Differential effects of glucocorticoids and mineralocorticoids on the mRNA expression of colon ion transporters in infant rats.

abstract：:Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) commonly affects premature neonates. The gravity of the consequences associated with GMH-IVH makes it a major concern in their care. GMH-IVH begins in the germinal matrix tissue and is, most commonly, the result of venous rupture. Arteriole-to-venous pre...

journal_title：Pediatric research

authors： Anstrom JA,Brown WR,Moody DM,Thore CR,Challa VR,Block SM

更新日期：2002-10-01 00:00:00

abstract：:Basal and pentagastrin-stimulated gastric acid secretion was measured in 26 healthy newborn infants on the 1st and 2nd days of life. Basal acid outputs (BAO) on day 1 (0.378 mEq/hr) and day 2 (0.388 mEq/hr) were similar and not significantly different from the maximal acid outputs (MAO) on day 1 (0.413 mEq/hr) and day...

journal_title：Pediatric research

authors： Euler AR,Byrne WJ,Meis PJ,Leake RD,Ament ME

更新日期：1979-01-01 00:00:00

abstract：:Early-life stress has been shown to destabilize the homeostatic synaptic plasticity and compromise the developing brain to the later encountered insults. This study would determine the long-term epileptogenic effect of neonatal isolation (NI) on early-life seizure. There were five groups: normal rearing (NR) rats; NI ...

journal_title：Pediatric research

authors： Lai MC,Lui CC,Yang SN,Wang JY,Huang LT

更新日期：2009-10-01 00:00:00

abstract：:In an effort to characterize the hepatic abnormality in patients with alpha1-antitrypsin deficiency, three unrelated children with the disorder (Pi types ZZ and SZ), two heterozygous parents (Pi type MZ), and three normal subjects (Pi type MM) were studied. As expected, the livers of the ZZ- and SZ-deficient subjects ...

journal_title：Pediatric research

authors： Bhan AK,Grand RJ,Colten HR,Alper CA

更新日期：1976-01-01 00:00:00

abstract：:BackgroundTo examine the mechanism of urethral seam formation during embryonal development of rat urethra.MethodsTime-mated Sprague-Dawley rats were killed and the genital tubercles of male pups harvested on embryonic day (ED) 15, 16, 18, and 19. External morphology was observed under scanning electron microscope. Ser...

journal_title：Pediatric research

authors： Zhou Y,Liu X,Huang F,Liu Y,Cao X,Shen L,Long C,He D,Lin T,Wei G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of the study was to describe and contrast the brain development and outcome among very preterm infants that were and were not exposed to surgery requiring general anesthesia prior to term equivalent age (TEA). METHODS:Preterm infants born ≤30 weeks' gestation who did (n = 25) and did not (n = 59) ha...

journal_title：Pediatric research

authors： Walsh BH,Paul RA,Inder TE,Shimony JS,Smyser CD,Rogers CE

更新日期：2020-06-23 00:00:00

abstract：:Infants with sudden infant death syndrome have higher hypoxanthine (Hx) concentrations in their vitreous humor than infants with respiratory distress syndrome and other infant control populations. However, previous research on piglets and pigs applying continuous hypoxemia has not been able to reproduce the concentrat...

journal_title：Pediatric research

authors： Stoltenberg L,Rootwelt T,Oyasaeter S,Rognum TO,Saugstad OD

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Intranasal corticosteroids are the most efficacious anti-inflammatory medications for allergic rhinitis (AR). However, the efficacy and safety of intranasal corticosteroids in children have not yet been subject to specific research in China. The aim of this study was to investigate the efficacy and safety of...

journal_title：Pediatric research

authors： Zhang Y,Wei P,Chen B,Li X,Luo X,Chen X,Xiang M,Li L,Zhao S,Xiao X,Yang X,Chen J,Fu Y,Xiao S,Liu H,Cheng L,Yao H

更新日期：2020-10-02 00:00:00

abstract：:The change in the pattern of biotransformation of [14C]corticosterone in fetal mouse brain between gestational day 14 and 17 increased the proportion of unchanged hormone from 9-75%. A sharp decrease in the in vitro incorporation of [14C]leucine, [3H]uridine, and [3H]thymidine into incubated brain coincided with this ...

journal_title：Pediatric research

authors： Tye LM,Michaud NJ,Burton AF

更新日期：1978-12-01 00:00:00

abstract：:Defective arousal mechanisms are viewed as contributory to sleep hypopnea disorders and sudden infant death syndrome. Sighs (i.e. augmented breaths) as well as startles have not traditionally been viewed as arousal-related phenomena in infants. We hypothesized that, if sighs and startles are the initial event in a seq...

