Abstract：
:(1) Ten patients (mean age 71) with fully developed central retinal venous occlusion were treated by isovolemic hemodilution over a period of four to six weeks. Hematocrit was lowered in steps to about 30% to improve retinal microcirculation. For two to four days, 500 ml whole blood were exchanged daily for about 250 ml hydroxyethyl starch and 250 ml plasma. The procedure was repeated every five to ten days whenever the hematocrit exceeded 35%. Visual acuity was considered to be improved when the patient could read at least two more lines on the test card. Four to six weeks after starting hemodilution therapy visual acuity had improved in seven patients, deteriorated in one, and was unchanged in two. In the follow-up study six months after treatment visual acuity, as compared to data before treatment, had improved in four patients, deteriorated in two and was unchanged in four. Three patients developed a neovascular glaucoma and had to undergo photocagulation treatment. (2) As expected, hemodilution failed to improve visual acuity in five patients who had had a complete central retinal arterial occlusion for more than four hours. (3) This is the first time that a beneficial effect of isovolemic hemodilution on visual acuity, probably mediated by an improvement in retinal blood flow, has been demonstrated in man. However, only in retinal tissue with at least minimal blood flow (venous but not arterial occlusion) can this method be effective. Except for severe anemia or thrombocytosis there are no absolute contraindications. No adverse side-effects were observed. To prevent neovascularization it is planned to use a combination of hemodilution and photocoagulation.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Wiederholt M,Leonhardt H,Schmid-Schönbein H,Hager Hdoi
10.1055/s-2008-1057628subject
Has Abstractpub_date
1980-01-01 00:00:00pages
157-64issue
2eissn
0023-2165issn
1439-3999journal_volume
177pub_type
杂志文章abstract：BACKGROUND:Ocular pulse amplitude (OPA) is reduced in normal tension glaucoma (NTG) patients when compared to non-glaucomatous, healthy control subjects. This might be related to a vasospastic reaction. The objective of this study was to determine if low OPA in NTG is associated with a vasospastic reaction and its resp...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1035074
更新日期：1997-06-01 00:00:00
abstract：:From the results of 628 operations on strabismus convergens, the individual corrections were related to the achieved reduction of the angle of deviation. The evaluation showed that strabismus operations may be well dosed not only with a view to a general improvement of the squint angle but also as a specific influence...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1975-08-01 00:00:00
abstract：BACKGROUND:In order to obtain artifact-free electro-oculogram recordings the subject's cooperation is necessary. The aim of our study is to evaluate the recording characteristics of short-duration EOG and to compare the effect of mydriasis on electro-oculogram recordings in a cohort of controls. PATIENTS AND METHODS:E...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,随机对照试验
doi：10.1055/s-0034-1396330
更新日期：2015-04-01 00:00:00
abstract：:Hereditary optic nerve disorders are rare. For ophthalmologists, Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are of particular relevance. LHON and ADOA are diseases of the retinal ganglion cells and are caused by mitchochondrial dysfunction. LHON is based on mutations of the ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,评审
doi：10.1055/a-0583-6290
更新日期：2018-06-01 00:00:00
abstract：:Diabetic macular edema (DME) and proliferative retinopathy are common causes for blindness in middle-aged patients. The gold standard for treatment has been laser coagulation. Limitations of this therapy are refractive DME, ischaemic diabetic maculopathy and complications after laser application. The need for a non-de...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,评审
doi：10.1055/s-0029-1245718
更新日期：2010-09-01 00:00:00
abstract：:A 36-years aged woman suffering from migraine used Ergosanol special-suppositories. An edema of the retina with star figure appeared in both eyes with only a few months distance. After putting away that drug visual acuity restituted completely in spite of a partial neuritic atrophy of the optic nerve in the first suff...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：:Light absorption and fluorescence measurements can be used to detect accumulations of small molecules in intraocular lenses (IOLs). It was shown that HEMA IOLs can store and to some extent release a variety of drugs and fluorescein. PMMA and silicone IOLs, however, do not have this characteristic. UV-blocking IOLs abs...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1046447
