Impact of anatomical and functional severity of coronary atherosclerotic plaques on the transmural perfusion gradient: a [15O]H2O PET study.

abstract：AIMS:Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients. E...

journal_title：European heart journal

authors： Hoetzenecker K,Zimmermann M,Hoetzenecker W,Schweiger T,Kollmann D,Mildner M,Hegedus B,Mitterbauer A,Hacker S,Birner P,Gabriel C,Gyöngyösi M,Blyszczuk P,Eriksson U,Ankersmit HJ

更新日期：2015-03-14 00:00:00

abstract：AIMS:Recent randomized trials suggest that intensive glycaemic control fails to reduce heart failure-related events in patients with diabetes. The molecular cues underlying persistent myocardial damage despite normoglycaemia restoration remain elusive. MicroRNAs (miRNAs), a class of small non-coding RNAs, orchestrate t...

journal_title：European heart journal

authors： Costantino S,Paneni F,Lüscher TF,Cosentino F

更新日期：2016-02-07 00:00:00

abstract：:A 54 year old woman with isolated stenosis of the left coronary ostium died following cardiac catheterisation and emergency coronary artery bypass surgery. Histological examination showed the ostial narrowing to be a local and discrete plaque of atherosclerosis. Like most reported cases this patient was a young woman ...

journal_title：European heart journal

authors： Stewart JT,Ward DE,Davies MJ,Pepper JR

更新日期：1987-08-01 00:00:00

abstract：AIMS:It is reported that one third of patients with heart failure have normal left ventricular systolic function, and may or may not have left ventricular diastolic dysfunction. We sought to define the prevalence of left ventricular diastolic filling abnormalities in a large unselected group of patients, unlike the dia...

journal_title：European heart journal

authors： Davie AP,Francis CM,Caruana L,Sutherland GR,McMurray JJ

更新日期：1997-06-01 00:00:00

abstract：:Intracoronary blood flow velocity measurements with a Doppler balloon catheter and the radiographic assessment of myocardial perfusion with contrast media, before and after the intracoronary administration of papaverine, have previously been used to investigate regional coronary flow reserve. In the present study we a...

journal_title：European heart journal

authors： Serruys PW,Zijlstra F,Laarman GJ,Reiber HH,Beatt K,Roelandt J

更新日期：1989-08-01 00:00:00

abstract：AIMS:The purpose of this study was to identify novel genetic variants influencing circulating asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) levels and to evaluate whether they have a prognostic value on cardiovascular mortality. METHODS AND RESULTS:We conducted a genome-wide association stud...

journal_title：European heart journal

authors： Seppälä I,Kleber ME,Lyytikäinen LP,Hernesniemi JA,Mäkelä KM,Oksala N,Laaksonen R,Pilz S,Tomaschitz A,Silbernagel G,Boehm BO,Grammer TB,Koskinen T,Juonala M,Hutri-Kähönen N,Alfthan G,Viikari JS,Kähonen M,Raitakari OT,

更新日期：2014-02-01 00:00:00

abstract：:To assess the clinical significance of monitoring during physical training in post-myocardial infarction (MI) patients with asymptomatic exercise-induced ischaemia, we studied 232 patients who were survivors of first recent acute MI and consecutively admitted to the same CCU, who underwent an exercise test (ET) and co...

journal_title：European heart journal

authors： Opasich C,Riccardi G,Assandri J,Calsamiglia G,Forni R,La Rovere M,Cobelli F,De Servi S,Specchia G

更新日期：1988-12-01 00:00:00

abstract：:The effects of oral sotalol were compared with the findings obtained in the baseline study of a group of 26 consecutive patients with sustained monomorphic ventricular tachycardia or ventricular fibrillation and inducible ventricular tachycardia. The mean age was 62 years and the mean ejection fraction 33%. The number...

journal_title：European heart journal

authors： Jordaens LJ,Palmer A,Clement DL

更新日期：1989-03-01 00:00:00

abstract：AIM:To investigate fatalities from myocardial infarction at 28 days and one-year among patients aged 35-64 years in the Nordic and Lithuanian centres participating in the World Health Organization MONICA (Monitoring of Trends and Determinants of Cardiovascular Disease) Project. METHODS AND RESULTS:Altogether 9100 myoc...

journal_title：European heart journal

authors： Salomaa VV,Lundberg V,Agnarsson U,Radisauskas R,Kirchhoff M,Wilhelmsen L

更新日期：1997-01-01 00:00:00

abstract：:Modern-day stenting procedures leverage advances in pharmacotherapy and device innovation. Patients treated with contemporary antiplatelet agents, peri-procedural antithrombin therapy and new-generation drug-eluting stents (DES) have excellent outcomes over the short to medium term. Indeed, coupled with the reducing c...

journal_title：European heart journal

authors： Byrne RA,Joner M,Kastrati A

更新日期：2015-12-14 00:00:00

abstract：:A 55-year-old woman presented with fever and malaise. Three blood cultures were positive for Streptococcus sanguis. A diagnosis of endocarditis was made and the patient was treated with intravenous penicillin and gentamicin. Endocardiography revealed a large left atrial tumour. At operation a myxoma covered by deposit...

