The current status of melanoma early detection and screening.

abstract：:Many genodermatoses have distinct oral features that may help identify or confirm a genetic diagnosis. Oral features of the disorders described here are summarized in Table 1. These conditions provide clear examples of rapid progress in the field of genetic technology relevant to patient care. Less than a decade ago, ...

journal_title：Dermatologic clinics

authors： Hand JL,Rogers RS 3rd

更新日期：2003-01-01 00:00:00

abstract：:The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more ...

journal_title：Dermatologic clinics

authors： Menter MA,Griffiths CE

更新日期：2015-01-01 00:00:00

abstract：:Black patients who desire cosmetic surgery have not had many treatment options or services available to them. At this time, the requests for specific cosmetic surgical procedures by black patients have far exceeded the number of cosmetic surgeons able to meet their needs. A surgeon who calls himself or herself a cosme...

journal_title：Dermatologic clinics

authors： Pierce HE Jr

更新日期：1988-07-01 00:00:00

abstract：:Normal and malignant pigment cells are known targets for many hormones. Besides alpha-melanocyte-stimulating hormone and the steroidal hormones estrogen, testosterone, and glucocorticoids, factors produced by other epidermal cells can affect melanization and proliferation of pigment cells. Among those factors are the ...

journal_title：Dermatologic clinics

authors： Abdel-Malek ZA

更新日期：1988-04-01 00:00:00

abstract：:The clinical diagnosis of malignant melanoma requires the following: an acceptance of the concept of "in situ" malignancy, both clinically and histologically; a high index of suspicion concerning any pigmented lesion; recalling the mnemonic "remember your A,B,C,D's"; and a knowledge of the clinical simulators of malig...

journal_title：Dermatologic clinics

authors： Friedman RJ,Rigel DS

更新日期：1985-04-01 00:00:00

abstract：:Surgery for skin cancer is a major part of clinical dermatology, and the largest single component of dermatologic surgery practice. In general, residency training in dermatology provides comprehensive training in the theory and practice of skin cancer surgery. Practicing dermatologists are similarly expert in this are...

journal_title：Dermatologic clinics

authors： Alam M,Waldman A,Maher IA

更新日期：2016-07-01 00:00:00

abstract：:Traumatic panniculitis refers to changes in the subcutaneous fat related to physical or chemical agents. The clinical picture of traumatic panniculitis is nonspecific. Cutaneous lesions are indurated, warm, red, subcutaneous plaques or nodules not necessary related to the intensity of the injury. The histologic pictur...

journal_title：Dermatologic clinics

authors： Moreno A,Marcoval J,Peyri J

更新日期：2008-10-01 00:00:00

abstract：:Laryngo-onycho-cutaneous (LOC) syndrome was reclassified as a subtype of junctional epidermolysis bullosa (JEB) based on clinical features similar to JEB and its association, in the majority of patients from the Punjab, with a unique mutation affecting the N terminus of the alpha3 chain of LM332. Although LOC syndrome...

journal_title：Dermatologic clinics

authors： Cohn HI,Murrell DF

更新日期：2010-01-01 00:00:00

abstract：:Azathioprine, cyclophosphamide, and cyclosporine are immunosuppressive agents commonly used by dermatologists. Azathioprine has a good safety profile and is preferred by most dermatologists for the treatment of bullous pemphigoid, cutaneous vasculitides, chronic eczematous dermatitides, and cutaneous manifestations of...

journal_title：Dermatologic clinics

authors： Ho VC,Zloty DM

更新日期：1993-01-01 00:00:00

abstract：:Large defects may at first appear to be too big to close in a side-to-side fashion. Certain wounds and situations may call for healing with second intent. Undermining and pulley sutures are very helpful in bringing together wound edges of certain large openings. Partial closures may decrease the tendency to exert unwa...

journal_title：Dermatologic clinics

authors： Shelton RM

更新日期：2001-07-01 00:00:00

abstract：:In the same way that it often is necessary to perform chemical and biological analysis of skin and body fluids in the management of skin disease, it may be necessary to analyze the chemical environment. Some analyses, such as those for nickel, chromate, and formaldehyde, require only simple tests. Others require compl...

journal_title：Dermatologic clinics

authors： Fregert S

更新日期：1988-01-01 00:00:00

abstract：:Ultraviolet (UV) radiation contributes to the development of skin cancer through direct and indirect DNA damage, production of reactive oxygen species, and local immunomodulation. The association between UV radiation and skin cancer has raised concern for the risk of carcinogenesis following phototherapy. The photocar...

journal_title：Dermatologic clinics

authors： Thompson KG,Kim N

更新日期：2020-01-01 00:00:00

abstract：:Cutaneous manifestations of thyroid disease are protean in nature and can be divided into specific lesions such as the thyroglossal duct cyst and cutaneous metastases from thyroid malignancy, nonspecific signs secondary to thyroid hormone imbalance, and associated dermatologic and systemic disorders. This review repre...

journal_title：Dermatologic clinics

authors： Leonhardt JM,Heymann WR

更新日期：2002-07-01 00:00:00

abstract：:Many lesions that appear in the oral cavity manifest as a nodule or swelling. A particular lesion may have the clinical characteristics of several entities, and a differential diagnosis should be generated, with a final diagnosis reached by microscopic examination. This article discusses and shows the clinical feature...

journal_title：Dermatologic clinics

authors： Van Dis ML

更新日期：1996-04-01 00:00:00

abstract：:The terms "palisaded neutrophilic and granulomatous dermatitis," "interstitial granulomatous dermatitis," and the subset "interstitial granulomatous drug reaction" are a source of confusion. There exists substantial overlap among the entities with few strict distinguishing features. We review the literature and highli...

