Indirect calorimetry in mechanically ventilated infants and children: measurement accuracy with absence of audible airleak.

abstract：OBJECTIVE:Keratinocyte growth factor (KGF) is expressed primarily by fibroblasts, is important for alveolar epithelial proliferation/function, and protects against lung injury in multiple animal models. We wished to determine whether acute lung injury/acute respiratory distress syndrome (ALI/ARDS) alveolar fluid induce...

journal_title：Critical care medicine

authors： Chandel NS,Budinger GR,Mutlu GM,Varga J,Synenki L,Donnelly HK,Zirk A,Eisenbart J,Jovanovic B,Jain M

更新日期：2009-05-01 00:00:00

abstract：:Position of the CVP port on a flow-directed balloon-tip pulmonary arterial catheter affects the accuracy of both thermodilution cardiac output determinations and CVP measurements. Systemic allometry (the study of the growth of a part in relation to the total organism) has been used to determine an easily measured inde...

journal_title：Critical care medicine

authors： Borland LM

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:To determine whether any advantage exists using racemic epinephrine instead of the more potent and less expensive levo(1)-epinephrine in the treatment of postextubation laryngeal edema. DESIGN:Prospective, double-blind, randomized study. SETTING:Pediatric intensive care unit in a university teaching hospita...

journal_title：Critical care medicine

authors： Nutman J,Brooks LJ,Deakins KM,Baldesare KK,Witte MK,Reed MD

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVES:Excessive inflammation is closely related to severity and outcome of sepsis. Because interleukin-1-receptor-associated kinase 1 is a key signaling protein in the activation of NF-κB during infection, we aimed to evaluate the effect of functionally relevant haplotypes of IRAK1 on severity, development of acut...

journal_title：Critical care medicine

authors： Toubiana J,Courtine E,Pène F,Viallon V,Asfar P,Daubin C,Rousseau C,Chenot C,Ouaaz F,Grimaldi D,Cariou A,Chiche JD,Mira JP

更新日期：2010-12-01 00:00:00

abstract：:Simple insertion of a nasogastric (NG) tube was successful in only 52 of 100 anesthetized intubated patients. After the larynx was manually pulled forward, the NG tube was successfully inserted in 33 patients. In the remaining 15 patients, the NG tube was inserted only with the aid of a finger or a laryngoscope used w...

journal_title：Critical care medicine

authors： Perel A,Ya'ari Y,Pizov R

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of treatment with murine recombinant interleukin-1 beta on inflammatory infiltrate and tissue damage after experimental endotoxic challenge. DESIGN:Randomized, controlled study. SETTING:Experimental Unit, Virgen de las Nieves University Hospital. SUBJECTS:Seventy-two female CBA/H mic...

journal_title：Critical care medicine

authors： Téllez-Gil L,Mansilla-Roselló A,Collado-Torres A,Villar-del-Moral J,Garrote-Lara D,Villegas-Herrera T,Alvarez-Martín MJ,Ferrón-Orihuela JA

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:To evaluate knowledge translation after publication of the target temperature management 33°C versus 36°C after out-of-hospital cardiac arrest trial and associated patient outcomes. Our primary hypothesis was that target temperature management at 36°C was rapidly adopted in Australian and New Zealand ICUs. S...

journal_title：Critical care medicine

authors： Salter R,Bailey M,Bellomo R,Eastwood G,Goodwin A,Nielsen N,Pilcher D,Nichol A,Saxena M,Shehabi Y,Young P,Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation (ANZICS-CORE).

更新日期：2018-11-01 00:00:00

abstract：:We evaluated 95 extubated neonates to determine if certain risk factors could predict the development of laryngeal injury. Risk factors were recorded prospectively during the intubation period and correlated with laryngeal injury determined by laryngoscopy after extubation. Duration of intubation greater than or equal...

journal_title：Critical care medicine

authors： Fan LL,Flynn JW,Pathak DR

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:To review the reports of prolonged neuromuscular blockade secondary to vecuronium and atracurium administration. To propose mechanisms for prolonged blockade, as well as methods to avoid prolonged blockade. DATA SOURCES:A literature search was conducted of articles published from 1980 to 1993. Articles pert...

journal_title：Critical care medicine

authors： Watling SM,Dasta JF

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:A hallmark of amniotic fluid embolism is the induction of coagulation defects. Little is known about the nature of these defects or the causative agent or agents. The purpose of this study was to assess the effects of meconium containing (native) meconium-amniotic-fluid infusion (MAFI) and meconium-free (cent...