journal_title：European heart journal

authors： ten Berg JM,Elbers HR,Defauw JJ,Plokker HW

更新日期：1992-11-01 00:00:00

abstract：AIMS:Cardioprotective effects of erythropoietin (EPO) have been shown in experimental and smaller clinical studies. We performed a prospective, multicentre, randomized trial to assess the effects of a single high dose of EPO after primary coronary intervention (PCI) for an ST-elevation myocardial infarction (STEMI). Me...

journal_title：European heart journal

authors： Voors AA,Belonje AM,Zijlstra F,Hillege HL,Anker SD,Slart RH,Tio RA,van 't Hof A,Jukema JW,Peels HO,Henriques JP,Ten Berg JM,Vos J,van Gilst WH,van Veldhuisen DJ,HEBE III Investigators.

更新日期：2010-11-01 00:00:00

abstract：:Large-scale trials have demonstrated a consistent mortality reduction from angiotensin converting enzyme (ACE) inhibitor therapy for chronic heart failure. Nonetheless, the pharmacologic and physiologic mechanisms of this favourable affect and the appropriate target population remain controversial. ACE inhibitors exer...

journal_title：European heart journal

authors： Cohn JN

更新日期：1995-12-01 00:00:00

abstract：AIMS:This prospective, randomized, controlled, multicentre study aimed to evaluate efficacy and safety of exercise training in patients with pulmonary arterial (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). METHODS AND RESULTS:For the first time a specialized PAH/CTEPH rehabilitation programme was im...

journal_title：European heart journal

authors： Grünig E,MacKenzie A,Peacock AJ,Eichstaedt CA,Benjamin N,Nechwatal R,Ulrich S,Saxer S,Bussotti M,Sommaruga M,Ghio S,Gumbiene L,Palevičiūtė E,Jurevičienė E,Cittadini A,Stanziola AA,Marra AM,Kovacs G,Olschewski H,Barb

更新日期：2020-11-24 00:00:00

abstract：AIMS:Diastolic dysfunction in acute myocardial infarction (MI) is associated with adverse outcome. Recently, the ratio of early mitral inflow velocity (E) to global diastolic strain rate (e'sr) has been proposed as a marker of elevated LV filling pressure. However, the prognostic value of this measure has not been demo...

journal_title：European heart journal

authors： Ersbøll M,Andersen MJ,Valeur N,Mogensen UM,Fakhri Y,Thune JJ,Møller JE,Hassager C,Søgaard P,Køber L

更新日期：2014-03-01 00:00:00

abstract：:Cardiac output was measured in 11 patients undergoing routine cardiac catheterization using a carbon dioxide rebreathing technique and compared with cardiac output measured by direct Fick and thermodilution. The carbon dioxide rebreathing technique gave consistently lower values for cardiac output than the other two m...

journal_title：European heart journal

authors： Nugent AM,McParland J,McEneaney DJ,Steele I,Campbell NP,Stanford CF,Nicholls DP

更新日期：1994-03-01 00:00:00

abstract：:Congestive heart failure is the most common cause of death in young adults with thalassaemia major. In the present study we compared atrial natriuretic peptide levels (ANP) in 30 asymptomatic patients with thalassaemia major (aged 16.6 +/- 6.4 years), normal left ventricular diastolic cavity dimension and systolic fun...

journal_title：European heart journal

authors： Derchi G,Bellone P,Forni GL,Lupi G,Jappelli S,Randazzo M,Zino V,Vecchio C

更新日期：1992-10-01 00:00:00

abstract：:Myocardial catecholamine concentrations were determined in endomyocardial biopsies from patients with heart failure to assess if tissue catecholamine levels relate to the severity of myocardial damage or the aetiology of the underlying disease. Methodological studies revealed a good reproducibility of catecholamine de...

journal_title：European heart journal

authors： Regitz V,Leuchs B,Bossaller C,Sehested J,Rappolder M,Fleck E

更新日期：1991-08-01 00:00:00

abstract：AIMS:Carotid intima-media thickness (CIMT) and plaque information can improve coronary heart disease (CHD) risk prediction when added to traditional risk factors (TRF). However, obtaining adequate images of all carotid artery segments (A-CIMT) may be difficult. Of A-CIMT, the common carotid artery intima-media thicknes...

journal_title：European heart journal

authors： Nambi V,Chambless L,He M,Folsom AR,Mosley T,Boerwinkle E,Ballantyne CM

更新日期：2012-01-01 00:00:00

abstract：:In 103 hearts with various forms of cardiac muscle hypertrophy the following parameters were estimated: diameter, length, volume, density and number of myocytes, and density of myocyte nuclei. The values of all histometric parameters correlated well with left ventricular (LV) weight up to 350 g. In heavier hearts thes...

journal_title：European heart journal

authors： Grajek S,Lesiak M,Pyda M,Zajac M,Paradowski S,Kaczmarek E

更新日期：1993-01-01 00:00:00

abstract：AIMS:To document the impact of intensive insulin therapy during intensive care on long-term (4 years) outcome of high-risk cardiac surgery patients. METHODS AND RESULTS:In this pre-planned sub-analysis and follow-up study of a large, randomized controlled trial on the effects of intensive insulin therapy during critic...

