Experience with phenylephrine as a component of the pharmacologic support of septic shock.

abstract：OBJECTIVES:Light chains κ and λ are immunoglobulin constituents but also circulate independently in blood as free light chains. We investigated whether a concomitant abnormality in free light chain and immunoglobulin levels could identify a high risk of death sepsis subpopulation to inform future IV immunoglobulin tria...

journal_title：Critical care medicine

authors： Shankar-Hari M,Singer M,Spencer J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To examine the effect of hypertonic saline on bacterial translocation and the number and function of natural killer and T cells in controlled hemorrhagic shock. DESIGN:Randomized controlled study. Duration of follow-up was 24 hrs. SETTING:University research laboratory. SUBJECTS:Adult male Sprague-Dawley r...

journal_title：Critical care medicine

authors： Hirsh M,Dyugovskaya L,Bashenko Y,Krausz MM

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical utility of right ventricular end-diastolic volume index (RVEDVI) and pulmonary artery occlusion pressure (PAOP) as measures of preload status in patients with acute respiratory failure receiving treatment with positive end-expiratory pressure. DESIGN:Prospective, cohort study. SETTI...

journal_title：Critical care medicine

authors： Cheatham ML,Nelson LD,Chang MC,Safcsak K

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of spontaneous gasping on cardiorespiratory functions and the ability to resuscitate during experimental cardiac arrest. DATA SOURCES:Studies in rat and pig models during cardiac arrest and cardiopulmonary resuscitation (CPR). STUDY SELECTION:We retrospectively examined the role of sp...

journal_title：Critical care medicine

authors： Yang L,Weil MH,Noc M,Tang W,Turner T,Gazmuri RJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition. DESIGN:Prospective, randomized clinical trial. SETTING:Department of surgery in a university hospital. PATIENTS:Two hundred and fifty-seven patients with cancer of the stomach (n = 1...

journal_title：Critical care medicine

authors： Braga M,Gianotti L,Gentilini O,Parisi V,Salis C,Di Carlo V

更新日期：2001-02-01 00:00:00

abstract：:In a prospective randomized study to determine whether prevention of colonization of Gram-negative bacteria results in prevention of Gram-negative bacterial infections, 96 intensive care patients were randomly allocated into a control group and a study group. The study group received oral nonabsorbable antimicrobial a...

journal_title：Critical care medicine

authors： Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:Clinical predictors for acute respiratory distress syndrome (ARDS) have been studied in few prospective studies. Although transfusions are common in the intensive care unit, the role of submassive transfusion in non-trauma-related ARDS has not been studied. We describe here the clinical predictors of ARDS ris...

journal_title：Critical care medicine

authors： Gong MN,Thompson BT,Williams P,Pothier L,Boyce PD,Christiani DC

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Transarterial chemoembolization is a widely used therapy for the treatment of hepatocellular carcinoma. A rare adverse event is acute respiratory distress syndrome from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure. The objective of this report is to describe an atypi...

journal_title：Critical care medicine

authors： Taupin D,Mukherjee V,Nathavitharana R,Green DA,Fridman D

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To study the effect of early and continuous venovenous hemofiltration (CVVH) on the plasma concentrations of several humoral mediators of inflammation and subsequent organ dysfunction in septic patients. DESIGN:Randomized, controlled trial. SETTING:Intensive care unit of a tertiary hospital. PATIENTS:Twent...

journal_title：Critical care medicine

authors： Cole L,Bellomo R,Hart G,Journois D,Davenport P,Tipping P,Ronco C

更新日期：2002-01-01 00:00:00

abstract：:Trauma is the leading cause of both morbidity and mortality in the pediatric population, and traumatic injury causes > 50% of all childhood deaths. Significant mortality rates have been reported for children with traumatic brain injury. Although children have better survival rates as compared with adults with traumati...

journal_title：Critical care medicine

authors： Mazzola CA,Adelson PD

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To determine the frequency, etiology, and risk factors of ventilator-associated pneumonia (VAP) and purulent tracheobronchitis (TBX) in patients who have undergone heart surgery. To study the predictive role of systematic surveillance cultures. DESIGN:Prospective study. SETTING:Heart surgery intensive care ...

journal_title：Critical care medicine

authors： Bouza E,Pérez A,Muñoz P,Jesús Pérez M,Rincón C,Sánchez C,Martín-Rabadán P,Riesgo M,Cardiovascular Infection Study Group.

