[Effect of corneal collagen shields and epithelial growth promoting factors on epithelialization of the human cornea].

Abstract:

PATIENTS AND METHODS:In 28 patients after perforating keratoplasty followed by epithelial abrasion of the transplant the period required for epithelial closure with a therapy including collagen shields and the growth stimulating factors vitamin A and Epidermal Growth Factor (EGF) was determined. RESULTS:A significant acceleration of the epithelialization was observed in all groups treated with collagen shields compared to the control group. There is no significant difference between collagen shield application without additives and a therapy with collagen and EGF. Under collagen and retinyl palmitate therapy the epithelialization compared to collagen without additives as well as compared to collagen and EGF at a concentration of 100 ng/ml is significantly accelerated (p = 0.05). CONCLUSION:Collagen shields, especially combined with vitamin A and EGF, can be employed as a therapeutic concept offering accelerated epithelial wound closure after keratoplasty.

journal_name

Klin Monbl Augenheilkd

authors

Kammann JP,Vollenberg C

doi

10.1055/s-2008-1045517

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

201-9

issue

4

eissn

0023-2165

issn

1439-3999

journal_volume

205

pub_type

临床试验,杂志文章,随机对照试验
  • [Corneal endothelial damage in congenital and juvenile glaucoma].

    abstract::Corneal changes are typical for infantile glaucoma. In newborns, Descemet's membrane and the stroma are still soft, and distend when intraocular pressure rises. Cell counts were performed under the reflecting microscope to determine whether the endothelium is affected when corneal diameter increases and changes occur ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050052

    authors: Wenzel M,Krippendorff U,Hunold W,Reim M

    更新日期:1989-12-01 00:00:00

  • [Pseudoexfoliation syndrome].

    abstract::The Frequency of the Pseudoexfoliation-Syndrom (= PES) was investigated about two months in a prospective study of 1069 patients in the university eye hospital of Zurich. 7.35% of these patients had a PES with or without glaucoma. Among the clinic patients there were 9.9% and among the policlinic patients 6.26%. All o...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045974

    authors: Esmail F

    更新日期:1991-05-01 00:00:00

  • [Treatment of therapy resistant congenital postsaccular lacrimal duct stenosis with the flexible indwelling catheter].

    abstract::A flexible silicone-rubber suturamide retention tube, the procedure of intubation and special instruments for the repair of persistent congenital nasolacrimal duct obstructions are described. The results of the treatment of 8 infants are discussed. With the exception of one functional failure, the very good results ar...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054617

    authors: Struck HG,Fikentscher R

    更新日期:1984-10-01 00:00:00

  • [Survival after treatment for malignant choroidal melanoma: comparison between conservative therapy (Ru106/Rh106 applicator) and enucleation with and without postoperative irradiation to the orbit; 1960 to 1979].

    abstract::The survival rate was calculated using the life table method in 1,501 patients suffering from choroidal melanomas and treated in 10 eye hospitals in the GDR between 1960 and 1979. The results of treatment by (1) enucleation, (2) enucleation with postoperative irradiation of the orbit and (3) local irradiation with 106...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054399

    authors: Kiehl H,Kirsch I,Lommatzsch P

    更新日期:1984-01-01 00:00:00

  • [Autophagy in visual cell renewal processes (author's transl)].

    abstract::The biological significance of autophagy in the metabolism of visual cells is discussed. In the process of autophagy, parts of the cytoplasm including cell organelles are surrounded by membranes. This formation is called an autophagic vacuole. Then, the contents of the vacuole are degraded by enzymes. Autophagy is a w...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Remé CE

    更新日期:1978-09-01 00:00:00

  • [Echographic findings in choroidal detachment].

    abstract::A- and B-scan sonography was performed in 83 patients with choroidal detachment; a serous choroidal detachment is characterized by high, bifurcated echospikes and an echo-free subchoroidal space in A-scan sonography. The B-scan presents a typical arc shape. In hemorrhagic choroidal detachment multiple echoes with low ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054708

    authors: Rochels R,Hackelbusch R

    更新日期:1983-01-01 00:00:00

  • [Long-term follow-up of 700 trabeculectomies].

    abstract:BACKGROUND:A major focus of our study was to determine the value of postoperative intraocular pressure (IOP) in predicting the outcome of trabeculectomy (TE). PATIENTS AND METHODS:The medical charts of 547 patients undergoing glaucoma filtering surgery at the Department of Ophthalmology of the University of Cologne fr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2000-10376

    authors: Khalili MA,Diestelhorst M,Krieglstein GK

    更新日期:2000-07-01 00:00:00

  • [Iridocyclectomy with scleral flap].

    abstract::In this paper the author describes a modification of iridocyclectomy. Before opening the bulbus and removing the malignant melanoma, a lamellar scleral flap is formed with its base at the limbus. After extirpation of the tumor the area is "plastically" covered with this flap. This modification was used on 5 patients; ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Oláh Z

    更新日期:1983-12-01 00:00:00

  • [Catalase activity in argon-laser irradiation].

