"Living cytology" in the diagnosis of intraabdominal adenocarcinoma.

Abstract:

:Cytologic diagnosis of adenocarcinoma metastatic to the peritoneal surface is often hampered by the difficulty of differentiating between reactive mesothelial cells and macrophages from malignant epithelial cells by light microscopy. With in vitro tissue culture technics, the fibroblastic dedifferentiation of mesothelial cells facilitates the recognition of residual neoplastic epithelial cells. Ascitic fliid from 18 patients who ultimately had histologic documentation of intraabdominal adenocarcinomatosis was studied by tissue culture technics. In 15 of the 18 patients, small islets of replicating tumor cells could be identified after the mesothelial cells had dedifferentiated into fibroblasts. With one exception the average time between collection of the specimen and recognition of adenocarcinoma was 6 days. In 14 cases, a definitive diagnosis of malignancy was made by cytologic analysis.

journal_name

Obstet Gynecol

authors

Monif GR,Daly JW

doi

10.1097/00006250-197507000-00015

subject

Has Abstract

pub_date

1975-07-01 00:00:00

pages

80-3

issue

1

eissn

0029-7844

issn

1873-233X

journal_volume

46

pub_type

杂志文章
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    authors: Mora S,Weber G,Guarneri MP,Nizzoli G,Pasolini D,Chiumello G

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  • Mucinous carcinoma of the endometrium.

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  • Transabdominal cerclage: a laparoscopic approach.

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    authors: Bachmann GA,Trattler B,Ko T,Tweddel G

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    更新日期:1992-09-01 00:00:00

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    pub_type: 杂志文章,多中心研究

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    更新日期:1987-02-01 00:00:00

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