更新日期：1989-10-01 00:00:00
abstract：PURPOSE:The aim of this study was the evaluation of new algorithms to measure diameter of segments of retinal branch vessels offline in local dependence and independent by observer. Methods 360 flashed fundus images (camera FF 450 ZEISS Germany, Visualis IMEDOS GmbH Weimar/Germany) of 12 eyes of healthy volunteers (10 ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2001-17640
更新日期：2001-09-01 00:00:00
abstract：:In spite of modern optical examination techniques such as sonography, nuclear magnetic resonance tomography (NMR) and x-ray computer tomography up to now the meningioma of the optic nerve sheath still poses a problem in respect of differential diagnosis. This problem is illustrated by two case reports. In both patient...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1045712
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:Strabismus with unilateral elevation in adduction is an upward deviation of the adducting eye of unknown, not necessarily paretic origin. The term "old trochlear palsy" may be erroneous since the hypertropia is not necessarily larger in downward gaze and a causative lesion can usually not be identified. We d...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1035299
更新日期：1996-08-01 00:00:00
abstract：PURPOSE:We report the clinical, morphological, and ultrastructural findings of 13 consecutively explanted opacified Hydroview(R) (hydrogel) intraocular lenses (IOLs). Our purpose was to provide a comprehensive account on the possible factors involved in late postoperative opacification of these IOLs. PATIENTS AND METH...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 临床试验,杂志文章
doi：10.1055/s-0028-1109319
更新日期：2009-04-01 00:00:00
abstract：:Forty eyes were studied in order to establish the relative function of the upper and lower lacrimal ducts. Following artificial occlusion first of the upper and then of the lower lacrimal ducts. Schirmer's No. 1 test was performed. The wetting of the test strips was used as an indirect measure of tear discharge. Highe...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1054425
更新日期：1984-02-01 00:00:00
abstract：:A retinoneuritis due to ethambutol (Myambutol) occurs with Myambutol doses of over 20 mg/kg per day after 3 weeks to 15 months. Visual acuity can deteriorate within the following 6 months even after immediate discontinuation of treatment with Myambutol. It may recover 2 months (though in some cases only 16 months) aft...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1050982
更新日期：1985-07-01 00:00:00
abstract：:A comparative trial was performed on 56 glaucomatous eyes - piladren gave usually a better pressure-reducing effect than pilocarpine alone or pilocarpine and epinephrine/adrenaline from separate bottles. The main possibilites of medical glaucoma therapy are mentioned and subjective and objective advantages and disadva...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 临床试验,杂志文章
doi：
更新日期：1976-10-01 00:00:00
abstract：BACKGROUND:Uveitis is a frequent and potentially vision-threatening manifestation of juvenile idiopathic arthritis (JIA). There are only a few population-based studies providing data on the frequency and severity of uveitis. METHODS:Documentation of patients with JIA was collected in a national database. An analysis o...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2005-858753
更新日期：2005-12-01 00:00:00
abstract：PATIENTS AND METHODS:In 28 patients after perforating keratoplasty followed by epithelial abrasion of the transplant the period required for epithelial closure with a therapy including collagen shields and the growth stimulating factors vitamin A and Epidermal Growth Factor (EGF) was determined. RESULTS:A significant ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2008-1045517
更新日期：1994-10-01 00:00:00
abstract：:A total of 369 ophthalmological practices were asked to report the number of patients seen within one test week who drove their cars but did not satisfy minimum legal requirements for diurnal visual acuity applicable for applicants for a West German Class 3 driver's license. There were 471 such patients. From this num...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1054574
更新日期：1984-08-01 00:00:00
abstract：:The conjunctivae of nine rabbits of the same breed were used to compare the local compatibility of the Endorfer Jod-Thermalsole with that of a physiological NaCl solution. The neuroleptanalgesics were administered using perfusion techniques. The reddening thus caused was used to measure the degree of inflammation. The...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1055295
更新日期：1981-01-01 00:00:00
