A rapid modification of the beta-hCG radioimmunoassay. Use as an aid in the diagnosis of ectopic pregnancy.

Abstract:

:Over half the patients with proven ectopic pregnancies have negative urinary slide or tube pregnancy tests at the time they present with symptoms. Because of the morbidity and mortality associated with unrecognized ectopic pregnancy, the need for an accurate, rapid, sensitive, and specific method for measuring low levels of human chorionic gonadotropin (hCG) is apparent. A three-hour radioimmunoassay (RIA) for serum hCG with a sensitivity of 5 mlU/ml was developed which utilizes an antiserum generated against the beta subunit of hCG, 125I-hCG for tracer purposes, a highly purified hCG standard, and dioxane for separation of bound from free hormone. Blood samples were obtained from 52 patients with suspected ectopic pregnancies. Twenty-four of these patients had a surgically proven ectopic gestation. The blood samples were analyzed in the above described RIA, and in the standard (24-hour) double antibody beta-hCG RIA. There were no false positive or false negative results by either assay. These results indicate that the dioxane modification of the beta-hCG RIA is an accurate and rapid method for confirming the diagnosis of ectopic pregnancy.

journal_name

Obstet Gynecol

authors

Rasor JL,Braunstein GD

subject

Has Abstract

pub_date

1977-11-01 00:00:00

pages

553-8

issue

5

eissn

0029-7844

issn

1873-233X

journal_volume

50

pub_type

杂志文章
  • Bias in the Peer Review Process: Can We Do Better?

    abstract::Peer review is the major method used by the scientific community to evaluate manuscripts and decide what is suitable for publication. However, this process in its current design is not bulletproof and is prone to reviewer and editorial bias. Its lack of objectivity and transparency raise concerns that manuscripts migh...

    journal_title:Obstetrics and gynecology

    pub_type: 社论

    doi:10.1097/AOG.0000000000003260

    authors: Tvina A,Spellecy R,Palatnik A

    更新日期:2019-06-01 00:00:00

  • Correlation of uterine activity using the Term Guard monitor versus standard external tocodynamometry compared with the intrauterine pressure catheter.

    abstract::Uterine activity monitoring to detect preterm contractions and thus to manage patients in active labor is valuable to the clinician. Uterine activity measured by external devices using the guard ring principle or by standard tocodynamometers has been shown to be accurate concerning the frequency of uterine activity as...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Hess LW,McCaul JF,Perry KG,Howard PR,Morrison JC

    更新日期:1990-07-01 00:00:00

  • Intrauterine aspiration of a large fetal ovarian cyst.

    abstract::Most large series of neonatal ovarian cysts are limited to those diagnosed in the newborn period. Eight cases of fetal ovarian cysts diagnosed prenatally by ultrasound have been reported, only one of which was aspirated in utero. Reported is the youngest fetus to undergo in utero aspiration of an ovarian cyst to reduc...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Landrum B,Ogburn PL Jr,Feinberg S,Bendel R,Ferrara B,Johnson DE,Thompson TR

    更新日期:1986-09-01 00:00:00

  • Persistent ectopic pregnancy following laparoscopic linear salpingostomy.

    abstract::As the surgical approach for ectopic pregnancies evolves from radical to conservative procedures, the potential hazard of persistent ectopic pregnancy has become increasingly pertinent. From September 1, 1986 to August 31, 1989, 11 women with persistent ectopic pregnancy after laparoscopic salpingostomy were diagnosed...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Seifer DB,Gutmann JN,Doyle MB,Jones EE,Diamond MP,DeCherney AH

    更新日期:1990-12-01 00:00:00

  • Oral contraceptives and nonfatal vascular disease.

    abstract::A follow-up study of more than 65,000 healthy women aged 15 to 44 was conducted to assess the association between oral contraceptive use and thromboembolism, stroke, or nonfatal myocardial infarction from 1980 through 1982 at Group Health Cooperative of Puget Sound. A positive association existed between current oral ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Porter JB,Hunter JR,Jick H,Stergachis A

    更新日期:1985-07-01 00:00:00

  • Diminished bilirubin binding by the serum of pregnant women.

