Abstract:
UNLABELLED:Rupture of the membranes before the fetus has achieved viability within the womb is an event of enormous importance for both mother and physician. The potential outcome ranges from fetal death, a frequent occurrence, to a severely disabled life or a happy (but rare) birth without any mental or physical retardation for the child. The aim of the present investigation was to provide the consulting physician with valid data, enabling him/her to make a realistic assessment of the risks and to inform the patient accordingly. METHOD:In a retrospective analysis, we followed 36 cases with spontaneous rupture of the maternal membranes and development of oligo-/anhydramnios before 24 weeks of gestation. The patients had been treated between January 1994 and 2004. In a more detailed assessment, the patient cohort was divided into one group of women with rupture between 10 and 20 weeks of gestation and another group with a gestational age between start of week 21 and end of week 23. RESULTS:Of the 36 children, seven (19.4%) survived initially, with two of the seven survivors dying subsequently. Among women with amniorrhexis before week 21 of gestation, only three of the 26 children survived, while four of 10 children survived among women with premature rupture of membranes between 21 and 23 weeks of gestation (p = 0.053) No case of mental retardation could be observed in the surviving children. Perinatal outcome was found to be significantly different in the presence of amnionitis (3/27) compared to the group without this event (4/9) (p = 0.028). CONCLUSIONS:Because of the poor fetal outcome, termination of an ongoing pregnancy must also be considered in counseling the mother. If the mother decides to continue her pregnancy, amnionitis will be the most critical factor for ultimate termination of pregnancy.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Tews G,Shebl O,Ebner T,Sommergruber M,Jesacher Kdoi
10.1007/s00508-004-0246-2subject
Has Abstractpub_date
2004-10-30 00:00:00pages
692-4issue
19-20eissn
0043-5325issn
1613-7671journal_volume
116pub_type
杂志文章abstract::The effects of etazolate and cartazolate, two pyrazolopyridine derivatives with anxiolytic actions, on the receptor binding of gamma-aminobutyric acid (GABA) was studied in vitro using membrane fractions prepared from rat brain. Both compounds increased the specific GABA receptor binding. This effect was markedly enha...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract:UNLABELLED:Discussion of selection criteria for liver transplantation in alcoholics has been controversial. The concern that there might be a return to alcohol misuse after transplantation which would cause non-compliance with post-transplantation management is not supported by recent reports. Six months of abstinence ...
journal_title:Wiener klinische Wochenschrift
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journal_title:Wiener klinische Wochenschrift
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journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Wiener klinische Wochenschrift
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pub_type: 杂志文章
doi:
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journal_title:Wiener klinische Wochenschrift
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journal_title:Wiener klinische Wochenschrift
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journal_title:Wiener klinische Wochenschrift
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pub_type: 杂志文章
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journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
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