Effect of uterine space and fetal sex on conceptus development and in vitro release of progesterone and estrone from regions of the porcine placenta throughout gestation.


:Intact (n = 17) and unilaterally hysterectomized-ovariectomized (UHOX, n = 19) gilts were used to study conceptus development and the steroidogenic capability of three regions of the porcine placenta under normal and crowded intrauterine conditions. Gilts were hysterectomized on either Days 30, 50, 70, or 90 of gestation. Placentas were combined according to the sex of the fetus associated with the placental unit, except at Day 30, when all were combined. Placentas were cut into three regions: middle, inner, and polar. Placental tissues were incubated for 0, 1, 5, and 3 hr, and concentrations of progesterone (P4) and estrone (E1) in the incubation medium were determined. Fetal survival rate was greater (P < 0.01, 0.05, and 0.001 at days 50, 70, and 90, respectively) in intact than in UHOX gilts. Placental length and weight, fetal length and weight, and allantoic fluid volume were greater (P < 0.05, 0.001, 0.05, and 0.001, respectively) in intact than in UHOX gilts. P4 concentration was lower (P < 0.001, 0.002, and 0.001 at Days 50, 70, and 90, respectively) in the incubation medium of polar region placenta compared with the other regions. The release of P4 was greater (P < 0.005) from the placentas of intact versus UHOX gilts at Day 90 but was not different at Days 30, 50, or 70. The sex of the fetus did not affect placental P4 release. The region of the placenta affected E1 release at Day 30 (P < 0.01, greater in polar section) and Day 50 (P < 0.06, less in polar section). There was no effect of uterine status on E1 release.(ABSTRACT TRUNCATED AT 250 WORDS)


Domest Anim Endocrinol


Tarraf CG,Knight JW




Has Abstract


1995-01-01 00:00:00














  • Endocrine and endometrial secretory protein changes associated with uterine receptivity in sheep.

    abstract::Crossbred ovariectomized ewes were treated with steroid therapies determined previously to be adequate (progesterone-primed) or inadequate (unprimed) for embryonic development in order to determine actual serum concentrations of replaced steroid hormones achieved by such treatments and to identify secreted endometrial...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Moffatt RJ,Bettencourt CM,Keisler DH

    更新日期:1993-04-01 00:00:00

  • Neuroimmunoregulation and natural immunity.

    abstract::The development and function of the immune system is regulated by neuroendocrine factors. Immune function may be divided into adaptive and natural immunity. Adaptive immune responses are driven by specific determinants of the antigen (epitopes), require 5-10 d to fully develop, and show an accelerated or memory respon...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章,评审


    authors: Berczi I,Chow DA,Sabbadini ER

    更新日期:1998-09-01 00:00:00

  • Effects of oxytocin, lipopolysaccharide (LPS), and polyunsaturated fatty acids on prostaglandin secretion and gene expression in equine endometrial explant cultures.

    abstract::Increased secretion of prostaglandin F(2)α (PGF(2)α) within the uterus because of uterine inflammation can cause luteolysis and result in early embryonic loss. Supplementation with polyunsaturated fatty acids (PUFAs) has been shown to influence PG production in many species, although the effects on the mare remain unk...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Penrod LV,Allen RE,Turner JL,Limesand SW,Arns MJ

    更新日期:2013-01-01 00:00:00

  • Acute handling disturbance modulates plasma insulin-like growth factor binding proteins in rainbow trout (Oncorhynchus mykiss).

    abstract::The effects of acute stressor exposure on proximal (growth hormone [GH]) and distal (insulin-like growth factor-I [IFG-I] and insulin-like growth factor-binding proteins [IFGBPs]) components of the somatotropic axis are poorly understood in finfish. Rainbow trout (Oncorhynchus mykiss) were exposed to a 5-min handling ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Shepherd BS,Aluru N,Vijayan MM

    更新日期:2011-04-01 00:00:00

  • Effect of stage of lactation and gestation on milking-induced hormone release in lactating dairy cows.

    abstract::Three experiments were conducted to better understand why milking-induced prolactin (PRL) release decreases as lactation advances. Experiment 1 compared the effects of milking, 2-min manual stimulation of the mammary gland (without milking), or injection of 1 IU of oxytocin (without milking) on hormonal release in ear...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Lacasse P,Zhao X,Ollier S

    更新日期:2019-01-01 00:00:00

  • Detection of twin pregnancies in ewes by pregnancy-associated glycoprotein assay and transabdominal ultrasonography.

