Abstract:
:The solution-scattering profiles of macromolecules are significantly affected by the thermal motions of their atoms, especially at wide scattering angles, even when only a single conformational state is significantly populated in solution. Here it is shown that the impact thermal motions have on the molecular component of the solution-scattering profile of a single-state macromolecule can be predicted accurately if the variances and covariances of the thermal excursions of its atoms from their average positions are known.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Moore PBdoi
10.1016/j.bpj.2014.02.016subject
Has Abstractpub_date
2014-04-01 00:00:00pages
1489-96issue
7eissn
0006-3495issn
1542-0086pii
S0006-3495(14)00221-5journal_volume
106pub_type
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