ACOG Committee Opinion No. 449: Maternal phenylketonuria.


:Phenylketonuria (PKU) is an autosomal recessive disorder of phenylalanine (Phe) metabolism characterized by a deficiency of the hepatic enzyme, phenylalanine hydroxylase, an enzyme responsible for the conversion of phenylalanine to tyrosine, and elevated levels of Phe and Phe metabolite. All women with PKU or hyperphenylalaninemia should be strongly encouraged to receive family planning and preconception counseling. Women with PKU or hyperphenylalaninemia should begin appropriate, medically directed dietary phenylalanine restriction before conception.


Obstet Gynecol





Has Abstract


2009-12-01 00:00:00














  • Advanced abdominal pregnancy resulting from late uterine rupture.

    abstract:BACKGROUND:Advanced abdominal pregnancy is rare, and one that occurs after uterine rupture with delivery of a viable fetus is exceptional. CASE:A multiparous patient was admitted at 29 weeks of gestation for conservative management of placenta previa. She complained of intermittent abdominal pain, but repeated assessm...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Naim NM,Ahmad S,Siraj HH,Ng P,Mahdy ZA,Razi ZR

    更新日期:2008-02-01 00:00:00

  • Threatened abortion studied by estradiol-17 beta in serum and ultrasound.

    abstract::One hundred women were admitted to the hospital between 7 and 18 weeks' gestation because of vaginal bleeding and threatened abortion. Serum concentration of estradiol-17 beta was determined by radioimmunoassay. Ultrasound examination using a gray-scale scanner was performed as well. The values for prediction of abort...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Hertz JB,Mantoni M,Svenstrup B

    更新日期:1980-03-01 00:00:00

  • Does standing up improve the predictive value of the supine pressor test for gestational hypertension?

    abstract::Fifty-six primigravid women at 28-32 weeks' gestation were studied prospectively to compare the roll-over test with the stand-up pressor test in the prediction of gestational hypertension. Blood pressures were measured in the different positions continuously using an automated machine. Twenty patients developed gestat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Okonofua FE,Onwudiegwu U,Odunsi AO,Hussain S,O'Brien PM

    更新日期:1990-09-01 00:00:00

  • Return of ovulation and menses in postpartum nonlactating women: a systematic review.

    abstract:OBJECTIVES:To estimate, from the literature, when nonlactating postpartum women regain fertility. DATA SOURCES:We searched PubMed and Cochrane Library databases for all articles (in all languages) published in peer-reviewed journals from database inception through May 2010 for evidence related to the return of ovulati...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Jackson E,Glasier A

    更新日期:2011-03-01 00:00:00

  • Association of Pharmacist Prescription of Hormonal Contraception With Unintended Pregnancies and Medicaid Costs.

    abstract:OBJECTIVE:To estimate unintended pregnancies averted and the cost effectiveness of pharmacist prescription of hormonal contraception. METHODS:A decision-analytic model was developed to determine the cost effectiveness of expanding the scope of pharmacists to prescribe hormonal contraception compared with the standard ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Rodriguez MI,Hersh A,Anderson LB,Hartung DM,Edelman AB

    更新日期:2019-06-01 00:00:00

  • Calcium supplementation in mild preeclampsia remote from term: a randomized double-blind clinical trial.

    abstract:OBJECTIVE:To determine whether calcium supplementation prevents progression to severe disease in preterm nulliparous women with mild preeclampsia. METHODS:Seventy-five women hospitalized at 24-36 weeks' gestation because of mild preeclampsia were randomized to receive either 2 g/day of elemental calcium (36 women) or ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Sanchez-Ramos L,Adair CD,Kaunitz AM,Briones DK,Del Valle GO,Delke I

    更新日期:1995-06-01 00:00:00

  • Detection of benign endometrial masses by endometrial stripe measurement in premenopausal women.