    abstract::The objectives of the present study were to evaluate and compare the accuracy of transabdominal ultrasonography and pregnancy-associated glycoprotein (PAG) assay in the diagnosis of twin pregnancies in ewes and to evaluate the utility of the PAG assay for predicting fetal gender in singleton pregnancies. The animals i...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Alkan H,Kivrak MB,Satilmis F,Tekindal MA,Dinc DA

    更新日期:2020-07-01 00:00:00

  • The molecular basis for bidirectional communication between the immune and neuroendocrine systems.

    abstract::IL-2 has analgesic effects in both central and peripheral nervous systems. There are two distinct domains in IL-2 molecule mediating immunologic and analgesic activity, respectively. The analgesic domain of IL-2 may be composed of the 44th Phe, 45th Tyr, 107th Tyr, and 117th Phe residues that are located closely in th...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章,评审


    authors: Jiang CL,Lu CL,Liu XY

    更新日期:1998-09-01 00:00:00

  • Role of luteal biosynthesis of prostaglandin F2α on function and structure of the corpus luteum during luteolysis in heifers.

    abstract::The role of endogenous prostaglandin F2α (PGF) in the induction of luteolysis by exogenous PGF was studied by simultaneous inhibition of endogenous PGF with flunixin meglumine (FM). Groups were controls (n = 8), PGF treated (n = 8), and FM + PGF treated (n = 9). Treatments were given 10 d postovulation at hours 0, 8, ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Pinaffi FLV,Araujo ER,Ginther OJ

    更新日期:2018-04-01 00:00:00

  • Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs.

    abstract::Environment enrichment is a rising topic for animal welfare but measures to identify effective enrichment interventions are lacking. In humans and rodent species, environmental enrichment increases brain-derived neurotrophic factor (BDNF), the most abundant neurotrophin in the brain. Higher BDNF concentration is ultim...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Rault JL,Lawrence AJ,Ralph CR

    更新日期:2018-10-01 00:00:00

  • Influence of light environment and photoperiod on plasma melatonin and cortisol profiles in young domestic boars, comparing two commercial melatonin assays.

    abstract::Eighteen crossbred boars, three siblings from each of six litters, were distributed randomly among three groups after weaning. The 'Natural long-day' group was housed in a standard room with windows, whereas the 'Artificial long-day' and 'Artificial short-day' groups were housed in light-sealed rooms and under an arti...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Andersson H,Lillpers K,Rydhmer L,Forsberg M

    更新日期:2000-11-01 00:00:00

  • Endotoxin induces delayed ovulation following endocrine aberration during the proestrous phase in Holstein heifers.

    abstract::The effect of endotoxin on follicular growth and on secretion of LH, estradiol-17beta, progesterone and cortisol during the proestrous phase in cattle was investigated. Holstein heifers were treated with PGF2alpha at 11-13 d after ovulation to induce luteolysis. At 42 hr after PGF2alpha treatment, heifers were adminis...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Suzuki C,Yoshioka K,Iwamura S,Hirose H

    更新日期:2001-05-01 00:00:00

  • Milk production correlates negatively with plasma levels of pregnancy-associated glycoprotein (PAG) during the early fetal period in high producing dairy cows with live fetuses.

    abstract::This study was designed to establish possible factors affecting plasma pregnancy-associated glycoprotein (PAG) concentrations during early pregnancy in high producing dairy cows with live fetuses. Blood samples were obtained on days 35, 42, 49, 56 and 63 of gestation from 80 lactating cows in two herds carrying live f...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: López-Gatius F,Garbayo JM,Santolaria P,Yániz J,Ayad A,de Sousa NM,Beckers JF

    更新日期:2007-01-01 00:00:00

  • Effects of prenatal stress on the fetal calf.

    abstract::Twelve pregnant Brahman cows were randomly assigned to one of two treatment groups: 1) transported in a stock trailer for 24.2 km, unloaded at a second farm and penned for 1 hr, and then returned to the original farm (TRANS, n = 6); or 2) walked through the handling facilities (SHAM, n = 6). Treatments were repeated a...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Lay DC Jr,Randel RD,Friend TH,Carroll JA,Welsh TH Jr,Jenkins OC,Neuendorff DA,Bushong DM,Kapp GM

    更新日期:1997-03-01 00:00:00

  • Behavioral and physiological responses to intraperitoneal injection of zymosan in chicks.

