Kidney protection against ischemia/reperfusion injury by myofibrillogenesis regulator-1.

abstract：:Collapsing glomerulopathy is a pattern of renal injury that is seen in association with human immunodeficiency virus (HIV) infection. Patients with this HIV-associated nephropathy (HIVAN) present nephrotic syndrome and rapid deterioration of the renal function. There is no proven effective therapy for HIVAN, and the m...

journal_title：American journal of nephrology

authors： Morales E,Martinez A,Sánchez-Ayuso J,Gutierrez E,Mateo S,Martínez MA,Herrero JC,Praga M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND/AIMS:In chronic hemodialysis patients, we evaluated determinants of repetitive ventricular tachyarrhythmias which included late potentials and heart rate variability. METHODS:We compared the presence of late potentials and heart rate variability obtained by ambulatory electrocardiogram (ECG), findings of ec...

journal_title：American journal of nephrology

authors： Tamura K,Tsuji H,Nishiue T,Tokunaga S,Yajima I,Higashi T,Iwasaka T

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:HFE protein controls iron absorption and cycling, and HFE mutations influence iron status. The aim was to evaluate the effect of the HFE genotype on the need for iron and erythropoietin in Italian hemodialysis patients. METHODS:Ninety-six prevalent patients were evaluated at the time of enrolment and p...

journal_title：American journal of nephrology

authors： Valenti L,Valenti G,Como G,Santorelli G,Dongiovanni P,Rametta R,Fracanzani AL,Tavazzi D,Messa PG,Fargion S

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Chronic metabolic acidosis is a common metabolic disturbance and its clinical impact can be severe and extensive. The role and the change of the intrarenal renin-angiotensin system (RAS) during metabolic acidosis are uncertain, and whether acidosis can evoke inflammation remains unclear. METHODS:Male Spragu...

journal_title：American journal of nephrology

authors： Ng HY,Chen HC,Tsai YC,Yang YK,Lee CT

更新日期：2011-01-01 00:00:00

abstract：:To evaluate the therapeutic effect of recombinant human alpha-interferon (alpha-IFN) on hepatitis B virus associated glomerulonephritis (HBV-GN) and the relationship between the seroconversion of viral antigens and the change of proteinuria, the hepatitis B viral markers and urinary protein were monitored during alpha...

journal_title：American journal of nephrology

authors： Chung DR,Yang WS,Kim SB,Yu E,Chung YH,Lee Y,Park JS

更新日期：1997-01-01 00:00:00

abstract：:This study was carried out to find out whether Ramadan fasting would affect the renal function in kidney transplant recipients with normal or impaired graft function. Twenty-three transplant recipients, 17 with a normal function and 6 with an impaired but stable function with plasma creatinine levels not exceeding 300...

journal_title：American journal of nephrology

authors： Abdalla AH,Shaheen FA,Rassoul Z,Owda AK,Popovich WF,Mousa DH,al-Hawas F,al-Sulaiman MH,al-Khader AA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Obesity is an independent risk factor for morbidity and mortality in cardiovascular diseases not only in the general population, but also in hemodialysis (HD) patients. We previously reported that an increased visceral fat area (VFA) determined using computed tomography (CT) scans was associated with atheros...

journal_title：American journal of nephrology

authors： Okamoto T,Morimoto S,Ikenoue T,Furumatsu Y,Ichihara A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN). METHODS:A total of 525 type 2 diabetics were enrolled to participate in this prospective observational study. ACE and AGT gene polymorphisms were analyzed by polymerase ...

journal_title：American journal of nephrology

authors： Tien KJ,Hsiao JY,Hsu SC,Liang HT,Lin SR,Chen HC,Hsieh MC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:End-stage renal disease (ESRD) is a disease with an aging population and a high prevalence of cognitive impairment affecting quality of life, health care costs and mortality. Structural changes in the brain with decreased white matter integrity have been observed in ESRD. Understanding the changes in cogniti...

journal_title：American journal of nephrology

authors： Gupta A,Lepping RJ,Yu AS,Perea RD,Honea RA,Johnson DK,Brooks WM,Burns JM

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress and inflammation are known to play central roles in the development of diabetic nephropathy (DN). Febuxostat is a novel non-purine xanthine oxidase (XO)-specific inhibitor developed to treat hyperuricemia. In this study, we investigated whether febuxostat could ameliorate DN via renoprotecti...

