Abstract：
:The 15-methyl analog of prostaglandin F2 alpha (15-ME-PGF2 alpha), administered in a 3-mg dose via a single vaginal suppository and supplemented at 24 hours by intramuscular injection(s) of 250 micrograms, successfully induced abortion in 80 of 81 patients in the midtrimester of pregnancy. The mean abortion time was 19.6 hours. Two thirds of the patients aborted after treatment with the suppository alone in a mean time of 14.6 hours; the remaining 27 patients required intramuscular injections of 15-ME-PGF2 alpha to effect expulsion of the products of conception. Twenty-six of these 27 patients subsequently aborted in a mean total abortion time of 29.6 hours. Fifty-eight patients aborted within 24 hours of the initial prostaglandin administration, and 78 aborted by 36 hours. Parity and length of gestation did not significantly affect abortion time in this series, although the mean abortion time for parous patients and patients with gestations earlier than 17 weeks tended to be somewhat shorter than that of nulliparous patients and those with more advanced gestations. The placenta was spontaneously expelled in the majority of patients. Abortion was incomplete in 3 patients and required curettage. Uterine activity, as measured via an intraamniotic catheter in 6 patients, developed very gradually with the suppository, peaking at 3 hours after insertion, and was characterized by regular contractions with low intrauterine baseline tonus. The gastrointestinal side effects that occurred in 59% of patients who received the suppository were also most frequently observed at 3 hours after administration. In contrast the gastrointestinal disturbances elicited by intramuscular injections of the analog immediately followed the administration.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Lauersen NH,Den T,Scher J,Iliescu C,Wilson KHsubject
Has Abstractpub_date
1981-07-01 00:00:00pages
96-100issue
1eissn
0029-7844issn
1873-233Xjournal_volume
58pub_type
杂志文章abstract：BACKGROUND:Pelvic vein thrombosis may occur in nonpuerperal patients with hypercoagulable conditions and have significant sequelae. The purpose of this report is to describe a nonpuerperal woman with factor V Leiden mutation who developed acute pelvic pain secondary to pelvic varix thrombosis. CASE:A multiparous woman...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(01)01589-7
更新日期：2002-05-01 00:00:00
abstract：OBJECTIVE:To determine how pregnant women of varying ages, races, ethnicities, and socioeconomic backgrounds value procedure-related miscarriage and Down-syndrome-affected birth. METHODS:We studied cross-sectionally 534 sociodemographically diverse pregnant women who sought care at obstetric clinics and practices thro...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)00969-8
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:Amyloidosis of the endometrium is a rare occurrence according to current literature. Previously reported cases have presented with menorrhagia or postmenopausal bleeding. CASE:A postmenopausal woman with multiple medical problems presented with fatigue and weight loss. During the evaluation for her 18-kg we...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000124985.48138.7e
更新日期：2004-11-01 00:00:00
abstract：:An unusual case is presented of advanced dysgerminoma in a patient with Swyer syndrome, 46,XY pure gonadal dysgenesis. Unexpected regional invasion necessitated bowel resection, total abdominal hysterectomy, and bilateral salpingogonadectomy for a complete en bloc excision of the primary tumor mass and the dysgenetic ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the transplacental passage of vancomycin in term, uninfected pregnant women. METHODS:A single vancomycin 1-g dose was administered intravenously at four separate time intervals to 13 uncomplicated nonlaboring women undergoing scheduled cesarean delivery. Samples of maternal blood and fetal cord b...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000260388.78339.b6
更新日期：2007-05-01 00:00:00
abstract：:Three patients with International Federation of Gynecology and Obstetrics state IIIC ovarian adenocarcinoma underwent CO2 laser vaporization of large-volume (5-6 cm) and miliary right hemidiaphragmatic metastases at the conclusion of standard debulking surgery to effect optimal cytoreduction. Destruction of diaphragma...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:The techniques and applications of amniocentesis performed with a new high-frequency aspiration-biopsy transducer are described in detail. The advantages of this technique are greatest in third-trimester patients where active fetal motion and diminished amniotic fluid volumes make unguided punctures difficult or impos...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：:Hydramnios and maternal renal compromise are described in a singleton pregnancy with a large fetal abdominal cystic mass. Both the hydramnios and the renal failure resolved after percutaneous drainage of the fetal cyst. Rapid reaccumulation of the mass resulted in redrainage and placement of an indwelling cyst/amnioti...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198409001-00007
更新日期：1984-09-01 00:00:00
abstract：:Although the passage early in labor of thick amniotic fluid heavily stained with meconium is recognized as an indication of potential fetal asphyxia, the significance of late passage of meconium-stained fluid in labor is less certain. One hundren twenty-eight patients with late passage of meconium in labor and 134 con...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
abstract：:In experiments performed in anesthetized monkeys in the third trimester of pregnancy, mean maternal arterial blood pressure was continuously monitored, the uterine artery blood flow was measured with an electromagnetic flow probe, and prostaglandin levels were assayed in the uterine venous effluent. After inhibition o...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1977-11-01 00:00:00
abstract：:The effect of maternal age on the incidence and significance of hydatidiform mole in 2202 patients studied at the Southeastern Regional Trophoblastic Disease Center during 1978 to 1982 is analyzed. Results are compared with a contemporary control group that comprised all types of pregnancy events. A significant increa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the usefulness and cost-effectiveness of the routine preoperative evaluation of blood type and screen testing before laparoscopy. METHODS:A retrospective review was conducted in patients transfused with blood during or after laparoscopy over a 3-year period at Hutzel Hospital, Detroit, Michigan; ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/0029-7844(95)00187-V
更新日期：1995-09-01 00:00:00