    abstract::Zymosan is a cell wall component of the yeast Saccharomyces cerevisiae and produces severe inflammatory responses in mammals. When zymosan is peripherally injected in mammals, it induces several behavioral and physiological changes including anorexia and hyperthermia. However, to our knowledge, behavioral and physiolo...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Tachibana T,Nakatani A,Islam Khan MS,Makino R,Cline MA

    更新日期:2020-07-01 00:00:00

  • Effects of Prostaglandins E2 and F2α on the in vitro maturation of bovine oocytes.

    abstract::We aimed to elucidate the effects of PGE2 and PGF2α on the in vitro maturation (IVM) of bovine oocytes. First, cumulus-oocyte complexes were matured in the media supplemented with or without PGE2, PGF2α, or PGE2 plus PGF2α for the final 24, 12, or 6 h of culture. Then, the cumulus-oocyte complexes were matured in the ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Rodrigues SAD,Pontelo TP,Kussano NR,Kawamoto TS,Leme LO,Caixeta FMC,Pfeifer LFM,Franco MM,Dode MAN

    更新日期:2020-07-01 00:00:00

  • Relationship between in vitro somatotroph function and growth in three-week-old barrows.

    abstract::The relationship between in vitro somatotroph function and growth was examined in piglets demonstrating a continuous range of growth characteristics. Twenty barrows were sacrificed at 3 weeks of age for the collection of pituitary tissue and blood. Pituitary cells from each animal were cultured and exposed to vehicle ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Matteri RL,Lamberson WR,Keisler DH

    更新日期:1994-10-01 00:00:00

  • Elevated temperature (heat stress) in vitro reduces androstenedione and estradiol and increases progesterone secretion by follicular cells from bovine dominant follicles.

    abstract::Dairy cattle are susceptible to heat stress-induced reductions in fertility; however, direct effects of hyperthermia on specific reproductive functions are difficult to determine in vivo. The objective of this experiment was to examine the effect of elevated temperature in vitro on follicular steroidogenesis, to gain ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Bridges PJ,Brusie MA,Fortune JE

    更新日期:2005-10-01 00:00:00

  • Effects of domperidone and thyrotropin-releasing hormone on secretion of luteinizing hormone and prolactin during the luteal phase and following induction of luteal regression in sheep.

    abstract::Effects of domperidone, a peripheral dopamine receptor antagonist, on secretion of LH and prolactin were studied during the luteal phase and following administration of PGF2 alpha. Since hyperprolactinemia has been reported to inhibit secretion of LH in ewes, effects of thyrotropin-releasing hormone (TRH) also were ex...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Deaver DR,Keisler DH,Dailey RA

    更新日期:1987-04-01 00:00:00

  • Sociosexual stimuli and gonadotropin-releasing hormone/luteinizing hormone secretion in sheep and goats.

    abstract::Sociosexual stimuli have a profound effect on the physiology of all species. Sheep and goats provide an ideal model to study the impact of sociosexual stimuli on the hypothalamic-pituitary-gonadal axis because we can use the robust changes in the pulsatile secretion of luteinizing hormone as a bioassay of gonadotropin...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章,评审


    authors: Hawken PA,Martin GB

    更新日期:2012-08-01 00:00:00

  • Characterization of and radioimmunoassay for canine thyroglobulin.

    abstract::Canine thyroglobulin (cTg) has been isolated and purified. It has similar electrophoretic patterns as Tg from other mammalian species. The main fraction had a MW of 660,000, whereas also fractions of a MW of approximately 1,300,000 (dimer) and 330,000 (subunit) were present. The iodine content was 0.8 to 1.0% (w/w). c...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Verschueren CP,Selman PJ,de Vijlder JJ,Mol JA

    更新日期:1991-10-01 00:00:00

  • Genetically caused retarded growth in animals.

    abstract::Growth process of animals is regulated by a multitude of physiological pathways among which components of the somatotropic axis play a key role. A number of severe, simply inherited growth disturbances have been identified in humans, laboratory and farm animals. These disorders are controlled by defective alleles at m...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章,评审


    authors: Sellier P

    更新日期:2000-08-01 00:00:00

  • Interactions between environmental temperature and porcine growth hormone (pGH) treatment in neonatal pigs.

    abstract::Age-dependent interactions between environmental temperature and porcine growth hormone (pGH) treatment on the function of the somatotrophic axis were evaluated in the neonatal pig. At 3 d of age, 40 Landrace x Yorkshire x Duroc piglets received intraperitoneal implants containing either recombinant pGH (0.5 mg/d; n =...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Carroll JA,Buonomo FC,Becker BA,Matteri RL