journal_title：Pediatric research

authors： Wulbrand H,McNamara F,Thach BT

更新日期：1998-11-01 00:00:00

abstract：:We banded the trachea of 4-wk-old male rats and studied lung growth, lung morphometry, and static pulmonary mechanics 4 wk later. We compared the experimental animals to sham-operated male littermates of the same age, 8-wk-old normal male littermates, and weight-matched rats of a younger age. Tracheal banded animals w...

journal_title：Pediatric research

authors： Kida K,Thurlbeck WM

更新日期：1981-03-01 00:00:00

abstract：:A patient is reported who presented in the newborn period with an unusual combination of congenital lactic acidosis and bilateral calcifications in the adrenal medulla, visible on standard abdominal x-ray and ultrasound examination. At birth, the proband was hypotonic and dystrophic. She developed respiratory insuffic...

journal_title：Pediatric research

authors： Zecic A,Smet JE,De Praeter CM,Vanhaesebrouck P,Viscomi C,Van Den Broecke C,De Paepe B,Lohse P,Martin JJ,Jackson JG,Campbell CR,De Meirleir LJ,Zeviani M,Seneca SH,Lissens W,Van Coster RN

更新日期：2009-09-01 00:00:00

abstract：:Critically ill infants are treated with dexamethasone (Dx) and other glucocorticoids to reduce inflammation and to promote lung and cardiac function. The neonatal immune system is immature, so neonatal dendritic cells (DCs) might be especially sensitive to glucocorticoid-mediated immunosuppression. To test this, we co...

journal_title：Pediatric research

authors： Mainali ES,Kikuchi T,Tew JG

更新日期：2005-07-01 00:00:00

abstract：:BackgroundPatent ductus arteriosus (PDA) is a common complication seen in preterm infants. Indomethacin is routinely used to treat PDA. Evidence suggests that the response of indomethacin is highly heritable. This study investigated the association between single-nucleotide polymorphisms (SNPs) in CYP2C9 and the closu...

journal_title：Pediatric research

authors： Smith CJ,Ryckman KK,Bahr TM,Dagle JM

更新日期：2017-11-01 00:00:00

abstract：:Studies were conducted to assess the efficacy and safety of a synthetic peptide-containing surfactant in the treatment of respiratory distress syndrome (RDS) in preterm (approximately 80% of normal gestation) infant rhesus monkeys. Surfactant was prepared consisting of the phospholipids dipalmitoylphosphatidyl choline...

journal_title：Pediatric research

authors： Revak SD,Merritt TA,Cochrane CG,Heldt GP,Alberts MS,Anderson DW,Kheiter A

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:In Celiac disease (CD), cytoskeletal integrity of intestinal cells is disrupted by gliadin exposure. This study investigates the role of heat shock protein (Hsp)70 during cytoskeletal recovery in CD by assessing its induction and effects on junctional proteins. METHODS:Using an in-vitro model of CD, cytoske...

journal_title：Pediatric research

authors： Bidmon-Fliegenschnee B,Lederhuber HCh,Csaicsich D,Pichler J,Herzog R,Memaran-Dadgar N,Huber WD,Aufricht C,Kratochwill K

更新日期：2015-10-01 00:00:00

abstract：:We investigated the role of circulating bone marrow cells (BMC) in cardiomyocyte regeneration. BMC, isolated from transgenic mice expressing enhanced green fluorescent protein (GFP), were transplanted into lethally irradiated C57BL6 mice. Five weeks after bone marrow transplantation (BMT), flow cytometric analysis for...

journal_title：Pediatric research

authors： Kuramochi Y,Fukazawa R,Migita M,Hayakawa J,Hayashida M,Uchikoba Y,Fukumi D,Shimada T,Ogawa S

更新日期：2003-09-01 00:00:00

abstract：:Although tyrosine is considered indispensable during the neonatal period, its poor solubility has limited its inclusion in parenteral amino acid solutions to less than 1% of total amino acids. Dipeptides of tyrosine are highly soluble, have been shown to be well used and safe in animal models and humans, and, therefor...

journal_title：Pediatric research

authors： Roberts SA,Ball RO,Moore AM,Filler RM,Pencharz PB

更新日期：2001-01-01 00:00:00

abstract：:In neuronal cultures from the forebrain of 14-d-old rat embryos, transient hypoxia (95% N2/5% CO2, 37 degrees C) for 6 h has been shown to trigger delayed apoptotic death through sequential changes in protein synthesis, whereas preconditioning by a brief episode of hypoxia can rescue neurons. Because hypothermia has b...

journal_title：Pediatric research

authors： Bossenmeyer-Pourié C,Koziel V,Daval JL

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Following our clinical observation of tonic responses in response to the knee jerk in infants at very high risk for cerebral palsy (VHR infants), we systematically studied tonic responses, clonus, and reflex irradiation. We questioned (i) whether these responses occurred more often in VHR infants than in typ...

