Abstract：
:Both IMP and HMPAO are lipophilic substances with high blood brain barrier permeability and sufficiently long constant retention in the brain parenchyma to enable SPECT to be carried out with a computer controlled Gamma camera. Both tracers are almost completely cleared from the blood during a single passage through the brain. Hence, the regional distribution of activity in the brain is proportional to the regional cerebral blood flow. Computerized acquisition and data processing result in 16 mm thick tomograms at a spatial resolution of 12 mm, which enable clinicians to detect and characterize the pathogenesis and the development of cerebral disorders in terms of altered function. At present, SPECT can be used in daily clinical routine (final SPECT images are available 30 min after the investigation) in cerebrovascular diseases and, because of the coupling of metabolism to cerebral blood flow, in disturbances of cerebral blood flow due to pathological changes of brain metabolism, i.e. in epilepsy and in degenerative disorders. The forthcoming application of physiologically highly specific tracers (e.g. receptor ligands) as a means of studying the distribution of receptors and drugs in the brain will further enlarge the eventual role of SPECT in clinical management.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Deisenhammer E,Höll Ksubject
Has Abstractpub_date
1988-06-10 00:00:00pages
392-404issue
12eissn
0043-5325issn
1613-7671journal_volume
100pub_type
杂志文章,评审abstract：:Imaging techniques for first line investigation of diseases of the thyroid gland are sonography (US) and scintigraphy, followed in dedicated cases by magnetic resonance imaging (MRI). Malignant lesions are generally hypoechoic on US with calcifications visible in some cases. The appearance of lymph node metastases is ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：:A case of aneurysm of the abdominal aorta is presented. The clinical picture was suggestive of a pancreatic cyst, but the correct diagnosis was made on abdominal ultrasonography. Early diagnosis of the condition allowed removal of the aneurysm and implantation of a femoral by-pass. The value of ultrasonography in diag...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-01-05 00:00:00
abstract：BACKGROUND:Autologous hematopoietic stem cell transplantation (aHSCT) is the recommended standard upfront treatment for transplant eligible myeloma patients. Considering possible complications related to chemotherapy-cytokine mobilization, cytokine-alone mobilization is often used. We compared mobilization with filgras...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00508-017-1205-z
更新日期：2017-08-01 00:00:00
abstract：:As in other organs, homeostatic mechanisms become insufficient in the aging brain, in part because of reduced activity of various neurotransmitter systems. Counter-regulatory processes are therefore reduced and reactions to drugs may be increased. Aside from these pharmacodynamic mechanisms, the increased toxicity of ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-05 00:00:00
abstract：:Doping is a phenomenon which in the past years through the various incidences in professional cycling has come more and more into the focus of the public interest. Whilst in the young past the problems were to define the term "doping" exactly, today's problem is to prevent adolescents and children of doping. This shal...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-010-1383-4
更新日期：2010-06-01 00:00:00
abstract：:LCS level of lactate and clinical status correlate well during the initial stage of encephalomalacia (2nd-4th day) and during a period of 12 to 14 days after infarction LCS level of lactate may, therefore, be regarded as important parameter for short-term prognosis of encephalomalcia. The use of a semiquantitative cli...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1980-09-12 00:00:00
abstract：:Within the last years, an increasing trend of voyages to Central and Eastern European destinations could be observed. However, Europeans travelling within their own continent do not consider themselves as travellers exposed to possibly travel-associated infections since problem awareness among tourists as well as cons...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-005-0442-8
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:Down syndrome is the most commonly occurring chromosomal condition with a prevalence of 11.2-10000 life-births in Europe. The most important concern consists of various degrees of intellectual disability and sensory deficits. The overall prevalence of ophthalmologic abnormalities has been reported to be as h...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0750-6
更新日期：2015-08-01 00:00:00
abstract：:Two major features of atherosclerosis may be distinguished: (a) atherosis caused by lipid infiltration in cells and extracellularly and (b) sclerosis caused by connective tissue deposition and by functional disturbance of the endothelium, leading to impairment of endothelium-derived relaxing factor (EDRF)-release and ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Clear cell carcinoma arising in a cesarean section scar is extremely rare. Due to the rarity of the tumor, treatment strategies still need to be further elucidated. We report a case of a woman with a clear cell carcinoma of 10 cm outside the abdominal cavity in her cesarean section scar. Staging surgery revealed two l...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-014-0619-0
更新日期：2015-01-01 00:00:00
abstract：:Alcohol consumption is one of the most common causes of secondary hyperlipidaemia in man, but not all alcohol addicts display hyperlipidaemia. 10 healthy male controls were compared with three groups of patients. The first group consisted of 9 heavy drinkers exhibiting type V hyperlipidaemia under the influence of alc...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1985-03-29 00:00:00
abstract：:Clinical and genetic investigations were performed on seven members of a family suffering from multiple hereditary fibromatosis. These studies indicate that the responsible gene appears to be coupled and transmitted with that of the rhesus system, located at chromosome one. The diagnosis, differential diagnosis and th...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1976-02-06 00:00:00
abstract：:The influence of a 4 week course of balneotherapeutic treatment in Bad Hall on different blood parameters and on the activity of the antioxidative enzymes glutathione peroxidase (GSH-Px), catalase and superoxide dismutase (SOD) was examined in diabetics. The patients were divided into 2 groups. One group underwent an ...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-01-01 00:00:00
