Serum IL-10 involved in morphine tolerance development during adjuvant-induced arthritis.

abstract：:Diabetes is a risk factor for cardiovascular disease that has a multifactorial etiology, with oxidative stress as an important component. Our previous observation of a significant diabetes-related increase in rat cardiac catalase (CAT) activity suggested that CAT could play a major role in delaying the development of ...

journal_title：Journal of physiology and biochemistry

authors： Ivanović-Matić S,Bogojević D,Martinović V,Petrović A,Jovanović-Stojanov S,Poznanović G,Grigorov I

更新日期：2014-12-01 00:00:00

abstract：:The present review aims to illustrate current knowledge about the efficacy of omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) in treating/preventing several metabolic pathologies. We reviewed systematically the published evidence on the effectiveness of n-3 LC-PUFAs fish consumption or n-3 LC-PUFAs suppl...

journal_title：Journal of physiology and biochemistry

authors： Lorente-Cebrián S,Costa AG,Navas-Carretero S,Zabala M,Martínez JA,Moreno-Aliaga MJ

更新日期：2013-09-01 00:00:00

abstract：:Several meta-analyses describing the effect of n-3 polyunsaturated fatty acids on the survival rate of the victims of an acute coronary event do not clearly support a beneficial impact of these fatty acids. Yet, animal studies consistently show n-3 PUFA-induced protection against ischemia-reperfusion-induced myocardia...

journal_title：Journal of physiology and biochemistry

authors： Demaison L,Leger T,Vergely C,Rochette L,Azarnoush K

更新日期：2019-08-01 00:00:00

abstract：:Our previous findings demonstrated that hypothermia enhances the reduction potential in the liver and helps to maintain the plasmatic antioxidant pool. Here, we aimed to elucidate if hypothermia protects against hypoxia-induced oxidative stress damage in rat liver. Several hepatic markers of oxidative stress were comp...

journal_title：Journal of physiology and biochemistry

authors： Garnacho-Castaño MV,Alva N,Sánchez-Nuño S,Bardallo RG,Palomeque J,Carbonell T

更新日期：2016-12-01 00:00:00

abstract：:Adipose tissue has long been considered to be involved in tumor progression. However, the adipocyte-secreted molecular determinants that regulate hepatocellular cancer progression have not been defined yet. In this study, the expression pattern of exosome miRNAs in hepatocellular carcinoma (HCC) patients with high bod...

journal_title：Journal of physiology and biochemistry

authors： Liu Y,Tan J,Ou S,Chen J,Chen L

更新日期：2019-08-01 00:00:00

abstract：:Low shear stress (LSS) occurs in areas where atherosclerosis is prevalent. Many studies have revealed that signal transducer and activator of transcription 1 (STAT1) plays a significant role in cardiovascular disease. Nonetheless, the mechanism underlying the connection between STAT1 and LSS is not fully understood. T...

journal_title：Journal of physiology and biochemistry

authors： Zhu L,Wang F,Yang H,Zhang J,Chen S

更新日期：2020-02-01 00:00:00

abstract：:Hearts from subjects with different ages have different Ca(2+) signaling. Release of Ca(2+) from intracellular stores in response to an action potential initiates cardiac contraction. Both depolarization-stimulated and spontaneous Ca(2+) releases, Ca(2+) transients and Ca(2+) sparks, demonstrate the main events of exc...

journal_title：Journal of physiology and biochemistry

authors： Kandilci HB,Tuncay E,Zeydanli EN,Sozmen NN,Turan B

更新日期：2011-09-01 00:00:00

abstract：:The protective effects of downregulated miR-199a-5p on ischemic and hypoxic cardiomyocytes were well recognized, but the underlying mechanism of inhibited miR-199a-5p is not yet clear. The present study explored the relationship between enhanced signal transducer and activator of transcription 3 (STAT3) signaling and ...

journal_title：Journal of physiology and biochemistry

authors： Zhou Y,Pang B,Xiao Y,Zhou S,He B,Zhang F,Liu W,Peng H,Li P

更新日期：2019-02-01 00:00:00

abstract：:In order to obtain healthier goat milk as far as its fat composition is concerned, milk production and composition trials were carried out with Granadina goats kept in semi-extensive breeding conditions. The animals were feeding indoors with a concentrate supplemented or not with 7% of fat conveniently protected again...

journal_title：Journal of physiology and biochemistry

authors： Sanz Sampelayo MR,Martín Alonso JJ,Morón D,Pérez L,Boza J

更新日期：2000-09-01 00:00:00

abstract：:Growth hormone plays a key role in the maturation and maintenance of the immune response, however, the effects of chronic high circulating concentrations of the hormone on the immune system is poorly understood. Transgenic mice overexpressing bovine growth hormone (b-GH) gene, fused to the rat phosphoenolpyruvate carb...

journal_title：Journal of physiology and biochemistry

authors： Esquifino AI,Arce A,Alvarez MP,Szary A,Brown-Borg H,Bartke A

更新日期：2002-09-01 00:00:00

abstract：:A large number of researches have led to a substantial growth of knowledge about exercise and oxidative stress. Initial investigations reported that physical exercise generates free radical-mediated damages to cells; however, in recent years, studies have shown that regular exercise can upregulate endogenous antioxida...

