Serum copper and zinc concentration in premature and small-for-date infants.

Abstract:

:Serum copper (Cu) and zinc (Zn) concentrations were measured in neonates with an appropriate birth weight for gestational age (AGA) and in small-for-gestational age infants. At 7 days of age, there was a positive correlation between serum Cu concentration and gestational age (GA) (r = 0.63; P < 0.001) and a negative correlation between Zn concentration and GA (r = 0.62; P < 0.01). At 7 days of age, the mean (+/- S.E.) concentrations in AGA full-term infants (Cu, 79 +/- 8 microgram/dl; Zn, 84 +/- 4) were similar to those in small-for-gestational age, full-term infants (Cu, 78 +/- 6 microgram/dl; Zn, 85 +/- 12). In preterm infants, there was also no difference between AGA and small-for-gestational age infants. In 23 AGA infants with a birth weight of less than 1500 g, serum Cu concentration increased from 51 +/- 7 microgram/dl at the age of 7 days to 86 +/- 7 microgram/dl at the age of 60 days (paired t-test: P < 0.05) whereas serum Zn concentration decreased from 149 +/- 9 to 91 +/- 5 microgram/dl (P < 0.01). A positive correlation was found between serum Zn concentration and daily intake of Zn (n = 39; r = 0.3458; P < 0.05), but no correlation was found for serum Cu concentration. The evolution of serum Cu and Zn concentration with total age (GA + postnatal age) in the infants with a low birth weight (i.e., < 1500 g) was similar to the evolution with GA.

journal_name

Pediatr Res

journal_title

Pediatric research

authors

Sann L,Rigal D,Galy G,Bienvenu F,Bourgeois J

doi

10.1203/00006450-198009000-00005

subject

Has Abstract

pub_date

1980-09-01 00:00:00

pages

1040-6

issue

9

eissn

0031-3998

issn

1530-0447

journal_volume

14

pub_type

杂志文章
  • Autoregulation of cerebral blood flow in the preterm fetal lamb.

    abstract::The purpose of the present study was to determine if autoregulation of cerebral blood flow (CBF) is present in the preterm fetal lamb and, if present, to measure the range of mean arterial blood pressure over which autoregulation exists. Thirty-seven measurements of CBF were made in seven preterm fetal lambs (118-122 ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198502000-00001

    authors: Papile LA,Rudolph AM,Heymann MA

    更新日期:1985-02-01 00:00:00

  • Heart rate turbulence in children--age and heart rate relationships.

    abstract::Heart rate turbulence (HRT) is a chronotropic response of the sinus heart rhythm to ventricular premature beat (VPB). Children show decreasing heart rate together with the maturation of the autonomic nervous system. The aim of the research was to assess the relationship between HRT parameters, age, and heart rate and ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181598836

    authors: Kowalewski M,Alifier M,Bochen D,Urban M

    更新日期:2007-12-01 00:00:00

  • Differential effects of glucocorticoids and mineralocorticoids on the mRNA expression of colon ion transporters in infant rats.

    abstract::Several epithelial ion transporters are developmentally regulated in the preweaning period, at the time when the circulating levels of glucocorticoid and mineralocorticoid hormones increase. The specific role of glucocorticoids and mineralocorticoids in the maturation of epithelial ion transport is still disputed. In ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199508000-00005

    authors: Wang ZM,Yasui M,Celsi G

    更新日期:1995-08-01 00:00:00

  • Frequency, tidal volume, and mean airway pressure combinations that provide adequate gas exchange and low alveolar pressure during high frequency oscillatory ventilation in rabbits.

    abstract::We studied healthy and saline lavaged rabbits during high frequency oscillatory ventilation to determine what combination of frequency (f), tidal volume (Vt), and mean airway pressure (Paw) produced the lowest peak-to-peak alveolar pressure amplitude (Palv) and physiologic blood gas tensions. Sinusoidal volume changes...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199001000-00018

    authors: Kamitsuka MD,Boynton BR,Villanueva D,Vreeland PN,Frantz ID 3rd

    更新日期:1990-01-01 00:00:00

  • The physiologic development of fetuin-a serum concentrations in children.