journal_title：Pediatric research

authors： Hamer EG,Dijkstra LJ,Hooijsma SJ,Zijdewind I,Hadders-Algra M

更新日期：2016-09-01 00:00:00

abstract：:Fetal growth restriction (FGR) remains a cause of perinatal brain injury, sometimes leading to neurological and intellectual impairment. Although the mechanisms and pathophysiology of CNS injuries have not been elucidated completely, it is possible carbohydrate and energy metabolism may have an important role in the F...

journal_title：Pediatric research

authors： Hayakawa M,Sato Y,Hattori T,Ichinohashi Y,Nakayama A,Yamamoto H,Hemmi H,Ito M,Ieda K,Kojima S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Macrosomia and child obesity are growing health-care issues worldwide. The purpose of the study was to evaluate how extremely high or low birth weight affects metabolic markers evaluated in newborn screening. METHODS:The study was register-based and included full-term singletons born in Iceland from 2009 to...

journal_title：Pediatric research

authors： Vidarsdottir H,Thorkelsson T,Halldorsson TI,Bjarnason R,Geirsson RT,Rinaldo P,Franzson L

更新日期：2020-06-29 00:00:00

abstract：:Intestinal absorption and its relationship to increased total body water was studied in seven infants with congenital heart disease receiving regular diuretics due to congestive heart failure. All infants and six age-matched healthy controls were studied for a 3-d period during which time all food intake was recorded,...

journal_title：Pediatric research

authors： Vaisman N,Leigh T,Voet H,Westerterp K,Abraham M,Duchan R

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Histomorphometry of endomyocardial biopsies is one component of arrhythmogenic right ventricular cardiomyopathy (ARVC) diagnosis, although there is a need for stricter diagnostic criteria for this disease in pediatrics. The clinical utility of biopsy analysis as a component of ARVC diagnosis was evaluated in...

journal_title：Pediatric research

authors： Sreetharan S,MacIntyre CJ,Fatah M,Warren AE,Wilson GJ,Hamilton RM

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Previous studies indicate an increased risk for neuropsychological difficulties in young children prenatally exposed to opioids and polysubstances, but longitudinal information is scarce. The present longitudinal study investigated whether these waned, persisted, or increased over time. METHODS:The cognitiv...

journal_title：Pediatric research

authors： Nygaard E,Moe V,Slinning K,Walhovd KB

更新日期：2015-09-01 00:00:00

abstract：:Several neuropathologic findings in infants and children with human immunodeficiency virus type-1 (HIV-1) infection are different from those observed in adults, probably related to the fact that the retroviral infection occurs in the setting of neuro-development. This report describes the interaction and biologic acti...

journal_title：Pediatric research

authors： Cornaglia-Ferraris P,De Maria A,Cirillo C,Cara A,Alessandri G

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:To investigate relationships between infant body composition (BC) and human milk (HM) immunomodulatory proteins (IMPs) during the first 12 months of lactation. METHODS:BC of breastfeeding dyads (n = 20) was measured with ultrasound skinfolds (infants) and bioimpedance spectroscopy (infants/mothers) at 2, 5,...

journal_title：Pediatric research

authors： Gridneva Z,Lai CT,Rea A,Tie WJ,Ward LC,Murray K,Hartmann PE,Geddes DT

更新日期：2020-05-21 00:00:00

abstract：:Lung infections are a common cause of morbidity and mortality in neonates. To evaluate neonatal lung defenses against pneumococci, we challenged rats with aerosols of encapsulated pneumococci in an airborne infection apparatus. Whereas adult rats cleared greater than 95% of inhaled type 1 or type 25 pneumococci within...

journal_title：Pediatric research

authors： Coonrod JD,Jarrells MC,Bridges RB

更新日期：1987-12-01 00:00:00

abstract：:The effect of diet, human milk or formula, on gastric function (lipase and pepsin activity, pH, and volume) and intragastric digestion of fat was assessed in 28 appropriate for gestational age preterm infants (gestational age, 28.9 +/- 1.4, 29.1 +/- 0.9, 29.5 +/- 0.6 wk; birth weight, 1.00 +/- 0.14 to 1.18 +/- 0.07 kg...

journal_title：Pediatric research

authors： Armand M,Hamosh M,Mehta NR,Angelus PA,Philpott JR,Henderson TR,Dwyer NK,Lairon D,Hamosh P

更新日期：1996-09-01 00:00:00

abstract：:The neuroprotective effect of hypothermia instituted after resuscitation from asphyxic cardiac arrest has not been studied in immature brain, particularly in a large animal model with recovery periods greater than 4 d. Moreover, protection from severe hypoxia seen with 3 h of hypothermia was reported to be lost when h...

journal_title：Pediatric research

authors： Agnew DM,Koehler RC,Guerguerian AM,Shaffner DH,Traystman RJ,Martin LJ,Ichord RN

更新日期：2003-08-01 00:00:00