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(94)00434-F
更新日期：1995-04-01 00:00:00
abstract：:Five hundred and fifty six women with invasive epithelial ovarian carcinoma were assessed for postoperative treatment between 1966 and 1976. The records of this group were reviewed retrospectively. Sixteen characteristics of the patient and tumor were analyzed for prognostic significance by univariate and multivariate...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1985-02-01 00:00:00
abstract：:A follow-up study of more than 65,000 healthy women aged 15 to 44 was conducted to assess the association between oral contraceptive use and thromboembolism, stroke, or nonfatal myocardial infarction from 1980 through 1982 at Group Health Cooperative of Puget Sound. A positive association existed between current oral ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:A well-developed corpus luteum was found at autopsy in a premature infant who died 26 hours post partum. Intrauterine pituitary-gonadal development and regulation are briefly reviewed and a possible mechanism of intrauterine fetal ovulation is presented. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-04-01 00:00:00
abstract：OBJECTIVE:To examine cigarette smoking as a risk factor for different types of epithelial ovarian cancer. METHODS:We used data from the Cancer and Steroid Hormone Study, a multicenter, population-based, case control investigation. Cases were 447 women aged 20-54 years with diagnoses of epithelial ovarian cancer. Contr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/s0029-7844(99)00531-1
更新日期：2000-02-01 00:00:00
abstract：:Eighteen patients with mesonephroid ovarian carcinoma were investigated. Typical findings for the mesonephroid tumors were abundant extracellular an some intracellular neutral mucin mixed with sulfate and carboxyl groups, and large amounts of glycogen, especially in clear cells. The latter observation is considered to...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：OBJECTIVE:To estimate the change in indications for scheduled deliveries during the Ohio Perinatal Quality Collaborative's initiative to decrease scheduled deliveries for nonmedical indications before 39 weeks of gestation. METHODS:Documented indications for scheduled deliveries between 36 0/7 and 38 6/7 weeks were ca...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e318260d9b2
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To estimate whether antenatal dietary interventions restrict maternal weight gain in obese pregnant women without compromising newborn birth weight. DATA SOURCES:PubMed and Cochrane Controlled Trials Register were searched using free-text search terms: pregnancy, obesity, overweight, dietary intervention, li...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,meta分析,评审
doi：10.1097/AOG.0b013e3182396bc6
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To compare a "no touch" approach to diagnostic hysteroscopy without anesthesia with traditional diagnostic hysteroscopy after intracervical injection of mepivacaine hydrochloride 3%. METHODS:A total of 130 women undergoing diagnostic hysteroscopy were included in the study and were randomized, using a comput...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1097/01.AOG.0000227750.93984.06
更新日期：2006-08-01 00:00:00
abstract：:A single-transducer mechanical sector scanner was used to examine the first-trimester fetus. Fifty-six examinations of 31 patients demonstrated an orderly developmental progression of fetal activity beginning with beating of the fetal heart (7 weeks), progressing to fetal trunk movement (8 weeks), and culminating in i...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：OBJECTIVE:To identify smartphone menstrual cycle tracking applications (apps) and evaluate their accuracy, features, and functionality. METHODS:In this systematic evaluation, we searched the Apple iTunes store for free menstrual cycle tracking apps for patient use. We considered an application accurate if menstrual cy...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001444
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:To investigate the value of the combined use of vaginal ultrasonography and endometrial sampling in the office for the diagnosis of endometrial disease in postmenopausal women. METHODS:One hundred forty consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytolog...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/0029-7844(94)00421-9
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the accuracy of the diagnosis of presumed ectopic pregnancy. METHODS:This was a retrospective cohort analysis at a tertiary care medical center. The patient population was composed of 1) clinically stable pregnant women with human chorionic gonadotropin (hCG) above 2000 mIU/mL and no evidence of ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(02)02142-7
更新日期：2002-09-01 00:00:00
abstract：:Insulin-dependent diabetic women without adequate glucose control have a higher spontaneous abortion rate when compared with the general population. The present study examined whether the increased rate of spontaneous abortions in insulin-dependent diabetic women was associated with poor glycemic control in the early ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198609000-00015
更新日期：1986-09-01 00:00:00
