Overestimation of pulmonary artery occlusion pressure in pulmonary hypertension due to partial occlusion.

abstract：:Suction applied to a chest-tube drainage system produces subambient pressure within the chest tube and may increase or decrease the flow of gas passing from the airway through a bronchopleural fistula. Such gas may have participated in gas exchange and contain more CO2 and less O2 than inspired gas. Calculated or meas...

journal_title：Critical care medicine

authors： Powner DJ,Cline CD,Rodman GH Jr

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the hypothesis that splanchnic ischemia and mucosal hypoxia are responsible for lipopolysaccharide-induced intramucosal acidosis in pigs. DESIGN:Prospective, randomized, unblinded study. SETTING:Surgical research laboratory at a large, university-affiliated medical center. SUBJECTS:Anesthetized...

journal_title：Critical care medicine

authors： VanderMeer TJ,Wang H,Fink MP

更新日期：1995-07-01 00:00:00

abstract：:A small, double-blind crossover study compared the efficacy of aminophylline and doxapram in ventilator weaning of eight premature infants recovering from respiratory distress syndrome (RDS). Although neither drug was significantly better than the other, four infants were weaned from mechanical ventilation after drug ...

journal_title：Critical care medicine

authors： Eyal FG,Sagi EF,Alpan G,Glick B,Arad I

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To determine the sensitivity, specificity, and predictive values of cultures done with blood drawn through a central venous or arterial catheter compared with peripheral venipuncture. DESIGN:Retrospective cohort study of critically ill surgical patients in whom samples for paired cultures were drawn through ...

journal_title：Critical care medicine

authors： Martinez JA,DesJardin JA,Aronoff M,Supran S,Nasraway SA,Snydman DR

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To review how endogenous protein C activation might change in disease states and to discuss the implications of these findings in the context of severe sepsis. DATA SOURCE:A review of the published literature in PubMed together with data from abstracts from 2001 to present. DATA EXTRACTION AND SYNTHESIS:Act...

journal_title：Critical care medicine

authors： Liaw PC

更新日期：2004-05-01 00:00:00

abstract：:The endothelium is a highly dynamic cell layer that is involved in a multitude of physiologic functions, including the control of vasomotor tone, the trafficking of cells and nutrients, the maintenance of blood fluidity, and the growth of new blood vessels. Over the past several decades, advances in basic research of ...

journal_title：Critical care medicine

authors： Aird WC

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Endotoxin (lipopolysaccharide [LPS]) has been associated with sepsis and the high mortality rate seen in septic shock. The administration of a small amount of LPS to healthy subjects produces a mild syndrome qualitatively similar to that seen in clinical sepsis. We used this model to test the efficacy of an ...

journal_title：Critical care medicine

authors： Bunnell E,Lynn M,Habet K,Neumann A,Perdomo CA,Friedhoff LT,Rogers SL,Parrillo JE

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and risk factors of chronic critical illness after severe blunt trauma. DESIGN:Prospective observational cohort study (NCT01810328). SETTING:Two level-one trauma centers in the United States. PATIENTS:One hundred thirty-five adult blunt trauma patients with hemorrhagic shock who ...

journal_title：Critical care medicine

authors： Mira JC,Cuschieri J,Ozrazgat-Baslanti T,Wang Z,Ghita GL,Loftus TJ,Stortz JA,Raymond SL,Lanz JD,Hennessy LV,Brumback B,Efron PA,Baker HV,Moore FA,Maier RV,Moldawer LL,Brakenridge SC

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of the selective alpha 1-adrenergic receptor agonist phenylephrine in the hemodynamic support of patients with septic shock. DESIGN:Retrospective analysis of clinical use of phenylephrine. SETTING:Surgical ICU in a university hospital. PATIENTS:Thirteen patients with septic shock (diagn...

journal_title：Critical care medicine

authors： Gregory JS,Bonfiglio MF,Dasta JF,Reilley TE,Townsend MC,Flancbaum L

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:Our understanding of the acute respiratory distress syndrome in children is limited, and literature is dominated by investigations in adult patients. Recent preclinical studies suggest that the susceptibility to and severity of acute respiratory distress syndrome in children could differ from that in adults....

journal_title：Critical care medicine

authors： Schouten LR,Veltkamp F,Bos AP,van Woensel JB,Serpa Neto A,Schultz MJ,Wösten-van Asperen RM

