Abstract:
CONCLUSION:PET-CT scans seem to be sufficient to rule out residual tumour at the primary site. Patients with positive or equivocal PET findings should be scheduled for endoscopy with biopsy or a second PET-CT scan. OBJECTIVES:Assessment of remission at the primary site, in patients treated with organ preservation therapy with curative intent, is important to identify residual tumours requiring treatment with salvage surgery. The aim of this study was to evaluate the diagnostic accuracy of fluorodeoxyglucose positron emission tomography (FDG-PET) after radiotherapy with or without chemotherapy in assessing primary site response in patients with head and neck cancer. METHODS:A total of 82 patients, with a positive baseline PET-CT scan before start of treatment, were evaluated with a PET-CT scan 6-7 weeks post-radiotherapy and with a clinical examination/endoscopy with or without biopsy 1-2 weeks later. The majority of patients had p16-positive oropharyngeal tumours. RESULTS:Post-treatment, 77% of the patients had no visible hypermetabolism. If equivocal PET scans are regarded as positive, the sensitivity, specificity, negative (NPV) and positive predictive value (PPV) and accuracy were 100%, 78%, 100%, 6% and 78%, respectively. Eight patients suffered from relapses involving the primary site during the 9-month follow-up.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Sjövall J,Brun E,Almquist H,Kjellén E,Wahlberg Pdoi
10.3109/00016489.2014.895038subject
Has Abstractpub_date
2014-06-01 00:00:00pages
646-51issue
6eissn
0001-6489issn
1651-2251journal_volume
134pub_type
杂志文章abstract::Ionic mechanisms sustaining sensory transduction in crista ampullaris sensory cells have been investigated chiefly by replacing the endolymph with solutions with K+ and Ca++ chelators added. The effects of the modified solutions were evaluated by extracellular and intracellular recordings of both and the presynaptic a...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130893
更新日期:1982-05-01 00:00:00
abstract::The treatment of acute otitis media was studied in 158 children. All children (mean age 4 years) received penicillin orally 80 000--100 000 IU per day for 10 days. Myringotomy was performed on 68 children at the time of the diagnosis. The other 90 children were treated with penicillin and ear drops. The bacteriologica...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909137149
更新日期:1979-01-01 00:00:00
abstract::The early development of human otoconial membranes was studied by scanning electron microscopy and X-ray microanalysis; 87 specimens, ranging from 7 to 12 weeks gestational age were examined. A few otoconia, which contained calcium, were present in the utricle by the end of the seventh week. By 8 weeks, both the saccu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128884
更新日期:1982-07-01 00:00:00
abstract::The purpose of this study was to establish whether lactoferrin (hLf) attached to Streptococcus pyogenes, one causative agent of acute pharyngotonsillitis (AT), during the course of the disease. Bacterial samples were obtained from the tonsillar surfaces of 7 patients (6 females, 1 male; median age 26 years; range 16-5...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::A retrospective study was carried out on repeated audio-vestibular examinations in 53 patients with unilateral Meniere's disease, between the vertiginous spells. Most patients showed no change in the caloric response reduction of the afflicted ear in the subsequent tests compared with the first one. These patients had...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109133278
更新日期:1981-11-01 00:00:00
abstract::To investigate whether the crossed olivo-cochlear bundle (COCB) functions in a protective manner, albino guinea pigs were exposed to sounds of varying intensity (110-130 dB SPL, 3-30 min) with or without electric stimulation of COCB, and the threshold shifts of the compound action potential (CAP) were examined. A stat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665405
更新日期:1992-01-01 00:00:00
abstract:CONCLUSION:The incidence of new cases of Meniere's disease (MD) in elderly patients aged 60 years or more was found to have increased over time after correction for age distribution in the overall population. Job- and care-related fatigue may be involved in the recent increase in elderly-onset cases because physical an...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016480802112587
更新日期:2009-02-01 00:00:00
abstract::Cell proliferation in the endolymphatic sac (ES) after immunostimulation was assessed immunohistochemically. Guinea pigs were employed as experimental animals and keyhole limpet hemocyanin was used as the antigen. After i.p. injection of 5-bromo-2'-deoxyuridine (BrdUrd), the BrdUrd+ cells were counted to assess the nu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139336
更新日期:1995-05-01 00:00:00
abstract:CONCLUSIONS:Subtotal facial nerve decompression seems effective to prevent further episodes of facial palsy and promote facial nerve recovery for recurrent facial palsy in Melkersson Rosenthal syndrome (MRS). The main inflammatory sites of recurrent facial palsy in MRS may be the mastoid segment, tympanic segment, geni...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.863431
更新日期:2014-04-01 00:00:00
abstract::An impaired ostial function may be of importance in the pathogenesis of the maxillary sinus empyema due to changes of the antral gas composition. Oxygen is usually not demonstrable in purulent sinus secretion while carbon dioxide accumulates. In vitro, pneumococci were able to create a similar gas environment, provide...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809121431
更新日期:1978-01-01 00:00:00
abstract::In 4 cases of Meniere's disease, E.P., concentrations of Na, K, Cl, and protein, and osmolality were determined in endolymph from the basal coil of the cochlea. In 3 cases, endolymph was found normal in nature as compared with normal animals. In one long-standing (11 years) case, a strial dysfunction was evidenced. In...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132935
更新日期:1984-05-01 00:00:00
abstract:CONCLUSION:The outcomes of extended subtotal facial nerve decompression via the transmastoid approach were good for facial palsy after temporal bone fracture (TBF). Surgical decompression should be carried out as soon as possible within 8 weeks after trauma. OBJECTIVE:To present outcomes of facial palsy after TBF via ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.981287
更新日期:2015-03-01 00:00:00