journal_title：Journal of physiology and biochemistry

authors： Thirupathi A,Pinho RA

更新日期：2018-08-01 00:00:00

abstract：:Epigenetics has an important role in the regulation of metabolic adaptation to environmental modifications. In this sense, the determination of epigenetic changes in non-invasive samples during the development of metabolic diseases could play an important role in the procedures in primary healthcare practice. To help ...

journal_title：Journal of physiology and biochemistry

authors： San-Cristobal R,Navas-Carretero S,Milagro FI,Riezu-Boj JI,Guruceaga E,Celis-Morales C,Livingstone KM,Brennan L,Lovegrove JA,Daniel H,Saris WH,Traczyk I,Manios Y,Gibney ER,Gibney MJ,Mathers JC,Martinez JA

更新日期：2016-08-01 00:00:00

abstract：:Connections between the midbrain dorsolateral periaqueductal grey (dlPAG) and the pontine A5 region have been shown. The stimulation of both regions evokes similar cardiovascular responses: tachycardia and hypertension. Accordingly, we have studied the interactions between dlPAG and A5 region in spontaneously breathin...

journal_title：Journal of physiology and biochemistry

authors： López-González MV,González-García M,Peinado-Aragonés CA,Barbancho MÁ,Díaz-Casares A,Dawid-Milner MS

更新日期：2020-11-01 00:00:00

abstract：:Several studies have suggested that oxidative stress might cause and aggravate the inflammatory state associated with obesity and could be the link between excessive weight gain and its related disorders such as insulin resistance and cardiovascular diseases. Thus, antioxidant treatment has been proposed as a therapy ...

journal_title：Journal of physiology and biochemistry

authors： Prieto-Hontoria PL,Pérez-Matute P,Fernández-Galilea M,Barber A,Martínez JA,Moreno-Aliaga MJ

更新日期：2009-03-01 00:00:00

abstract：:Activation of 5' adenosine monophosphate-activated protein kinase (AMPK) with aminoimidazole carboxamide ribonucleotide (AICAR) increases skeletal muscle glucose uptake and fatty acid oxidation. The purpose of these experiments was to utilize AICAR to enhance palmitate consumption by mitochondria in cultured skeletal ...

journal_title：Journal of physiology and biochemistry

authors： Spangenburg EE,Jackson KC,Schuh RA

更新日期：2013-12-01 00:00:00

abstract：:In the present work, we have evaluated the effect of an acute addition of melatonin on cholecystokinin octapeptide (CCK-8)-evoked Ca(2+) signals and amylase secretion in mouse pancreatic acinar cells. For this purpose, freshly isolated mouse pancreatic acinar cells were loaded with fura-2 to study intracellular free C...

journal_title：Journal of physiology and biochemistry

authors： Santofimia-Castaño P,Ruy DC,Salido GM,González A

更新日期：2013-12-01 00:00:00

abstract：:Differentiation of adipocytes and their aggregation to adipose tissue are critical for mammalian growth and development. MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that play important roles in adipogenesis and lipid metabolism. miR-128-3p may contribute to adipose tissue development according t...

journal_title：Journal of physiology and biochemistry

authors： Chen C,Deng Y,Hu X,Ren H,Zhu J,Fu S,Xie J,Peng Y

更新日期：2018-08-01 00:00:00

abstract：:Type 2 diabetes (T2D) is a complicated systemic disease, and the exact pathogenetic molecular mechanism is unclear. Distinct histone modifications regulate gene expression in certain diseases, but little is known about histone epigenetics in diabetes. In the current study, C57BL/6 J mice were used to build T2D model, ...

journal_title：Journal of physiology and biochemistry

authors： Tu P,Li X,Ma B,Duan H,Zhang Y,Wu R,Ni Z,Jiang P,Wang H,Li M,Zhu J,Li M

更新日期：2015-03-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) refers to a mixture of naturally occurring positional and geometric isomers of linoleic acid that exist in dairy products and meat. The aim of the present work was to study the effects of c-9,t-11 and t-10,c-12 CLA isomers on body fat accumulation and serum lipids in hamsters fed an athe...

journal_title：Journal of physiology and biochemistry

authors： Navarro V,Zabala A,Macarulla MT,Fernández-Quintela A,Rodríguez VM,Simón E,Portillo MP

更新日期：2003-09-01 00:00:00

abstract：:Recently resveratrol, a compound naturally occurring in various plants, has been proposed as a potential anti-obesity compound. The aim of the present work was to analyse the effects of different doses of resveratrol on body fat and serum parameters in rats. Thirty-two male Sprague-Dawley rats were randomly divided in...

journal_title：Journal of physiology and biochemistry

authors： Macarulla MT,Alberdi G,Gómez S,Tueros I,Bald C,Rodríguez VM,Martínez JA,Portillo MP

