Development and application of a double-piston configured, total-liquid ventilatory support device.

abstract：OBJECTIVE:An increasing number of ICU patients survive and develop mental, cognitive, or physical impairments. Various interventions support recovery from this postintensive care syndrome. Physicians in charge of post-ICU patients need to know which interventions are effective. DATA SOURCES:Systematic literature searc...

journal_title：Critical care medicine

authors： Mehlhorn J,Freytag A,Schmidt K,Brunkhorst FM,Graf J,Troitzsch U,Schlattmann P,Wensing M,Gensichen J

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To explore the potential value of heart rate variability features for automated monitoring of sedation levels in mechanically ventilated ICU patients. DESIGN:Multicenter, pilot study. SETTING:Several ICUs at Massachusetts General Hospital, Boston, MA. PATIENTS:Electrocardiogram recordings from 40 mechanica...

journal_title：Critical care medicine

authors： Nagaraj SB,McClain LM,Zhou DW,Biswal S,Rosenthal ES,Purdon PL,Westover MB

更新日期：2016-09-01 00:00:00

abstract：:The definition of sepsis has been recently modified to accommodate emerging knowledge in the field, while at the same time being recognized as challenging, if not impossible, to define. Here, we seek to clarify the current understanding of sepsis as one that has been typically framed as a disorder of inflammation to o...

journal_title：Critical care medicine

authors： Alverdy JC,Krezalek MA

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:To determine whether mean arterial blood pressure excursions below the lower limit of cerebral blood flow autoregulation during cardiopulmonary bypass are associated with acute kidney injury after surgery. SETTING:Tertiary care medical center. PATIENTS:Four hundred ten patients undergoing cardiac surgery w...

journal_title：Critical care medicine

authors： Ono M,Arnaoutakis GJ,Fine DM,Brady K,Easley RB,Zheng Y,Brown C,Katz NM,Grams ME,Hogue CW

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:Carbon monoxide poisoning affects 50,000 per year in the United States alone. Mortality is approximately 3%, and up to 40% of survivors suffer from permanent neurocognitive and affective deficits. Hyperbaric oxygen therapy has shown benefit on reducing the long-term neurologic sequelae of carbon monoxide poi...

journal_title：Critical care medicine

authors： Rose JJ,Nouraie M,Gauthier MC,Pizon AF,Saul MI,Donahoe MP,Gladwin MT

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the frequency of unsuspected posterior vessel wall penetration of the internal jugular vein during ultrasound-guided needle cannulation. DESIGN:Prospective, single-blinded observational study. SETTING:Urban level I emergency department with an annual census of 80,000. PATIENTS:Residents who ha...

journal_title：Critical care medicine

authors： Blaivas M,Adhikari S

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To assess the impact of sepsis classification and multidrug-resistance status on outcome in patients receiving appropriate initial antibiotic therapy. DESIGN:A retrospective cohort study. SETTING:Barnes-Jewish Hospital, a 1,250-bed teaching hospital. PATIENTS:Individuals with Enterobacteriaceae sepsis, sev...

journal_title：Critical care medicine

authors： Burnham JP,Lane MA,Kollef MH

更新日期：2015-08-01 00:00:00

abstract：:The hemodynamic effects of digitalis were examined in ten patients with acute cardiac failure. Administration of 10 micrograms/kg of digoxin iv resulted in significant increases in cardiac index, stroke volume index, and left ventricular stroke work index within one hour in five patients with acute myocardial infarcti...

journal_title：Critical care medicine

authors： Rackow EC,Packman MI,Weil MH

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVES:Sepsis remains a serious clinical problem despite intensive research efforts and numerous attempts to improve outcome by modifying the inflammatory response. Substance P, the principal ligand for the neurokinin-1 receptor, is a potent proinflammatory mediator that exacerbates inflammatory responses and cardi...

journal_title：Critical care medicine

authors： Mella JR,Chiswick E,Stepien D,Moitra R,Duffy ER,Stucchi A,Remick D

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Catheter-associated infections are common, costly, and potentially lethal. The impact of catheter insertion site on infection risk remains controversial. We aimed to establish whether nontunneled central venous catheters inserted in the subclavian vein are associated with lower risk of catheter-associated inf...

