Abstract:
:An attenuated ovulatory rise in circulating concentrations of LH is characteristically associated with the first seasonal reproductive cycle of horse mares. Unlike ovulations (OV) of subsequent estrous cycles, the first OV of the breeding season (OV1) is not preceded by elevated concentrations of progesterone (PROG). Hence, the ability of pretreatment with PROG to abolish attenuation of LH-secretion associated with OV1 was investigated. Ten nonpregnant anestrous mares were randomly divided into 2 groups; control (C) and treated (T). Per individual, when diameter of the largest follicle was consistently greater than or equal to 35 mm, C mares received 3 times daily injections of cottonseed oil (IM), for 15 d or until OV, while T mares received exogenous PROG (IM) for 15 d, in a manner designed to mimic a diestrous pattern of release. Jugular blood samples were collected daily from onset of treatment through 10 d following the third OV (OV3). Repeated measures analyses of area under the ovulatory LH-rise (AUC) and the maximum concentration of LH associated with OV (MAX) revealed a significant main effect of OV (P less than .005) but no main effect of group or OV by group interaction (P greater than or equal to .5). When groups were combined, a significant increase in mean AUC and MAX from OV1 to OV3 was observed (P less than .01). To evaluate the influence of hypothalamic-hypophyseal recrudescence on ovulatory LH-release at OV1, 16 mares were bred to foal, and subsequently initiate reproductive activity, early (E; mid April; n = 8) or late (L; mid July; n = 8) in the year. A significant OV (1, 2 or 3) by group (E or L) interaction was observed for AUC (P less than .06) and MAX (P less than .04). Mean AUC and MAX increased progressively from OV1 to OV3 in E mares (P less than .05). In L mares, neither AUC or MAX changed from OV1 to OV3 (P greater than .4). Based on these data, we suggest that attenuation of the LH-rise at OV1 in the mare, is a consequence of incomplete recrudescence of the hypothalamic-pituitary axis.
journal_name
Domest Anim Endocrinoljournal_title
Domestic animal endocrinologyauthors
Silvia PJ,Fitzgerald BPdoi
10.1016/0739-7240(91)90061-nsubject
Has Abstractpub_date
1991-04-01 00:00:00pages
255-64issue
2eissn
0739-7240issn
1879-0054pii
0739-7240(91)90061-Njournal_volume
8pub_type
杂志文章abstract::In vitro release of progesterone (P4) and estrone (E1) by the porcine placenta was characterized at 12 days of gestation between d 20 and 110. Placental P4 rose linearly from d 25 to 40, plateaued between d 40 and 50, continued to increase to a peak concentration at d 100, then decreased sharply to d 110. Placental E1...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/0739-7240(90)90007-m
更新日期:1990-10-01 00:00:00
abstract::Prolonged hyperinsulinemia is thought to be the cause of equine endocrinopathic laminitis, a common and crippling disease of the foot, for which there are no pharmacologic treatments other than pain relief. It has been suggested that insulin causes its effects on the lamellae by activating IGF-1 receptors (IGF-1R), as...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2020.106510
更新日期:2021-01-01 00:00:00
abstract::Experiments were conducted to determine if a nocturnal rise in serum melatonin occurs in prepubertal gilts and whether acute exposure of gilts to light during the dark period abruptly reduces serum concentrations of melatonin. In experiment 1, 12 prepubertal crossbred gilts (Duroc x Hampshire x Chester White x Yorkshi...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/0739-7240(92)90029-w
更新日期:1992-04-01 00:00:00
abstract::The objective of the present study was to determine if dexamethasone (Dex; a potent synthetic glucocorticoid) treatment at birth would alter postnatal growth in neonatal pigs. Forty crossbred pigs were injected i.m. with either sterile saline (Cont; n = 10 males and 10 females) or Dex (1 mg/kg; n = 10 males and 10 fem...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/s0739-7240(01)00107-2
更新日期:2001-08-01 00:00:00
abstract::Fecal corticosterone metabolites and plasma corticosterone in Japanese quail selected for low- or high-plasma corticosterone responses to brief mechanical restraint (low- and high-stress lines), and in a line of unselected quail, were measured in this study. No line differences were observed in baseline plasma cortico...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2012.01.002
更新日期:2012-05-01 00:00:00
abstract::Three experiments were conducted to better understand why milking-induced prolactin (PRL) release decreases as lactation advances. Experiment 1 compared the effects of milking, 2-min manual stimulation of the mammary gland (without milking), or injection of 1 IU of oxytocin (without milking) on hormonal release in ear...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2018.10.003
更新日期:2019-01-01 00:00:00