journal_title：Dermatologic clinics

authors： Rosenbach M,English JC 3rd

更新日期：2015-07-01 00:00:00

abstract：:Current aesthetic dermatology rejuvenation options offer minimally invasive, more affordable alternatives to traditional cosmetic surgery. Chemical peels and laser resurfacing can significantly improve the appearance of the skin and stimulate neocollagenesis; botulinum toxin reduces the appearance of dynamic facial li...

journal_title：Dermatologic clinics

authors： Hirsch R,Stier M

更新日期：2009-10-01 00:00:00

abstract：:In Tajikistan, dermatologic services are available across the country. Yet, the most experienced dermatologists work at the National Republic Center for Dermatology and Venereology (NRCDV). Patients from across the country bypass local dermatologists and self-refer to NRCDV. Furthermore, no formal mechanisms exist for...

journal_title：Dermatologic clinics

authors： Lotfizadeh A,Sultonov RA,Morim A,Tavakol S,Daneshvar M,Qosimov AM,Maurer T

更新日期：2021-01-01 00:00:00

abstract：:Pemphigus is an autoimmune intraepithelial blistering disease of the skin and mucous membranes that is characterized in part by the presence of circulating IgG autoantibodies. These autoantibodies, which have been shown to be pathogenic, bind to complexes on the keratinocyte cell surface and have been utilized to esta...

journal_title：Dermatologic clinics

authors： Korman NJ

更新日期：1990-10-01 00:00:00

abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...

journal_title：Dermatologic clinics

authors： Webster G,Del Rosso JQ

更新日期：2007-04-01 00:00:00

abstract：:Rickettsialpox is a member of the spotted-fever group of the rickettsioses and results from an infection with Rickettsia akari. This microbe is transmitted by the bite of the house-mouse mite Liponyssoides sanguineus. Patents experience fevers, sweats, headaches, and a vesicular eruption over the trunk and extremities...

journal_title：Dermatologic clinics

authors： Boyd AS

更新日期：1997-04-01 00:00:00

abstract：:A compendium of uncommon dermatologic treatments, both medical and surgical, are presented. This article is based on a survey of the members of the Noah Worcester Dermatologic Society with subsequent additions, including treatment pearls from the Internet and other contributions from practicing dermatologists, as well...

journal_title：Dermatologic clinics

authors： Stone SP

更新日期：2000-04-01 00:00:00

abstract：:The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...

journal_title：Dermatologic clinics

authors： Salvaggio MR,Baddley JW

更新日期：2004-07-01 00:00:00

abstract：:Patient-centered care in dermatologic surgery emphasizes addressing the preferences, values, and concerns of the surgical patient in an effort to improve the overall experience. Impediments affecting the delivery of Mohs micrographic surgical treatment of skin cancers are present throughout the perioperative period. D...

journal_title：Dermatologic clinics

authors： Lee MP,Zullo SW,Sobanko JF,Etzkorn JR

更新日期：2019-07-01 00:00:00

abstract：:It is quite evident the pathogenesis of psoriasis is modulated by immune-mediated mechanisms that invoke activated T cells and inflammatory cytokines, such as tumor necrosis factor-alpha. Current immunosuppressive systemic treatments may be effective in controlling psoriasis to a certain degree but have significant dr...

journal_title：Dermatologic clinics

authors： Yamauchi PS,Gindi V,Lowe NJ

更新日期：2004-10-01 00:00:00

abstract：:Acne vulgaris alters the normal skin physiology, impairing stratum corneum and transepidermal water loss. A male's normal skin physiologic state is different than a female's and may have implications when choosing treatment when the skin is altered in a disease state. Transepidermal water loss, pH, and sebum productio...

journal_title：Dermatologic clinics

authors： McCarty M

更新日期：2016-04-01 00:00:00

abstract：:Discolorations of the skin, such as vitiligo, were recognized thousands of years ago. White spots caused by vitiligo and other disorders have caused significant social opprobrium to those disfigured by these pigmentary disorders, throughout history and still in the present day. Treatments have been desperately sought ...

journal_title：Dermatologic clinics

authors： Nordlund JJ

更新日期：2017-04-01 00:00:00

abstract：:Excising cancer in successive layers and examining the entire underside of each layer in the microscope by the systematic use of frozen sections ensure eradication of the neoplasm, including its "silent" outgrowths, and this is accomplished with the maximal sparing of normal tissue. Fresh-tissue micrographic surgery i...

journal_title：Dermatologic clinics

authors： Mohs FE

更新日期：1989-10-01 00:00:00

abstract：:This article presents solutions to difficult surgical repair problems. Solutions for the repair of defects in the ear (in this case the ear lobule) and upper lip are discussed. A solution is also provided for an exasperating problem that arises when cheek and neck lifts are done. An aid for the design of cutaneous fla...

journal_title：Dermatologic clinics

authors： Gormley DE

更新日期：1989-01-01 00:00:00

abstract：:Native Americans have a rich and complex heritage and culture. Although the genetic pool has changed with increasing integration with other Americans with different ancestry, there are important conditions that are unique to Native Americans, the most prominent example being actinic prurigo. The scientific literature ...

journal_title：Dermatologic clinics

authors： Cornelison RL Jr

更新日期：2003-10-01 00:00:00

abstract：:Pediatric dermatologic disease that have specific therapies and/or specific prophylactic measures are reviewed. Herpes simplex virus and varicella-zoster virus infections, human papillomavirus infections, and molluscum contagiosum infections are discussed with special emphasis on recent advances of therapy and prophyl...

journal_title：Dermatologic clinics

authors： Trizna Z,Tyring SK

更新日期：1998-07-01 00:00:00