    abstract::Fetuin-A prevents tissue calcification by forming soluble complexes with calcium and phosphate. A pathological depletion of serum fetuin-A has been observed in children on dialysis or after renal transplantation but knowledge on physiologic age-related changes in serum fetuin-A is limited. We prospectively evaluated s...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181bc3f60

    authors: Häusler M,Schäfer C,Osterwinter C,Jahnen-Dechent W

    更新日期:2009-12-01 00:00:00

  • Effect of low dose dopamine on hemodynamic and renal function in children.

    abstract::The purpose of the study was to investigate the effect of low doses of dopamine in children. Fourteen cases were studied after open heart surgery. Cardiac output and renal parameters were determined under baseline conditions and under continuous infusion of dopamine 2.5 and 5 micrograms/kg/min. During the control peri...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198909000-00009

    authors: Girardin E,Berner M,Rouge JC,Rivest RW,Friedli B,Paunier L

    更新日期:1989-09-01 00:00:00

  • Electronic health record-based predictive models for acute kidney injury screening in pediatric inpatients.

    abstract::BackgroundAcute kidney injury (AKI) is common in pediatric inpatients and is associated with increased morbidity, mortality, and length of stay. Its early identification can reduce severity.MethodsTo create and validate an electronic health record (EHR)-based AKI screening tool, we generated temporally distinct develo...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2017.116

    authors: Wang L,McGregor TL,Jones DP,Bridges BC,Fleming GM,Shirey-Rice J,McLemore MF,Chen L,Weitkamp A,Byrne DW,Van Driest SL

    更新日期:2017-09-01 00:00:00

  • Early-life growth of preterm infants and its impact on neurodevelopment.

    abstract:BACKGROUND:Increasing numbers of preterm-born children survive nowadays, and improving long-term health and neurodevelopment is becoming more important. Early-life growth has been linked to neurodevelopmental outcomes. We aimed to study whether this association has changed with time. METHODS:We studied two cohorts of ...

    journal_title:Pediatric research

    pub_type: 杂志文章,多中心研究

    doi:10.1038/s41390-018-0139-0

    authors: Ruys CA,Hollanders JJ,Bröring T,van Schie PEM,van der Pal SM,van de Lagemaat M,Lafeber HN,Rotteveel J,Finken MJJ

    更新日期:2019-02-01 00:00:00

  • Oral carrageenan induces antigen-dependent oral tolerance: prevention of anaphylaxis and induction of lymphocyte anergy in a murine model of food allergy.

    abstract::Immunosuppressive effects of carrageenan, a high-molecular-weight polysaccharide, on antibody and T cell responses have been previously demonstrated. However, its effect on anaphylaxis is unknown. Our objectives were to test carrageenan-mediated oral tolerance induction in young mice subsequently sensitized to a commo...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-200103000-00018

    authors: Frossard CP,Hauser C,Eigenmann PA

    更新日期:2001-03-01 00:00:00

  • Low incidence of childhood celiac disease in The Netherlands.

    abstract::The incidence and prevalence of celiac disease vary internationally. We studied the incidence of identified cases of childhood celiac disease in six Dutch provinces that cover 47.9% of the surface area and 67.6% of the total population of The Netherlands. Children with celiac disease aged 0-14 y, diagnosed from Januar...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199502000-00015

    authors: George EK,Mearin ML,van der Velde EA,Houwen RH,Bouquet J,Gijsbers CF,Vandenbroucke JP

    更新日期:1995-02-01 00:00:00

  • Immunoprophylaxis and immunotherapy of respiratory syncytial virus-infected mice with respiratory syncytial virus-specific immune serum.