abstract::GnRH has several direct actions on rat granulosa cells. Specific receptors for GnRH have been demonstrated on rat and human ovaries. Whether the porcine ovary has specific receptors for GnRH is still debated and the physiological actions of GnRH on porcine granulosa cells have not yet been clarified. Consequently, we ...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/0739-7240(90)90032-u
更新日期:1990-04-01 00:00:00
abstract::This study aimed to evaluate the effect of melatonin on the in vitro culture and maturation of isolated sheep early antral follicles. Isolated early antral follicles were cultured for 12 d in α-minimum essential medium (MEM+) alone (control) or α-MEM+ added with fixed different concentrations (100, 500, or 1,000 pg/mL...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2019.106386
更新日期:2020-04-01 00:00:00
abstract::The influence of phthalate esters di-2-ethylhexyl phthalate (DEHP) and mono-2-ethylhexyl phthalate (MEHP) on uterine prostaglandin (PGF2alpha and PGE2) and ovarian oxytocin secretion was investigated. Endometrial, granulosa, and luteal cells from cows on days 8-12 of the estrous cycle were treated with DEHP or MEHP (0...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2010.03.002
更新日期:2010-08-01 00:00:00
abstract::The aim of the present study was to describe the relationship between serum adiponectin concentration and peripheral tissue insulin response in dairy cows with a variable body condition score (BCS) during the dry period. Cows were selected at the beginning of the dry period based on BCS (BCS <3.75, n = 4; BCS >3.75, n...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2016.12.004
更新日期:2017-04-01 00:00:00
abstract::In relevance to osmoregulatory and reproductive functions, activity of hypothalamic neurosecretory neurons may also vary seasonally. The current study was performed to determine annual changes in ir-AVT neurons of hypothalamus and adrenal gland function. We examined changes in ir-AVT neuron by immunohistochemical meth...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2007.08.003
更新日期:2008-04-01 00:00:00
abstract::Corpus luteum (CL), a transient endocrine gland critical for reproductive cyclicity and pregnancy maintenance, is controlled by numerous regulatory factors. Although LH is widely recognized as the major regulator, other factors may also affect luteal functions. It has been demonstrated that FSH receptors (FSHR) are ex...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2019.106391
更新日期:2020-04-01 00:00:00
abstract::Preliminary data suggest that prohormone convertase 1 (PC1/3) protein expression and proopiomelanocortin (POMC) processing are altered in large corticotroph tumors. The aim of this study was to characterize the levels of ACTH precursors and PC1/3 protein in small and large corticotroph tumors of dogs with Cushing's di...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2017.10.001
更新日期:2018-01-01 00:00:00
abstract::A simple extraction and assay technique of estrone sulfate in bovine blood was developed with the object of detecting the peripheral level of estrone sulfate in a normal estrous cycle or in early pregnancy. Estrone sulfate in bovine plasma was extracted with a small reversed phase cartridge. The steroid conjugate reta...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/0739-7240(96)00013-6
更新日期:1996-05-01 00:00:00
abstract::Crossbred ovariectomized ewes were treated with steroid therapies determined previously to be adequate (progesterone-primed) or inadequate (unprimed) for embryonic development in order to determine actual serum concentrations of replaced steroid hormones achieved by such treatments and to identify secreted endometrial...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/0739-7240(93)90017-6
更新日期:1993-04-01 00:00:00
abstract::We aimed to elucidate the effects of PGE2 and PGF2α on the in vitro maturation (IVM) of bovine oocytes. First, cumulus-oocyte complexes were matured in the media supplemented with or without PGE2, PGF2α, or PGE2 plus PGF2α for the final 24, 12, or 6 h of culture. Then, the cumulus-oocyte complexes were matured in the ...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2020.106447
更新日期:2020-07-01 00:00:00
abstract::Leptin, mainly produced in adipose tissue (AT), is a protein involved in the central and/or peripheral regulation of body homeostasis, energy intake, storage and expenditure, fertility and immune functions. Its role is well documented in rodent and human species, but less in ruminants. This review is focused on some i...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.domaniend.2005.02.026
更新日期:2005-07-01 00:00:00
abstract::Glucagon-like peptide-1 (GLP-1) is an intestinal hormone that induces glucose-dependent stimulation of insulin secretion while suppressing glucagon secretion. Glucagon-like peptide-1 also increases beta cell mass and satiation while decelerating gastric emptying. Liraglutide is a fatty-acid derivative of GLP-1 with a ...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2014.12.001
更新日期:2015-04-01 00:00:00