journal_title：Critical care medicine

authors： Parienti JJ,du Cheyron D,Timsit JF,Traoré O,Kalfon P,Mimoz O,Mermel LA

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To investigate the interrelationship between cardiac surgery, age, circulating concentrations of the vitamin D hormone 1,25-dihydroxyvitamin D, and clinical outcome. DESIGN:Prospective, monocentric, two-arm parallel study. SETTING:Tertiary Heart and Diabetes Center in the Federal State of North Rhine-Westph...

journal_title：Critical care medicine

authors： Börgermann J,Lazouski K,Kuhn J,Dreier J,Schmidt M,Gilis-Januszewski T,Knabbe C,Gummert JF,Zittermann A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To determine whether naloxone administration after hemorrhagic shock has any beneficial or deleterious effect on immune responses. BACKGROUND DATA:Hemorrhagic shock is known to produce immunodepression in both humans and experimental animals. Although studies suggest that endogenous opioids play a role in im...

journal_title：Critical care medicine

authors： Wichmann MW,Zellweger R,Ayala A,Chaudry IH

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Although the development of ventilator-associated pneumonia (VAP) is assumed to increase costs of intensive care unit stay, it is unknown whether prevention of VAP by means of oropharyngeal decontamination is cost-effective. Because of wide ranges of individual patient costs, crude cost comparisons did not sh...

journal_title：Critical care medicine

authors： van Nieuwenhoven CA,Buskens E,Bergmans DC,van Tiel FH,Ramsay G,Bonten MJ

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. DESIGN:Retrospective study. SETTING:All adu...

journal_title：Critical care medicine

authors： Lee HY,Chen CL,Wu SR,Huang CW,Chiu CH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To determine the effect that acute physiologic derangements have on outcome after subarachnoid hemorrhage (SAH) and to design a composite score summarizing these abnormalities. DESIGN:Prospective observational study. SETTING:Neuroscience intensive care unit in a tertiary care academic center. PATIENTS:Cons...

journal_title：Critical care medicine

authors： Claassen J,Vu A,Kreiter KT,Kowalski RG,Du EY,Ostapkovich N,Fitzsimmons BF,Connolly ES,Mayer SA

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To measure patients' risk for acquiring antibiotic-resistant microorganisms associated with intensive care unit admission. DESIGN:Prospective, observational study. SETTING:Ten public hospitals including one university medical center. PATIENTS:Consecutive patients admitted to ten intensive care units. INTE...

journal_title：Critical care medicine

authors： Ho PL,Hong Kong intensive care unit antimicrobial resistance study (HK-ICARE) Group.

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:To investigate aortic functional alterations in the acute phase of aneurysmal subarachnoid hemorrhage and to evaluate the relationship between potential cardiovascular alterations and delayed cerebral infarctions or poor Glasgow Outcome Scale score at discharge from critical care unit. DESIGN:Prospective ob...

journal_title：Critical care medicine

authors： Papanikolaou J,Makris D,Karakitsos D,Saranteas T,Karabinis A,Kostopanagiotou G,Zakynthinos E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Opioids are frequently used during mechanical ventilation for severe viral infection in infancy. Opioid receptors have immunomodulatory properties, but nothing is known about their antiviral effects. We therefore aimed to investigate the role of opioid receptors in virus-induced airway inflammation. PATIENTS...

journal_title：Critical care medicine

authors： Salimi V,Hennus MP,Mokhtari-Azad T,Shokri F,Janssen R,Hodemaekers HM,Rygiel TP,Coenjaerts FE,Meyaard L,Bont L

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To assess protective and risk factors for mortality among pediatric patients during initial care after hematopoietic stem cell transplantation (HSCT) and to evaluate changes in hospital mortality. DESIGN:Retrospective cohort using the 1997, 2000, and 2003 Kids Inpatient Database, a probabilistic sample of ch...

journal_title：Critical care medicine

authors： Bratton SL,Van Duker H,Statler KD,Pulsipher MA,McArthur J,Keenan HT

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:The relationship between respiratory mechanical parameters and hemodynamic variables remains unclear. This study was performed to determine whether mean airway pressure and central venous pressure in the first day of mechanical ventilation are associated with patient outcomes. DESIGN:Retrospective first 24-...

journal_title：Critical care medicine

authors： Long Y,Su L,Zhang Q,Zhou X,Wang H,Cui N,Chai W,Wang X,Rui X,Liu D

更新日期：2017-05-01 00:00:00

abstract：:The resolution time of pneumothorax in neonates requiring tube thoracotomy is not known. We found that 28%, 50%, and 83% of 54 pneumothoraces in 40 neonates resolved within 24, 96, and 168 h of tube thoracotomy, respectively. Pneumothoraces that persisted beyond 168 h were in infants requiring ventilatory assistance. ...