journal_title：American journal of nephrology

authors： Lee HJ,Jeong KH,Kim YG,Moon JY,Lee SH,Ihm CG,Sung JY,Lee TW

更新日期：2014-01-01 00:00:00

abstract：:We retrospectively reviewed the course of 1,000 renal transplants performed in 835 recipients (758 nondiabetics) to assess the incidence of new onset posttransplant diabetes in former nondiabetics. A total of 119 (15.7%) recipients manifested posttransplant diabetes, of whom 64 (53.8%) became hyperglycemic within 3 we...

journal_title：American journal of nephrology

authors： Friedman EA,Shyh TP,Beyer MM,Manis T,Butt KM

更新日期：1985-01-01 00:00:00

abstract：:Erythropoietin-stimulating agent (ESA) hyporesponsiveness is aggravated by chronic inflammation in maintenance hemodialysis (MHD) patients. Dyslipidemia is prevalent in MHD patients. Statin therapy has been demonstrated to not only be effective in lowering lipid levels, but also numerous pleiotropic effects including ...

journal_title：American journal of nephrology

authors： Chiang CK,Yang SY,Peng YS,Hsu SP,Pai MF,Huang JW,Hung KY,Wu KD

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP), which reflects chronic inflammation, is a strong predictor of cardiovascular mortality in hemodialysis patients. We investigated whether persistent elevation of CRP is associated with cardiac function and morphology in patients maintained on hemodialysis. METHODS:Predialysis high-s...

journal_title：American journal of nephrology

authors： Kim BS,Jeon DS,Shin MJ,Kim YO,Song HC,Lee SH,Kim SY,Choi EJ,Chang YS,Bang BK

更新日期：2005-05-01 00:00:00

abstract：:This report reviews the features of 149 cases of renal allograft rupture, while adding a detailed description of 3 more cases to the English literature. From November, 1973 to November, 1979, 3 cases of renal allograft rupture occurred in 100 renal transplants performed at Research Medical Center, Kansas City, Mo., an...

journal_title：American journal of nephrology

authors： Thukral R,Mir AR,Jacobson MP

更新日期：1982-01-01 00:00:00

abstract：:An 18-year-old woman complained of fever and edema and was admitted to Showa University Hospital for treatment of thrombocytopenia and deteriorating renal function. Laboratory studies demonstrated the presence of lupus anticoagulant (LA), prolongation of prothrombin time, hemolytic anemia, a negative Coombs' test, the...

journal_title：American journal of nephrology

authors： Sakaguchi S,Kitazawa K,Watanabe M,Mukai K,Totsuka D,Shibata T,Sugisaki T

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:To evaluate the association of dialysate interleukin-6 (IL-6), a marker of ongoing peritoneal inflammation, with the alteration of peritoneal solute transport rate (PSTR) in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS:Stable CAPD patients were enrolled in the present study. A total of...

journal_title：American journal of nephrology

authors： Yang X,Zhang H,Hang Y,Yan H,Lin A,Huang J,Ni Z,Qian J,Fang W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Death with a functioning graft (DWF) has been reported as a major cause of graft loss after renal transplantation. It has been reported to occur in 9-30%. METHODS:From March 1976 to January 2002, a total of 1400 living donor renal transplants were performed in our center. Out of 257 reported deaths among ou...

journal_title：American journal of nephrology

authors： El-Agroudy AE,Bakr MA,Shehab El-Dein AB,Ghoneim MA

更新日期：2003-05-01 00:00:00

abstract：:Serum levels of soluble interleukin-2 receptors (IL2R) and of beta 2-microglobulin (beta 2M) were studied with the immunoenzymatic technique in 38 patients with primary glomerulonephritis (GN), in 10 patients with essential hypertension (EH) and in 30 healthy subjects. IL2R correlated with beta 2M (p < 0.05). IL2R and...

journal_title：American journal of nephrology

authors： Rollino C,Roccatello D,Amprimo MC,Cavalli G,Aimo G,Beltrame G,Basolo B,Martina G,Piccoli G

更新日期：1993-01-01 00:00:00

abstract：:A meeting on the History of Nephrology is an opportunity to discuss the links between science and faith which were split until the 6th century. However, this was changed by Cassiodorus and monasticism. From the times of Abbot Bertario (died 883 AD) in Montecassino, medicine was regarded as an art and a science. Codex ...

journal_title：American journal of nephrology

authors： D'Onorio B

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...

journal_title：American journal of nephrology

authors： Kumar S,Khosravi M,Massart A,Potluri M,Davenport A

更新日期：2013-01-01 00:00:00

abstract：:We carried out a prospective 2-year study on the transmission of human immunodeficiency virus (HIV) infection in a chronic dialysis unit with a high prevalence (11%) of the infection. Only 1 of 45 HIV-negative patients seroconverted, and this was related to the administration of contaminated blood. We conclude that cu...