    abstract:OBJECTIVE:Our objective was to estimate whether a transvaginal endometrial stripe of less than 5 mm in premenopausal women would exclude endometrial polyps and intracavitary leiomyomata, thereby eliminating the need for sonohysterography. METHODS:Data from 206 consecutive sonohysterograms performed in premenopausal wo...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Breitkopf DM,Frederickson RA,Snyder RR

    更新日期:2004-07-01 00:00:00

  • Intravenous leiomyomatosis with cardiac extension: successful surgical management and histopathologic study.

    abstract::A case of intravenous leiomyomatosis with cardiac extension was treated successfully with a two-stage operation: resection of the intracardiac and intracaval mass for the first stage and total hysterectomy with bilateral salpingo-oophorectomy for the second. Tumors were located either within or in continuity to dilate...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Suginami H,Kaura R,Ochi H,Matsuura S

    更新日期:1990-09-01 00:00:00

  • Committee Opinion No. 646: Ethical Considerations for Including Women as Research Participants.

    abstract::Inclusion of women in research studies is necessary for valid inferences about health and disease in women. The generalization of results from trials conducted in men may yield erroneous conclusions that fail to account for the biologic differences between men and women. Although significant changes in research design...

    journal_title:Obstetrics and gynecology

    pub_type: 共识发展会议,杂志文章



    更新日期:2016-05-01 00:00:00

  • Primary Dysmenorrhea: Diagnosis and Therapy.

    abstract::Primary dysmenorrhea is defined as pain during the menstrual cycle in the absence of an identifiable cause. It is one of the most common causes of pelvic pain in women. Dysmenorrhea can negatively affect a woman's quality of life and interfere with daily activities. The pathophysiology of primary dysmenorrhea is likel...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Ferries-Rowe E,Corey E,Archer JS

    更新日期:2020-11-01 00:00:00

  • Ulipristal Acetate for Treatment of Uterine Leiomyomas: A Randomized Controlled Trial.

    abstract:OBJECTIVE:To assess the efficacy and tolerability of ulipristal acetate, a selective progesterone receptor modulator, for treatment of symptomatic uterine leiomyomas. METHODS:This phase 3, double-blind, double-dummy, placebo-controlled trial randomized premenopausal women (18-50 years) with uterine leiomyomas and abno...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Liu JH,Soper D,Lukes A,Gee P,Kimble T,Kroll R,Mallick M,Chan A,Gillard P,Harrington A,Sniukiene V,Shulman LP

    更新日期:2018-11-01 00:00:00

  • Neonatal performance of the selected term vaginal breech delivery.

    abstract::Several authorities have recommended cesarean section for all intrapartum breech presentations. The present study documents that judiciously selected fetuses at term in breech presentation may be safely delivered vaginally by a selective management protocol that requires cesarean section when mandated criteria are not...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Gimovsky ML,Petrie RH,Todd WD

    更新日期:1980-12-01 00:00:00

  • Second Uterine Curettage and the Number of Chemotherapy Courses in Postmolar Gestational Trophoblastic Neoplasia: A Randomized Controlled Trial.

    abstract:OBJECTIVE:To investigate the effect of second uterine curettage on the number of chemotherapy courses and relapse rate in low-risk postmolar gestational trophoblastic neoplasia. METHODS:In a phase III trial, patients with low risk gestational trophoblastic neoplasia were randomised (1:1) to a second curettage or no cu...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验


    authors: Hemida R,Vos EL,El-Deek B,Arafa M,Toson E,Burger CW,van Doorn HC

    更新日期:2019-05-01 00:00:00

  • Clinical significance of urethral instability.

    abstract::Variations of urethral pressure were registered with microtransducers in 427 gynecologic patients with lower urinary tract symptoms during urethrocystometry. Urethral instability (variation of urethral pressure greater than 15 cm of water) was found in 16.4% of patients. The comparison of the urinary symptoms and the ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Weil A,Miège B,Rottenberg R,Krauer F

    更新日期:1986-07-01 00:00:00

  • Endocervical curettage when colposcopic examination is satisfactory and normal.