    更新日期:1999-02-01 00:00:00

  • Plasma ghrelin and oxyntomodulin concentrations in lactating dairy cows receiving abomasal soybean oil, corn starch, and casein infusions.

    abstract::The effects of increased postruminal supply of casein, corn starch, and soybean oil on plasma concentrations of the gastrointestinal hormones ghrelin and oxyntomodulin (OXM) were investigated. Four mid-lactation Holstein cows were used in a 4 x 4 Latin square. Treatments were continuous abomasal infusions (23 h/d) for...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Relling AE,Loerch SC,Reynolds CK

    更新日期:2010-05-01 00:00:00

  • Establishment of a reliable extraction method of estrone sulfate from bovine plasma for detection of the peripheral level during the regular estrous cycle by radioimmunoassay.

    abstract::A simple extraction and assay technique of estrone sulfate in bovine blood was developed with the object of detecting the peripheral level of estrone sulfate in a normal estrous cycle or in early pregnancy. Estrone sulfate in bovine plasma was extracted with a small reversed phase cartridge. The steroid conjugate reta...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Hirako M,Takahashi H,Domeki I

    更新日期:1996-05-01 00:00:00

  • Characterization of transgenic livestock production.

    abstract::The objective of transgenic livestock improvement projects is to develop and bring to market superior breeding stock, as well as germplasm for the artificial insemination and embryo transfer industries. Livestock animal biotechnology programs hold the promise of achieving, in a single generation, improvements in comme...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章,评审


    authors: Pinkert CA,Dyer TJ,Kooyman DL,Kiehm DJ

    更新日期:1990-01-01 00:00:00

  • Plasma concentrations of ACTH precursors correlate with pituitary size and resistance to dexamethasone in dogs with pituitary-dependent hyperadrenocorticism.

    abstract::This study was performed to determine whether in dogs with pituitary-dependent hyperadrenocorticism (PDH) excessive release of adrenocorticotrophic hormone (ACTH) is accompanied by secretion of ACTH precursor molecules. In addition, we investigated whether the plasma ACTH precursor concentrations were correlated with ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Bosje JT,Rijnberk A,Mol JA,Voorhout G,Kooistra HS

    更新日期:2002-06-01 00:00:00

  • Insulin-like growth factor binding protein-3: its biological effect on bovine granulosa cells.

    abstract::This study was aimed at testing the hypothesis that insulin-like growth factor binding protein (IGFBP)-3 can modulate hormone-dependent differentiation of granulosa cells in vitro. Granulosa cells from small (1 to 5 mm) follicles were collected from cattle, cultured for 2 d in medium containing 10% fetal calf serum, w...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Spicer LJ,Chamberlain CS

    更新日期:1999-01-01 00:00:00

  • Effects of N-methyl-D, L-aspartate on secretion of growth hormone-releasing hormone from the boar hypothalamic-preoptic area and median eminence in vitro.

    abstract::N-methyl-D, L-aspartate (NMA) elicited secretion of growth hormone (GH)-releasing hormone from both the hypothalamic-preoptic area and the median eminence that were collected from boars. We suggest that the previously described increase in GH secretion that follows peripheral treatment of swine with NMA is attributabl...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Estienne MJ,McElwain KV,Barrett JB,Barb CR

    更新日期:1999-11-01 00:00:00

  • Luteinizing hormone secretion in hypophysial stalk-transected gilts given hydrocortisone acetate and pulsatile gonadotropin-releasing hormone.

    abstract::The site within the hypothalamic-pituitary axis at which cortisol acts to inhibit luteinizing hormone (LH) secretion was investigated in female pigs. Six ovariectomized, hypophysial stalk-transected (HST) gilts were given 1 microgram pulses of gonadotropin releasing-hormone (GnRH) iv every 45 min from day 0 to 12. On ...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Estienne MJ,Barb CR,Kesner JS,Kraeling RR,Rampacek GB

    更新日期:1991-07-01 00:00:00

  • Dexamethasone treatment at birth enhances neonatal growth in swine.

    abstract::The objective of the present study was to determine if dexamethasone (Dex; a potent synthetic glucocorticoid) treatment at birth would alter postnatal growth in neonatal pigs. Forty crossbred pigs were injected i.m. with either sterile saline (Cont; n = 10 males and 10 females) or Dex (1 mg/kg; n = 10 males and 10 fem...

    journal_title:Domestic animal endocrinology

    pub_type: 杂志文章


    authors: Carroll JA

    更新日期:2001-08-01 00:00:00