    abstract::Enzymatic peroxidase oxidation was used to study albumin-bilirubin binding in the serum of pregnant women, their term infants, and nonpregnant women. When the bilirubin titration curves were corrected for differing albumin concentrations in the three groups, the bilirubin binding of pregnant women was inferior to that...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ritter DA,Gabai BR,Kenny JD

    更新日期:1985-05-01 00:00:00

  • Implementing Couple's Human Immunodeficiency Virus Testing and Counseling in the Antenatal Care Setting.

    abstract:OBJECTIVE:To describe a pilot implementation of couple's human immunodeficiency virus (HIV) testing and counseling in an antenatal care clinic in the United States. METHODS:We used a cross-sectional study design. Couples were recruited from an antenatal care clinic of a large, urban, tertiary medical center, and were ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003932

    authors: Momplaisir F,Finley E,Wolf S,Aaron E,Inoyo I,Bennett D,Seyedroudbari S,Groves A

    更新日期:2020-09-01 00:00:00

  • Maximal exercise testing in late gestation: fetal responses.

    abstract:OBJECTIVE:To determine the fetal response to and safety of maximal maternal exercise in the third trimester. METHODS:Twenty-three active women with uncomplicated pregnancies (singleton gestations) underwent maximal exercise testing in late gestation using a progressive maximal cycle ergometer protocol. Fetal heart rat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)00940-6

    authors: MacPhail A,Davies GA,Victory R,Wolfe LA

    更新日期:2000-10-01 00:00:00

  • Fetal stroke associated with elevated maternal anticardiolipin antibodies.

    abstract::Middle cerebral artery infarction explains some cases of congenital hemiparesis with or without neonatal stroke. The etiology of the stroke is often obscure. We describe two infants with imaging evidence of middle cerebral artery infarction whose mothers had elevated anticardiolipin antibody levels after delivery. We ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Silver RK,MacGregor SN,Pasternak JF,Neely SE

    更新日期:1992-09-01 00:00:00

  • Preinduction cervical ripening with prostaglandin E2 intracervical gel.

    abstract::A double-blind, placebo-controlled, dose-ranging study was undertaken to evaluate the efficacy of two doses of intracervical prostaglandin E2 gel in patients with unfavorable Bishop scores. Mean change in Bishop score, success of softening, time to labor, and time to delivery were all significantly different in the tw...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Laube DW,Zlatnik FJ,Pitkin RM

    更新日期:1986-07-01 00:00:00

  • Twice a cesarean, always a cesarean?

    abstract::The cesarean delivery rate has quadrupled during the past two decades, resulting in considerable attention focused on alternatives to cesarean birth. One option, vaginal birth after one previous cesarean, has come to be recognized as an acceptable alternative to routine elective repeat cesarean delivery. The purpose o...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Phelan JP,Ahn MO,Diaz F,Brar HS,Rodriguez MH

    更新日期:1989-02-01 00:00:00

  • Inflammatory pseudotumor of pelvic lymph nodes.

    abstract:BACKGROUND:Inflammatory pseudotumor is a rare benign cause of lymphadenopathy previously reported in several anatomic locations that can simulate malignant neoplasm. CASE:A postmenopausal woman presented with abdominal pain, generalized malaise, leukocytosis, and intermittent fevers up to 102 degrees F. A 5-day course...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000201973.13715.ee

    authors: Spannuth WA,Leath CA 3rd,Conner MG,Alvarez RD

    更新日期:2006-09-01 00:00:00

  • Hand-held computer operating system program for collection of resident experience data.

    abstract:OBJECTIVE:To describe a system for recording resident experience involving hand-held computers with the Palm Operating System (3 Com, Inc., Santa Clara, CA). PROGRAM DESCRIPTION:Hand-held personal computers (PCs) are popular, easy to use, inexpensive, portable, and can share data among other operating systems. Residen...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)01015-2

    authors: Malan TK,Haffner WH,Armstrong AY,Satin AJ

    更新日期:2000-11-01 00:00:00

  • Ectopic pregnancy risk with assisted reproductive technology procedures.

    abstract:OBJECTIVE:To assess the ectopic pregnancy risk among women who conceived with assisted reproductive technology (ART) procedures. METHODS:The ectopic rate for ART pregnancies was calculated from population-based data of pregnancies conceived with ART in U.S. clinics in 1999-2001. Variation in ectopic risk by patient an...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000196503.78126.62

    authors: Clayton HB,Schieve LA,Peterson HB,Jamieson DJ,Reynolds MA,Wright VC

    更新日期:2006-03-01 00:00:00

  • Birth Behind Bars: The Need for Labor Support in the Incarcerated Population.