    abstract::The effects of passive respiratory syncytial virus (RSV) immune serum given as preinoculation prophylaxis, postinoculation prophylaxis, and as therapy on d 5 after inoculation were evaluated in an illness model of RSV infection in BALB/c mice. Pre- and postinoculation prophylaxis reduced RSV replication in lung after ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199308000-00013

    authors: Graham BS,Davis TH,Tang YW,Gruber WC

    更新日期:1993-08-01 00:00:00

  • Immediate hypothermia reduces cardiac troponin I after hypoxic-ischemic encephalopathy in newborn pigs.

    abstract::Neonatal hypoxic-ischemic encephalopathy (HIE) is a clinically defined neurological condition after lack of oxygen and often associated with cardiac dysfunction in term infants. Therapeutic hypothermia (HT) after birth is neuroprotective in infants with HIE. However, it is not known whether HT is also cardioprotective...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e31822941ee

    authors: Liu X,Tooley J,Løberg EM,Suleiman MS,Thoresen M

    更新日期:2011-10-01 00:00:00

  • Influence of metabolic control on growth in homocystinuria due to cystathionine B-synthase deficiency.

    abstract::The etiology of the tall stature almost invariably seen in homocystinuric patients is not known. The effect of metabolic control and the role of the GH-IGF system on growth were investigated in 10 patients with homocystinuria. There was a direct correlation between the plasma free homocyst(e)ine and growth velocity SD...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-200106000-00014

    authors: Topaloglu AK,Sansaricq C,Snyderman SE

    更新日期:2001-06-01 00:00:00

  • Elevated protein carbonyls and lipid peroxidation products correlating with myeloperoxidase in tracheal aspirates from premature infants.

    abstract::The purpose of this study is to determine whether the oxidative injury markers, protein carbonyls and malondialdehyde (MDA), are elevated in tracheal aspirates from very low birth weight (< 1500 g) infants; to determine whether levels correlate with myeloperoxidase as a marker of neutrophil inflammation; and to assess...

    journal_title:Pediatric research

    pub_type: 临床试验,杂志文章

    doi:10.1203/00006450-200005000-00014

    authors: Buss IH,Darlow BA,Winterbourn CC

    更新日期:2000-05-01 00:00:00

  • Thyroid hormones in human milk and their influence on thyroid function of breast-fed babies.

    abstract::Various assay methods for detection of thyroid hormones in human milk were evaluated in recovery and dilution experiments after which the concentrations of thyroxine (T4) and 3,5,3'-triiodothyronine (T3) were measured and compared with those in serum. The effect of breast feeding on pituitary thyroid function of norma...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198306000-00008

    authors: Mizuta H,Amino N,Ichihara K,Harada T,Nose O,Tanizawa O,Miyai K

    更新日期:1983-06-01 00:00:00

  • Hypoxia-ischemia stimulates hippocampal glutamate efflux in perinatal rat brain: an in vivo microdialysis study.

    abstract::We used in vivo microdialysis to determine the impact of a focal hypoxic-ischemic insult on hippocampal amino acid efflux in the immature brain. Microdialysis probes were inserted into the right hippocampus of postnatal d 7 rats. To induce hypoxic-ischemic injury, the right carotid artery was ligated and animals were ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199112000-00021

    authors: Silverstein FS,Naik B,Simpson J

    更新日期:1991-12-01 00:00:00

  • Increase of tryptophan and 5-hydroxyindole acetic acid in the brain of ornithine carbamoyltransferase deficient sparse-fur mice.

    abstract::Sparse-fur mice, 28 d of age with the x-chromosomal inherited defect of ornithine carbamoyltransferase, were used to investigate if tryptophan and the serotonin pathway in the brain are affected in this animal model which closely resembles the human inborn error of metabolism. Increased concentrations of tryptophan an...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198404000-00014

    authors: Bachmann C,Colombo JP

    更新日期:1984-04-01 00:00:00

  • No neuroprotective effect of erythropoietin under clinical treatment conditions in a rabbit model of Escherichia coli meningitis.