journal_title：Critical care medicine

authors： Petroianu GA,Altmannsberger SH,Maleck WH,Assmus HP,Friedberg C,Bergler WF,Rüfer R

更新日期：1999-02-01 00:00:00

abstract：:The use of epidural opioids for postoperative analgesia has been associated with respiratory depression. This report demonstrates the ability of nalbuphine to rapidly reverse the respiratory depression caused by epidural sufentanil while maintaining postoperative pain relief. ...

journal_title：Critical care medicine

authors： Cheng EY,May J

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:To test whether hospital-based physicians made different intensive care unit and life-sustaining treatment decisions for otherwise identical black and white patients with end-stage cancer and life-threatening hypoxia. DESIGN:We conducted a randomized trial of the relationship between patient race and physic...

journal_title：Critical care medicine

authors： Barnato AE,Mohan D,Downs J,Bryce CL,Angus DC,Arnold RM

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To determine whether low-dose dopamine administration reduces the incidence or severity of acute renal failure, need for dialysis, or mortality in patients with critical illness. DATA SOURCES AND STUDY SELECTION:We performed a MEDLINE search of literature published from 1966 to 2000 for studies addressing th...

journal_title：Critical care medicine

authors： Kellum JA,M Decker J

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To review current knowledge about the impact of prolonged mechanical ventilation on diaphragmatic function and biology. MEASUREMENTS:Systematic literature review. CONCLUSIONS:Prolonged mechanical ventilation can promote diaphragmatic atrophy and contractile dysfunction. As few as 18 hrs of mechanical ventil...

journal_title：Critical care medicine

authors： Powers SK,Kavazis AN,Levine S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:To determine whether delirium during ICU stay is associated with long-term mental health problems defined as symptoms of anxiety, depression, and posttraumatic stress disorder. DESIGN:Prospective cohort study. SETTING:Survey study, 1 year after discharge from a medical-surgical ICU in the Netherlands. PAT...

journal_title：Critical care medicine

authors： Wolters AE,Peelen LM,Welling MC,Kok L,de Lange DW,Cremer OL,van Dijk D,Slooter AJ,Veldhuijzen DS

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To investigate the interaction and involvement of hydrogen sulfide and transient receptor potential vanilloid type 1 in the pathogenesis of sepsis. Hydrogen sulfide has been demonstrated to be involved in many inflammatory states including sepsis. Its contribution in neurogenic inflammation has been suggested...

journal_title：Critical care medicine

authors： Ang SF,Moochhala SM,Bhatia M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to analyze the effect of the International Nosocomial Infection Control Consortium's multidimensional approach on the reduction of ventilator-associated pneumonia in patients hospitalized in intensive care units. DESIGN:A prospective active surveillance before-after study. The stud...

journal_title：Critical care medicine

authors： Rosenthal VD,Rodrigues C,Álvarez-Moreno C,Madani N,Mitrev Z,Ye G,Salomao R,Ulger F,Guanche-Garcell H,Kanj SS,Cuéllar LE,Higuera F,Mapp T,Fernández-Hidalgo R,INICC members.

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To assess whether paralysis alters pulmonary deposition of albuterol delivered by metered dose inhaler and spacer to small animals. DESIGN:A parallel group study of intubated and ventilated rabbits. INTERVENTIONS:Animals in group 1 (n = 7) were paralyzed with intravenous pancuronium, and ventilated at a rat...

journal_title：Critical care medicine

authors： Fok TF,al-Essa M,Monkman S,Dolovich M,Girard L,Coates G,Kirpalani H

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:Systemic inflammatory response occurs frequently after coronary artery bypass surgery, and it is strongly correlated with the risk of postoperative morbidity and mortality. Recent studies demonstrate that treatment with statin is associated with a significant and marked decrease in inflammation-associated va...

journal_title：Critical care medicine

authors： Chello M,Patti G,Candura D,Mastrobuoni S,Di Sciascio G,Agrò F,Carassiti M,Covino E

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:To evaluate partial occlusion in patients with pulmonary hypertension with regard to a) the degree to which it leads to overestimation of pulmonary artery occlusion pressure (Ppao) and b) identification of factors that could enhance its recognition. DESIGN:Observational descriptive study. SETTING:Medical in...

