Complications of the flow-directed pulmonary artery catheter: A prospective analysis in 219 patients.


:In order to determine and analyze the complication rate of the insertion and maintenance of the balloon-tipped, flow-directed pulmonary artery catheter (PAC), the authors prospectively studied the use of 320 catheters in 219 critically ill patients. Mean patient age was 53 +/- 1 years, and 36% had a history of cardiovascular disease. Mean duration of catheterization averaged 76 +/- 3 h. Major complications occurred in 3% of catheterizations. These included six pneumothoraces; three arrhythmias requiring treatment, one of which was fatal; and one subclavian vein thrombosis. Site complications occurred more frequently in catheters maintained longer than 72 h. These findings suggest that, when indicated in the care of critically ill patients, the properly placed and maintained PAC has an acceptably low morbidity and mortality rate, particularly when used for 72 h or less.


Crit Care Med


Critical care medicine


Sise MJ,Hollingsworth P,Brimm JE,Peters RM,Virgilio RW,Shackford SR




Has Abstract


1981-04-01 00:00:00












  • Early goal-directed sedation versus standard sedation in mechanically ventilated critically ill patients: a pilot study*.

    abstract:OBJECTIVE:To assess the feasibility and safety of delivering early goal-directed sedation compared with standard sedation. DESIGN:Pilot prospective, multicenter, randomized, controlled trial. SETTING:Six ICUs. PATIENTS:Critically ill adults mechanically ventilated for greater than 24 hours. INTERVENTIONS:Patients r...

    journal_title:Critical care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Shehabi Y,Bellomo R,Reade MC,Bailey M,Bass F,Howe B,McArthur C,Murray L,Seppelt IM,Webb S,Weisbrodt L,Sedation Practice in Intensive Care Evaluation Study Investigators.,Australian and New Zealand Intensive Care Society Clinical

    更新日期:2013-08-01 00:00:00

  • Use of glucose-insulin-potassium (GIK) in human septic shock.

    abstract::Fifteen patients with septic shock and perfusion failure received a 20-min infusion of glucose-insulin-potassium (GIK, glucose 50%, 1 g/kg body weight; insulin 1.5 U/kg, potassium, 10 mMol) after volume loading and vasoactive medication had failed to eliminate hypotension and lactacidemia. Hemodynamic and oxygen measu...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Bronsveld W,van den Bos GC,Thijs LG

    更新日期:1985-07-01 00:00:00

  • Positive-pressure ventilation with positive end-expiratory pressure and atrial natriuretic peptide release.

    abstract::The effect of positive-pressure ventilation (PPV) with PEEP on the release of alpha-atrial natriuretic peptide (ANP) was investigated in both humans and an experimental model. In the human study, systemic artery blood samples from 22 critically ill patients were analyzed for ANP. Seventeen of these patients received P...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Teba L,Dedhia HV,Schiebel FG,Blehschmidt NG,Lindner WJ

    更新日期:1990-08-01 00:00:00

  • The unassisted respiratory rate/tidal volume ratio accurately predicts weaning outcome in postoperative patients.

    abstract:OBJECTIVE:To evaluate the accuracies of the respiratory rate/tidal volume ratio (rate/volume ratio), minute volume, and negative inspired force in predicting weaning outcome in postoperative mechanically ventilated patients. DESIGN:A prospective, observational study. SETTING:Surgical intensive care unit of a 270-bed ...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Jacob B,Chatila W,Manthous CA

    更新日期:1997-02-01 00:00:00

  • An evaluation of incentive spirometry in the management of pulmonary complications after cardiac surgery in a pediatric population.

    abstract::Changes in pulmonary function and the development of atelectasis in the postoperative period have been well documented in the adult population. The use of incentive spirometry has been shown to be effective in the prevention of these postoperative complications. At the Hospital of Sick Children, we studied 17 children...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Krastins I,Corey ML,McLeod A,Edmonds J,Levison H,Moes F

    更新日期:1982-08-01 00:00:00

  • Asphyxia by Drowning Induces Massive Bleeding Due To Hyperfibrinolytic Disseminated Intravascular Coagulation.

    abstract:OBJECTIVE:To date, no study has systematically investigated the impact of drowning-induced asphyxia on hemostasis. Our objective was to test the hypothesis that asphyxia induces bleeding by hyperfibrinolytic disseminated intravascular coagulation. DESIGN:Observational study. SETTING:A 2,100-bed tertiary care facility...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Schwameis M,Schober A,Schörgenhofer C,Sperr WR,Schöchl H,Janata-Schwatczek K,Kürkciyan EI,Sterz F,Jilma B