abstract：:Laparoscopy was used to evaluate 100 women who consistently reported pelvic pain in the same location for a minimum of six months. These findings were compared with those of 50 asymptomatic women who underwent laparoscopy for tubal ligation. Overall, 83% of the group with pelvic pain had abnormal pelvic organs as comp...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：:Topical 5-fluorouracil (5-FU) has proven effective in epidermoid cancers of the head and neck. Its effectiveness has been correlated with the ability of the patient's immunologic system to recognize new antigens. In this study, 8 patients with carcinoma in situ of the vulva were evaluated and treated with topical 5-FU...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To develop a simulation-based curricular unit for labor and delivery teams involved in obstetric emergencies to detect and address common mistakes. METHODS:A simulation-based curricular unit for hands-on training of four obstetric emergency scenarios was developed using high-tech mannequins and low-tech simu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000265208.16659.c9
更新日期：2007-06-01 00:00:00
abstract：:Uterine leiomyomas are associated with various complications during pregnancy. During a 2-year period, pregnant women with a history of leiomyomas were referred to our antenatal testing unit for ultrasound evaluation. Eighty-five patients were found to have single or multiple leiomyomas by ultrasound examination. The ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Four white women who developed osteosarcoma during pregnancy were referred for treatment, 2 prior to delivery and development of metastases, and 2 after delivery and development of metastases. After amputation, these patients received combination chemotherapy with either vincristine-cyclophosphamide or adriamycin-cycl...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
abstract：OBJECTIVES:Use of prostaglandins, including sulprostone (an E2 analog), is recommended for second-line uterotonic treatment of atonic postpartum hemorrhage and might be considered as an indicator of quality of care in severe atonic postpartum hemorrhage management. Our objective was to estimate whether sulprostone was ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1097/AOG.0b013e3182255335
更新日期：2011-08-01 00:00:00
abstract：:Cytologic diagnosis of adenocarcinoma metastatic to the peritoneal surface is often hampered by the difficulty of differentiating between reactive mesothelial cells and macrophages from malignant epithelial cells by light microscopy. With in vitro tissue culture technics, the fibroblastic dedifferentiation of mesothel...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-197507000-00015
更新日期：1975-07-01 00:00:00
abstract：:One hundred fifty-two women who received cefazolin prophylaxis and subsequently developed postpartum endometritis were randomized to treatment with either ticarcillin/clavulanic acid (75) or clindamycin-gentamicin (77). Bacteria isolated from the endometrium were predominantly facultative anaerobic bacteria. The ratio...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVE:To compare tubal anastomosis by robotic system compared with outpatient minilaparotomy. METHODS:In this retrospective case-control study, women were identified by current procedural terminology code for tubal anastomosis. We included all cases of tubal anastomosis for reversal of a prior tubal ligation by ei...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000264591.43544.0f
更新日期：2007-06-01 00:00:00
abstract：:Phenylketonuria (PKU) is an autosomal recessive disorder of phenylalanine (Phe) metabolism characterized by a deficiency of the hepatic enzyme, phenylalanine hydroxylase, an enzyme responsible for the conversion of phenylalanine to tyrosine, and elevated levels of Phe and Phe metabolite. All women with PKU or hyperphe...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3181c6f93d
更新日期：2009-12-01 00:00:00
abstract：:An in-depth analysis of numbers of obstetric and gynecologic operations from 1979 to 1984 was performed using data from the National Center for Health Statistics. During the study period, there was a decrease in total numbers of obstetric and gynecologic procedures of 1%. During the same five-year period the numbers o...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198606000-00001
更新日期：1986-06-01 00:00:00
abstract：:Premature rupture of the membranes is a common and serious complication of pregnancy. Despite the prevalence and severity of sequelae, current diagnostic techniques are less than ideal. We studied 48 women with preterm rupture of the membranes with a rapid, colorimetric monoclonal alpha-fetoprotein (AFP) antibody test...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：OBJECTIVE:To assess the relationship between preeclampsia or eclampsia and stroke, myocardial infarction (MI), subsequent cardiovascular outcomes, and long-term survival. METHODS:Using the Myocardial Infarction Data Acquisition System in New Jersey (1994-2009), we analyzed cardiovascular outcomes in women with and wit...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31826ae78a
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to estimate the probability of spontaneous delivery at 34 weeks or less according to cervical assessment by transvaginal scan associated with previous obstetric history. METHODS:Ultrasound transvaginal cervical length and presence of funneling were evaluated in 1,958 singleton pregn...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000154157.22500.1d
更新日期：2005-03-01 00:00:00
abstract：:Short-term oral steroid therapy was used to treat a capillary hemangioma of the vagina and urethra in a young child. After 8 weeks of prednisolone therapy (40 mg every other day decreasing to 2.5 mg every other day), vaginal bleeding has not recurred. At 2 years and 8 months, the patient presented with severe hematuri...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1989-05-01 00:00:00
abstract：:Fifty-two women undergoing labor induction and vaginal delivery at term were randomized between two oxytocin infusion protocols, involving hourly versus quarter-hourly increases in dose. Potential differences were sought of duration of labor, amount of uterine activity generated, and amount of oxytocin required. Start...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-05-01 00:00:00
abstract：:This study reports serum levels of relaxin in normal and special-interest pregnancies using an homologous radioimmunoassay for human relaxin. The mean levels in uncomplicated antenatal patients were lower than those reported in studies using heterologous assays, but the trend in serum levels was similar. Serum levels ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:Several authorities have recommended cesarean section for all intrapartum breech presentations. The present study documents that judiciously selected fetuses at term in breech presentation may be safely delivered vaginally by a selective management protocol that requires cesarean section when mandated criteria are not...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
