Comparison of airway reactivity induced by cold air and metacholine challenges in asthmatic children.

abstract：:Little is known about the respiratory behavior of the intercostal muscles within a neonatal and developmental context. We, therefore, examined intercostal muscle electromyographic (EMG) activity in kittens (1 month old, n = 8; 2 months old, n = 7) during eupnea and heightened respiratory drive induced by hypercapnia. ...

journal_title：Pediatric pulmonology

authors： Watchko JF,Klesh KW,O'Day TL,Guthrie RD

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To examine the independent association of asthma and obesity and of their co-existence with functional exercise capacity among urban adolescents. METHODS:One hundred eighteen Hispanic- and African-American adolescents including 33 obese asthmatics, 18 normal-weight asthmatics, 38 obese non-asthmatics, and 29 n...

journal_title：Pediatric pulmonology

authors： Rastogi D,Khan UI,Isasi CR,Coupey SM

更新日期：2012-11-01 00:00:00

abstract：:Lung transplantation in childhood is a highly specialized clinical practice confined to a few centers around the world. Organ availability remains an important limiting factor in extending the application of this procedure to more infants, children and adolescents. The lungs are the organ most vulnerable to injury, in...

journal_title：Pediatric pulmonology

authors： Mallory GB Jr,Schecter MG,Elidemir O

更新日期：2009-06-01 00:00:00

abstract：:We present a 9-month-old infant with persistent cough refractory to conventional asthma therapy. An extensive evaluation eventually revealed a Chiari I malformation with syringohydromyelia. His cough resolved one month after surgical decompression, suggesting that brainstem compression from the Chiari malformation dir...

journal_title：Pediatric pulmonology

authors： Amos LB,Quintero DR

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD) is one of the most common complications in premature infants. Since inflammation plays a crucial role in the pathogenesis of BPD, anti-inflammatory drugs, such as corticosteroids, have long been the focus of prevention research. In this meta-analysis, we aim to explore the lo...

journal_title：Pediatric pulmonology

authors： Zheng Y,Xiu W,Lin Y,Ren Y,Zhang B,Yang C

更新日期：2019-11-01 00:00:00

abstract：:Indoor aeroallergen exposures increased asthma symptoms in Caucasians, but their determinants and relationship to asthma and allergy in Asians are unclear. This study investigated exposures to cat, cockroach, and Blomia tropicalis allergens in 115 Hong Kong families with asthmatic children. Patients underwent exhaled ...

journal_title：Pediatric pulmonology

authors： Leung TF,Wong YS,Chan IH,Yung E,Sy HY,Lam CW,Wong GW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...

journal_title：Pediatric pulmonology

authors： Usemann J,Demann D,Anagnostopoulou P,Korten I,Gorlanova O,Schulzke S,Frey U,Latzin P

更新日期：2017-10-01 00:00:00

abstract：:The free running test is a useful method for evaluation of exercise-induced bronchospasm in children. In young children this test simulates real-life circumstances and can be done more easily than histamine or methacholine challenges. The interrupter technique is a noninvasive method for measuring airflow resistance d...

journal_title：Pediatric pulmonology

authors： Kannisto S,Vanninen E,Remes K,Korppi M

更新日期：1999-03-01 00:00:00

abstract：:While many factors that contribute to the occurrence of lower respiratory tract infections (LRTI) in Canadian indigenous children have been described, the role of aspiration during swallowing has not been explored in these children. Because of an increase in referrals of indigenous children from our catchment area (Ma...

journal_title：Pediatric pulmonology

authors： Rempel G,Borton B,Esselmont E,Shelton C

更新日期：2011-12-01 00:00:00

abstract：:IL-10 is an anti-inflammatory cytokine that may have a protective role in acute lung injury. IL-10 expression is affected by a single-nucleotide polymorphism (SNP) located at position -1082 (G to A). The A allele is associated with lower IL-10 production. Low IL-10 production has been linked to the development of BPD....

journal_title：Pediatric pulmonology

authors： Yanamandra K,Boggs P,Loggins J,Baier RJ

更新日期：2005-05-01 00:00:00

abstract：:The current bronchopulmonary dysplasia (BPD) is seen in infants born extremely premature, with less severe respiratory distress syndrome (RDS) and who received prenatal steroids-"new BPD". The pathophysiology of BPD is based on an impairment of lung maturation with prenatal and postnatal multi-hit insults and genetic ...