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:We sought to review findings from recent literature on the postresuscitation care of cardiac arrest patients using therapeutic hypothermia as part of nontrial treatment. DESIGN:Literature review. SETTING:Hospital-based environment. SUBJECTS:Patients initially resuscitated from cardiac arrest who underwent...

journal_title：Critical care medicine

authors： Sagalyn E,Band RA,Gaieski DF,Abella BS

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:Radiographic criteria for acute respiratory distress syndrome have been criticized for poor reliability. Our objective was to test an educational intervention to improve the radiographic identification of acute respiratory distress syndrome by participants in the Large Observational Study to Understand the G...

journal_title：Critical care medicine

authors： Goddard SL,Rubenfeld GD,Manoharan V,Dev SP,Laffey J,Bellani G,Pham T,Fan E

更新日期：2018-05-01 00:00:00

abstract：:Serum ionized calcium (Ca+2), creatinine, magnesium, phosphate, and arterial pH were measured in patients on admission to the medical ICU (MICU). Patients were classified into three groups: a) hypotensive (n = 38), those who received vasopressor support for frank hypotension; b) hypertensive (n = 21), those who requir...

journal_title：Critical care medicine

authors： Desai TK,Carlson RW,Thill-Baharozian M,Geheb MA

更新日期：1988-06-01 00:00:00

abstract：:Ten infants with acquired subglottic stenosis were treated successfully using the anterior cricoid split operation. Eight had been preterm infants who required endotracheal intubation and assisted ventilation for the respiratory distress syndrome. Two had been born at term; 1 required mechanical ventilation for aspira...

journal_title：Critical care medicine

authors： Frankel LR,Anas NG,Perkin RM,Seid AB,Peterson B,Park SM

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVES:Thrombotic microangiopathy syndromes are a heterogeneous group of severe diseases that often require ICU admission. Prompt initiation of targeted therapies is required for atypical hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, whereas there is no specific consensus therapy for Shiga toxi...

journal_title：Critical care medicine

authors： Joseph A,Rafat C,Zafrani L,Mariani-Kurkdjian P,Veyradier A,Hertig A,Rondeau E,Mariotte E,Azoulay E

更新日期：2018-09-01 00:00:00

abstract：:Checklists have been recently promulgated as a method to enhance patient safety and improve outcomes for critically ill patients. Specifically, recent work performed by researchers from the Johns Hopkins Medical Institutions has demonstrated that the addition of checklists to usual care in the intensive care unit is a...

journal_title：Critical care medicine

authors： Savel RH,Goldstein EB,Gropper MA

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the methodological quality and thematic completeness of existing clinical practice guidelines, addressing early mobilization of adults in the ICU. DATA SOURCES:Systematic review of Medline, Embase, CINAHL, Cochrane, and grey literature from January 2008 to February 2020. STUDY SELECTION:Two rev...

journal_title：Critical care medicine

authors： Lang JK,Paykel MS,Haines KJ,Hodgson CL

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To assess the influence of private attending physician status on the withdrawal of life-sustaining interventions among patients dying within a medical intensive care unit (ICU). DESIGN:Retrospective cohort analysis. SETTING:An academic tertiary care center. PATIENTS:One hundred fifty-nine consecutive patie...

journal_title：Critical care medicine

authors： Kollef MH

更新日期：1996-06-01 00:00:00

abstract：:Little is known about the structure and objectives of various hospital ethics committees due to their need to preserve confidentiality, their reluctance to reveal internal hospital problems, and their concern about becoming involved in the developing debate about the appropriate role and value of such committees. The ...

journal_title：Critical care medicine

authors： Cohen CB

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVES:To define a curriculum that outlines the core knowledge residents should possess upon completion of graduate training in order to be able to formulate and initiate a treatment plan for the critically ill patient. DATA SOURCES:Requirements for training program certification as outlined by the Accreditation C...