abstract::Since its discovery in 1994, leptin, a protein hormone synthesized and secreted by adipose tissue, has been shown to regulate feed intake in several species including sheep and pigs. Although a nimiety of information exists regarding the physiological role of leptin in rodents and humans, the regulation and action of ...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章,评审
doi:10.1016/s0739-7240(01)00120-5
更新日期:2001-11-01 00:00:00
abstract::In the dairy cow, puerperal uterine intra-luminal concentrations of PGE(2) are related to the establishment and severity of uterine infections. Here we evaluated whether the blood concentrations of PGE(2) and the gene transcription profiles of enzymes involved in its synthesis (cyclooxygenase-2 and prostaglandin E syn...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2008.07.001
更新日期:2008-10-01 00:00:00
abstract::The hormone progesterone is essential for proper embryonic development. The objective of this study was to examine the relationship between recipient serum concentrations of progesterone, at the time of embryo transfer and at conceptus recovery, on conceptus development from in vivo- or in vitro-produced embryos. Embr...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2015.03.004
更新日期:2015-07-01 00:00:00
abstract::The effects of estrogen and fasting on hepatic metabolism were studied by an arteriovenous difference technique in six multicatheterized ewes. In each experiment samples were collected during fed and 3- and 5-day fasted states before, and 10 to 17 days after the animals had been implanted with 550 mg of estradiol-17 b...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/0739-7240(88)90020-3
更新日期:1988-04-01 00:00:00
abstract::The aim of this study was to determine the effects of growth hormone (GH) and insulin-like growth factor (IGF)-I on glycerol release and the regulation of IGF-I and IGF-II expression by GH in isolated rainbow trout adipocytes. Cells were also incubated with GH, tumor necrosis factor α (TNFα), or insulin to analyze the...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2014.11.002
更新日期:2015-04-01 00:00:00
abstract::beta-Casein (CSN2) is a major milk protein in most mammals. The CSN2 gene is generally induced by lactogenic hormones bound to its promoter. The expression of this gene can be enhanced by signal transducers and activators of transcription (STAT) and glucocorticoid receptor (GR). Here, we analyzed the promoter and intr...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2008.04.001
更新日期:2008-10-01 00:00:00
abstract::Water buffaloes are easily adaptable animals, whose raising and economical exploitation have been growing in the last three decades all over the world. Hyperstimulation of ovarian function in this species is a common technique aiming to improve reproductive performance. Superovulatory treatment affects corpus luteum (...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2006.07.003
更新日期:2007-11-01 00:00:00
abstract::The embryo of the domestic fowl (Gallus domesticus) tenders one distinctive advantage over general mammalian models for investigating the development of the hypothalamo-pituitary-adrenocortical (HPA) axis. This is the relative simplicity with which the embryonic endocrine environment can be influenced without confound...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.domaniend.2004.01.001
更新日期:2004-05-01 00:00:00
abstract::Nesfatin-1 is a naturally occurring 82-amino acid protein encoded in the precursor nucleobindin-2 (NUCB2) and has been implicated in multiple physiological functions, including food intake and blood glucose regulation. This study aimed to characterize nesfatin-1 in domestic species, especially cats (Felis catus), dogs...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2018.04.006
更新日期:2018-10-01 00:00:00
abstract::In swine, colostrum production is induced by the drop of progesterone (P4) concentrations which leads to the prepartum peak of prolactin (PRL). PRL regulates mammary cell turnover and stimulates lacteal nutrient synthesis. P4 inhibits PRL secretion and downregulates the PRL receptor in the mammary gland. The aim of th...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2015.04.005
更新日期:2015-10-01 00:00:00
abstract::It has now been well documented that the normal and tumorous canine mammary glands can be extra-pituitary sites of substantial growth hormone (GH) synthesis. Until now, attempts to reproduce the GH synthesis in-vitro using canine mammary explants or mammary tumor cells have not been successful. Therefore, the response...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/s0739-7240(01)00088-1
更新日期:2001-02-01 00:00:00
abstract::Highly prolific sows often experience peripartum hypophagia, resulting in decreased production rate. Leptin, ghrelin, and resistin are known as feed intake-regulating hormones in many species, but it is yet unknown how feeding strategy and body condition will affect these hormones around parturition in sows. In the pr...
journal_title:Domestic animal endocrinology
pub_type: 杂志文章
doi:10.1016/j.domaniend.2013.04.003
更新日期:2013-07-01 00:00:00