journal_title：Pediatric pulmonology

authors： Kugelman A,Durand M

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Hypoxia and reactive oxygen species (ROS) including H(2)O(2) play major roles in triggering and progression of pulmonary vascular remodeling in persistent pulmonary hypertension. Catalase (CAT), the major endogenous enzyme scavenging H(2)O(2), is regulated in a tissue- and context-specific manner. OBJECTIVE...

journal_title：Pediatric pulmonology

authors： Awad H,Nolette N,Hinton M,Dakshinamurti S

更新日期：2014-09-01 00:00:00

abstract：:Five children with positive serology for human immunodeficiency virus (HIV) infection by enzyme-linked immunosorbent assay and Western blot were followed for chronic pulmonary disease. Lung biopsies were performed in all patients, and confirmed the diagnosis of pulmonary lymphoid hyperplasia. All children demonstrated...

journal_title：Pediatric pulmonology

authors： Rubinstein A,Bernstein LJ,Charytan M,Krieger BZ,Ziprkowski M

更新日期：1988-01-01 00:00:00

abstract：:Respiratory symptoms, atopy, and bronchial reactivity were measured in primary school children living in Lake Munmorah (LM), a coastal town near two power stations, and in Nelson Bay (NB), a coastal town free from any possible major sources of outdoor air pollution. A prevalence survey and longitudinal follow-up study...

journal_title：Pediatric pulmonology

authors： Henry RL,Abramson R,Adler JA,Wlodarcyzk J,Hensley MJ

更新日期：1991-01-01 00:00:00

abstract：:Exposure to chronic constant or intermittent hypoxia (CCH or CIH) may have different effects on growth and development in early life. In this work, we exposed postnatal day 2 (P2) CD1 mice to CCH or CIH (11% O2) for 4 weeks and examined the effect of hypoxia on body and organ growth until P30. Regression analysis show...

journal_title：Pediatric pulmonology

authors： Farahani R,Kanaan A,Gavrialov O,Brunnert S,Douglas RM,Morcillo P,Haddad GG

更新日期：2008-01-01 00:00:00

abstract：:Randomized trials of ribavirin therapy have used clinical scores to assess illness severity. Little information on agreement for these findings between observers has been published. We decided to determine interobserver agreement for (1) a history for apnea or respiratory failure; (2) assessment of cyanosis, respirato...

journal_title：Pediatric pulmonology

authors： Wang EE,Law BJ,Stephens D,Langley JM,MacDonald NE,Robinson JL,Dobson S,McDonald J,Boucher FD,de Carvalho V,Mitchell I

更新日期：1996-07-01 00:00:00

abstract：:Some studies have suggested that lung clearance index (LCI) is age-independent among healthy subjects early in life, which implies that ventilation distribution does not vary with growth. However, other studies of older children and adolescents suggest that ventilation becomes more homogenous with somatic growth. We d...

journal_title：Pediatric pulmonology

authors： Chakr VC,Llapur CJ,Sarria EE,Mattiello R,Kisling J,Tiller C,Kimmel R,Poindexter B,Tepper RS

更新日期：2012-04-01 00:00:00

abstract：:Exercise-induced asthma (EIA) is a possible cause of poor physical performance in children. No data are available on the value of respiratory symptoms to discriminate children with bad physical fitness from children with EIA. We evaluated respiratory symptoms in school-age children during and after exercise in relatio...

journal_title：Pediatric pulmonology

authors： De Baets F,Bodart E,Dramaix-Wilmet M,Van Daele S,de Bilderling G,Masset S,Vermeire P,Michel O

更新日期：2005-04-01 00:00:00

abstract：:Airway obstruction in children is a rare, but difficult clinical problem, with no clear agreement on optimal therapeutic approach. Stenting of the airway has been used successfully in adults, and is an attractive alternative in children. Fundamental differences of pediatric compared to adult use include the benign nat...

journal_title：Pediatric pulmonology

authors： Nicolai T

更新日期：2008-04-01 00:00:00

abstract：:There is currently no validated scoring system for quantification of airway secretions in children. A user friendly, valid scoring system of airway secretions during flexible bronchoscopy (FB) would be useful for comparative purposes in clinical medicine and research. The objective of this study was to validate our br...

journal_title：Pediatric pulmonology

authors： Chang AB,Faoagali J,Cox NC,Marchant JM,Dean B,Petsky HL,Masters IB

更新日期：2006-09-01 00:00:00

abstract：:Twenty patients with cystic fibrosis (CF) were trained to mobilize intrabronchial secretions by a new method of positive expiratory pressure mask (PEP mask) physiotherapy (PT). Patients repeatedly expired forcefully through the PEP mask; expiratory resistance was varied by eight different internal diameter resistors a...