    更新日期:2015-11-01 00:00:00

  • Effect of increased radiant warmer power output on state of hydration in the critically ill neonate.

    abstract::To correlate radiant warmer bed power output with state of hydration in the critically ill infant, warmer power input was measured by a wattmeter and recorded by an on-line computer every 5 sec for 2 periods of 8-24 h each in 11 newborns with respiratory distress syndrome (mean birth weight 1.42 kg, mean gestational a...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Engle WD,Baumgart S,Fox WW,Polin RA

    更新日期:1982-10-01 00:00:00

  • Sepsis and its complications: the clinical problem.

    abstract:OBJECTIVES:To review the difficulties associated with defining sepsis and its complications and to characterize the role of the proinflammatory cytokines in the development of human septic shock, adult respiratory distress syndrome, and the systemic inflammatory response syndrome. DATA SOURCES:Information presented at...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审


    authors: Bone RC

    更新日期:1994-07-01 00:00:00

  • Meconium and amniotic fluid embolism: effects on coagulation in pregnant mini-pigs.

    abstract:OBJECTIVE:A hallmark of amniotic fluid embolism is the induction of coagulation defects. Little is known about the nature of these defects or the causative agent or agents. The purpose of this study was to assess the effects of meconium containing (native) meconium-amniotic-fluid infusion (MAFI) and meconium-free (cent...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Petroianu GA,Altmannsberger SH,Maleck WH,Assmus HP,Friedberg C,Bergler WF,Rüfer R

    更新日期:1999-02-01 00:00:00

  • Randomized Feasibility Trial of a Low Tidal Volume-Airway Pressure Release Ventilation Protocol Compared With Traditional Airway Pressure Release Ventilation and Volume Control Ventilation Protocols.

    abstract:OBJECTIVES:Low tidal volume (= tidal volume ≤ 6 mL/kg, predicted body weight) ventilation using volume control benefits patients with acute respiratory distress syndrome. Airway pressure release ventilation is an alternative to low tidal volume-volume control ventilation, but the release breaths generated are variable ...

    journal_title:Critical care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Hirshberg EL,Lanspa MJ,Peterson J,Carpenter L,Wilson EL,Brown SM,Dean NC,Orme J,Grissom CK

    更新日期:2018-12-01 00:00:00

  • 4-Aminopyridine, A Blocker of Voltage-Dependent K+ Channels, Restores Blood Pressure and Improves Survival in the Wistar Rat Model of Anaphylactic Shock.

    abstract:OBJECTIVES:Anaphylactic shock is associated with severe hypotension. Potassium channel blockers, such as 4-aminopyridine, induce vasoconstriction. The objective of this study was to test the ability of 4-aminopyridine to restore blood pressure and increase survival in anaphylactic shock. DESIGN:Experimental study. SE...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Bellou A,Al-Hammadi S,Aburawi EH,Dhanasekaran S,Nemmar A,Oulhaj A,Shafiuallah M,Zerrouki M,Yasin J,Bellou L,Alper SL,Bellou S,Kazzam E

    更新日期:2016-11-01 00:00:00

  • Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department.

    abstract:OBJECTIVE:First, to determine whether procalcitonin (PCT) significantly adds diagnostic value in terms of sensitivity and specificity to a common set of markers of infection, including C-reactive protein (CRP), at the Emergency Department. Second, to create a simple scoring rule implementing PCT values. Third, to deter...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: de Kruif MD,Limper M,Gerritsen H,Spek CA,Brandjes DP,ten Cate H,Bossuyt PM,Reitsma PH,van Gorp EC

    更新日期:2010-02-01 00:00:00

  • Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine.

    abstract:OBJECTIVE:Our first objective was to determine a blood lactate threshold predictive of survival in human immunodeficiency virus patients experiencing lactic acidosis related to nucleoside analogs, and second, to test l-carnitine for the treatment of patients exceeding that threshold. DESIGN:a) Retrospective study usin...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Claessens YE,Cariou A,Monchi M,Soufir L,Azoulay E,Rouges P,Goldgran-Toledano D,Branche F,Dhainaut JF

    更新日期:2003-04-01 00:00:00

  • Critical Care Management of Toxicities Associated With Targeted Agents and Immunotherapies for Cancer.

    abstract:OBJECTIVES:To describe the most common serious adverse effects and organ toxicities associated with emerging therapies for cancer that may necessitate admission to the ICU. DATA SOURCES AND STUDY SELECTION:PubMed and Medline search of relevant articles in English on the management of adverse effects of immunotherapy f...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审


    authors: Gutierrez C,McEvoy C,Munshi L,Stephens RS,Detsky ME,Nates JL,Pastores SM

    更新日期:2020-01-01 00:00:00

  • Sensitivity of routine intensive care unit surveillance for detecting myocardial ischemia.

    abstract:OBJECTIVE:To assess the effectiveness of routine intensive care unit surveillance compared with frequent 12-lead electrocardiogram monitoring for detecting electrocardiogram evidence suggestive of prolonged myocardial ischemia in vascular surgery patients. DESIGN:Prospective cohort trial. SETTING:Intensive care unit....