abstract::The input from fore- and hindlimbs to the vestibular nuclear complex (VNC) was investigated in awake cats. Electrical stimulus was given to the sciatic, radial and vestibular nerves bilaterally and single unit responses were recorded in the VNC with extracellular technique. The position of the microelectrode was histo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126395
更新日期:1979-01-01 00:00:00
abstract::We report the case of a young male patient with ankylosing spondylitis treated with sulphasalazine who developed bilateral sensorineural hearing loss with tinnitus. Discontinuation of sulphasalazine led to complete resolution of tinnitus and an improvement in hearing loss. We discuss the features of this case and also...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/00016480510026962
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Efficacy of current treatment methods in idiopathic sudden sensorineural hearing loss (ISSNHL) is still unsatisfactory. OBJECTIVE:This study aimed to discover in differences in effect between steroid applications responsible for promoting the prognosis in ISSNHL. MATERIALS AND METHODS:A study was conducted...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1504170
更新日期:2018-11-01 00:00:00
abstract:CONCLUSION:Mouse embryonic stem cells (ESCs) transplanted into the scala tympani are able to migrate in the cochlea of rats deafened with aminoglycoside and partly restore the structure of sensory epithelia of the inner ear. OBJECTIVES:To explore the migration and differentiation of enhanced green fluorescence protein...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.720029
更新日期:2013-02-01 00:00:00
abstract::Fifteen normal speakers (7 women and 8 men), ranging in age from 21 to 35 years, were examined consecutively with rigid telescopy and flexible fiberscopy during sustained phonation at 3 loudness levels. The endoscopes were connected to a stroboscope and video equipment. The purpose was to investigate whether the two l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209100796
更新日期:1992-01-01 00:00:00
abstract::Background: Betahistine is used worldwide to treat patients with Menière's disease. However, despite it being used for decades, diverging opinions on the effect of betahistine on Menière's symptomatology still exist.Aims: The objective of this systematic review was to provide an overview and rate the certainty of the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1777326
更新日期:2020-10-01 00:00:00
abstract:CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480802642096
更新日期:2009-11-01 00:00:00
abstract:CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1170878
更新日期:2016-09-01 00:00:00
abstract::Utilizing an enlarged middle cranial fossa approach to the cerebello-pontine angle without destruction of the labyrinth or cochlea the authors have since 1981 operated on 263 unilateral acoustic neurinomas. Tumour sizes ranged between 3 mm intrameatal and 35 mm within the cerebello-pontine angle. Complete tumour remov...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137419
更新日期:1992-01-01 00:00:00
abstract::The objective of this study was to determine whether methylcobalamin inhibits the ototoxic action of gentamicin. Fourteen pigmented guinea pigs were randomly divided into experimental and control groups. Each animal in the experimental group was given a large single dose of gentamicin (125 mg/kg i.m.), followed by imm...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300102752
更新日期:2001-04-01 00:00:00
abstract::Angioneurotic edema is a non-pitting edema which is usually limited to the skin and the mucous membranes of the face and upper aerodigestive tract. The risk of acute upper airway obstruction makes angioneurotic edema a concern for emergency room physicians, internists and otolaryngologists because prompt recognition o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310005129
更新日期:2003-10-01 00:00:00
abstract:CONCLUSION:Our numerical simulation model provides an accurate reflection of nasal airflow, and the results were validated by clinical measurements. OBJECTIVES:To evaluate the accuracy of a numerical simulation model of nasal airflow. METHODS:Ten volunteers with normal nasal cavities underwent CT, acoustic rhinometry...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.863430
更新日期:2014-05-01 00:00:00
abstract::Many techniques have been proposed for reconstruction of the posterior canal wall and/or obliteration of the mastoid bowl after radical mastoidectomy. The variety of materials that have been used, biological as well as foreign materials of different kinds, indicates that the ideal solution has yet to be found. Plaster...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809122254
更新日期:1988-11-01 00:00:00
abstract::Frozen tissue sections of biopsies from head and neck squamous cancer lesions were examined for immunohistochemical staining with a recently developed monoclonal antibody, designated as SQM1 antibody and directed against the surface membrane of squamous carcinoma cells. SQM1 antibody stained selectively squamous carci...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108684
更新日期:1986-09-01 00:00:00
abstract::Negative membrane potentials from the stria vascularis of the guinea pig have been recorded in vivo. Stable negative membrane potentials from the stria cells have also been recorded for as long as 2 minutes in vitro. They varied from -20 mV to -49 mV, irrespective of whether the stria vascularis was immersed in Ring...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909137159
更新日期:1979-01-01 00:00:00
abstract::Ultrastructural changes of the extrasensory epithelium in the scala media of guinea pig cochleae were observed from 3 to 137 days after perilymphatic perfusion with 20% streptomycin. The degeneration started in the organ of Corti, progressed to the interdental cells and roots of the outer sulcus cells and finally invo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809107516
更新日期:1978-11-01 00:00:00
abstract::Background: The various pathological types of non-squamous cell carcinomas (nSCCs) of the larynx accounted for about 5% laryngeal malignancies, but the knowledge regarding these pathological behaviors, therapeutic models and prognostic factors was limited.Objectives: To investigate the clinical characteristics and the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1700305
更新日期:2020-02-01 00:00:00
abstract::Endoscopy is needed for reliable evaluation of the treatment of nasal polyposis. In this study, we compared the reproducibility of various score systems for staging nasal polyposis and the inter-individual variations between investigators. The mass of the polyps was assessed by five methods, three new techniques (numb...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800760370873
更新日期:2000-01-01 00:00:00