    abstract:OBJECTIVE:To estimate the incidence of endocervical dysplasia in women with cervical cytology of atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (SIL) who have a satisfactory and normal colposcopic examination. METHODS:An electronic colposcopy database was revi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Williams DL,Dietrich C,McBroom J

    更新日期:2000-06-01 00:00:00

  • Amniotic fluid index and single deepest pocket: weak indicators of abnormal amniotic volumes.

    abstract:OBJECTIVE:To compare amniotic fluid index (AFI) with the single deepest pocket in the identification of actual abnormal amniotic fluid (AF) volumes. METHODS:One hundred seventy-nine women with singleton pregnancies at the University of Mississippi between March 1994 and June 1999 had ultrasound estimations of AF volum...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Magann EF,Chauhan SP,Barrilleaux PS,Whitworth NS,Martin JN

    更新日期:2000-11-01 00:00:00

  • Localization of 3H-estradiol-17beta in diethylstilbestrol-induced adenosis.

    abstract::Treatment of neonatal mice with diethylstilbestrol results in the appearance of adenosis in the uterine cervix and upper part of the vagina in later life. Using dry mount autoradiography, the uptake and distribution of [3H]-estradiol in the same regions were studied after in vivo injections with [3H]-estradiol. It was...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Kalland T,Fossberg TM,Forsberg JG

    更新日期:1978-04-01 00:00:00

  • Elevated maternal serum alpha-fetoprotein with oligohydramnios: ultrasound evaluation and outcome.

    abstract::Nineteen pregnancies evaluated for elevated maternal serum alpha-fetoprotein levels were found to have moderate to severe oligohydramnios. There were no survivors among six fetuses with ultrasound-diagnosed urinary tract anomalies. We followed 11 of the remaining 13 pregnancies with serial ultrasound examinations. Whe...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Richards DS,Seeds JW,Katz VL,Lingley LH,Albright SG,Cefalo RC

    更新日期:1988-09-01 00:00:00

  • Intrauterine growth retarded infants. Correlation of gestational age with maternal factors, mode of delivery, and perinatal survival.

    abstract::Fifty-eight infants of 3332 deliveries (1.7%) were found to be growth retarded (IGR) at birth. For purposes of analysis, the infants were divided into 2 groups according to gestational age at delivery: Group I infants were delivered between 38 and 43 weeks' gestation, and Group II infants were delivered between 28 and...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Perry CP,Harris RE,DeLemos RA,Null DM Jr

    更新日期:1976-08-01 00:00:00

  • An evaluation of the significance of positive oxytocin challenge test.

    abstract::Sixty-six of 390 patients studied at LAC/USC Women's Hospital between 1970 and 1973 had positive oxytocin challenge tests (OCT). Twenty-four percent of patients who were allowed direct monitored labor after a positive OCT showed no late deceleration and must be assumed to have had false-positive tests. Patients with p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Freeman RK,Goebelsman UW,Nochimson D,Cetrulo C

    更新日期:1976-01-01 00:00:00

  • Changes in amniotic fluid prostaglandins with oxytocin-induced labor.

    abstract::Amniotic fluid prostaglandin levels were measured serially in 15 patients who underwent successful induction of labor and compared with those of patients presenting in spontaneous labor. At comparable cervical dilation the induced group demonstrated significantly lower prostaglandin levels. Four of these patients deli...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Padayachi T,Norman RJ,Reddi K,Shweni PM,Philpott RH,Joubert SM

    更新日期:1986-11-01 00:00:00

  • Decreased plasma tryptophan in pregnancy.

    abstract:OBJECTIVE:To examine levels of serum tryptophan and its degradation product kynurenine in uncomplicated pregnancy, according to the week of pregnancy and the concentrations of neopterin. METHODS:Plasma was analyzed from 45 healthy pregnant women (15 in each trimester), 15 healthy puerperas, and 20 nonpregnant controls...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Schröcksnadel H,Baier-Bitterlich G,Dapunt O,Wachter H,Fuchs D