    abstract::Catalase may provide protection against photochemical action of superoxide radicals and hydrogen peroxide. The authors tried to measure its activity in freshly enucleated calf eyes before and after argon laser irradiation. It was established by iodometric titration that catalase activity was reduced after irradiation ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050720

    authors: Wolf S,Mayer UM

    更新日期:1986-06-01 00:00:00

  • [Clinical problems of different forms of heterochromie(author's transl)].

    abstract::The causes of hypo- and hyperchromic heterochromia were analysed in 94 patients. The hypochromic forms were the commonest, especially the Fuchs-Herrenschwandt heterochromia, and heterochromia simplex. Also after degenerative diseases and accidents appears almost exclusively hypochromic heterochromia. Causes of hyperch...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Pietruschka G,Priess G

    更新日期:1975-04-01 00:00:00

  • [Familial cataract in plasma galactitol increase without known enzyme defect].

    abstract:BACKGROUND:Several enzyme defects of the galactose pathway may lead to cataract formation. We report on a family with familiar cataract. PATIENTS:A 2-year-old Turkish girl (daughter of first cousins) presented with dense cortical and subcapsular opacifications and mature cataract respectively. Bilateral phacectomy, pl...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034710

    authors: Budde M,Gusek-Schneider GC,Jünemann A,Jansen F,Shin YS

    更新日期:1999-10-01 00:00:00

  • [Intraocular inflammations. Anamnesis and clinical study].

    abstract::Extensive laboratory work-ups are often called for to establish the diagnosis in uveitis cases. In order to interpret the results, however, the degree of validity of the tests must be known. As the number of laboratory tests increases there is a considerable increase in the probability of false-positive results. Demog...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1046387

    authors: Messerli J

    更新日期:1989-05-01 00:00:00

  • [A convex-concave contact lens for vitreoretinal operations with the BIOM].

    abstract::A new convex-concave contact lens for wide-angle vitreoretinal surgery with the BIOM was developed. Placed on an eye, in which silicone oil is injected, it prevents the formation of an optically disturbing oil-water-film on the surface of the cornea. Thus the new contact lens leads to an essential improvement of the f...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045932

    authors: Eckardt C,Wiechens B

    更新日期:1991-01-01 00:00:00

  • [Clinical findings in phakolytic glaucoma (author's transl)].

    abstract::1300 enucleated globes were examined from 1966-1974: Among these 20 eyes (1.5%) revealed a "phacolytic glaucoma" histologically. The clinical diagnosis before enucleation were "secondary glaucoma" or "absolute glaucoma" (19) and once "uveitis dolorosa". "Phakolysis" was considered in only 3 eyes. 15 cases revealed sur...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Völcker HE,Naumann G

    更新日期:1975-05-01 00:00:00

  • Follicular conjunctivitis caused by a mantle cell lymphoma.

    abstract:BACKGROUND:Lymphoma of the conjunctiva as part of a systemic disease is rare. The follicular appearance of the lymphocyte hyperplasia may mimic the clinical picture of infectious or allergic conjunctivitis. We report on a case of marked chronic follicular conjunctivitis, finally diagnosed as mantle cell lymphoma. HIST...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2004-812865

    authors: Amstutz CA,Michel S,Thiel MA

    更新日期:2004-05-01 00:00:00

  • [Actinomycetes granuloma of the upper eyelid].

    abstract::An African 40-year-old woman presented with a superior eyelid tumor. The diagnosis is a granuloma due to Actinomycetae. We briefly describe the pathogenesis, and the ancillary diagnostic methods. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035071

    authors: Tritten JJ,Uffer S

    更新日期:1997-05-01 00:00:00

  • [The usefulness of echography in retinal surgery (author's transl)].

    abstract::Upon utilization of echography one certainly will not be able to detect retinal defects; however, other parameters of retinal detachment which by means of solely optical examination techniques may remain undiagnosed can be evaluated successfully. This concerns not only the diagnosis of retinal detachment alone but als...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Freyler H

    更新日期:1979-03-01 00:00:00

  • [Corneal endothelial cell density following strabismus surgery].

    abstract:BACKGROUND:The short-term impact of eye muscle surgery on the blood-aqueous barrier has been described by iris fluoresceinangiography and laser tyndallometry. The aim of this study was to investigate the long-term effects of eye muscle surgery on the oxygen supply of the anterior segment of the eye by determination of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-962981

    authors: Gusek-Schneider GC,Kamoun R,Klaas D,Seitz B

    更新日期:2007-03-01 00:00:00

  • [Intrabulbar and peribulbar reactive lymphoid hyperplasia].

    abstract::Report on a 69-year-old woman with a choroidal and a large peribulbar tumor. A scan ultrasonography of the peribulbar mass revealed a homogeneous structure of the lymphoma/sarcoma/pseudo-tumor type. Histological examination disclosed a reactive lymphoid hyperplasia without "Dutcher bodies", and consistent with a benig...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057457

    authors: Haddad R,Slezak H,Till P

    更新日期:1980-02-01 00:00:00

  • [Hema socket expander in primary conservative treatment of congenital anophthalmos].