journal_title：European heart journal

authors： Ingels C,Debaveye Y,Milants I,Buelens E,Peeraer A,Devriendt Y,Vanhoutte T,Van Damme A,Schetz M,Wouters PJ,Van den Berghe G

更新日期：2006-11-01 00:00:00

abstract：AIMS:We investigated the potential influence of a moderate-to-high cardiovascular (CV) risk (CVR) (defined as a Systematic COronary Risk Evaluation model, or SCORE ≥ 4%), in the absence of an established CV disease, on the duration and cost of CV and non-CV sick leave (SL) resulting from common and occupational acciden...

journal_title：European heart journal

authors： Calvo-Bonacho E,Ruilope LM,Sánchez-Chaparro MA,Cerezo C,Catalina-Romero C,Martínez-Muñoz P,Banegas JR,Waeber B,Gonzalez-Quintela A,Zanchetti A

更新日期：2014-02-01 00:00:00

abstract：:The effects of fentanyl at a dose of 100 micrograms.kg-1 on cardiac automaticity, refractoriness and conduction have been studied in a model of heterotopic heart transplantation which combines a denervated heart (donor) and a non-denervated heart (recipient) in each of 20 dogs employed. Once the surgical procedure had...

journal_title：European heart journal

authors： Alvarez L,Escudero C,Carmona JA,Silva L,Castillo-Olivares JL

更新日期：1992-09-01 00:00:00

abstract：AIMS:To analyse the relationship between initial exercise parameters and peak oxygen consumption and prognosis in 96 patients with congestive heart failure. METHODS AND RESULTS:Comparison of responses during the initial 6 min of cardiopulmonary exercise testing (Naughton modified protocol) in patients stratified to th...

journal_title：European heart journal

authors： de Vries RJ,van Veldhuisen DJ,Dunselman PH,van der Veer N,Crijns HJ

更新日期：1997-12-01 00:00:00

abstract：AIMS:The long QT syndrome is mainly defined by QT interval prolongation (QTc > 0.44s). However, data obtained in genotyped patients showed that resting QTc measurement alone may be inaccurate for ascertaining the phenotype. The aim of this study was to evaluate the diagnostic performance of QT interval rate-dependence ...

journal_title：European heart journal

authors： Neyroud N,Maison-Blanche P,Denjoy I,Chevret S,Donger C,Dausse E,Fayn J,Badilini F,Menhabi N,Schwartz K,Guicheney P,Coumel P

更新日期：1998-01-01 00:00:00

abstract：:A series of 42 patients with chest pain but normal coronary angiograms and normal haemodynamics at rest were prospectively classified as typical angina (group 1, N = 9) or atypical angina (group 2, N = 16) or non-anginal chest pain (group 3, N = 17). All patients underwent radionuclide ventriculography and measurement...

journal_title：European heart journal

authors： Wieshammer S,Delagardelle C,Sigel HA,Henze E,Kress P,Bitter F,Adam WE,Stauch M

更新日期：1986-08-01 00:00:00

abstract：:The utility of high-frequency current applied through the distal electrode of a conventional electrode-catheter for altering atrio-ventricular conduction was studied in 18 anaesthetized dogs. Following adequate unipolar His bundle recording, current was applied over periods of 20-30 s, with an output power of 30 W. Co...

journal_title：European heart journal

authors： Lopez-Merino V,Chorro FJ,Sanchis J,Garcia-Civera R,Such L,Camañas A,Paya R

更新日期：1989-02-01 00:00:00

abstract：AIMS:Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key regulator of extracellular matrix degradation. We examined relations of plasma total TIMP-1 to cardiovascular risk factors and echocardiographic left ventricular (LV) structure and function in a community-based sample. METHODS AND RESULTS:We studied 1069 ...

journal_title：European heart journal

authors： Sundström J,Evans JC,Benjamin EJ,Levy D,Larson MG,Sawyer DB,Siwik DA,Colucci WS,Wilson PW,Vasan RS

更新日期：2004-09-01 00:00:00

abstract：:Thiazide diuretics are efficacious, either as monotherapy or in combination with other antihypertensive drugs. They reduce blood pressure in a high percentage of hypertensive patients with minimal subjective side effects. There is increasing evidence that the use of diuretics, singly or in combination, will reduce mor...

journal_title：European heart journal

authors： Moser M

更新日期：1992-12-01 00:00:00

abstract：:To investigate the antianginal efficacy and tolerability of felodipine, a new dihydropyridine calcium antagonist, 20 patients with stable exertional angina, not completely controlled by beta-blocker monotherapy, entered a randomized, double-blind, placebo-controlled, crossover study. Patients on standard beta-blocker ...

journal_title：European heart journal

authors： Sangiorgio P,Di Pasquale G,Savonitto S,Urbinati S,Rubboli A,Cavallotti G,Pinelli G,Bracchetti D

更新日期：1990-11-01 00:00:00