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To compare the impact of two different customization strategies in the performance of the admission Mortality Probability Model II (MPM II0) using formal statistical assessment. DESIGN:Analysis of the database of a multicenter, multinational, prospective cohort study, EURICUS-1, involving 89 intensive care u...

journal_title：Critical care medicine

authors： Moreno R,Apolone G

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that trauma-hemorrhagic shock (T/HS)-induced changes in red blood cells (RBC) contribute to the reduction of blood flow in distant organs. DESIGN:Laboratory study. SETTING:Academic medical center laboratory. SUBJECTS:Specific pathogen-free male Sprague-Dawley rats weighing between 25...

journal_title：Critical care medicine

authors： Machiedo GW,Zaets SB,Berezina TL,Xu DZ,Feketova E,Spolarics Z,Deitch EA

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To test the effects of three hemoglobin solutions on liver function and hepatic morphology after resuscitation from severe hemorrhagic shock. DESIGN:Prospective study. SETTING:Laboratory. SUBJECTS:Thirty-three beagle dogs. INTERVENTION:Hemorrhagic shock was induced in anesthetized dogs by removal of blood...

journal_title：Critical care medicine

authors： Eldridge J,Russell R,Christenson R,Sakamoto R,Williams J,Parr M,Trump B,Delaney P,Mackenzie CF

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To determine the effect that acute physiologic derangements have on outcome after subarachnoid hemorrhage (SAH) and to design a composite score summarizing these abnormalities. DESIGN:Prospective observational study. SETTING:Neuroscience intensive care unit in a tertiary care academic center. PATIENTS:Cons...

journal_title：Critical care medicine

authors： Claassen J,Vu A,Kreiter KT,Kowalski RG,Du EY,Ostapkovich N,Fitzsimmons BF,Connolly ES,Mayer SA

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:To determine the frequency of advance directives or directives disclosed by healthcare agents and their influence on decisions to withdraw/withhold life-sustaining care in neurocritically ill adults. DATA SOURCES:PubMed, Embase, and Cochrane databases. STUDY SELECTION:Screening was performed using predefin...

journal_title：Critical care medicine

authors： Sutter R,Meyer-Zehnder B,Baumann SM,Marsch S,Pargger H

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:In acute respiratory distress syndrome, conservative fluid management increases ventilator-free days without affecting mortality. Response to fluid management may differ based on patients' initial central venous pressure. We hypothesized that initial central venous pressure would modify the effect of fluid m...

journal_title：Critical care medicine

authors： Semler MW,Wheeler AP,Thompson BT,Bernard GR,Wiedemann HP,Rice TW,National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network.

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The antimetabolite drug, 5-fluorouracil, inhibits microbial growth. Coating of central venous catheters with 5-fluorouracil may reduce the risk of catheter infection. Our objective was to compare the safety and efficacy of central venous catheters externally coated with 5-fluorouracil with those coated with c...

journal_title：Critical care medicine

authors： Walz JM,Avelar RL,Longtine KJ,Carter KL,Mermel LA,Heard SO,5-FU Catheter Study Group.

更新日期：2010-11-01 00:00:00

abstract：:A 77-yr-old white man recovering from aortobiiliac bypass surgery suffered a sudden stroke within 30 min after carotid sinus massage was performed in an attempt to treat supraventricular tachycardia. Even though carotid digital subtraction angiography and angiograms were negative for carotid artery disease, we believe...

journal_title：Critical care medicine

authors： Bastulli JA,Orlowski JP

更新日期：1985-10-01 00:00:00

abstract：:We compared the blood culture results obtained either by venipuncture or through an arterial catheter in 51 critically ill patients with 217 clinically suspected episodes of bacteremia. During each episode, three blood culture samples, two arterial and one venous, were drawn within 1 h. One or more cultures were posit...

journal_title：Critical care medicine

authors： Väisänen IT,Michelsen T,Valtonen V,Mäkeläinen A

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:To examine variations in case-mix, structure, resource use, and outcome performance among teaching and nonteaching intensive care units (ICU). DESIGN:Prospective inception cohort study. PATIENTS:A consecutive sample of 15,297 patients at 35 hospitals, which compared 8,269 patients admitted to 20 teaching IC...

journal_title：Critical care medicine

authors： Zimmerman JE,Shortell SM,Knaus WA,Rousseau DM,Wagner DP,Gillies RR,Draper EA,Devers K

