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The unique chemistry of benzoxaboroles: current and emerging applications in biotechnology and therapeutic treatments.

Abstract：

:Benzoxaboroles have garnered much attention in recent years due to their diverse applications in bio-sensing technology, material science, and therapeutic intervention. Part of the reason arises from the benzoxaboroles' unique chemical properties, especially in comparison to their acyclic boronic acid counterparts. Furthermore, the low bio-toxicity combined with the high target specificity associated with benzoxaboroles make them very attractive as therapeutic agents. Herein, we provide an updated summary on the current knowledge of the fundamental chemical reactivity of benzoxaboroles, followed by highlighting their major applications reported to date.

journal_name

Bioorg Med Chem

journal_title

Bioorganic & medicinal chemistry

authors

Liu CT,Tomsho JW,Benkovic SJ

doi

10.1016/j.bmc.2014.04.065

subject

Has Abstract

pub_date

2014-08-15 00:00:00

pages

4462-73

issue

16

eissn

0968-0896

issn

1464-3391

pii

S0968-0896(14)00339-3

journal_volume

22

pub_type

杂志文章,评审

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