Thermodilution and Fick cardiac index determinations following cardiac surgery.

abstract：OBJECTIVES:To assess the relations between anemia, serum erythropoietin (EPO), iron status, and inflammatory mediators in multiply traumatized patients. DESIGN:Prospective observational study. SETTING:Intensive care unit. PATIENTS:Twenty-three patients suffering from severe trauma (injury severity score > or =30). ...

journal_title：Critical care medicine

authors： Hobisch-Hagen P,Wiedermann F,Mayr A,Fries D,Jelkmann W,Fuchs D,Hasibeder W,Mutz N,Klingler A,Schobersberger W

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To examine the effects of hypertonic (7.5%) saline-6% dextran 70 (HSD) and isotonic (0.9%) saline-6% dextran 70 (ISD) on cardiovascular function and intestinal perfusion in experimental endotoxin shock. DESIGN:Experimental, randomized, unblinded, interventional study. SETTING:University experimental animal ...

journal_title：Critical care medicine

authors： Oi Y,Aneman A,Svensson M,Ewert S,Dahlqvist M,Haljamäe H

更新日期：2000-08-01 00:00:00

abstract：:As of October 1985, 37 candidates have passed the final examination in intensive care for the Diploma of Fellow of the Faculty of Anaesthetists, Royal Australasian College of Surgeons (FFARACS). In September 1984, 23 of these successful candidates responded to a questionnaire seeking information on their educational e...

journal_title：Critical care medicine

authors： Byth PL,Harrison GA

更新日期：1986-06-01 00:00:00

abstract：:Right ventricular size and contractility were evaluated using two-dimensional echocardiography during the first days of respiratory support in 23 patients requiring mechanical ventilation for acute respiratory failure. Nine patients had normal echocardiographic right ventricular function, and nine other patients had a...

journal_title：Critical care medicine

authors： Jardin F,Gueret P,Dubourg O,Farcot JC,Margairaz A,Bourdarias JP

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness and safety of the hemoglobin-based nitric oxide scavenger, pyridoxalated hemoglobin polyoxyethylene, against placebo in patients with vasopressor-dependent distributive shock. DESIGN:Multicenter, randomized, placebo-controlled, open-label study. SETTING:Sixty-one participating I...

journal_title：Critical care medicine

authors： Vincent JL,Privalle CT,Singer M,Lorente JA,Boehm E,Meier-Hellmann A,Darius H,Ferrer R,Sirvent JM,Marx G,DeAngelo J

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To study the effect of early and continuous venovenous hemofiltration (CVVH) on the plasma concentrations of several humoral mediators of inflammation and subsequent organ dysfunction in septic patients. DESIGN:Randomized, controlled trial. SETTING:Intensive care unit of a tertiary hospital. PATIENTS:Twent...

journal_title：Critical care medicine

authors： Cole L,Bellomo R,Hart G,Journois D,Davenport P,Tipping P,Ronco C

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Extravascular lung water is a quantitative marker of the amount of fluid in the thoracic cavity besides the vasculature. Indexing to both predicted and actual body weight have been proposed to compare different individuals and provide a uniform range of normal. OBJECTIVE:We explored extravascular lung water...

journal_title：Critical care medicine

authors： Wolf S,Riess A,Landscheidt JF,Lumenta CB,Schürer L,Friederich P

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:To outline the concepts involved in optimizing antibacterial dosing in critically ill patients with acute renal failure undergoing continuous renal replacement therapy (CRRT), provide a strategy for optimizing dosing, and summarize the data required to implement the strategy. DATA SOURCES:MEDLINE search fro...

journal_title：Critical care medicine

authors： Choi G,Gomersall CD,Tian Q,Joynt GM,Freebairn R,Lipman J

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of two prognostic systems to predict hospital mortality in adult intensive care patients. DESIGN:Prospective cohort study. SETTING:A mixed medical and surgical intensive care unit (ICU) in the United Kingdom. PATIENTS:A total of 1,144 patients consecutively admitted to the study. I...

journal_title：Critical care medicine

authors： Beck DH,Taylor BL,Millar B,Smith GB

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Hypoxemic reperfusion attenuates brain injury secondary to severe cerebral ischemia, myocardial, and intestinal injury occurring in intestinal postischemic shock, and offers hemodynamic stabilization and attenuation of inflammatory response when applied in the resuscitation from hemorrhagic shock. In this stu...