    abstract::The population of women within carceral systems is growing rapidly. A portion of these individuals are pregnant and will deliver while incarcerated. Although shackling laws for pregnant persons have improved, incarcerated patients are forced to labor without the support of anyone but a carceral officer and their medic...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000004119

    authors: Dahl CM,Geynisman-Tan JM,Premkumar A

    更新日期:2020-11-01 00:00:00

  • United States Medical Licensure Examination step 1 scores and obstetrics-gynecology clerkship final examination.

    abstract:OBJECTIVE:To determine if scores from first attempts at the United States Medical Licensure Examination step 1 correlated with obstetrics-gynecology examination scores and identified students at risk of failure. METHODS:All students in obstetrics-gynecology clerkships at the University of Illinois at Chicago from July...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(99)00477-9

    authors: Myles TD

    更新日期:1999-12-01 00:00:00

  • Successful term pregnancy after bilateral uterine artery embolization for postpartum hemorrhage.

    abstract:BACKGROUND:Selective bilateral uterine artery embolization has been used since the 1970s for the conservative treatment of postpartum hemorrhage. The fertility rate after the embolization procedure is yet to be determined. CASE:A 30-year-old woman presented with placental abruption and subsequently delivered preterm a...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/s0029-7844(03)00230-8

    authors: Wang H,Garmel S

    更新日期:2003-09-01 00:00:00

  • Treatment of common gynecologic-endocrinologic symptoms by allergy management procedures.

    abstract::The technique of managing allergies by optimum-dose (provocative neutralization) testing and treatment using aqueous progesterone has been studied in 132 women having progesterone-related symptoms due to the menstrual cycle, pregnancy, or exogenous hormone administration. When extremely small doses of progesterone (0....

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Mabray CR,Burditt ML,Martin TL,Jaynes CR,Hayes JR

    更新日期:1982-05-01 00:00:00

  • Maternal cigarette smoking and placenta previa.

    abstract:OBJECTIVE:To identify the relationship between maternal cigarette smoking and ultrasound-confirmed placenta previa. METHODS:A matched case-control design was used. Cases were drawn from the New England Medical Center and Cambridge Hospital from July 1992 through March 1994. Each case was delivered by cesarean after 24...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00471-8

    authors: Chelmow D,Andrew DE,Baker ER

    更新日期:1996-05-01 00:00:00

  • Uterine leiomyosarcoma metastatic to the thyroid.

    abstract:BACKGROUND:Uterine leiomyosarcoma is an aggressive tumor that has a propensity for distant metastasis. Distant sites of spread include the lung, liver, brain, and bone. CASE:A woman in her 5th decade was diagnosed with stage IV leiomyosarcoma of the uterus. Distant metastasis in the chest was confirmed by thoracotomy ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(02)02191-9

    authors: Leath CA 3rd,Huh WK,Straughn JM Jr,Conner MG

    更新日期:2002-11-01 00:00:00

  • Effects of the dopamine antagonist veralipride on hot flushes and luteinizing hormone secretion in postmenopausal women.

    abstract::The effects on hot flushes of the dopamine antagonist Veralipride versus placebo were investigated in a randomized double-blind study of postmenopausal healthy women (N = 20 in each group). Cutaneous temperature recording and plasma LH pulsatility were studied in eight patients from each group. Veralipride administrat...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Melis GB,Gambacciani M,Cagnacci A,Paoletti AM,Mais V,Fioretti P

    更新日期:1988-11-01 00:00:00

  • Second-Trimester Fetal Loss in a Patient With Hyperemesis Gravidarum Complicated by Refeeding Syndrome.

    abstract:BACKGROUND:Refeeding syndrome is a rare constellation of electrolyte abnormalities after reintroduction of glucose during an adaptive state of starvation and malnutrition, resulting in fluid shifts, end-organ damage, and, potentially, death. We present a case of fetal death in a patient with hyperemesis gravidarum comp...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003276

    authors: Mayer KH,McGill AL

    更新日期:2019-06-01 00:00:00

  • Prediction of preterm delivery in the second trimester.