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Martinez EA,Kim LJ,Faraday N,Rosenfeld B,Bass EB,Perler BA,Williams GM,Dorman T,Pronovost PJ

    更新日期:2003-09-01 00:00:00

  • Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury.

    abstract:OBJECTIVE:To examine the effects of mechanical ventilation with a tidal volume of 6 mL/kg compared with 12 mL/kg predicted body weight on hemodynamics, vasopressor use, fluid balance, diuretics, sedation, and neuromuscular blockade within 48 hrs in patients with acute lung injury and acute respiratory distress syndrome...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Cheng IW,Eisner MD,Thompson BT,Ware LB,Matthay MA,Acute Respiratory Distress Syndrome Network.

    更新日期:2005-01-01 00:00:00

  • Clinical practice guidelines for the maintenance of patient physical safety in the intensive care unit: use of restraining therapies--American College of Critical Care Medicine Task Force 2001-2002.

    abstract:OBJECTIVE:To develop clinical practice guidelines for the use of restraining therapies to maintain physical and psychological safety of adult and pediatric patients in the intensive care unit. PARTICIPANTS:A multidisciplinary, multispecialty task force of experts in critical care practice was convened from the members...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审


    authors: Maccioli GA,Dorman T,Brown BR,Mazuski JE,McLean BA,Kuszaj JM,Rosenbaum SH,Frankel LR,Devlin JW,Govert JA,Smith B,Peruzzi WT,American College of Critical Care Medicine, Society of Critical Care Medicine.

    更新日期:2003-11-01 00:00:00

  • Exogenous interleukin-10 fails to decrease the mortality or morbidity of sepsis.

    abstract:OBJECTIVE:To determine if exogenous interleukin (IL)-10 will decrease the morbidity or mortality of sepsis induced by cecal ligation and puncture. DESIGN:Prospective, randomized, controlled study. SETTING:University research laboratory. SUBJECTS:Adult, female, Balb¿c mice. INTERVENTIONS:Balb¿c mice were subjected t...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Remick DG,Garg SJ,Newcomb DE,Wollenberg G,Huie TK,Bolgos GL

    更新日期:1998-05-01 00:00:00

  • High-Frequency Oscillatory Ventilation in Pediatric Acute Lung Injury: A Multicenter International Experience.

    abstract:OBJECTIVE:We aim to describe current clinical practice, the past decade of experience and factors related to improved outcomes for pediatric patients receiving high-frequency oscillatory ventilation. We have also modeled predictive factors that could help stratify mortality risk and guide future high-frequency oscillat...

    journal_title:Critical care medicine

    pub_type: 杂志文章,多中心研究


    authors: Rettig JS,Smallwood CD,Walsh BK,Rimensberger PC,Bachman TE,Bollen CW,Duval EL,Gebistorf F,Markhorst DG,Tinnevelt M,Todd M,Zurakowski D,Arnold JH

    更新日期:2015-12-01 00:00:00

  • Plasma aluminum concentrations in long-term mechanically ventilated patients receiving stress ulcer prophylaxis with sucralfate.

    abstract:OBJECTIVES:To determine plasma aluminum concentrations and 24-hr urine aluminum excretion rate in long-term mechanically ventilated patients treated with 6 g of sucralfate daily for stress ulcer prophylaxis. DESIGN:Prospective study in long-term mechanically ventilated critically ill patients. SETTING:A surgical inte...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章


    authors: Tryba M,Kurz-Müller K,Donner B

    更新日期:1994-11-01 00:00:00

  • Transient coagulation abnormalities after incompatible blood transfusion.

    abstract::This report describes an unusual hemolytic transfusion reaction. A group O donor was inadvertently transfused with 100 ml of group A red cells during the course of plasmapheresis. Granulocytopenia, thrombocytopenia, hypofibrinogenemia and low levels of factors V, VIII, and IX developed immediately after the infusion. ...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: McKenna PJ,Scheinman HZ

    更新日期:1975-01-01 00:00:00

  • One-lung high-frequency ventilation in the management of traumatic tear of bronchus in a child.

