[Moducrin--a new combined preparation in the treatment of hypertension (author's transl)].

Abstract:

:A product combining 25 mg hydrochlorothiazide, 2.5 mg amiloride hydrochloride and 10.0 mg timolol maleate (Moducrin) was tested in 20 previously untreated hypertensive persons. The systolic blood pressure before treatment was 199.1 +/- 24.8 mmg Hg and after treatment 149.1 +/- 19.1 mm Hg. Diastolic blood pressure showed a drop from 120.9 +/- 11.9 mm Hg to 92.2 +/- 13.3 mm Hg. Both decreases were highly significant (p less than 0.01). The heart rate, moreover, was reduced during treatment from 81.5 +/- 11.1 beats per minute to 66.8 +/- 9.25 beats (p less than 0.01). Haemoglobin, haematocrit and serum uric acid showed significant changes, but did not reach pathological ranges. Treatment had to be stopped in only one case in this study because of incipient asthmatic bronchitis. We conclude that this combination drug has a very good antihypertensive effect and is well tolerated.

journal_name

Wien Klin Wochenschr

authors

Prachar H,Nobis H,Pollak H,Enenkel W

subject

Has Abstract

pub_date

1981-08-07 00:00:00

pages

489-92

issue

15

eissn

0043-5325

issn

1613-7671

journal_volume

93

pub_type

杂志文章
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  • Cardiac rehabilitation in Austria: short term quality of life improvements in patients with heart disease.

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  • [Value of consistent after care in stomach cancer].

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    更新日期:1987-06-12 00:00:00

  • Outcome in patients with intracerebral hemorrhage: predictors of survival.

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    authors: Karnik R,Valentin A,Ammerer HP,Hochfelner A,Donath P,Slany J

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  • [Alcohol-induced type V hyperlipidemia in relation to changes in the chemical composition of HDL2].

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  • 3-D Conformal radiotherapy of localized prostate cancer within an Austrian-German multicenter trial: a prospective study of patients' acceptance of the rectal balloon during treatment.

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  • Decreased cutaneous vitamin D-synthesis in heavily melanized individuals: a rare cause for pathologic fractures of the hip.

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  • Misdiagnosis of pulmonary embolism in patients with allergic reaction--the importance of prior probability of disease.

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    doi:10.1007/BF03040891

    authors: Janata K,Prokop M,Schaefer-Prokop C,Laggner AN

    更新日期:2003-10-31 00:00:00

  • Detection of atrial shunt lesions with a single echocardiographic parameter.

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  • Regression of atherosclerosis: which components regress and what influences their reversal.

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    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,meta分析

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  • Potentially inappropriate medication in geriatric patients: the Austrian consensus panel list.

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  • [Disseminated peritoneal leiomyomatosis].

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    authors: Lösch A,Kainz C,Gitsch G,Breitenecker G

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  • [Familial hypophosphatemia].

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  • [3-dimensional scintigraphy of the brain: single photon emission computerized tomography].

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    doi:

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  • "Wiener klinische Wochenschrift": publication patterns 1990-2000.

    abstract::The impact factor (Institute for Scientific Information, ISI, Philadelphia, PA, USA) is a widespread used and acknowledged source for judging the quality of a researcher. In addition the "Science Citation Index (SCI)" [Institute for Scientific Information (ISI)] provides the scientific community with a citations datab...

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  • Effects of immune modulation therapy in the first Croatian infant diagnosed with Pompe disease: a 3-year follow-up study.

    abstract::Pompe disease is a storage disorder characterized by deficient or absent activity of the enzyme acid alpha-glucosidase. As a result of ineffective metabolism, glycogen accumulates in muscle tissues. Patients with a classic infantile-onset form present by the first few months of life with hypertrophic cardiomyopathy an...

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    pub_type: 杂志文章

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    authors: Markic J,Polic B,Stricevic L,Metlicic V,Kuzmanic-Samija R,Kovacevic T,Ivkosic IE,Mestrovic J

    更新日期:2014-02-01 00:00:00

  • [The "Asthma Programme" (author's transl)].

    abstract::The "asthma programme", the product of teamwork between the 1st Department of Dermatology and the 2nd Department of Medicine is presented. It contains all examinations necessary for the diagnosis of bronchial asthma: case history, skin test, IgE, RAST, lung function test, inhalative provocation test. The value of each...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Jarisch R,Kummer F,Oppolzer R

    更新日期:1975-11-28 00:00:00

  • [Left ventricular function in young type I diabetic patients. A Doppler echocardiography study].

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    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

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  • Elecsys TSH, FT4, T4, T-uptake, FT3 and T3. Clinical results of a multicentre study.

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    pub_type: 杂志文章,多中心研究

    doi:

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    更新日期:1998-01-01 00:00:00

  • Premature rupture of membranes with oligo- or anhydramnios before 24 weeks of gestation and the chances of fetal survival.

    abstract:UNLABELLED:Rupture of the membranes before the fetus has achieved viability within the womb is an event of enormous importance for both mother and physician. The potential outcome ranges from fetal death, a frequent occurrence, to a severely disabled life or a happy (but rare) birth without any mental or physical retar...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-004-0246-2

    authors: Tews G,Shebl O,Ebner T,Sommergruber M,Jesacher K

    更新日期:2004-10-30 00:00:00

  • [Photoprotection by psoralen-UVA therapy: experimental and clinical results (author's transl)].

    abstract::Studies on minimum erythema doses, histological investigations and quantitative determination of DNA repair synthesis of epidermal cells revealed that a tan induced by the oral administration of 8-methoxy-psoralen (8-MOP) and subsequent UVA irradiation gives protection from the erythemogenic effects of sunlight, dimin...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Gschnait F,Brenner W,Wolff K

    更新日期:1979-12-21 00:00:00

  • Pancreatic incidentalomas: a growing clinical challenge exemplified by an intrapancreatic accessory spleen.

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  • Diagnosis and treatment of hypothyroidism in old people : A new old challenge.

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    doi:

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