Relaxin in human pregnancy serum measured with an homologous radioimmunoassay.

Abstract:

:This study reports serum levels of relaxin in normal and special-interest pregnancies using an homologous radioimmunoassay for human relaxin. The mean levels in uncomplicated antenatal patients were lower than those reported in studies using heterologous assays, but the trend in serum levels was similar. Serum levels peaked at ten weeks' gestation and decreased progressively to term. Relaxin was detectable in all pregnant subjects assessed at the time of the first missed menses. The mean relaxin levels in patients having in vitro fertilization and embryo transfer who subsequently delivered a single infant were significantly higher than those in normal antenatal patients at an equivalent gestational age. Patients with twin pregnancies after in vitro fertilization and embryo transfer generally had higher levels than patients with single pregnancies. Some pregnant patients who aborted after in vitro fertilization and embryo transfer had declining levels of relaxin before 40 days postlaparoscopy.

journal_name

Obstet Gynecol

authors

Bell RJ,Eddie LW,Lester AR,Wood EC,Johnston PD,Niall HD

subject

Has Abstract

pub_date

1987-04-01 00:00:00

pages

585-9

issue

4

eissn

0029-7844

issn

1873-233X

journal_volume

69

pub_type

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