    abstract::An 8-yr-old child suffered traumatic bilateral pneumothoraces and a ruptured right main bronchus. Surgical repair of the bronchus was postponed for 18 h after a definite diagnosis was established due to severe hypoxemia and hypercarbia. Only left endobronchial high-frequency ventilation with muscle relaxation correcte...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Pizov R,Shir Y,Eimerl D,Uretzky G,Milgalter E,Cotev S

    更新日期:1987-12-01 00:00:00

  • Racial Differences in Palliative Care Use After Stroke in Majority-White, Minority-Serving, and Racially Integrated U.S. Hospitals.

    abstract:OBJECTIVES:Racial/ethnic differences in palliative care resource use after stroke have been recognized, but it is unclear whether patient or hospital characteristics drive this disparity. We sought to determine whether palliative care use after intracerebral hemorrhage and ischemic stroke differs between hospitals serv...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Faigle R,Ziai WC,Urrutia VC,Cooper LA,Gottesman RF

    更新日期:2017-12-01 00:00:00

  • Head computed tomography in medical intensive care unit patients: clinical indications.

    abstract:OBJECTIVE:To assess whether clinical variables might be useful in selecting patients who will have an acute intracranial abnormality seen in head computed tomographic scans (HCT). DESIGN:Retrospective study. SETTING:Medical intensive care unit (MICU) in a tertiary teaching hospital. MEASUREMENTS:Medical records of p...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Rafanan AL,Kakulavar P,Perl J 2nd,Andrefsky JC,Nelson DR,Arroliga AC

    更新日期:2000-05-01 00:00:00

  • How to perform indexing of extravascular lung water: a validation study.

    abstract:BACKGROUND:Extravascular lung water is a quantitative marker of the amount of fluid in the thoracic cavity besides the vasculature. Indexing to both predicted and actual body weight have been proposed to compare different individuals and provide a uniform range of normal. OBJECTIVE:We explored extravascular lung water...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Wolf S,Riess A,Landscheidt JF,Lumenta CB,Schürer L,Friederich P

    更新日期:2013-04-01 00:00:00

  • Phenotyping the Immune Response to Trauma: A Multiparametric Systems Immunology Approach.

    abstract:OBJECTIVE:Trauma induces a complex immune response that requires a systems biology research approach. Here, we used a novel technology, mass cytometry by time-of-flight, to comprehensively characterize the multicellular response to trauma. DESIGN:Peripheral blood mononuclear cells samples were stained with a 38-marker...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Seshadri A,Brat GA,Yorkgitis BK,Keegan J,Dolan J,Salim A,Askari R,Lederer JA

    更新日期:2017-09-01 00:00:00

  • Evaluation of an emergency cricothyrotomy instrument.

    abstract::An emergency cricothyrotomy device was placed in 11 anesthetized dogs in order to assess airway damage and problems in placement, ventilation, and design. Posterior airway perforation without esophageal damage occurred in three animals. Submucosal hematomas or cricoid cartilage injury occurred in seven animals. As pla...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Bjoraker DG,Kumar NB,Brown AC

    更新日期:1987-02-01 00:00:00

  • Impact of whole-body rehabilitation in patients receiving chronic mechanical ventilation.

    abstract:OBJECTIVE:To evaluate the prevalence and magnitude of weakness in patients receiving chronic mechanical ventilation and the impact of providing aggressive whole-body rehabilitation on conventional weaning variables, muscle strength, and overall functional status. DESIGN:Retrospective analysis of 49 consecutive patient...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Martin UJ,Hincapie L,Nimchuk M,Gaughan J,Criner GJ

    更新日期:2005-10-01 00:00:00

  • Evaluating the management of septic shock using patient simulation.

    abstract:OBJECTIVE:Develop a scoring system that can assess the management of septic shock by individuals and teams. DESIGN:Retrospective review of videotapes of critical care house staff managing a standardized simulation of septic shock. SETTING:Academic medical center; videotapes were made in a recreated intensive care uni...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Ottestad E,Boulet JR,Lighthall GK

    更新日期:2007-03-01 00:00:00

  • Assessment of hyperglycemia after calcium channel blocker overdoses involving diltiazem or verapamil.

    abstract:BACKGROUND:Overdoses of calcium channel blocker agents result in hyperglycemia, primarily due to the blockade of pancreatic L-type calcium channels and insulin resistance on the cellular level. The clinical significance of the hyperglycemia in this setting has not previously been described. METHODS:This study is a ret...

    journal_title:Critical care medicine

    pub_type: 杂志文章


    authors: Levine M,Boyer EW,Pozner CN,Geib AJ,Thomsen T,Mick N,Thomas SH

    更新日期:2007-09-01 00:00:00