    abstract::Despite effective antibiotic treatment, neuronal injury is frequent among children and adults with bacterial meningitis resulting in a high rate of death and neurologic sequelae. The hematopoietic cytokine erythropoietin (EPO) provides neuroprotection in models of acute and chronic neurologic diseases. We studied whet...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e318159af7a

    authors: Spreer A,Gerber J,Hanssen M,Nau R

    更新日期:2007-12-01 00:00:00

  • Pharmacokinetics and local safety profile of propranolol eye drops in rabbits.

    abstract:BACKGROUND:Oral propranolol, a nonselective β-blocker, is able to reduce the progression of retinopathy of prematurity in newborns, but it appeared unsafe. This study aimed to find, in rabbits, a propranolol eye drop concentration able to induce lower plasma but higher retinal concentrations than those obtained after o...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2014.108

    authors: Padrini L,Isacchi B,Bilia AR,Pini A,Lanzi C,Masini E,Della Bona ML,Calvani AM,Ceccantini R,la Marca G,Filippi L

    更新日期:2014-10-01 00:00:00

  • Longitudinal study of umbilical and portal venous blood flow to the fetal liver: low pregnancy weight gain is associated with preferential supply to the fetal left liver lobe.

    abstract::Recent data suggest that umbilical venous perfusion of the fetal liver has an important influence on fetal growth and postnatal liver function, and that maternal factors in late pregnancy modify this circulation. In a longitudinal study of 160 low-risk pregnancies, we determined how umbilical and portal venous blood f...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/pdr.0b013e318163a1de

    authors: Kessler J,Rasmussen S,Godfrey K,Hanson M,Kiserud T

    更新日期:2008-03-01 00:00:00

  • Oral insulin increases small intestinal mass and disaccharidase activity in the newborn miniature pig.

    abstract::Factors, such as insulin, found in human and pig colostrum and mature milk likely influence small intestinal growth and development. Although pharmacologic doses of insulin injected parenterally may accelerate small intestinal development in altricial animals such as the rodent, the effects of oral insulin on intestin...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199008000-00018

    authors: Shulman RJ

    更新日期:1990-08-01 00:00:00

  • Succinyl-CoA ligase deficiency: a mitochondrial hepatoencephalomyopathy.

    abstract::This patient presented on the first day of life with pronounced lactic acidosis with an elevated lactate/pyruvate ratio. Urine organic acids showed Krebs cycle metabolites and mildly elevated methylmalonate and methylcitrate. The acylcarnitine profile showed elevated propionylcarnitine and succinylcarnitine. Amino aci...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e3181e5c3a4

    authors: Van Hove JL,Saenz MS,Thomas JA,Gallagher RC,Lovell MA,Fenton LZ,Shanske S,Myers SM,Wanders RJ,Ruiter J,Turkenburg M,Waterham HR

    更新日期:2010-08-01 00:00:00

  • Chronic partial ureteral obstruction in the neonatal guinea pig. I. Influence of uninephrectomy on growth and hemodynamics.

    abstract::Although obstructive nephropathy is a frequent cause of renal insufficiency in infancy, factors influencing adaptation to chronic partial ureteral obstruction (CPUO) are poorly understood. Guinea pigs were subjected to unilateral CPUO within the first 2 days of life (Group I) and microsphere studies were performed at ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198412000-00008

    authors: Chevalier RL,Kaiser DL

    更新日期:1984-12-01 00:00:00

  • Cartilage of I-cell disease.

    abstract::Biochemical analysis and morphologic observation of the iliac crest cartilage from 8-year-old girl with I-cell disease were performed. Instead of hypertrophic change of chondrocytes in the zone of cartilage-bone junction, there were small atrophic cells having many inclusion bodies accumulated with lamellar materials....