journal_title：Critical care medicine

authors： Douzinas EE,Orfanos SE,Livaditi O,Augustatou K,Villiotou V,Kavantzas N,Flevari A,Korkolopoulou P,Roussos C,Patsouris E

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To examine the role of platelets, fibrin, and adhesion molecules in mediating neutrophil-endothelial cell interactions in septic shock. DESIGN:Controlled experiments using phase contrast microscopy to examine neutrophil, platelet, and endothelial cell interactions in flowing cell suspensions under simulated ...

journal_title：Critical care medicine

authors： Kirschenbaum LA,McKevitt D,Rullan M,Reisbeck B,Fujii T,Astiz ME

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:This pilot study was designed to identify which contextual factors facilitate/hinder the implementation of the awakening, breathing, coordination, delirium, and early mobility (ABCDE) bundle for guidance in future studies. DESIGN:The sources of data for this study included document review, planned site visit...

journal_title：Critical care medicine

authors： Carrothers KM,Barr J,Spurlock B,Ridgely MS,Damberg CL,Ely EW

更新日期：2013-09-01 00:00:00

abstract：:Hypophosphatemia may occur in Reye's syndrome. We retrospectively studied 42 patients with Reye's syndrome to determine the frequency and degree of hypophosphatemia, to identify possible causes, and to determine whether hypophosphatemia was related to the severity of disease or mortality. Nineteen (46%) patients were ...

journal_title：Critical care medicine

authors： Carroll JL,Kanter RK

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVES:To determine whether high rates of ineffective triggering within the first 24 hrs of mechanical ventilation (MV) are associated with longer MV duration and shorter ventilator-free survival (VFS). DESIGN:Prospective cohort study. SETTING:Medical intensive care unit (ICU) at an academic medical center. PATI...

journal_title：Critical care medicine

authors： de Wit M,Miller KB,Green DA,Ostman HE,Gennings C,Epstein SK

更新日期：2009-10-01 00:00:00

abstract：:Mucus plugging of a large airway resulted in the formation of a check-valve mechanism and pulmonary hyperinflation, rather than atelectasis. Fiberoptic bronchoscopy was both diagnostic and curative. The physician should be aware that mucus plugging may have unusual presentations and may mimic other clinical entities. ...

journal_title：Critical care medicine

authors： Rubin EM,Baier H

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVE:To determine how top loads with different doses of carbon monoxide (CO)-saturated saline solutions (CO-saline) affect microvascular and systemic hemodynamics and to delineate the corresponding biochemical mechanisms. DESIGN:Prospective study. SETTING:University research laboratory. SUBJECTS:Male Golden Syr...

journal_title：Critical care medicine

authors： Hangai-Hoger N,Tsai AG,Cabrales P,Suematsu M,Intaglietta M

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:The objectives of this article are to introduce and explore a novel paradigm based on complex nonlinear systems, and to evaluate its application to critical care research regarding the systemic host response and multiple organ dysfunction syndrome (MODS). DATA SOURCES:Published original work, review article...

journal_title：Critical care medicine

authors： Seely AJ,Christou NV

更新日期：2000-07-01 00:00:00

abstract：:The effects of PEEP and subsequent augmentation of cardiac output by sodium nitroprusside (SNP) were examined in a canine model of asymmetric oleic acid injury to the right lung. PEEP (9.2 +/- 0.5 cm H2O) was added to six animals to decrease venous admixture (Qsp/Qt) from 50.6 +/- 4.4% to 16.0 +/- 1.3% (p less than .0...

journal_title：Critical care medicine

authors： Johnston WE,Vinten-Johansen J,Tommasi E

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To investigate the mechanism by which methylprednisolone protects the liver from hypoxia-induced injury. DESIGN:Prospective control study using the isolated rat liver. SETTING:Animal research facility. SUBJECTS:Male, fasted, pathogen-free Sprague-Dawley rats. INTERVENTIONS:Low-flow hypoxia was produced by...

journal_title：Critical care medicine

authors： Motoyama S,Saito S,Minamiya Y,Saito R,Nakamura M,Okuyama M,Imano H,Ogawa J

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:The benefit of continuous on-site presence by a staff academic critical care specialist in the intensive care unit of a teaching hospital is not known. We compared the quality of care and patient/family and provider satisfaction before and after changing the staffing model from on-demand to continuous 24-hr c...

