[Myambutol (ethambutol)-induced retinoneuritis].

Abstract:

:A retinoneuritis due to ethambutol (Myambutol) occurs with Myambutol doses of over 20 mg/kg per day after 3 weeks to 15 months. Visual acuity can deteriorate within the following 6 months even after immediate discontinuation of treatment with Myambutol. It may recover 2 months (though in some cases only 16 months) after the onset of the deterioration; in cases of optic atrophy a more severe loss of vision usually remains. If there was loss of vision to 1/10 or less there was in most cases no change in the visual acuity. On the other hand, a primary loss of vision to only 0.3 or 0.4 usually ended with recovery of full vision. The occasionally observed clinical picture of a reddish optic disk, retinal hemorrhages, a very fine granular pigment alteration of the macular region, and loss of vision for more than a year without optic disk pallor suggests a toxic retinitis or retinoneuritis rather than neuritis. This is confirmed by electrophysiological observations.

journal_name

Klin Monbl Augenheilkd

authors

Pau H

doi

10.1055/s-2008-1050982

subject

Has Abstract

pub_date

1985-07-01 00:00:00

pages

25-9

issue

1

eissn

0023-2165

issn

1439-3999

journal_volume

187

pub_type

杂志文章
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    更新日期:2007-06-01 00:00:00

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    authors: Schnaudigel OE

    更新日期:1981-12-01 00:00:00

  • [Autoregulation in ischemia of the optic nerve in the human].

    abstract:BACKGROUND:Autoregulation is defined as the maintenance of constant blood flow in a vascular system in spite of changes in perfusion pressure (PPm). MATERIALS AND METHODS:PPm was decreased by increasing the intraocular pressure (IOP) with a suction cup and optic nerve blood flow was measured with the laser Doppler flo...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Titzé P,Hero M,Petrig BL,Cranstoun SD,Riva CE

    更新日期:1997-05-01 00:00:00

  • [Optimization of irradiation time in the treatment of malignant melanoma of the choroid with beta applicators (106Ru/106Rh)].

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    authors: Lommatzsch PK,Weise B,Ballin R

    更新日期:1986-08-01 00:00:00

  • [Indications for Retinal Laser Therapy Revisited].

    abstract:BACKGROUND:Laser therapy is an important treatment option in retinal diseases, especially in cases of vascular involvement. Most approaches are based on coagulation of retinal structures. As there is increasing use of agents targetting vascular endothelial growth factor in the treatment of macular diseases, indications...

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    authors: Enders P,Schaub F,Fauser S

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  • [Greek anatomy of the eye in Pakistan today].

    abstract::A Pakistani wall plate depicting the anatomy of the eye is described and illustrated. The picture is partly Greek (the hollow optic nerve), in part medieval Arab (the optical image on the disk), and in part modern (e.g., the refraction anomalies). A brief account is given of how Greek science passed to the Arabs and t...

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    pub_type: 历史文章,杂志文章

    doi:10.1055/s-2008-1050281

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    更新日期:1988-10-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Benedikt O

    更新日期:1977-01-01 00:00:00

  • [Lens changes following pneumatic retinopexy: preliminary results of linear densitometry image analysis of Scheimpflug photographs two months after operation].

    abstract::The small degree of morbidity and a better postoperative visual acuity are the advantages of pneumatic retinopexy in comparison to encircling procedures in the treatment of retinal detachment. The injection of air or gas into the vitreous cavity can theoretically induce a cataract postoperatively. Two months after pne...

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    authors: Koch F,Hockwin O,Böker T,Mougharbel M

    更新日期:1991-06-01 00:00:00

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    authors: Wildberger H,Niemeyer G,Junghardt A

    更新日期:2003-03-01 00:00:00

  • [Zinc concentration in the aqueous humor (author's transl)].

    abstract::The zinc concentration in normal human aqueous humor was determined with the help of an atomic absorption spectrophotometer. The mean value was 0.359 ppm with a scatter range of 0.27 to 0.44 ppm. The spectrophotometer permits simultaneous determination of two metals, in this case zinc and copper. It was possible to de...

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    doi:10.1055/s-2008-1057525

    authors: Gerhard JP,Calmé P,Kraeminger E

    更新日期:1980-04-01 00:00:00

  • [Impact of cataract surgery on intraocular pressure after filtering operation due to primary open angle glaucoma and secondary glaucoma in pseudoexfoliation syndrome].

    abstract:PURPOSE:To analyse the impact of cataract surgery after filtering operation on the intraocular pressure (IOP) due to primary open angle glaucoma (pOAG) versus secondary open angle glaucoma in pseudoexfoliation syndrome (PEX). The regulation of IOP was evaluated on the basis of criteria of advanced glaucoma intervention...