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-198104000-00008

    authors: Nogami H,Oohira A,Suzuki F,Tsuda K

    更新日期:1981-04-01 00:00:00

  • Basal and pentagastrin-stimulated acid secretion in newborn human infants.

    abstract::Basal and pentagastrin-stimulated gastric acid secretion was measured in 26 healthy newborn infants on the 1st and 2nd days of life. Basal acid outputs (BAO) on day 1 (0.378 mEq/hr) and day 2 (0.388 mEq/hr) were similar and not significantly different from the maximal acid outputs (MAO) on day 1 (0.413 mEq/hr) and day...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-197901000-00008

    authors: Euler AR,Byrne WJ,Meis PJ,Leake RD,Ament ME

    更新日期:1979-01-01 00:00:00

  • Feasibility of long-term continuous EEG monitoring during the first days of life in preterm infants: an automated quantification of the EEG activity.

    abstract::Long-term EEG monitoring (LTM) with several electrodes could be a useful tool for surveillance of the brain during the first critical days of life. This study aimed to assess the feasibility of multichannel LTM for automated analysis of EEG activity from d 1 to 3 using eight electrodes. Premature infants (GA <31 wk; n...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/PDR.0b013e31821267d2

    authors: Schumacher EM,Westvik AS,Larsson PG,Lindemann R,Westvik J,Stiris TA

    更新日期:2011-05-01 00:00:00

  • Metabolomic and proteomic analysis of serum from preterm infants with necrotising entercolitis and late-onset sepsis.

    abstract:BACKGROUND:Necrotising enterocolitis (NEC) and late-onset sepsis (LOS) are the leading causes of death among preterm infants in the developed world. This study aimed to explore the serum proteome and metabolome longitudinally in preterm infants with NEC or LOS, matched to controls. METHODS:Nineteen patients (10 cases,...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1038/pr.2015.235

    authors: Stewart CJ,Nelson A,Treumann A,Skeath T,Cummings SP,Embleton ND,Berrington JE

    更新日期:2016-03-01 00:00:00

  • Interleukin-8/CXCL8 forms an autocrine loop in fetal intestinal mucosa.

    abstract::IL-8/CXC ligand (CXCL) 8 is ingested in high concentrations by the human fetus/neonate with amniotic fluid and human milk, and is also produced constitutively by intestinal epithelial cells (IEC). We have shown that recombinant human IL-8/CXCL8 (rhIL-8/CXCL8) protects cultured IEC against tumor necrosis factor (TNF)-a...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/01.PDR.0000133196.25949.98

    authors: Maheshwari A,Lacson A,Lu W,Fox SE,Barleycorn AA,Christensen RD,Calhoun DA

    更新日期:2004-08-01 00:00:00

  • Biochemical manifestations of oxygen toxicity in the newborn lamb.

    abstract::The purpose of this project was to study the role of lipid peroxidation in oxygen-induced lung injury in the newborn lamb. It was our hypothesis that injury to the microvascular bed of the lung by oxygen would coincide with a burst of peroxidative activity and would be accompanied by an increased rate of excretion of ...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/00006450-199012000-00014

    authors: Hansen TN,Smith CV,Gest AL,Smith HW,Giesler M

    更新日期:1990-12-01 00:00:00

  • Effect of television viewing at mealtime on food intake after a glucose preload in boys.

    abstract::Television viewing (TVV) is considered a contributing factor to the development of childhood obesity yet it is unclear whether obesity results, in part, from increased energy intake during TVV. The objective of this study was to determine the effect of TVV on food intake (FI) of boys at a meal and its effect on calori...

    journal_title:Pediatric research

    pub_type: 杂志文章

    doi:10.1203/pdr.0b013e3180536591

    authors: Bellissimo N,Pencharz PB,Thomas SG,Anderson GH

    更新日期:2007-06-01 00:00:00