journal_title：Critical care medicine

authors： Bhatia J,Mathew OP

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:Ventilator-associated pneumonia diagnosis remains a debatable topic. New definitions of ventilator-associated conditions involving worsening oxygenation have been recently proposed to make surveillance of events possibly linked to ventilator-associated pneumonia as objective as possible. The objective of the...

journal_title：Critical care medicine

authors： Damas P,Frippiat F,Ancion A,Canivet JL,Lambermont B,Layios N,Massion P,Morimont P,Nys M,Piret S,Lancellotti P,Wiesen P,D'orio V,Samalea N,Ledoux D

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To compare the effects of two lung-protective ventilation strategies on pulmonary vascular mechanics in early acute respiratory distress syndrome. DESIGN:Experimental study. SETTING:University animal research laboratory. SUBJECTS:Twelve pigs (30.8 ± 2.5 kg). INTERVENTIONS:Acute respiratory distress syndr...

journal_title：Critical care medicine

authors： Santos A,Gomez-Peñalver E,Monge-Garcia MI,Retamal J,Borges JB,Tusman G,Hedenstierna G,Larsson A,Suarez-Sipmann F

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Intensive care unit (ICU) length of stay (LOS) and hospital LOS are common indices used to compare performance of hospitals and are yardsticks used in efforts to contain costs, yet there is no standardized method of quantitating this outcome variable. Attempts have been made to correct LOS according to diseas...

journal_title：Critical care medicine

authors： Marik PE,Hedman L

更新日期：2000-06-01 00:00:00

abstract：:Instantaneous heart rate, indices of long-term and short-term heart-rate variability (HRV), and transcutaneous O2 (PtcO2) and CO2 (PtcCO2) tensions were recorded simultaneously on 164 occasions in 16 neonates. There was significant inverse correlation between PtcCO2 and both HRV indices, while no linear correlation wa...

journal_title：Critical care medicine

authors： Aärimaa T,Kero P,Välimäki I

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:The acute respiratory distress syndrome may complicate postpartum hemorrhagic shock and resuscitation, but its mechanisms are not yet well defined. We studied the lung inflammatory response to postpartum hemorrhagic shock and resuscitation in a rabbit model and the role of the nuclear factor-κB pathway. DESI...

journal_title：Critical care medicine

authors： Sheng C,Yu YH,Zhao KS,Huang LP,Lodato RF,Wang ZJ,Wang CH,Wang SH,Zha DS

更新日期：2012-05-01 00:00:00

abstract：:With the thermodilution technique, repeated determination of cardiac index (CI) has become a rapid, easily accomplished, safe procedure. We paired 77 CI determinations measured by direct Fick and thermodilution techniques in 21 patients who underwent myocardial revascularization. Commercially available thermistor-tipp...

journal_title：Critical care medicine

authors： Hodges M,Downs JB,Mitchell LA

更新日期：1975-09-01 00:00:00

abstract：OBJECTIVES:: To characterize the epidemiology and burden of early-onset, nonnosocomial candidemia. DESIGN:: Retrospective review of Cardinal Health Outcomes Research Database, which comprises all acute care admissions at participating hospitals. SETTING:: A total of 176 acute care hospitals. PATIENTS:: All patients ...

journal_title：Critical care medicine

authors： Shorr AF,Gupta V,Sun X,Johannes RS,Spalding J,Tabak YP

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To describe the dark side of pediatric intensive care fellowship training and offer educational approaches for understanding feelings of fallibility, anger, frustration, and loss. DATA SOURCES:Listening and observing fellows in the courses of their pediatric intensive care training and later careers. STUDY SE...

journal_title：Critical care medicine

authors： Jellinek MS,Todres ID,Catlin EA,Cassem EH,Salzman A

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVES:To determine the rate of unplanned PICU readmissions, examine the characteristics of index admissions associated with readmission, and compare outcomes of readmissions versus index admissions. DESIGN:Retrospective cohort analysis. SETTING:Ninety North American PICUs that participated in the Virtual Pediatr...

journal_title：Critical care medicine

authors： Edwards JD,Lucas AR,Stone PW,Boscardin WJ,Dudley RA

更新日期：2013-12-01 00:00:00