abstract：:Nutritional anaemias are common in tropical areas. The commonest cause is iron deficiency, which mainly arises from impaired absorption of iron from food. Substances which inhibit iron absorption in various diets play an important role in the pathogenesis of iron deficiency anaemia. Iron deficiency is further aggravat...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1984-07-06 00:00:00
abstract：OBJECTIVE:To present our innovative surgical method for prevention of early preterm delivery in women with cervical dilatation and membrane herniation. STUDY DESIGN:A woman in the 24th gestational week, with membrane herniation due to a 2-3 cm dilatation of the cervix, is presented. The surgical technique for occlusio...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-006-0550-0
更新日期：2006-01-01 00:00:00
abstract：:The therapeutic effect of n-dipropylacetate (DPA) is described in 20 patients with cerebral or spinal spasticity. Improvement was ween in 8 out of 11 patients with cerebral spasticity, 3 out of 5 patients with spinal spasticity and 3 out of 4 cases who had sustained perinatal damage. Satisfactory clinical amelioration...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1976-12-10 00:00:00
abstract：:Recent advances in the knowledge of human immunodeficiency virus (HIV) replication and transmission as well as the emergence of effective antiretroviral therapies are leading to longer survival times for HIV-infected individuals. As a result, organ related manifestations of late stage HIV infection, including HIV-rela...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-005-0313-3
更新日期：2005-02-01 00:00:00
abstract：:A diagram is presented which enables the continuous recording of biometric values from the earliest possible time right up to the end of pregnancy. It has been tested in practice. The duration of pregnancy and fetal development and growth can be evaluated from the diagram. ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-10-12 00:00:00
abstract：BACKGROUND:Hearing loss is the most common sensory disorder in developed countries and leads to a severe reduction in quality of life. In this uncontrolled case series, we evaluated the auditory development in patients suffering from congenital nonsyndromic hearing impairment related to preterm birth. METHODS:Six pati...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-014-0653-y
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Arthroscopic reconstruction is a standard surgical procedure in cases of symptomatic knee instability due to rupture of the anterior cruciate ligament. Bone-tendon-bone and hamstring tendon grafts are both in use for anterior cruciate ligament reconstruction. There are no significant differences between the ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00508-010-1340-2
更新日期：2010-05-01 00:00:00
abstract：:1589 patients treated between 1965 and 1985 at the First Surgical Department of Vienna University were investigated to answer the following questions: 1. Development of postoperative mortality. 2. Is a palliative gastrectomy indicated? 3. Does gastrectomy en principe improve survival? 4. Quality of life after total ga...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1987-06-12 00:00:00
abstract：OBJECTIVE:The aim of our study was to determine whether a difference exists in expression of corticotropin-releasing hormone receptor-R1 (CRH-R1) and corticotropin-releasing hormone receptor-R2 (CRH-R2) in fetal membranes of preterm and term women with or without labor. MATERIAL AND METHODS:Small pleces of fetal membr...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2002-12-30 00:00:00
abstract：:From 1977 to 1982 a prospective randomized double-blind study comparing transfer-factor (TF) versus placebo was conducted in invasive cervical cancer patients after radical surgery and irradiation. The husbands of the cancer patients were selected as leukocyte donors for TF preparations. 60 patients entered the study;...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-10-28 00:00:00
abstract：BACKGROUND:The 6 min pegboard and ring test (6PBRT) is a valid and reproducible test of unsupported arm exercise endurance. The aim of this study was to determine the associations between the 6PBRT, activities of daily living (ADL) and hemoglobin levels in chronic obstructive pulmonary disease (COPD). METHODS:This stu...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-020-01635-8
更新日期：2020-03-25 00:00:00
abstract：:Hypertonic-hyperoncotic solutions are a supplementation to conventional fluid regimens in the management of hypovolemia due to trauma, hemorrhage and shock. In this review the possible modes of action of these solutions are discussed and their efficacy both in experimental and clinical settings is presented. Possible ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:The therapeutic potential of sodium dichloroacetate (DCA) formerly called vitamin B 15, has already been under investigation for the past few years. The predominant property of DCA underlying its therapeutic action is activation of pyruvate dehydrogenase. The potential therapeutic use of DCA in the treatment of lactic...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1990-02-02 00:00:00
abstract：:Plasma exchange (PE) is the treatment of choice in emergencies arising in patients suffering from the hyperviscosity syndrome, factor VIII antibody haemophilia, autoimmune haemolytic anaemia or post-transfusion purpura. Apart from these clear indications, the efficacy of PE in other hematological disorders such as thr...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1985-02-01 00:00:00
abstract：:Primary endoscopic removal of bile duct stones is an established method of treatment. However, the extraction of stones is impossible in about 10% of cases despite successful endoscopic papillotomy and manual lithotripsy. Over a period of two years extracorporeal shock-wave lithotripsy (ESWL) was performed in 32 patie...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1989-09-29 00:00:00
abstract：:A large variety of methods and a wide range of products from several manufacturers are available for IgE-based in vitro allergy testing. In the large majority of cases, the attending physician lacks information about the devices and products used in the laboratory performing the tests. To determine the comparability a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-014-0594-5
更新日期：2014-10-01 00:00:00
abstract：:Intravenous application of bisphosphonates (BP) represents an established therapeutic strategy of tumor-associated bone metastasis and severe hypercalcemia. Patients can develop osteonecrosis of the jaw (ONJ) as a side effect of this therapy. The diagnosis of ONJ is based on three criteria: a) patients have been or ar...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-008-1002-9
更新日期：2008-01-01 00:00:00