abstract：:We document a case of unilateral hemiarcus lipoides, which developed de novo 10 months after trabeculectomy in the left eye of a 54-year-old woman. The involved eye showed heterochromia complicata Fuchs and had undergone intracapsular cataract extraction 11 years and trabeculectomy one year earlier. Except for intermi...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1046289
更新日期：1990-10-01 00:00:00
abstract：:As a result of an acute pathologic event ophthalmic arterial pressure may fall below a level necessary to supply sufficient blood to the eye and optic nerve, and thus to preserve full visual function. A sudden partial or even total loss of visual function. A sudden partial or even total loss of vision may follow. In s...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057432
更新日期：1980-02-01 00:00:00
abstract：:Anti-VEGF injections are widely used "off-label" for the treatment of choroidal neovascularization secondary to pathological myopia based on data generated by multiple case series with small sample sizes. In this review we have analyzed the results of case series with at least 20 patients and a follow-up of ≥ 12 month...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,meta分析,评审
doi：10.1055/s-0034-1368289
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:An evaluation of the visual and refractive results was undertaken one year after implantation of a trifocal diffractive toric intraocular lens (IOL) during cataract surgery. METHODS:In a prospective study patients with a calculated postoperative corneal astigmatism of ≥ 0.75 D received a diffractive trifocal t...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 临床试验,杂志文章
doi：10.1055/s-0041-103335
更新日期：2015-08-01 00:00:00
abstract：:In addition to ophthalmic symptoms (ptosis and retinitis pigmentosa), our patient displayed symptoms of disturbances of cardial conduction as well a mitochondrial myopathy. The latter was confirmed histologically. The order in which the symptoms of the disease appear may vary, but the close cooperation of ophthalmolog...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1045466
更新日期：1994-05-01 00:00:00
abstract：BACKGROUND:The use of virtual reality (VR) has gained increasing interest for the acquirement of ophthalmosurgical skills outside the operating room and is thereby increasing patients' safety. The aim of this study was to evaluate trainees' acceptance of VR for assessment and training during several Drylabs with an oph...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0028-1109383
更新日期：2009-08-01 00:00:00
abstract：:In a 49-year-old patient bilateral papilloedema with an empty sella turcica was observed. A summary of the literature references to this syndrome and its pathogenesis and its eye complications are given and discussed. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1978-04-01 00:00:00
abstract：:The position of the ophthalmologist as an unbiased and impartial expert in the field of tension between the client and the patient is a responsible task that should not be underestimated. Since the ophthalmological expert assessment often has far-reaching legal and financial consequences, it is very important that it ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/a-0889-9523
更新日期：2019-04-18 00:00:00
abstract：BACKGROUND:In spite of the worldwide declining number of syphilis cases, there has been stable rate of syphilis infections in Switzerland from 2006 - 2008. In the year 2008 672 case were reported. Uveitis is the most common ocular finding in syphilis. It occurs in 2.5 %-5 % of all cases. HISTORY AND SIGNS:Six patients...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0031-1273229
更新日期：2011-04-01 00:00:00
abstract：:Case report on a child with acute lymphogenous leukemia. Although there was constant hematological remission she developed an isolated leukemic iritis and secondary glaucoma. The clinical picture showed a characteristic stratification of the hyphema. After the patient had remained seated for a prolonged period of time...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1050208
更新日期：1988-06-01 00:00:00
abstract：:Corneal topographs that measure the anterior and posterior corneal surface with optical methods need a clear cornea for precise measurements. Opacities cause artifacts in the corneal thickness (with measurements usually being too thin) and corneal curvatures. This is important to know as certain pathologies may repeat...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0032-1327956
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:The gold standard therapy for full-thickness macular holes (FTMH) is vitrectomy (PPV) with peeling of the internal limiting membrane (ILM), gas tamponade of the vitreous cavity and postoperative face-down positioning. Nevertheless, eyes with large macular holes (> 400 µm) and surgical failures remain difficu...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0043-121032
更新日期：2018-10-01 00:00:00