journal_title：Critical care medicine

authors： Gajic O,Afessa B,Hanson AC,Krpata T,Yilmaz M,Mohamed SF,Rabatin JT,Evenson LK,Aksamit TR,Peters SG,Hubmayr RD,Wylam ME

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Inflammation and immobility are comorbid etiological factors inducing muscle weakness in critically ill patients. This study establishes a rat model to examine the effect of inflammation and immobilization alone and in combination on muscle contraction, histology, and acetylcholine receptor regulation. DESIG...

journal_title：Critical care medicine

authors： Fink H,Helming M,Unterbuchner C,Lenz A,Neff F,Martyn JA,Blobner M

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:A recent post hoc analysis suggested that driving pressure may be more important than traditional ventilatory variables in determining outcome in mechanically ventilated patients with acute respiratory distress syndrome. We conducted a systematic review and meta-analysis to summarize the risk of mortality fo...

journal_title：Critical care medicine

authors： Aoyama H,Pettenuzzo T,Aoyama K,Pinto R,Englesakis M,Fan E

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:In rodent models, enhanced formation of nitric oxide and formation of peroxynitrite have been implicated in the pathogenesis of various forms of shock. Here we examined the effect of mercaptoethylguanidine (MEG), an inducible nitric oxide synthase inhibitor and peroxynitrite scavenger, in a severe hemorrhagic...

journal_title：Critical care medicine

authors： Szabó A,Hake P,Salzman AL,Szabó C

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:The renal effects of dopamine in critically ill patients remain controversial. Low-dose dobutamine has been reported to improve renal function. We compared the effects of various doses of dopamine and dobutamine on renal function in critically ill patients. DESIGN:Prospective, single-blind, randomized study....

journal_title：Critical care medicine

authors： Ichai C,Soubielle J,Carles M,Giunti C,Grimaud D

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:The clinical value of stroke volume variations to assess intravascular fluid status in critically ill patients is well known. Electrical impedance tomography is a noninvasive monitoring technology that has been primarily used to assess ventilation. We investigated the potential of electrical impedance tomogra...

journal_title：Critical care medicine

authors： Maisch S,Bohm SH,Solà J,Goepfert MS,Kubitz JC,Richter HP,Ridder J,Goetz AE,Reuter DA

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To measure the impact of staged implementation of full versus partial ABCDE bundle on mechanical ventilation duration, ICU and hospital lengths of stay, and cost. DESIGN:Prospective cohort study. SETTING:Two medical ICUs within Montefiore Healthcare Center (Bronx, NY). PATIENTS:One thousand eight hundred ...

journal_title：Critical care medicine

authors： Hsieh SJ,Otusanya O,Gershengorn HB,Hope AA,Dayton C,Levi D,Garcia M,Prince D,Mills M,Fein D,Colman S,Gong MN

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To assess whether the provision of computerized physiologic trend data could improve outcome in newborn infants requiring intensive care. DESIGN:Randomized, controlled trial, with subsidiary questionnaire studies. SETTING:Tertiary neonatal intensive care unit with 12 intensive care cots. PATIENTS:All infan...

journal_title：Critical care medicine

authors： Cunningham S,Deere S,Symon A,Elton RA,McIntosh N

更新日期：1998-12-01 00:00:00

abstract：:Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular fibrin formation occurring in the course of a variety of severe diseases. In gram-negative sepsis, endotoxin is the bacterial component eliciting a cascade of tissue factor dependent hypercoagulable reactions mediated b...

journal_title：Critical care medicine

authors： ten Cate H

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Our intent was to evolve a prognosticator that would predict the likelihood that an electrical shock would restore a perfusing rhythm. Such a prognosticator was to be based on conventional electrocardiographic signals but without constraints caused by artifacts resulting from precordial compression. The adver...

journal_title：Critical care medicine

authors： Marn-Pernat A,Weil MH,Tang W,Pernat A,Bisera J

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To provide an overview of key elements of the Affordable Care Act. To evaluate ways in which the Affordable Care Act will likely impact the practice of critical care medicine. To describe strategies that may help health systems and providers effectively adapt to changes brought about by the Affordable Care A...

journal_title：Critical care medicine

authors： Dogra AP,Dorman T

更新日期：2016-03-01 00:00:00