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    authors: Wakili N,Seitz B,Hayler J,Händel A,Jünemann A

    更新日期:2002-03-01 00:00:00

  • [Acute reversible night blindness caused by vitamin A deficiency in pancreatic carcinoma].

    abstract:BACKGROUND:Vitamin A deficiency is a leading cause of blindness in childhood in the developing countries. In developed countries xerophthalmia occurs mainly as secondary hypovitaminosis due to malabsorption in chronic alcoholism or intestinal disorders. PATIENT AND METHODS:A 24-year-old female patient complained of ni...

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    doi:10.1055/s-2008-1034956

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    更新日期:1998-08-01 00:00:00

  • [Hemorrhagic secondary glaucoma after central venous thrombosis].

    abstract::Patients suffering from neovascular glaucoma who had been treated at the First Vienna University Eye Clinic in the years 1966-1979 were analyzed recently in a retrospective study. The present paper concentrates on 144 cases of hemorrhagic secondary glaucoma after central venous thrombosis. It considers only those pati...

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    更新日期:1983-08-01 00:00:00

  • [Optic Disk Drusen: Historical and Up-To-Date Aspects].

    abstract::Optic disc drusen are an important differential diagnosis in the diagnostic evaluation of a prominent optic nerve head. Drusen of the optic disc occur in 0.34 to 2.4 % of human individuals and manifest themselves bilaterally in three of four cases. Drusen are found six times more often within histological sections tha...

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  • [Tear Film Osmolarity in Normal Individuals: Comparison of Two Osmometers].

    abstract:INTENTION:The hyperosmolarity of the tear film is an important clinical sign of dry eye disease. It is the most important diagnostic parameter. In addition to the TearLab osmometer (TearLab Corp, San Diego, CA), which has been available for several years, the I-Pen osmometer (I-MED Pharma Inc, Dollard-des-Ormeaux, Queb...

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    authors: König S,Priglinger S,Schaumberger M,Messmer EM

    更新日期:2020-05-01 00:00:00

  • [Ocular manifestations of rheumatic diseases. Cooperation between internist/ophthalmologist].

    abstract::A red or painful eye may be the clue to a systemic condition, many of which are of a rheumatological or immunological nature. Conjunctivitis may occur in Sjögren's Syndrome, Reiter's Syndrome (and other sero negative spondyloarthropathies) and with infections such as chlamydia and viruses. 70% of cases of episcleritis...

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    更新日期:1993-05-01 00:00:00

  • [The iridociliary suture (author's transl)].

    abstract::During a trabeculectomy it is possible to interfere with the boundary between the iris and the ciliary body-that is with the iridociliary suture. The author describes some special features of this region which can be recognized through the operating microscope, with allusions to some aspects of optical microscopy. ...

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    doi:

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    更新日期:1977-12-01 00:00:00

  • [Congenital fibrosis syndrome. Considerations on etiology, genetics and surgical therapy].

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    更新日期:1990-08-01 00:00:00

  • [Efficacy of a Dexamethasone Implant for the Treatment of Refractory Cystoid Macular Oedema in Non-Infectious Uveitis].

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    更新日期:2016-05-01 00:00:00

  • [Endothelial Cell Reaction to Elevated Hydrostatic Pressure and Oxidative Stress in Vitro].

    abstract:INTRODUCTION:Endothelial dysfunction has become a strongly discussed factor regarding glaucoma pathogenesis. In addition to peripapillary bleedings as signs of vascular damage, there is a definite correlation between glaucoma and vascular dysregulation syndrome. The aim of this study was to evaluate endothelial cell re...

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    更新日期:2019-09-01 00:00:00

  • [Simulation of anterior ischemic optic neuropathy by optic nerve sheath meningioma].

    abstract:BACKGROUND:The optic nerve sheath meningioma usually presents with a diffuse atrophy of the disc and a diffuse depression of the visual field. Applying this rule too rigidly can lead to a false diagnosis. PATIENT:A 45y-old-woman presented with atrophy of the upper disc and a corresponding altitudinal field defect in h...

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    doi:10.1055/s-2008-1035368

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    更新日期:1995-09-01 00:00:00

  • [Choroidal Neovascularisation Other than Typical Neovascular Age-Related Macular Degeneration].

    abstract::Choroidal neovascularisation (CNV) in the context of exsudative age-related macular degeneration (nAMD) can be divided into type 1 (occult) and type 2 (classical) membranes. Retinal angiomatous proliferation (RAP) or polypoidal choroidal vasculopathy (PCV) are "rare subtypes" of chorioretinal neovascularisation and ar...

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    更新日期:2018-08-01 00:00:00

  • [Clinical experiences and results of application of mitomycin C in trabeculectomy].

    abstract:BACKGROUND:Mitomycin C (MMC) used as an additive agent in glaucoma surgery has been shown to improve the postoperative results of intraocular pressure (IOP), but may also lead to higher incidences of postoperative wound healing disorders and of hypotonia with choroidal detachment. In this retrospective study the levels...

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    更新日期:2003-09-01 00:00:00

  • [Keratoplasty in Germany: Systematic Analysis of the Quality Reports of German Hospitals between 2006 and 2017].

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