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether changing heat and moisture exchangers (HMEs) every 96 hrs rather than 24 hrs would affect their efficacy to preserve the heat and moisture of inspiratory gases. The impact of a prolonged use of the HME on its microbial colonization was also assessed. DESIGN:Pros...

journal_title：Critical care medicine

authors： Thomachot L,Boisson C,Arnaud S,Michelet P,Cambon S,Martin C

更新日期：2000-03-01 00:00:00

abstract：:Eleven cases of renal failure associated with resection of ruptured abdominal aortic aneurysm and requiring hemodialysis are reported. Previously described series have emphasized the extremely high mortality rate in such patients. In our clinical experience, however, 8 of 11 consecutively treated patients with this cl...

journal_title：Critical care medicine

authors： Sapir DG,Dandy WE Jr,Whelton A,Cooke CR

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVE:To test the hypotheses that, for uncontrolled hemorrhagic shock (UHS) in rats, mild hypothermia, compared with normothermia, would increase long-term survival as well as moderate hypothermia, oxygen breathing would increase survival further, and hypothermia and oxygen would mitigate visceral ischemia (dysoxia...

journal_title：Critical care medicine

authors： Takasu A,Stezoski SW,Stezoski J,Safar P,Tisherman SA

更新日期：2000-07-01 00:00:00

abstract：CONTEXT:Reducing aspiration of gastric contents by placing mechanically ventilated patients in a semirecumbent position has been associated with lower incidences of ventilator-associated pneumonia (VAP). The feasibility and efficacy of this intervention in a larger patient population, however, are unknown. OBJECTIVE:A...

journal_title：Critical care medicine

authors： van Nieuwenhoven CA,Vandenbroucke-Grauls C,van Tiel FH,Joore HC,van Schijndel RJ,van der Tweel I,Ramsay G,Bonten MJ

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVES:Mild decrease in core temperature (therapeutic hypothermia) provides lasting neuroprotection following cardiac arrest or cerebral ischemia. However, current methods for producing therapeutic hypothermia trigger a cold-defense response that must be countered by sedatives, muscle paralytics, and mechanical ven...

journal_title：Critical care medicine

authors： Feketa VV,Zhang Y,Cao Z,Balasubramanian A,Flores CM,Player MR,Marrelli SP

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:Catheter-associated infections are common, costly, and potentially lethal. The impact of catheter insertion site on infection risk remains controversial. We aimed to establish whether nontunneled central venous catheters inserted in the subclavian vein are associated with lower risk of catheter-associated inf...

journal_title：Critical care medicine

authors： Parienti JJ,du Cheyron D,Timsit JF,Traoré O,Kalfon P,Mimoz O,Mermel LA

更新日期：2012-05-01 00:00:00

abstract：:PEEP is the most important therapeutic intervention in the management of acute respiratory failure. Transitory PEEP disconnection to perform clinically relevant maneuvers is often necessary, but its effect upon PaO2 and physiological shunt in patients requiring high-level PEEP is not clear from the literature. Nine ad...

journal_title：Critical care medicine

authors： De Campo T,Civetta JM

更新日期：1979-02-01 00:00:00

abstract：:The current investigation describes the morphological and pathophysiological effects of stroma-free hemoglobin solution (SFH) on the liver and kidney. One h after a 75% blood volume exchange in animals receiving 7% SFH, hepatic morphology was normal. Animals whose blood was similarly exchanged with 7% albumin demonstr...

journal_title：Critical care medicine

authors： Friedman HI,DeVenuto F

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between acute adrenergic stress, plasma catecholamine concentrations, and beta 2-adrenergic receptors. DESIGN:Prospective, descriptive study. SETTING:Emergency medical service at a university hospital. PATIENTS:Twenty-seven patients with out-of-hospital cardiac arrest (n = 11),...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Anhäupl T,Trunk E,Georgieff M,Lurie KG

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVES:Systemic inflammatory response occurs frequently after coronary artery bypass surgery, and it is strongly correlated with the risk of postoperative morbidity and mortality. Recent studies demonstrate that treatment with statin is associated with a significant and marked decrease in inflammation-associated va...

journal_title：Critical care medicine

authors： Chello M,Patti G,Candura D,Mastrobuoni S,Di Sciascio G,Agrò F,Carassiti M,Covino E

更新日期：2006-03-01 00:00:00