    abstract:OBJECTIVE:The aim of this study was to estimate the probability of spontaneous delivery at 34 weeks or less according to cervical assessment by transvaginal scan associated with previous obstetric history. METHODS:Ultrasound transvaginal cervical length and presence of funneling were evaluated in 1,958 singleton pregn...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000154157.22500.1d

    authors: de Carvalho MH,Bittar RE,Brizot Mde L,Bicudo C,Zugaib M

    更新日期:2005-03-01 00:00:00

  • Effects of Shared Decision Making on Opioid Prescribing After Hysterectomy.

    abstract:OBJECTIVE:To evaluate the effects of shared decision making using a simple decision aid for opioid prescribing after hysterectomy. METHODS:We conducted a prospective quality initiative study including all patients undergoing hysterectomy for benign, nonobstetric indications between March 1, 2018, and July 31, 2018, at...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003468

    authors: Vilkins AL,Sahara M,Till SR,Ceci C,Howard R,Griffith KC,Waljee JF,Lim CS,Skinner BD,Clauw DJ,Brummett CM,As-Sanie S

    更新日期:2019-10-01 00:00:00

  • Preoperative vaginal preparation with povidone-iodine and the risk of postcesarean endometritis.

    abstract:OBJECTIVE:Postcesarean endometritis and wound infection remain significant morbidities, despite use of strategies to prevent these complications. We investigated the effect of preoperative vaginal preparation with povidone-iodine as a preventive intervention against postcesarean endometritis and wound infection. METHO...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000164032.16599.7e

    authors: Starr RV,Zurawski J,Ismail M

    更新日期:2005-05-01 00:00:00

  • Cost savings of red cell salvage during cesarean delivery.

    abstract:OBJECTIVE:To use decision analysis to evaluate whether and under what conditions routine setup of intraoperative cell salvage during cesarean delivery is cost-saving. METHODS:We developed a decision model to compare costs associated with two strategies for cesarean delivery: 1) routine setup of intraoperative cell sal...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000465

    authors: Albright CM,Rouse DJ,Werner EF

    更新日期:2014-10-01 00:00:00

  • Hormones and sexuality: effect of estrogen and progestogen.

    abstract::This study was planned to determine the effects of estrogen and progestogen on female sexual behavior. Forty-nine women who had undergone hysterectomy and bilateral salpingo-oophorectomy took part in a double-blind placebo-controlled cross-over study. Over a 12-month period each woman received 3 months each of ethinyl...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dennerstein L,Burrows GD,Wood C,Hyman G

    更新日期:1980-09-01 00:00:00

  • Association between vaginal birth after cesarean delivery and primary cesarean delivery rates.

    abstract:OBJECTIVE:To estimate the association between vaginal birth after cesarean delivery (VBAC) rates and primary cesarean delivery rates in California hospitals. METHODS:Hospital VBAC rates were calculated using birth certificate and discharge data from 2009, and hospitals were categorized by quartile of VBAC rate. Multiv...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3182a91e0f

    authors: Rosenstein MG,Kuppermann M,Gregorich SE,Cottrell EK,Caughey AB,Cheng YW

    更新日期:2013-11-01 00:00:00

  • Peripheral subcutaneous vulvar stimulation in the management of severe and refractory vulvodynia.

    abstract:BACKGROUND:Vulvodynia is a complex and multifactorial clinical condition with severe pain that occurs in the absence of visible infectious, inflammatory, neoplastic, or neurological findings. CASE:A 35-year-old woman with 3 years of dysesthetic vulvodynia tried conventional and interventional medical treatment with in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/aog.0b013e31827c60f8

    authors: De Andres J,Sanchis-Lopez N,Asensio-Samper JM,Fabregat-Cid G,Dolz VM

    更新日期:2013-02-01 00:00:00

  • Pragmatic factors influencing the detection of Neisseria gonorrhoeae.

    abstract::The effects of the suboptimal temperature caused by delayed incubation or prolonged transport on the recovery of Neisseria gonorrhoeae were studied in 2 separate patient populations. The individual components of the John E. Martin Biological Environmental Chamber were used to define more precisely other variables that...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Monif GR,Jordan PA,Thompson JL,Shaara R

    更新日期:1982-05-01 00:00:00