更新日期：2009-12-01 00:00:00

abstract：:In order to transform cytosolic fructose-1,6-bisphosphatases (FBPase)(EC 3.1.3.11) into potential reductively-modulated chloroplast-type enzymes, we have constructed four chimeric FBPases, which display structural viability as deduced by previous modelling. In the X1-type BV1 and HL1 chimera the N-half of cytosolic su...

journal_title：Journal of physiology and biochemistry

authors： Cazalis R,Chueca A,Sahrawy M,López-Gorgé J

更新日期：2004-03-01 00:00:00

abstract：:Transcriptional factors are easily susceptible to any stimuli, including exercise. Exercise can significantly influence PGC-1 α and AMPK-SIRT1 pathway, as it is involved in the regulation of energy metabolism and mitochondrial biogenesis. Exercise is a major energy deprivation process by which many of transcription fa...

journal_title：Journal of physiology and biochemistry

authors： Thirupathi A,de Souza CT

更新日期：2017-11-01 00:00:00

abstract：:Lipoic acid (LA) is an antioxidant with therapeutic properties on several diseases like diabetes and obesity. Apelin is a novel adipokine with potential beneficial actions on glucose metabolism and insulin resistance. The aim of this study was to examine in 3T3-L1 adipocytes the effects of LA on apelin gene expression...

journal_title：Journal of physiology and biochemistry

authors： Fernández-Galilea M,Pérez-Matute P,Prieto-Hontoria P,Martínez JA,Moreno-Aliaga MJ

更新日期：2011-09-01 00:00:00

abstract：:MicroRNAs (miRNAs), a class of small, single-stranded endogenous RNAs, act as post-transcriptional regulators of gene expression. The ability of one single miRNA regulating multiple functionally related mRNAs makes it a new potential candidate for cancer gene therapy. Let-7s miRNAs have been demonstrated as tumor-supp...

journal_title：Journal of physiology and biochemistry

authors： Wang QZ,Lv YH,Gong YH,Li ZF,Xu W,Diao Y,Xu R

更新日期：2012-03-01 00:00:00

abstract：:Previous studies have shown that stromal interaction molecule1 (STIM1)-mediated store-operated Ca2+ entry (SOCE) contributes to intracellular Ca2+ accumulation in H9C2 cells subjected to hypoxia/reoxygenation(H/R) injury. The aim of the present study was to investigate the effect of resveratrol on STIM1-mediated intra...

journal_title：Journal of physiology and biochemistry

authors： Xu H,Cheng J,Wang X,Liu H,Wang S,Wu J,Xu B,Chen A,He F

更新日期：2019-11-01 00:00:00

abstract：:The prevalence of non-alcoholic fatty pancreas disease (NAFPD) is increasing in parallel with obesity rates. Stress-related alterations in endoplasmic reticulum (ER), such as the unfolded protein response (UPR), are associated with obesity. The aim of this study was to investigate ER imbalance in the pancreas of a mic...

journal_title：Journal of physiology and biochemistry

authors： Soeda J,Mouralidarane A,Cordero P,Li J,Nguyen V,Carter R,Kapur SR,Pombo J,Poston L,Taylor PD,Vinciguerra M,Oben JA

更新日期：2016-06-01 00:00:00

abstract：:This study was designed to investigate effects of raloxifene (RLX) and estradiol on bone formation and resorption in intact and ovariectomized (ovx) rat models. In the intact model, a total of 24 adult female rats were divided into three groups: Controls subcutaneously received saline alone. RLX (2 mg/kg) and estradio...

journal_title：Journal of physiology and biochemistry

authors： Canpolat S,Tug N,Seyran AD,Kumru S,Yilmaz B

更新日期：2010-03-01 00:00:00

abstract：:Two groups of rats were fed on diets with protein from a marine specie holothuria (Holothuria forskali) or casein (for the control group) during 16 days with the aim of assessing the nutritional value of the holothuria protein. Several serum lipid levels were also determined. The results of the nutritive parameters in...

journal_title：Journal of physiology and biochemistry

authors： Rodríguez E,González M,Caride B,Lamas MA,Taboada MC

更新日期：2000-03-01 00:00:00

abstract：:The effect of long-lasting in vivo restriction of nitric oxide (NO) bioavailability on cardiac and renal P-type ATPases critical for intracellular ion homeostasis is controversial. Previous work has shown in eNOS knockout (eNOS(-/-)) mice hearts that Na(+)/K(+)- and Ca(2+)-ATPase activities were depressed but the unde...

journal_title：Journal of physiology and biochemistry

authors： Rezende DC,Pôças ES,Muzi-Filho H,Cunha VM,Caricati-Neto A,Jurkiewicz A,Noël F,Quintas LE

更新日期：2013-06-01 00:00:00

abstract：:In order to observe the effects of nicotine on protein expression in rat vascular smooth muscle cells (SMCs), nicotine treated SMCs were studied by proteomic technologies combining two-dimensional electrophoresis (2-DE) and peptide mass fingerprinting (PMF). Real-time RT-PCR was used to validate the differentially exp...

journal_title：Journal of physiology and biochemistry

authors： Wang Z,Wu W,Fang X,Wang Y,Xiao C,Zhao R,Wang L,Qiao Z

更新日期：2007-06-01 00:00:00