    abstract::In anophthalmos the forces which stimulate development and growth of the bony orbit are absent. As a result these cases have not only a tiny socket but also an underdeveloped bony orbit, which cannot retain an artificial eye. The small conjunctival sac and bony orbit can be mechanically enlarged by means of Hema socke...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050502

    authors: Steinkogler FJ,Polzhofer K

    更新日期:1987-09-01 00:00:00

  • [Lysosomal storage diseases - update and new therapeutic options].

    abstract::Lysosomal storage diseases represent a group of about 50 genetic disorders. The deficiencies of lysosomal and non-lysosomal proteins cause an accumulation of compounds which are normally degraded within the lysosome. There are currently no therapeutic options to cure patients suffering from a lysosomal storage disease...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0028-1109958

    authors: Schöpfer K,Miebach E,Beck M,Pitz S

    更新日期:2011-02-01 00:00:00

  • [Special sound probe for foreign body localisation (author's transl)].

    abstract::A recently developed sound probe (10 MHz and 3 mm diameter) is suitable for sparing preoperative localisation of foreign bodies in perforated eyes; especially mural foreign bodies can be exactly located intraoperatively. Followed scleral incision foreign bodies can be extracted on the optimal route. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Till P

    更新日期:1978-02-01 00:00:00

  • [Spontaneous regression of diabetic retinopathy (author's transl)].

    abstract::A report is given on seventeen cases of spontaneous regression of diabetic retinopathy. The diabetes became manifest, without exception, at an early age, particularly in childhood. Regression came on slowly and inconspicuously, retinopathy disappearing completely in two thirds of the cases. Of the other forms of diabe...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Fischer F

    更新日期:1976-11-01 00:00:00

  • [Long-acting local anesthetics - an enrichment in ophthalmosurgery? (author's transl)].

    abstract::In 300 cases the effectiveness of the long-acting anesthetic Meaverin-ultra for retrobulbar anesthesia was systematically investigated. The duration of analgesis and immobilisation for the globe as well as for the eyelids runs over hours; they are considerabley more effective than with other common local anesthetics s...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Schlegel HJ

    更新日期:1977-09-01 00:00:00

  • [Glaucoma without ocular hypertension. A clinical study].

    abstract::One hundred eighty-four glaucomatous eyes (125 patients) with visual field defects of Stage I and II in the central visual field were examined with the Octopus perimeter 201, Program 31 or 33, and were divided into 3 groups according to maximum intraocular pressures: (1) low-tension glaucoma (21 mm Hg), (2) glaucoma s...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050918

    authors: Gramer E,Leydhecker W

    更新日期:1985-04-01 00:00:00

  • [Can the cutting performance of trephines still be improved?].

    abstract:PURPOSE:Today, for the preparation of donor and recipient cornea during keratoplasty either single-use or reusable metal trephines are commonly used although excimer and femtosecond laser systems are available. Due to the surgical techniques as well as the configuration of metal trephine's cutting edge irregular cornea...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858661

    authors: Lingenfelder C,Kupferschmid S,Grabowy U,Kleinen L,Spraul CW

    更新日期:2005-09-01 00:00:00

  • [Pseudoexfoliation syndrome in patients with retinal vein branch and central vein thrombosis].

    abstract:BACKGROUND:Pseudoexfoliation syndrome is a frequent cause of secondary open-angle glaucoma due to deposition and in situ-production of abnormal extracellular matrix proteins in the trabecular meshwork. Glaucomas itself are a known risk factor for retinal vein thrombosis. In this retrospective study the prevalence of ps...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035088

    authors: Cursiefen C,Händel A,Schönherr U,Naumann GO

    更新日期:1997-07-01 00:00:00

  • [Foveal cone dystrophy: diagnostic ranking of the multifocal electroretinogram].

    abstract:BACKGROUND:In case of visual loss without morphologic pathology differentiation between a functional visual loss and a retinal disorder may be difficult. PATIENTS AND METHODS:We report on two women, aged 33 and 44, who were complaining of a progressive visual loss occurring over the past several weeks to months. They ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-32633

    authors: Hübsch S,Gräf M

    更新日期:2002-05-01 00:00:00

  • [Optimised frontal suspension for correction of complicated ptosis].

    abstract::Complicated ptosis can be corrected by frontal suspension with autologous fascia lata. Via an open approach, the fascia is implanted between the brow and the tarsal plate behind the septum. The oblique implantation between the tarsus and the brow preserves the flexibility of elevation, closure and blinking of the uppe...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1281848

    authors: Pfeiffer MJ

    更新日期:2012-01-01 00:00:00

  • [Histology and therapy of diabetic traction detachment].

    abstract::Diabetic tractional detachment of the retina is caused by shrinking processes of the vitreous, which at most detaches only partially, and by shrinking of epiretinal proliferations. The shrinking of the vitreous results in tractional forces working centripetally and toward the base of the vitreous. The shrinking of the...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054438

    authors: Faulborn J

    更新日期:1984-03-01 00:00:00