journal_title：Critical care medicine

authors： Leatherman JW,Shapiro RS

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a bolus infusion of diaspirin cross-linked hemoglobin (DCLHb or hemoglobin crosfumaril) on the ileal mucosal microcirculation in septic rats. DESIGN:Prospective, randomized, single-blinded study. SETTING:University-affiliated animal research laboratory. SUBJECTS:Twenty-four male ...

journal_title：Critical care medicine

authors： Sielenkämper AW,Eichelbrönner O,Martin CM,Madorin SW,Chin-Yee IH,Sibbald WJ

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:The antimetabolite drug, 5-fluorouracil, inhibits microbial growth. Coating of central venous catheters with 5-fluorouracil may reduce the risk of catheter infection. Our objective was to compare the safety and efficacy of central venous catheters externally coated with 5-fluorouracil with those coated with c...

journal_title：Critical care medicine

authors： Walz JM,Avelar RL,Longtine KJ,Carter KL,Mermel LA,Heard SO,5-FU Catheter Study Group.

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To review the institutional experience of a national tertiary referral center for extracorporeal life support (ECLS) in severe varicella pneumonia. DATA SOURCES:Hospital records and ECLS flow sheets. STUDY SELECTION:All pediatric (nonneonatal) and adult patients who were treated for varicella pneumonia with...

journal_title：Critical care medicine

authors： Lee WA,Kolla S,Schreiner RJ Jr,Hirschl RB,Bartlett RH

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVES:To determine the outcome of oxygen consumption (VO2) and energy expenditure after cessation of sedation in severe head-injured patients and to assess its usefulness as a predictor of neurologic severity. DESIGN:Prospective, descriptive study. SETTING:Neurosurgical intensive care unit (ICU) in a university ...

journal_title：Critical care medicine

authors： Bruder N,Lassegue D,Pelissier D,Graziani N,François G

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To determine whether mechanical ventilation using high tidal volume is associated with nonpulmonary organ dysfunction that can be attenuated by dexamethasone. DESIGN:Prospective randomized animal intervention study. SETTING:Animal care facility in a university hospital. SUBJECTS:Sedated and tracheostomized...

journal_title：Critical care medicine

authors： Nin N,Peñuelas O,de Paula M,Lorente JA,Fernández-Segoviano P,Esteban A

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:To track compliance by an interprofessional team with the Awakening and Breathing Coordination, Choice of drugs, Delirium monitoring and management, Early mobility, and Family engagement (ABCDEF) bundle in implementing the Pain, Agitation, and Delirium guidelines. The aim was to study the association between...

journal_title：Critical care medicine

authors： Barnes-Daly MA,Phillips G,Ely EW

更新日期：2017-02-01 00:00:00

abstract：:The effects of hypertonic mannitol on postischemic cerebral circulation were studied in 20 dogs. Mannitol, 2 g/kg iv, was infused into ten dogs during a 2-h period starting 1.5 h after 6 min of complete cerebral ischemia. One hour postischemia, regional cerebral blood flow (rCBF) was 36% in the control group (ten dogs...

journal_title：Critical care medicine

authors： Arai T,Tsukahara I,Nitta K,Watanabe T

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:Supplementation with tetrahydrobiopterin, a nitric oxide synthase cofactor, may reduce microvascular endothelial dysfunction in severe sepsis. We studied whether tetrahydrobiopterin administration exerts beneficial effects in an ovine septic shock model. DESIGN:Randomized animal study. SETTING:University ho...

journal_title：Critical care medicine

authors： He X,Su F,Velissaris D,Salgado DR,de Souza Barros D,Lorent S,Taccone FS,Vincent JL,De Backer D

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Acute renal failure remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of acute renal failure. Although the Duffy antigen receptor for chemokines (DARC) is present in several tissues and a highly specific ligand for vari...

journal_title：Critical care medicine

authors： Zarbock A,Schmolke M,Bockhorn SG,Scharte M,Buschmann K,Ley K,Singbartl K

更新日期：2007-09-01 00:00:00

abstract：:A patient with brainstem infarction met the clinical criteria for brain death but had persistent EEG activity, complicating our decision to withdraw life support. We evaluated cerebral blood flow with xenon-enhanced computed tomography (Xe/CT), which documented the absence of posterior circulation flow and persistent,...

journal_title：Critical care medicine

authors： Darby J,Yonas H,Brenner RP

更新日期：1987-05-01 00:00:00