journal_title：American journal of nephrology

authors： Perez GO,Ortiz C,De Medina M,Schiff E,Bourgoignie JJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Telomere attrition is a novel risk factor for cardiovascular disease. Studies of telomere length in relation to kidney function are limited. We explored the association of kidney function with telomere length and telomere shortening. METHODS:The Heart and Soul Study is a longitudinal study of patients with ...

journal_title：American journal of nephrology

authors： Bansal N,Whooley MA,Regan M,McCulloch CE,Ix JH,Epel E,Blackburn E,Lin J,Hsu CY

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Serum creatinine (SCr) levels are decreased following traumatic amputation, leading to the overestimation of glomerular filtration rate (GFR). β-Trace protein (BTP) and β2-microglobulin (B2M) strongly correlate with measured GFR and have not been studied following amputation. We hypothesized that BTP and B2M...

journal_title：American journal of nephrology

authors： Little DJ,Yuan CM,Thurlow JS,Gounden V,Doi SQ,Pruziner A,Abbott KC,Theeler BJ,Olson SW

更新日期：2015-01-01 00:00:00

abstract：:The administration of calcium-blocking drugs exerts a natriuretic response. Acute studies in isolated perfused kidneys and in experimental animals, as well as in man, consistently demonstrate diuresis, natriuresis, calciuresis, and generally kaliuresis, even in the face of arterial blood pressure reduction. Clearance ...

journal_title：American journal of nephrology

authors： Luft FC

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Dietary sodium may influence cognitive function through its effects on cerebrovascular function and cerebral blood flow. METHODS:The aim of this study was to evaluate the association of dietary sodium intake with cognitive decline in community-dwelling older adults. We also evaluated the associations of die...

journal_title：American journal of nephrology

authors： Nowak KL,Fried L,Jovanovich A,Ix J,Yaffe K,You Z,Chonchol M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Vascular calcification is seen in most patients on dialysis and is strongly associated with cardiovascular mortality. Vascular calcification is promoted by phosphate, which generally reaches higher levels in hemodialysis than in peritoneal dialysis. However, whether vascular calcification develops less in pe...

journal_title：American journal of nephrology

authors： Jansz TT,van Reekum FE,Özyilmaz A,de Jong PA,Boereboom FTJ,Hoekstra T,Verhaar MC,van Jaarsveld BC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Upregulation of transforming growth factor beta (TGF-beta)/Smad signaling has been implicated in the primary pathogenesis of renal fibrosis. The ubiquitin-proteasome pathway has an important influence on TGF-beta signaling through regulating Smad degradation. As E3 ubiquitin ligases, both Arkadia and Sm...

journal_title：American journal of nephrology

authors： Liu FY,Li XZ,Peng YM,Liu H,Liu YH

更新日期：2007-01-01 00:00:00

abstract：:Several medical inventors in Europe and North America brought the artificial kidney (hemodialysis) to practical usefulness in the late 1940s, but there were very few early successes. It was used at first for only desperate cases of acute renal failure. Renal authorities in the 'metabolic' tradition favored newly quant...

journal_title：American journal of nephrology

authors： Peitzman SJ

更新日期：1997-01-01 00:00:00

abstract：:A multicentre trial (11 nephrology centres) was carried out to test the effects of ibopamine, an orally active dopamine-like drug, on the progression of chronic renal failure. For a 2-year period 189 chronic renal failure patients (serum creatinine level 1.5-4.0 mg/dl) were observed. They were homogeneous for basic ne...

journal_title：American journal of nephrology

authors： Stefoni S,Mosconi G,La Manna G,Bonomini V,Mioli V,Fanciulli E,Feletti C,Docci D,Cappelli P,Bonomini M,Locatelli F,Marai P,Bazzato G,Fracasso A,Brancaccio D,Galmozzi C,Scarpioni L,Sverzellati E,Sorba GB,Cossu M,Pic

更新日期：1996-01-01 00:00:00

abstract：AIMS:This study investigated the protective effect of the angiotensin-converting enzyme inhibitor, enalapril, and the vitamin D analog, paricalcitol, alone or in combination, on cardiac oxidative stress in uremic rats. METHODS:Rats were made uremic by 5/6 nephrectomy and treated for 4 months as follows: (1) uremic + v...

journal_title：American journal of nephrology

authors： Husain K,Ferder L,Mizobuchi M,Finch J,Slatopolsky E

更新日期：2009-01-01 00:00:00