Biochemical and biophysical studies of isolated horizontal cells from the teleost retina.

Abstract:

:Neurons in the vertebrate retina are interconnected by a complex network of chemical and electrical synapses which make it difficult to study the intrinsic biochemical and biophysical properties of individual cells. During the past decade, enzymatic methods have been developed for dissociating adult retinas into viable and readily identifiable single cells. Using this preparation, we and other investigators have studied the physiological and biochemical properties of several classes of isolated retinal cells. In particular, we have shown that a type of retinal interneuron, the GABA-ergic horizontal cell of teleost retinas, may be an excellent model system for examining the intrinsic membrane properties as well as the cellular mechanisms regulating GABA uptake, synthesis and release from an identified CNS neuron.

journal_name

Vision Res

journal_title

Vision research

authors

Lam DM,Ayoub GS

doi

10.1016/0042-6989(83)90090-1

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

433-44

issue

4

eissn

0042-6989

issn

1878-5646

pii

0042-6989(83)90090-1

journal_volume

23

pub_type

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