journal_title：Critical care medicine

authors：

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between acute adrenergic stress, plasma catecholamine concentrations, and beta 2-adrenergic receptors. DESIGN:Prospective, descriptive study. SETTING:Emergency medical service at a university hospital. PATIENTS:Twenty-seven patients with out-of-hospital cardiac arrest (n = 11),...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Anhäupl T,Trunk E,Georgieff M,Lurie KG

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Goal-directed nutritional support is essential to improving morbidity and mortality. Open abdominal decompression is similarly crucial to the successful treatment of intra-abdominal hypertension and abdominal compartment syndrome. The open abdomen, however, places the patient at risk for potentially significa...

journal_title：Critical care medicine

authors： Cheatham ML,Safcsak K,Brzezinski SJ,Lube MW

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Under "Rory's Regulations," New York State Article 28 acute care hospitals were mandated to implement sepsis protocols and report patient-level data. This study sought to determine how well cases reported under state mandate align with discharge records in a statewide administrative database. DESIGN:Observa...

journal_title：Critical care medicine

authors： Prescott HC,Cope TM,Gesten FC,Ledneva TA,Friedrich ME,Iwashyna TJ,Osborn TM,Seymour CW,Levy MM

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To compare silver-coated and uncoated central venous catheters regarding bacterial colonization. To assess the relative contribution of catheter hub and skin colonization to catheter tip colonization. DESIGN:Prospective, randomized clinical trial. SETTING:Intensive care unit in a university hospital. PATIE...

journal_title：Critical care medicine

authors： Bach A,Eberhardt H,Frick A,Schmidt H,Böttiger BW,Martin E

更新日期：1999-03-01 00:00:00

abstract：:We compared the blood culture results obtained either by venipuncture or through an arterial catheter in 51 critically ill patients with 217 clinically suspected episodes of bacteremia. During each episode, three blood culture samples, two arterial and one venous, were drawn within 1 h. One or more cultures were posit...

journal_title：Critical care medicine

authors： Väisänen IT,Michelsen T,Valtonen V,Mäkeläinen A

更新日期：1985-08-01 00:00:00

abstract：:Paranasal sinusitis is reported as a complication of prolonged nasal intubation and the source of sepsis in adult intensive care patients. In surgical neonates with congenital malformations, prolonged intubation with a nasotracheal (NT) or NG tube is often necessary, but sinusitis with complicating sepsis is seldom re...

journal_title：Critical care medicine

authors： Bos AP,Tibboel D,Hazebroek FW,Hoeve H,Meradji M,Molenaar JC

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVES:To compare 1-year all-cause mortality and major adverse cardiovascular events in cardiac arrest survivors with and without posttraumatic stress disorder symptomatology at hospital discharge. DESIGN:Prospective, observational cohort. SETTING:ICUs at a tertiary-care center. PATIENTS:Adults with return of sp...

journal_title：Critical care medicine

authors： Agarwal S,Presciutti A,Cornelius T,Birk J,Roh DJ,Park S,Claassen J,Elkind MSV,Edmondson D

更新日期：2019-06-01 00:00:00

abstract：:High-risk patients who survived general (noncardiac) surgery were observed to have cardiac index (CI) values averaging 4.5 L/min.m2, oxygen delivery (DO2) greater than 600 ml/min.m2, and oxygen consumption (VO2) 170 ml/min.m2 during the first 2 or three days postoperatively. Patients who subsequently died maintained r...

journal_title：Critical care medicine

authors： Shoemaker WC,Kram HB,Appel PL

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:To describe the effectiveness of a comprehensive, interdisciplinary sepsis treatment protocol with regard to both implementation and outcomes and to compare the mortality rates and therapies of patients with septic shock with similar historical controls. DESIGN:Prospective, interventional cohort study with ...

journal_title：Critical care medicine

authors： Shapiro NI,Howell MD,Talmor D,Lahey D,Ngo L,Buras J,Wolfe RE,Weiss JW,Lisbon A

更新日期：2006-04-01 00:00:00