    更新日期:1996-07-01 00:00:00

  • Rapid B-scan (real-time) ultrasonography in the identification and evaluation of twin pregnancies.

    abstract::Real-time ultrasonography utilizing a hand-held linear array transducer provides a highly accurate method of identifying and evaluating the twin gestation. The rapidity of real-time scanning eliminates interpretational problems caused by fetal movements. Additionally, the versatility of transducer positioning facilita...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Levine SC,Filly RA

    更新日期:1978-02-01 00:00:00

  • Gestational age-dependent reference values for pH in umbilical cord arterial blood at term.

    abstract:OBJECTIVE:Despite a change of fetal physiologic and biochemical functions with gestational age, stationary umbilical cord acid-base reference values are used as measures of obstetric care quality. The aim of this study was to assess the risk of low Apgar score relative to low pH when using stationary versus gestational...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Kitlinski ML,Källén K,Marsál K,Olofsson P

    更新日期:2003-08-01 00:00:00

  • Amniotic fluid alpha-fetoprotein as a marker in prenatal diagnosis of neural tube defects.

    abstract::The prenatal diagnosis of anencephaly and spina bifida (neural tube defect, NTD) through amniotic fluid analysis for alpha-fetoprotein (AFP) is gradually gaining clinical recognition. AFP concentrations were determined in 237 amniotic fluids from normal pregnancies ranging between 7 and 42 weeks of gestation. A steady...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Weiss RR,Macri JN,Elligers K,Princler GL,McIntire R,Waldman TA

    更新日期:1976-02-01 00:00:00

  • Real-time sonography in obstetrics.

    abstract::Three hundred fifty real-time scans were performed on pregnant women for various indications. Placental localization was satisfactorily obtained in 173 of 174 studies. Estimates of fetal gestation from directly measured biparietal diameter were +/-2 weeks of actual gestation in 153 of 172 (88.9%) measurements. The pre...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Anderson SG

    更新日期:1978-03-01 00:00:00

  • Laser therapy of genital condylomata acuminata.

    abstract::The effectiveness of the carbon dioxide laser was evaluated in the treatment of penile, anorectal, and urethral condylomata acuminata in 40 men. All but six cases of urethral condylomata were prior conventional treatment failures. Postlaser follow-up ranged between one and two years, with an average of 16 months. No p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Ferenczy A

    更新日期:1984-05-01 00:00:00

  • Evaluation of Smartphone Menstrual Cycle Tracking Applications Using an Adapted APPLICATIONS Scoring System.

    abstract:OBJECTIVE:To identify smartphone menstrual cycle tracking applications (apps) and evaluate their accuracy, features, and functionality. METHODS:In this systematic evaluation, we searched the Apple iTunes store for free menstrual cycle tracking apps for patient use. We considered an application accurate if menstrual cy...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Moglia ML,Nguyen HV,Chyjek K,Chen KT,Castaño PM

    更新日期:2016-06-01 00:00:00

  • Uterine necrosis after arterial embolization for postpartum hemorrhage.

    abstract:BACKGROUND:Selective embolization is an effective and reputedly safe method of managing pregnancy-related bleeding. However, we report an ischemic uterine necrosis after arterial embolization. CASE:The patient had heavy postpartum bleeding treated by embolization of the uterine arteries using polyvinyl alcohol particl...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Cottier JP,Fignon A,Tranquart F,Herbreteau D

    更新日期:2002-11-01 00:00:00

  • Umbilical artery regression: a rare complication of intravascular fetal transfusion.

    abstract:BACKGROUND:Intravascular fetal transfusion is an important therapeutic advance but is associated with several complications. Regression of an umbilical artery associated with transfusion is rare. CASE:A case of red blood cell alloimmunization managed by serial transfusions was complicated by functional loss of an umbi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Smith JF Jr,Warner KD,Bergmann M,Pushchak MJ

    更新日期:1999-05-01 00:00:00