journal_title：Pediatric pulmonology

authors： Oberwaldner B,Evans JC,Zach MS

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVES:High incidence of genetic alterations at the microsatellite (MS) DNA level has been reported in asthmatic adults. WORKING HYPOTHESIS:The aim of this study was to investigate whether microsatellite instability (MSI) and loss of heterozygosity (LOH) were detectable phenomena in children with asthma. METHODOL...

journal_title：Pediatric pulmonology

authors： Thomou C,Paraskakis E,Neofytou E,Kalmanti M,Siafakas NM,Tzortzaki EG

更新日期：2009-10-01 00:00:00

abstract：:To promote early screening of patients with suspected Primary Ciliary Dyskinesia (PCD), nasal nitric oxide (nNO) measurements during tidal breathing (TB) have been developed for children unable to ensure velum closure (VC) during breath hold or expiration against resistance. To investigate technical and practical issu...

journal_title：Pediatric pulmonology

authors： Beydon N,Chambellan A,Alberti C,de Blic J,Clément A,Escudier E,Le Bourgeois M

更新日期：2015-12-01 00:00:00

abstract：:To determine the role of calmodulin in postnatal lung growth and development, 4-week-old rats were injected intraperitoneally on consecutive days with trifluoperazine (TFP), a potent and specific calmodulin antagonist, for a period fo 3 weeks and studied in comparison with normal controls and undernourished weight-mat...

journal_title：Pediatric pulmonology

authors： Ofulue AF,Sekhon H,Cherukupalli K,Khadempour H,Thurlbeck WM

更新日期：1991-01-01 00:00:00

abstract：INTRODUCTION:In moderate-severe asthma exacerbation, salbutamol by inhaler (MDI) is superior to salbutamol delivered by nebulizer (NEB); however, to our knowledge, no studies in children with exclusively severe exacerbations were performed. OBJECTIVE:To compare the efficacy of salbutamol and ipratropium bromide by MDI...

journal_title：Pediatric pulmonology

authors： Iramain R,Castro-Rodriguez JA,Jara A,Cardozo L,Bogado N,Morinigo R,De Jesús R

更新日期：2019-04-01 00:00:00

abstract：:In adults, the term specific pulmonary renal syndrome describes disorders with pulmonary and glomerular manifestations and includes Wegener's granulomatosis, Goodpasture disease, and systemic lupus erythematosus. Nonspecific pulmonary renal syndrome refers to either pulmonary disease complicating glomerular disease, o...

journal_title：Pediatric pulmonology

authors： von Vigier RO,Trummler SA,Laux-End R,Sauvain MJ,Truttmann AC,Bianchetti MG

更新日期：2000-05-01 00:00:00

abstract：:Malacoplakia is an unusual inflammatory condition with distinctive histologic features. Involvement of the lung is quite uncommon and is rarely described in paediatrics. We report on a case of pulmonary malacoplakia in a teenage girl. ...

journal_title：Pediatric pulmonology

authors： Kumar P,Rassl DM,Hamilton JR,Spencer DA

更新日期：2003-11-01 00:00:00

abstract：:In this article, we describe existing CF registries with a focus on US registry data collected through the CF Foundation Patient Registry (CFFPR) and the Epidemiologic Study of CF (ESCF); highlight what registries have taught us regarding epidemiology of CF; showcase the impact of registries on research and clinical c...

journal_title：Pediatric pulmonology

authors： Fink AK,Loeffler DR,Marshall BC,Goss CH,Morgan WJ

更新日期：2017-11-01 00:00:00

abstract：:The cytokines tumor necrosis factor-alpha (TNF-alpha), interleukin-8 (IL-8), and intercellular adhesion molecule-1 (ICAM-1) have important roles in regulating neutrophil migration and the inflammatory response. To determine whether the concentration of these cytokines and soluble ICAM-1 (sICAM-1) in sputum was increas...

journal_title：Pediatric pulmonology

authors： Salva PS,Doyle NA,Graham L,Eigen H,Doerschuk CM

更新日期：1996-01-01 00:00:00

abstract：:Our study was aimed at elucidating the effect of strenuous maternal exercise (running at a speed of 20 m/min) on fetal somatic growth and lung development. Dams were separated into three groups: (1) exercising during the entire course of pregnancy; (2) exercising from the 16th to the 20th gestational day; and (3) cont...

journal_title：Pediatric pulmonology

authors： Nagai A,Sakamoto K,Konno K

更新日期：1993-06-01 00:00:00